Implementation of the glucommander method of adjusting insulin infusions in critically ill patients

Canadian Journal of Hospital Pharmacy

Volumn 64, Issue 5, 2011, Pages 333-339

  Yamashita, Sharon ^a   Ng, Emily ^a,b   Brommecker, Frank ^a   Silverberg, Jay ^a   Adhikari, Neill K J ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b McCarthy Tétrault LLP   (Canada)

Author keywords

Critically ill patients; Tight glycemic control

Indexed keywords

GLUCOSE; INSULIN;

AGED; ALGORITHM; ARTICLE; CARDIOVASCULAR SURGERY; CLINICAL ARTICLE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; FEMALE; GLUCOMMANDER SYSTEM; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INSULIN INFUSION; INTENSIVE CARE UNIT; INTERMETHOD COMPARISON; MALE; NOMOGRAM; NURSING; PATIENT SATISFACTION; WORKLOAD;

EID: 84873593152     PISSN: 00084123     EISSN: 19202903     Source Type: Journal    
DOI: 10.4212/cjhp.v64i5.1068     Document Type: Article

References (14)

1. Mizock BA. Alterations in fuel metabolism in critical illness: hyperglycemia. Best Pract Res Clin Endocrinol Metab 2001;15(4): 533-551.
2. Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001;345(19): 1359-1367.
3. Van den Berghe G, Wilmer A, Hermans G, Meersseman W, Wouter PJ, Milants I, et al. Intensive insulin therapy in the medical ICU. N Engl J Med 2006;354(5): 449-461. (Pubitemid 43200296)
4. Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008;358(2): 125-139.
5. NICE-SUGAR Study Investigators. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009;360(12): 1283-1297.
6. Griesdale DGE, de Souza RJ, van Dam RM, Heyland DK, Cook DJ, Malhotra A, et al. Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data. CMAJ 2009;180(8): 821-827.
7. Davidson PC, Steed RD, Bode BW. Glucommander: a computer-directed intravenous insulin system shown to be safe, simple, and effective in 120,618 h of operation. Diabetes Care 2005;28(10): 2418-2423. (Pubitemid 41384287)
8. Bode BW, Braithwaite SS, Steed RD, Davidson PC. Intravenous insulin infusion therapy: indications, methods and transition to subcutaneous insulin therapy. Endocr Pract 2004;10 Suppl 2: 71-80.
9. Knaus WA, Wagner DP, Draper EA, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985;13(10): 818-829. (Pubitemid 15250137)
10. Service FJ, Molnar GD, Rosevear JW, Ackerman E, Gatewood LC, Taylor WF. Mean amplitude of glycemic excursions, a measure of diabetic instability. Diabetes 1970;19(9): 644-655.
11. Egi M, Bellomo R, Stachowski E, French CJ, Hart G. Variability of blood glucose concentration and short-term mortality in critically ill patients. Anaesthesiology 2006;105(2): 244-252. (Pubitemid 44148168)
12. Krinsley JS. Glycemic variability: a strong independent predictor of mortality in critically ill patients. Crit Care Med 2008;36(11): 3008-3013.
13. Chant C, Wilson G, Friedrich JO. Validation of an insulin infusion nomogram for intensive glucose control in critically ill patients. Pharmacotherapy 2005;25(3): 352-359. (Pubitemid 40300322)
14. Moghissi ES, Korytkowski MT, DiNardo M, Einhorn D, Hellman R, Hirsh IB, et al. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement of inpatient glycemic control. Diabetes Care 2009;32(6): 1119-1131.