Alteration of serum miR-206 and miR-133b is associated with lung carcinogenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Toxicology and Applied Pharmacology

Volumn 267, Issue 3, 2013, Pages 238-246

  Wu, Jianjun ^a   Yang, Ti ^a   Li, Xun ^a   Yang, Qiaoyuan ^a   Liu, Rong ^a,b   Huang, Jinkun ^a,b   Li, Yuanqi ^a   Yang, Chengfeng ^c   Jiang, Yiguo ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

4 (Methylnitrosamino) 1 (3 pyridyl) 1 butanone; Lung carcinogenesis; MiR 133b; MiR 206; Serum

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; MICRORNA; MICRORNA 133B; MICRORNA 206; RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CANCER TISSUE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION PROFILING; LUNG CANCER; LUNG CARCINOGENESIS; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; RNA SEQUENCE; SERUM; SMALL RNA SOLEXA SEQUENCING;

ANIMALS; CARCINOGENS; LUNG NEOPLASMS; MALE; MICRORNAS; NITROSAMINES; RATS; RATS, INBRED F344; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84873587970     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.01.002     Document Type: Article

References (41)

1. Akopyan G., Bonavida B. Understanding tobacco smoke carcinogen NNK and lung tumorigenesis. Int. J. Oncol. 2006, 29(4):745-752.
2. Bollati V., Marinelli B., Apostoli P., Bonzini M., Nordio F., Hoxha M., Pegoraro V., Motta V., Tarantini L., Cantone L., Schwartz J., Bertazzi P.A., Baccarelli A. Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes. Environ. Health Perspect. 2010, 118(6):763-768.
3. Calin G.A., Croce C.M. MicroRNA signatures in human cancers. Nat. Rev. Cancer 2006, 6:857-866.
4. Chen X., Ba Y., Ma L., Cai X., Yin Y., Wang K., Guo J., Zhang Y., Chen J., Guo X., Li Q., Li X., Wang W., Zhang Y., Wang J., Jiang X., Xiang Y., Xu C., Zheng P., Zhang J., Li R., Zhang H., Shang X., Gong T., Ning G., Wang J., Zen K., Zhang J., Zhang C.Y. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008, 18(10):997-1006.
5. Chen X., Yan Q., Li S., Zhou L., Yang H., Yang Y., Liu X., Wan X. Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERα-positive endometrioid adenocarcinoma. Cancer Lett. 2012, 314(1):41-53.
6. Cimmino A., Calin G.A., Fabbri M., Iorio M.V., Ferracin M., Shimizu M., Wojcik S.E., Aqeilan R.I., Zupo S., Dono M., Rassenti L., Alder H., Volinia S., Liu C.G., Kipps T.J., Negrini M., Croce C.M. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. U. S. A. 2005, 102(39):13944-13949.
7. Haas J.D., Nistala K., Petermann F., Saran N., Chennupati V., Schmitz S., Korn T., Wedderburn L.R., Förster R., Krueger A., Prinz I. Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells. PLoS One 2011, 6(5):e20171.
8. Hayashita Y., Osada H., Tatematsu Y., Yamada H., Yanagisawa K., Tomida S., Yatabe Y., Kawahara K., Sekido Y., Takahashi T. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 2005, 65(21):9628-9632.
9. Hecht S.S. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem. Res. Toxicol. 1998, 11:559-603.
10. Hecht S.S. Tobacco smoke carcinogens and lung cancer. J. Natl. Cancer Inst. 1999, 91(14):1194-1210.
11. Hecht S.S., Trushin N., Castonguay A., Rivenson A. Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine. Cancer Res. 1986, 46(2):498-502.
12. Hoffmann D., Hoffmann I. The changing cigarette, 1950-1995. J. Toxicol. Environ. Health 1997, 50:307-364.
13. Hoffmann D., Brunnemann K.D., Prokopczyk B., Djordjevic M.V. Tobacco-specific N-nitrosamines and Areca-derived N-nitrosamines: chemistry, biochemistry, carcinogenicity, and relevance to humans. J. Toxicol. Environ. Health 1994, 41:1-52.
14. Hu Z., Chen X., Zhao Y., Tian T., Jin G., Shu Y., Chen Y., Xu L., Zen K., Zhang C., Shen H. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J. Clin. Oncol. 2010, 28(10):1721-1726.
15. IARC (International Agency for Research on Cancer) Tobacco smoking. IARC Monographs Evaluation Carcinogenic Risks Humans 1986, vol. 38:37-375. IARC Press, Lyon.
16. IARC (International Agency for Research on Cancer) Smokeless tobacco and some tobacco-specific N-Nitrosamines. IARC Monographs Evaluation Carcinogenic Risks Humans 2007, vol. 89:457-463. IARC Press, Lyon.
17. Imam J.S., Buddavarapu K., Lee-Chang J.S., Ganapathy S., Camosy C., Chen Y., Rao M.K. MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers. Oncogene 2010, 29(35):4971-4979.
18. Iorio M.V., Ferracin M., Liu C.G., Veronese A., Spizzo R., Sabbioni S., Magri E., Pedriali M., Fabbri M., Campiglio M., Ménard S., Palazzo J.P., Rosenberg A., Musiani P., Volinia S., Nenci I., Calin G.A., Querzoli P., Negrini M., Croce C.M. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005, 65(16):7065-7070.
19. Jiang Y., Wu Y., Greenlee A.R., Wu J., Han Z., Li X., Zhao Y. miR-106a-mediated malignant transformation of cells induced by anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide. Toxicol. Sci. 2011, 119(1):50-60.
20. Kalscheuer S., Zhang X., Zeng Y., Upadhyaya P. Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 2008, 29(12):2394-2399.
21. Kano M., Seki N., Kikkawa N., Fujimura L., Hoshino I., Akutsu Y., Chiyomaru T., Enokida H., Nakagawa M., Matsubara H. miR-145, miR-133a and miR-133b: tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int. J. Cancer 2010, 127(12):2804-2814.
22. Li Z., Branham W.S., Dial S.L., Wang Y., Guo L., Shi L., Chen T. Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea. BMC Genomics 2010, 11:609. 10.1186/1471-2164-11-609.
23. Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert B.L., Mak R.H., Ferrando A.A., Downing J.R., Jacks T., Horvitz H.R., Golub T.R. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
24. Mascaux C., Laes J.F., Anthoine G., Haller A., Ninane V., Burny A., Sculier J.P. Evolution of microRNA expression during human bronchial squamous carcinogenesis. Eur. Respir. J. 2009, 33(2):352-359.
25. Melkamu T., Zhang X., Tan J., Zeng Y., Kassie F. Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol. Carcinogenesis 2010, 31(2):252-258.
26. Mitchell P.S., Parkin R.K., Kroh E.M., Fritz B.R., Wyman S.K., Pogosova-Agadjanyan E.L., Peterson A., Noteboom J., O'Briant K.C., Allen A., Lin D.W., Urban N., Drescher C.W., Knudsen B.S., Stirewalt D.L., Gentleman R., Vessella R.L., Nelson P.S., Martin D.B., Tewari M. Circulating microRNAs as stable blood-based markers for cancer detection. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(30):10513-10518.
27. Moussay E., Wang K., Cho J.H., van Moer K., Pierson S., Paggetti J., Nazarov P.V., Palissot V., Hood L.E., Berchem G., Galas D.J. MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U. S. A. 2011, 108(16):6573-6578.
28. Murakami Y., Yasuda T., Saigo K., Urashima T., Toyoda H., Okanoue T., Shimotohno K. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 2006, 25(17):2537-2545.
29. Ng E.K., Chong W.W., Jin H., Lam E.K., Shin V.Y., Yu J., Poon T.C., Ng S.S., Sung J.J. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009, 58(10):1375-1381.
30. Nohata N., