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Volumn 28, Issue 3, 2013, Pages 351-364

Pharmacological treatment of neonatal seizures: A systematic review

Author keywords

antiepileptic drugs; levetiracetam; lidocaine; lorazepam; midazolam; neonatal seizures; paraldehyde; phenobarbital; phenytoin; thiopental

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE; CLONAZEPAM; DIAZEPAM; ETIRACETAM; LIDOCAINE; LORAZEPAM; MIDAZOLAM; PARALDEHYDE; PHENOBARBITAL; PHENYTOIN; PYRIDOXINE; THIOPENTAL;

EID: 84873639619     PISSN: 08830738     EISSN: 17088283     Source Type: Journal    
DOI: 10.1177/0883073812470734     Document Type: Article
Times cited : (93)

References (55)
  • 1
    • 0028918993 scopus 로고
    • A population-based study of neonatal seizures in Fayette County, Kentucky
    • Lanska MJ, Lanska DJ, Baumann RJ, Kryscio RJ. A population-based study of neonatal seizures in Fayette County, Kentucky. Neurology. 1995 ; 45: 724-732
    • (1995) Neurology , vol.45 , pp. 724-732
    • Lanska, M.J.1    Lanska, D.J.2    Baumann, R.J.3    Kryscio, R.J.4
  • 2
    • 0032912953 scopus 로고    scopus 로고
    • The epidemiology of clinical neonatal seizures in Newfoundland: A population-based study
    • DOI 10.1016/S0022-3476(99)70374-4
    • Ronen GM, Penney S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: A population-based study. J Pediatr. 1999 ; 134: 71-75 (Pubitemid 29048682)
    • (1999) Journal of Pediatrics , vol.134 , Issue.1 , pp. 71-75
    • Ronen, G.M.1    Penney, S.2    Andrews, W.3
  • 4
    • 59649111265 scopus 로고    scopus 로고
    • Neonatal seizures: Treatment and treatment variability in 31 United States pediatric hospitals
    • Blume HK, Garrison MM, Christakis DA. Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals. J Child Neurol. 2009 ; 24: 148-154
    • (2009) J Child Neurol , vol.24 , pp. 148-154
    • Blume, H.K.1    Garrison, M.M.2    Christakis, D.A.3
  • 5
    • 16644393806 scopus 로고    scopus 로고
    • Anticonvulsants for neonates with seizures
    • Booth D, Evans DJ.. Anticonvulsants for neonates with seizures. Cochrane Database Syst Rev. 2004 ; (4). CD004218
    • (2004) Cochrane Database Syst Rev , Issue.4 , pp. 004218
    • Booth, D.1    Evans, D.J.2
  • 6
    • 22044453126 scopus 로고    scopus 로고
    • Neonatal seizures: To treat or not to treat?
    • DOI 10.1016/j.spen.2005.03.004, PII S1071909105000410, New Vistas in Pediatric Epilepsy
    • Wirrell EC. Neonatal seizures: to treat or not to treat?. Semin Pediatr Neurol. 2005 ; 12: 97-105 (Pubitemid 40967987)
    • (2005) Seminars in Pediatric Neurology , vol.12 , Issue.2 , pp. 97-105
    • Wirrell, E.C.1
  • 7
    • 47049102489 scopus 로고    scopus 로고
    • Off-Label Use of Antiepileptic Drugs for the Treatment of Neonatal Seizures
    • DOI 10.1016/j.pediatrneurol.2008.04.008, PII S0887899408001914
    • Silverstein FS, Ferriero DM. Off-label use of antiepileptic drugs for the treatment of neonatal seizures. Pediatr Neurol. 2008 ; 39: 77-79 (Pubitemid 351970659)
    • (2008) Pediatric Neurology , vol.39 , Issue.2 , pp. 77-79
    • Silverstein, F.S.1    Ferriero, D.M.2
  • 9
    • 0032915040 scopus 로고    scopus 로고
    • Does perinatal phenobarbital exposure affect developmental outcome at age 2?
    • Thorp JA, O'Connor M, Jones A, et al. Does perinatal phenobarbital exposure affect developmental outcome at age 2?. Am J Perinatol. 1999 ; 16: 51
    • (1999) Am J Perinatol , vol.16 , pp. 51
    • Thorp, J.A.1    O'Connor, M.2    Jones, A.3
  • 11
    • 84867097850 scopus 로고    scopus 로고
    • Neonatal exposure to antiepileptic drugs disrupts striatal synaptic development
    • Forcelli PA, Janssen MJ, Vicini S, Gale K. Neonatal exposure to antiepileptic drugs disrupts striatal synaptic development. Ann Neurol. 2012 ; 72: 363-372
    • (2012) Ann Neurol , vol.72 , pp. 363-372
    • Forcelli, P.A.1    Janssen, M.J.2    Vicini, S.3    Gale, K.4
  • 12
    • 69449100622 scopus 로고    scopus 로고
    • Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. BMJ. 2009 ; 339: b2535
    • (2009) BMJ , vol.339 , pp. 2535
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 14
    • 44049097334 scopus 로고    scopus 로고
    • Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures
    • Murray DM, Boylan GB, Ali I, et al. Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures. Arch Dis Child Fetal Neonatal Ed. 2008 ; 93: F187 - F191
    • (2008) Arch Dis Child Fetal Neonatal Ed , vol.93
    • Murray, D.M.1    Boylan, G.B.2    Ali, I.3
  • 15
    • 69149101794 scopus 로고    scopus 로고
    • Interobserver agreement in neonatal seizure identification
    • Malone A, Anthony Ryan C, Fitzgerald A, et al. Interobserver agreement in neonatal seizure identification. Epilepsia. 2009 ; 50: 2097-2101
    • (2009) Epilepsia , vol.50 , pp. 2097-2101
    • Malone, A.1    Anthony Ryan, C.2    Fitzgerald, A.3
  • 16
    • 76049118313 scopus 로고    scopus 로고
    • Effect of treatment of subclinical neonatal seizures detected with aEEG: Randomized, controlled trial
    • van Rooij LGM, Toet MC, van Huffelen AC, et al. Effect of treatment of subclinical neonatal seizures detected with aEEG: randomized, controlled trial. Pediatrics. 2010 ; 125: e358 - e366
    • (2010) Pediatrics , vol.125
    • Van Rooij Lgm1    Toet, M.C.2    Van Huffelen, A.C.3
  • 17
    • 1042265060 scopus 로고    scopus 로고
    • Second-line anticonvulsant treatment of neonatal seizures
    • Boylan G, Rennie J, Chorley G, et al. Second-line anticonvulsant treatment of neonatal seizures. Neurology. 2004 ; 62: 486-488
    • (2004) Neurology , vol.62 , pp. 486-488
    • Boylan, G.1    Rennie, J.2    Chorley, G.3
  • 19
    • 14644410361 scopus 로고    scopus 로고
    • Midazolam in neonatal seizures with no response to phenobarbital
    • Castro-Conde JR, Borges AAH, Martinez ED, et al. Midazolam in neonatal seizures with no response to phenobarbital. Neurology. 2005 ; 64: 876-879
    • (2005) Neurology , vol.64 , pp. 876-879
    • Castro-Conde, J.R.1    Aah, B.2    Martinez, E.D.3
  • 20
    • 34249855664 scopus 로고    scopus 로고
    • Comparison of continuous drip of midazolam or lidocaine in the treatment of intractable neonatal seizures
    • DOI 10.1177/0883073807299858
    • Shany E, Benzaqen O, Watemberg N. Comparison of continuous drip of midazolam or lidocaine in the treatment of intractable neonatal seizures. J Child Neurol. 2007 ; 22: 255-259 (Pubitemid 46860552)
    • (2007) Journal of Child Neurology , vol.22 , Issue.3 , pp. 255-259
    • Shany, E.1    Benzaqen, O.2    Watemberg, N.3
  • 21
    • 0022517851 scopus 로고
    • Lorazepam in the treatment of refractory neonatal seizures: A pilot study
    • Deshmukh A, Wittert W, Schnitzler E, Mangurten HH. Lorazepam in the treatment of refractory neonatal seizures: A pilot study. Am J Dis Child. 1986 ; 140: 1042
    • (1986) Am J Dis Child , vol.140 , pp. 1042
    • Deshmukh, A.1    Wittert, W.2    Schnitzler, E.3    Mangurten, H.H.4
  • 23
    • 0025003874 scopus 로고
    • Thiopental efficacy in phenobarbital-resistant neonatal seizures
    • Bonati M, Marraro G, Celardo A, et al. Thiopental efficacy in phenobarbital-resistant neonatal seizures. Dev Pharmacol Ther. 1990 ; 15: 16
    • (1990) Dev Pharmacol Ther , vol.15 , pp. 16
    • Bonati, M.1    Marraro, G.2    Celardo, A.3
  • 24
    • 0026051668 scopus 로고
    • Lorazepam in the treatment of refractory neonatal seizures
    • Maytal J, Novak GP, King KC. Lorazepam in the treatment of refractory neonatal seizures. J Child Neurol. 1991 ; 6: 319-323
    • (1991) J Child Neurol , vol.6 , pp. 319-323
    • Maytal, J.1    Novak, G.P.2    King, K.C.3
  • 25
    • 0029591860 scopus 로고
    • Electroencephalograms, clinical observations and the monitoring of neonatal seizures
    • Bye A, Flanagan D. Electroencephalograms, clinical observations and the monitoring of neonatal seizures. J Paediatr Child Health. 1995 ; 31: 503-507 (Pubitemid 26019299)
    • (1995) Journal of Paediatrics and Child Health , vol.31 , Issue.6 , pp. 503-507
    • Bye, A.1    Flanagan, D.2
  • 26
    • 0029926697 scopus 로고    scopus 로고
    • Midazolam in the treatment of refractory neonatal seizures
