Prohibitin induces apoptosis in BGC823 gastric cancer cells through the mitochondrial pathway

Asian Pacific Journal of Cancer Prevention

Volumn 13, Issue 8, 2012, Pages 3803-3807

  Zhang, Long ^a   Ji, Qing ^a   Ni, Zhen Hua ^a   Sun, Jian ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Apoptosis; Bgc823; Mitochondrial pathway; Prohibitin

Indexed keywords

EID: 84873622449     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.8.3803     Document Type: Article

References (21)

1. Alenzi FQ, Lotfy M, Wyse R (2010). Swords of cell death: caspase activation and regulation. Asian Pac J Cancer Prev, 11, 271-80
2. Artal-Sanz M, Tsang WY, Willems, et al (2003). The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans. J Biol Chem, 27, 32091-99.
3. Berger KH, MP Yaffe (1998). Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae. Molec Cellular Biol, 18, 4043-52.
4. Coates PJ, Jamieson DJ, Smart K, et al (1997). The prohibitin family of mitochondrial proteins regulate replicative lifespan. Current Biology, 7607-10.
5. Fang Min, Wang Xiaodong (2002). Mitochondrial apoptosis pathway. J Peking University (Health Sciences), 34, 1-7.
6. Ikonen E, Fiedler K, Parton RG, et al (1995). Prohibitin, an antiproliferative protein, is localized to mitochondria. FEBS Letters, 35, 8273-7.
7. Ji Qi, Zhang Long, Sun Jian, et al (2010). Investigation on expression level of PHBI in gastric and colorectal cancer by real time PCR. Lab Med Clin, 7332-3.
8. Jorg M, Angela P, Peter S, et al (2004). Differential immunization identifies PHB1/PHB2 as blood-borne tumor antigens. Oncogene, 23, 7430-5.
9. Jupe ER, Liu XT, Kiehlbauch JL, et al (1996). The 3' untranslated region of prohibitin and cellular immortalization. Exp Cell Res, 22, 4128-35.
10. Kang X, Zhang L, Sun J, et al (2008). Prohibitin: a potential biomarker for tissue-based detection of gastric cancer. J Gastroenterol, 43, 618-25.
11. Kang X, Zhang L, Wu R, et al (2006). The expression of Prohibitin in gastrointestinal cancer tissue and its clinical significance. Lab Med, 21, 610-2.
12. Korsmeyer SJ, Wei MC, Saito M, et al (2000). Pro-apoptotic cascade activates BID, which oligomerizes BAKor BAX into pores that result in the release of cytochrome-c. Cell Death Differ, 71, 166-73.
13. Leo GJ, Liesbeth DJ, Marta AS, et al (2000). Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins. EMBO J, 19, 2444-51
14. Nora M, Alicia G, Mariel N, et al (2005). Mitochondrial apoptotic pathways. Biocell, 29, 149-61
15. Ren H, Du N, Liu G, et al (2006). Analysis of variabilities of serum proteomic spectra in patients with gastric cancer before and after operation. World J Gastroenterol, 12, 2789-92.
16. Shi CL, Yu CH, Zhang Y, et al (2011). Monocyte chemoattractant protein-1 modulates invasion and apoptosis of PC-3M prostate cancer cells via regulating expression of VEGF, MMP9 and caspase-3. Asian Pac J Cancer Prev, 12, 555-9
17. Snedden WA, Fromm H (1997). Characterization of the plant homologue of prohibitin, a gene associated with antiproliferative activity in mammalian cells. Plant Molecular Biology, 33, 753-6.
18. Spurdle AB, Hopper JL, Chen XQ, et al (2002). Prohibitin 3' untranslated region polymorphism and breast cancer risk in Australian women. Lancet, 360, 925-26.
19. Sun ZL, Zhu Y, Wang FQ (2007). Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers. Biochimica et Biophysica Acta, 1774, 764-71.
20. Wolf B, Sehuler M, Eeheverrl F, et a1 (1999). Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragment factor45/inhibitor of caspase activated DNase activation. Biol Chem, 274, 30651-6.
21. Zhang L, Ni Z, Wu R, et al (2009). Expression of Prohibitin and application of recombinant Prohibitin in serologic diagnosis. Contemporary Med, 77, 1-4.