Desmopressin testing in haemo-philia A patients and carriers: Results of a multi centre survey

Hamostaseologie

Volumn 32, Issue 4, 2012, Pages 271-275

  Knofler R ^a   Koscielny, J ^b   Tauer, J T ^a   Huhn, B ^a   Gneuss, A ^a   Kuhlisch, E ^c   Hofmann, A ^d   Petros, S ^e   Aumann, V ^f   Franke, D ^g   Kentouche, K ^h   Syrbe, G ⁱ   Seeger, K ^b   Haberland, H ^j   Klamroth, R ^k  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d Municipal Hospital Chemnitz   (Germany)

^e UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^f UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

^g Practice of Internal Medicine and Angiology   (Germany)

^h JENA UNIVERSITY HOSPITAL   (Germany)

ⁱ Asklepios Hospital Stadtroda   (Germany)

^j SANA KLINIKUM OFFENBACH   (Germany)

^k VIVANTES KLINIKUM IM FRIEDRICHSHAIN   (Germany)

more..

Author keywords

Ddavp; Desmopressin testing; Haemophilia A

Indexed keywords

BLOOD CLOTTING FACTOR 8; DESMOPRESSIN; ARGIPRESSIN[1 DEAMINO]; BIOLOGICAL MARKER; F8 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL EVALUATION; DIAGNOSTIC TEST; DISCOMFORT; FEMALE; FLUSHING; HEADACHE; HEMOPHILIA A; HETEROZYGOTE; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; NAUSEA; PARAMETERS; PRESCHOOL CHILD; PROPHYLAXIS; SCHOOL CHILD; SIDE EFFECT; TREATMENT RESPONSE; AGED; BLOOD; GERMANY; METHODOLOGY; MIDDLE AGED; PREVALENCE; REPRODUCIBILITY; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; DEAMINO ARGININE VASOPRESSIN; FACTOR VIII; FEMALE; GERMANY; HEMOPHILIA A; HUMANS; MALE; MIDDLE AGED; PREVALENCE; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

EID: 84873592591     PISSN: 07209355     EISSN: None     Source Type: Journal    
DOI: 10.5482/HAMO-12-06-0012     Document Type: Article

References (28)

1. Lethagen S. Desmopressin in mild hemophilia A: indications, limitations, efficacy, and safety. Semin Thromb Hemost 2003; 29: 101-106.
2. Castaman G. Desmopressin for the treatment of haemophilia. Haemophilia 2008; 14 Suppl 1: 15-20.
3. Miesbach W, Krekeler S, Dück O et al. Clinical assessment of efficacy and safety of DDAVP. Hämostaseologie 2010; 30 (Suppl 1): S172-S175.
4. Sanchez-Luceros A, Meschengieser SS, Woods AI et al. Biological and clinical response to desmopressin (DDAVP) in a retrospective cohort study of children with low von Willebrand factor levels and bleeding history. Thromb Haemost 2010; 104: 984-989.
5. Hanebutt FL, Rolf N, Loesel A et al. Evaluation of desmopressin effects on haemostasis in children with congenital bleeding disorders. Haemophilia 2008; 14: 524-530.
6. Revel-Vilk S, Blanchette VS, Sparling C et al. DDAVP challenge tests in boys with mild/moderate haemophilia A. Br J Haematol 2002; 117: 947-951.
7. Nolan B, White B, Smith J et al. Desmopressin: therapeutic limitations in children and adults with inherited coagulation disorders. Br J Haematol 2000; 109: 865-869.
8. Lethagen S, Harris AS, Sjorin E, Nilsson IM. Intranasal and intravenous administration of desmopressin: effect on FVIII/VWF, pharmacokinetics and reproducibility. Thromb Haemost 1987; 58: 1033-1036.
9. Lethagen S, Harris AS, Nilsson IM. Intranasal desmopressin (DDAVP) by spray in mild hemophilia A and von Willebrand's disease type I. Blut 1990; 60: 187-191.
10. Mannucci PM, Vicente V, Alberca I et al. Intravenous and subcutaneous administration of desmopressin (DDAVP) to hemophiliacs: pharmacokinetics and factor VIII responses. Thromb Haemost 1987; 58: 1037-1039.
11. Seary ME, Feldman D, Carcao MD. DDAVP responsiveness in children with mild or moderate haemophilia A correlates with age, endogenous FVIII:C level and with haemophilic genotype. Haemo philia 2012; 18: 50-55.
12. Castaman G, Mancuso ME, Giacomelli SH et al. Molecular and phenotypic determinants of the response to desmopressin in adult patients with mild hemophilia A. J Thromb Haemost 2009; 7: 1824-1831.
13. De la Fuente B, Kasper CK, Rickles FR, Hoyer LW. Response of patients with mild and moderate hemophilia A and von Willebrand's disease to treatment with desmopressin. Ann Intern Med 1985; 103: 6-14.
14. Rodeghiero F, Castaman G, Di Bona E, Ruggeri M. Consistency of responses to repeated DDAVP infusions in patients with von Willebrand's disease and hemophilia A. Blood 1989; 74: 1997-2000.
15. Tagliaferri A, Di Perna C, Riccardi F et al. The natural history of mild haemophilia: a 30-year single centre experience. Haemophilia 2012; 18: 166-174.
16. Castaman G, Giacomelli SH, Mancuso ME et al. Deep intronic variations may cause mild hemophilia A. J Thromb Haemost 2011; 9: 1541-1548.
17. Mannucci PM. Desmopressin (DDAVP) for treatment of disorders of hemostasis. Prog Hemost Thromb 1986; 8: 19-45.
18. Gillam PMS. Desmopressin and arterial thrombosis. Lancet 1989; 1: 938-939.
19. Cattaneo M, Mannucci PM. Desmopressin and blood loss after cardiac surgery. Lancet 1993; 342: 812.
20. Mannucci PM, Lusher JM. Desmopressin and thrombosis. Lancet 1989; 2: 675-676.
21. O'Brien JR, Green PJ, Salmon G et al. Desmopressin and myocardial infarction. Lancet 1989; 1: 664-665.
22. Bond L, Bevan D. Myocardial infarction in a patient with hemophilia treated with DDAVP. N Engl J Med 1988; 318: 121.
23. Lowe G, Pettigrew A, Middleton S et al. DDAVP in haemophilia. Lancet 1977; 2: 614-615.
24. Shepherd LL, Hutchinson RJ, Worden EK et al. Hyponatremia and seizures after intravenous administration of desmopressin acetate for surgical hemostasis. J Pediatr 1989; 114: 470-472.
25. Salvatoni A, Maghnie M, Lorini R, Marni E. Hyponatremia and seizures during desmopressin acetate treatment in hypothyroidism. J Pediatr 1990; 116: 835-836.
26. Weinstein RE, Bona RD, Altman AJ et al. Severe hyponatremia after repeated intravenous administration of desmopressin. Am J Hematol 1989; 32: 258-261.
27. Smith TJ, Gill JC, Ambruso DR, Hathaway WE. Hyponatremia and seizures in young children given DDAVP. Am J Hematol 1989; 31: 199-202.
28. Huhn B, Hofmann A, Hofmann K et al. Desmopressin testing in children with von Willebrand syndrome in haemostaseologic centers of Saxonia, Saxonia-Anhalt and Thuringia. Hämostaseologie 2009; 29 (Suppl 1): S98-S102.