    • Sheth RD, Buckley DJ, Gutierrez AR, et al. Midazolam in the treatment of refractory neonatal seizures. Clin Neuropharmacol. 1996 ; 19: 165
    • (1996) Clin Neuropharmacol , vol.19 , pp. 165
    • Sheth, R.D.1    Buckley, D.J.2    Gutierrez, A.R.3
  • 31
    • 79952549970 scopus 로고    scopus 로고
    • Use of intravenous levetiracetam for management of acute seizures in neonates
    • Khan O, Chang E, Cipriani C, et al. Use of intravenous levetiracetam for management of acute seizures in neonates. Pediatr Neurol. 2011 ; 44: 265-269
    • (2011) Pediatr Neurol , vol.44 , pp. 265-269
    • Khan, O.1    Chang, E.2    Cipriani, C.3
  • 32
    • 33745543980 scopus 로고    scopus 로고
    • Summary proceedings from the neurology group on neonatal seizures
    • Clancy RR. Summary proceedings from the neurology group on neonatal seizures. Pediatrics. 2006 ; 117: S23 - S27
    • (2006) Pediatrics , vol.117
    • Clancy, R.R.1
  • 33
    • 33846919562 scopus 로고    scopus 로고
    • The FDA takes action against unapproved drugs
    • Meadow M. The FDA takes action against unapproved drugs. FDA Consumer Magazine. 2007 ; ( January-February ):
    • (2007) FDA Consumer Magazine , Issue.JANUARY-FEBRUARY
    • Meadow, M.1
  • 35
    • 0020321056 scopus 로고
    • Prolonged seizures associated with the use of viscous lidocaine
    • DOI 10.1016/S0022-3476(82)80088-7
    • Rothstein P, Dornbusch J, Shaywitz BA. Prolonged seizures associated with the use of viscous lidocaine. J Pediatr. 1982 ; 101: 461-463 (Pubitemid 12061478)
    • (1982) Journal of Pediatrics , vol.101 , Issue.3 , pp. 461-463
    • Rothstein, P.1    Dornbusch, J.2    Shaywitz, B.A.3
  • 36
    • 0032060405 scopus 로고    scopus 로고
    • Recurrent Seizures in a Neonate after Lidocaine Administration
    • Resar LM, Helfaer MA. Recurrent seizures in a neonate after lidocaine administration. J Perinatol. 1998 ; 18: 193-195 (Pubitemid 128451699)
    • (1998) Journal of Perinatology , vol.18 , Issue.3 , pp. 193-195
    • Resar, L.M.S.1    Helfaer, M.A.2
  • 37
    • 84965358957 scopus 로고
    • Sinoatrial arrest: An interaction between phenytoin and lignocaine
    • Wood RA. Sinoatrial arrest: an interaction between phenytoin and lignocaine. Br Med J. 1971 ; 1: 645
    • (1971) Br Med J , vol.1 , pp. 645
    • Wood, R.A.1
  • 38
    • 0017358523 scopus 로고
    • Pharmacokinetic observations of phenytoin disposition in the newborn and young infant
    • Loughnan PM, Greenwald A, Purton WW, et al. Pharmacokinetic observations of phenytoin disposition in the newborn and young infant. Arch Dis Child. 1977 ; 52: 302-309 (Pubitemid 8080204)
    • (1977) Archives of Disease in Childhood , vol.52 , Issue.4 , pp. 302-309
    • Loughnan, P.M.1    Greenwald, A.2    Purton, W.W.3
  • 40
    • 0000781010 scopus 로고
    • The blood volume of the newborn infant and placental transfusion
    • Usher R, Shephard M, Lind J. The blood volume of the newborn infant and placental transfusion. Acta Paediatrica. 1963 ; 52: 497-512
    • (1963) Acta Paediatrica , vol.52 , pp. 497-512
    • Usher, R.1    Shephard, M.2    Lind, J.3
  • 41
    • 0001192621 scopus 로고
    • Blood volume of the newborn premature infant
    • Usher R, Lind J. Blood volume of the newborn premature infant. Acta Paediatrica. 1965 ; 54: 419-431
    • (1965) Acta Paediatrica , vol.54 , pp. 419-431
    • Usher, R.1    Lind, J.2
  • 43
    • 80051788400 scopus 로고    scopus 로고
    • Red blood cell transfusions are independently associated with intra-hospital mortality in very low birth weight preterm infants
    • dos Santos AMN, Guinsburg R, de Almeida MFB, et al. Red blood cell transfusions are independently associated with intra-hospital mortality in very low birth weight preterm infants. J Pediatr. 2011 ; 159: 371-376
    • (2011) J Pediatr , vol.159 , pp. 371-376
    • Santos Amn, D.1    Guinsburg, R.2    De Almeida Mfb3
  • 44
    • 79951575831 scopus 로고    scopus 로고
    • Transfusion-related acute gut injury: Necrotizing enterocolitis in very low birth weight neonates after packed red blood cell transfusion
    • Blau J, Calo JM, Dozor D, et al. Transfusion-related acute gut injury: necrotizing enterocolitis in very low birth weight neonates after packed red blood cell transfusion. J Pediatr. 2011 ; 158: 403-409
    • (2011) J Pediatr , vol.158 , pp. 403-409
    • Blau, J.1    Calo, J.M.2    Dozor, D.3
  • 45
    • 79953319603 scopus 로고    scopus 로고
    • Increased odds of necrotizing enterocolitis after transfusion of red blood cells in premature infants
    • Paul DA, Mackley A, Novitsky A, et al. Increased odds of necrotizing enterocolitis after transfusion of red blood cells in premature infants. Pediatrics. 2011 ; 127: 635-641
    • (2011) Pediatrics , vol.127 , pp. 635-641
    • Paul, D.A.1    MacKley, A.2    Novitsky, A.3
  • 46
    • 84873642633 scopus 로고    scopus 로고
    • US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research Accessed October 5, 2012
    • US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research. Application number NDA 21505/S-026. Available at: http://www.accessdata.fda.gov. Accessed October 5, 2012.
    • Application Number NDA 21505/S-026
  • 47
    • 0031875719 scopus 로고    scopus 로고
    • Clinical pharmacology of midazolam in infants and children
    • DOI 10.2165/00003088-199835010-00003
    • Blumer JL. Clinical pharmacology of midazolam in infants and children. Clin Pharmacokinet. 1998 ; 35: 37-47 (Pubitemid 28318961)
    • (1998) Clinical Pharmacokinetics , vol.35 , Issue.1 , pp. 37-47
    • Blumer, J.L.1
  • 49
    • 47649086505 scopus 로고    scopus 로고
    • Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop report
    • Silverstein FS, Jensen FE, Inder T, et al. Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop report. J Pediatr. 2008 ; 153: 12-15
    • (2008) J Pediatr , vol.153 , pp. 12-15
    • Silverstein, F.S.1    Jensen, F.E.2    Inder, T.3
  • 51
    • 84873674669 scopus 로고    scopus 로고
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Center for Research Resources Accessed October 5, 2012
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Center for Research Resources. Laparotomy vs. drainage for infants with necrotizing enterocolitis (NEST). Available at: http://clinicaltrials.gov/ct2/show/NCT01029353?term=nest&rank=1. Accessed October 5, 2012.
    • Laparotomy Vs. Drainage for Infants with Necrotizing Enterocolitis (NEST)
  • 52
    • 84873658720 scopus 로고    scopus 로고
    • National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development Accessed October 5, 2012
    • National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development. Neonatal Research Network. Available at: http://neonatal.rti.org/. Accessed October 5, 2012.
    • Neonatal Research Network
  • 53
    • 84873645094 scopus 로고    scopus 로고
    • National Institutes of Health, National Institute of Neurological Disorders and Stroke Accessed October 5, 2012
    • National Institutes of Health, National Institute of Neurological Disorders and Stroke. NeuroNEXT: Network for Excellence in Neuroscience Clinical Trials. Available at: http://www.neuronext.org/. Accessed October 5, 2012.
    • NeuroNEXT: Network for Excellence in Neuroscience Clinical Trials
  • 54
    • 33644763919 scopus 로고    scopus 로고
    • What is the best evidence for determining harms of medical treatment?
    • DOI 10.1503/cmaj.051484
    • Vandenbroucke JP. What is the best evidence for determining harms of medical treatment?. Can Med Assoc J. 2006 ; 174: 645-646 (Pubitemid 43341875)
    • (2006) Canadian Medical Association Journal , vol.174 , Issue.5 , pp. 645-646
    • Vandenbroucke, J.P.1
  • 55
    • 77949651908 scopus 로고    scopus 로고
    • AHRQ series paper 4: Assessing harms when comparing medical interventions: AHRQ and the effective health-care program
    • Chou R, Aronson N, Atkins D, et al. AHRQ series paper 4: assessing harms when comparing medical interventions: AHRQ and the effective health-care program. J Clin Epidemiol. 2010 ; 63: 502-512
    • (2010) J Clin Epidemiol , vol.63 , pp. 502-512
    • Chou, R.1    Aronson, N.2    Atkins, D.3


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