Leukocyte DNA as Surrogate for the Evaluation of Imprinted Loci Methylation in Mammary Tissue DNA

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Barault, Ludovic ^a   Ellsworth, Rachel E ^b   Harris, Holly R ^a   Valente, Allyson L ^c   Shriver, Craig D ^d   Michels, Karin B ^a,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Henry M Jackson Foundation for the Advancement of Military Medicine   (United States)

^c WINDBER RESEARCH INSTITUTE   (United States)

^d WALTER REED ARMY MEDICAL CENTER   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; LEUKOCYTE DNA; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; BREAST; BREAST CANCER; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA DETERMINATION; DNA METHYLATION; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE LOCUS; GENETIC CORRELATION; GENETIC MARKER; GENETIC VARIABILITY; GENOME IMPRINTING; GRB10 ICR GENE; H19 ICR GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IGF2 DMR0 GENE; IGF2 DMR2 GENE; KVDMR GENE; LEUKOCYTE; MAJOR CLINICAL STUDY; SNRPN GENE; TISSUE DISTRIBUTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CPG ISLANDS; DNA; DNA METHYLATION; FEMALE; GENETIC LOCI; GENOMIC IMPRINTING; HUMANS; LEUKOCYTES; MAMMARY GLANDS, HUMAN; MIDDLE AGED; YOUNG ADULT;

EID: 84873589803     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055896     Document Type: Article

References (36)

1. da Rocha ST, Ferguson-Smith AC, (2004) Genomic imprinting. Curr Biol 14: R646-649.
2. Murrell A, (2006) Genomic imprinting and cancer: from primordial germ cells to somatic cells. ScientificWorldJournal 6: 1888-1910.
3. Lewis A, Reik W, (2006) How imprinting centres work. Cytogenet Genome Res 113: 81-89.
4. Cassidy SB, Schwartz S (1993) Prader-Willi Syndrome.
5. Saal HM (1993) Russell-Silver Syndrome.
6. Shuman C, Beckwith JB, Smith AC, Weksberg R (1993) Beckwith-Wiedemann Syndrome.
7. Byun HM, Wong HL, Birnstein EA, Wolff EM, Liang G, et al. (2007) Examination of IGF2 and H19 loss of imprinting in bladder cancer. Cancer Res 67: 10753-10758.
8. Cui H, Cruz-Correa M, Giardiello FM, Hutcheon DF, Kafonek DR, et al. (2003) Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 299: 1753-1755.
9. Murphy SK, Huang Z, Wen Y, Spillman MA, Whitaker RS, et al. (2006) Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer. Mol Cancer Res 4: 283-292.
10. Dufresne AM, Smith RJ, (2005) The adapter protein GRB10 is an endogenous negative regulator of insulin-like growth factor signaling. Endocrinology 146: 4399-4409.
11. Ellis MJ, Jenkins S, Hanfelt J, Redington ME, Taylor M, et al. (1998) Insulin-like growth factors in human breast cancer. Breast Cancer Res Treat 52: 175-184.
12. Yoshimizu T, Miroglio A, Ripoche MA, Gabory A, Vernucci M, et al. (2008) The H19 locus acts in vivo as a tumor suppressor. Proc Natl Acad Sci U S A 105: 12417-12422.
13. Scelfo RA, Schwienbacher C, Veronese A, Gramantieri L, Bolondi L, et al. (2002) Loss of methylation at chromosome 11p15.5 is common in human adult tumors. Oncogene 21: 2564-2572.
14. Benetatos L, Hatzimichael E, Dasoula A, Dranitsaris G, Tsiara S, et al. (2010) CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes. Leuk Res 34: 148-153.
15. Ito Y, Koessler T, Ibrahim AE, Rai S, Vowler SL, et al. (2008) Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. Hum Mol Genet 17: 2633-2643.
16. Woodfine K, Huddleston JE, Murrell A, (2011) Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue. Epigenetics Chromatin 4: 1.
17. Guo L, Choufani S, Ferreira J, Smith A, Chitayat D, et al. (2008) Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae. Dev Biol 320: 79-91.
18. Dejeux E, El Abdalaoui H, Gut IG, Tost J, (2009) Identification and quantification of differentially methylated loci by the pyrosequencing technology. Methods Mol Biol 507: 189-205.
19. Monk D, (2010) Deciphering the cancer imprintome. Brief Funct Genomics 9: 329-339.
20. Uribe-Lewis S, Woodfine K, Stojic L, Murrell A, (2011) Molecular mechanisms of genomic imprinting and clinical implications for cancer. Expert Rev Mol Med 13: e2.
21. Dammann RH, Kirsch S, Schagdarsurengin U, Dansranjavin T, Gradhand E, et al. (2010) Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma. Int J Oncol 36: 171-179.
22. Murrell A, Ito Y, Verde G, Huddleston J, Woodfine K, et al. (2008) Distinct methylation changes at the IGF2-H19 locus in congenital growth disorders and cancer. PLoS One 3: e1849.
23. Cui H, Onyango P, Brandenburg S, Wu Y, Hsieh CL, et al. (2002) Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res 62: 6442-6446.
24. Frost JM, Monk D, Stojilkovic-Mikic T, Woodfine K, Chitty LS, et al. (2010) Evaluation of allelic expression of imprinted genes in adult human blood. PLoS One 5: e13556.
25. Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, et al. (2009) Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet 18: 4808-4817.
26. Talens RP, Boomsma DI, Tobi EW, Kremer D, Jukema JW, et al. (2010) Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. FASEB J 24: 3135-3144.
27. Kaaks R, Stattin P, Villar S, Poetsch AR, Dossus L, et al. (2009) Insulin-like growth factor-II methylation status in lymphocyte DNA and colon cancer risk in the Northern Sweden Health and Disease cohort. Cancer Res 69: 5400-5405.
28. Zhang D, Cheng L, Badner JA, Chen C, Chen Q, et al. (2010) Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet 86: 411-419.
29. Tobi EW, Slagboom PE, van Dongen J, Kremer D, Stein AD, et al. (2012) Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. PLoS One 7: e37933.
30. McCann AH, Miller N, O'Meara A, Pedersen I, Keogh K, et al. (1996) Biallelic expression of the IGF2 gene in human breast disease. Hum Mol Genet 5: 1123-1127.
31. Yballe CM, Vu TH, Hoffman AR, (1996) Imprinting and expression of insulin-like growth factor-II and H19 in normal breast tissue and breast tumor. J Clin Endocrinol Metab 81: 1607-1612.
32. Wu HK, Squire JA, Catzavelos CG, Weksberg R, (1997) Relaxation of imprinting of human insulin-like growth factor II gene, IGF2, in sporadic breast carcinomas. Biochem Biophys Res Commun 235: 123-129.
33. van Roozendaal CE, Gillis AJ, Klijn JG, van Ooijen B, Claassen CJ, et al. (1998) Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures. FEBS Lett 437: 107-111.
34. Yun K, Soejima H, Merrie AE, McCall JL, Reeve AE, (1999) Analysis of IGF2 gene imprinting in breast and colorectal cancer by allele specific-PCR. J Pathol 187: 518-522.
35. Yang R, Wang Y, Zhu X, Gao X, (2009) [Study on genomic imprinting of IGF2 in breast cancer]. Wei Sheng Yan Jiu 38: 423-425.
36. Shetty PJ, Movva S, Pasupuleti N, Vedicherlla B, Vattam KK, et al. (2011) Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer. J Cancer Res Clin Oncol 137: 339-345.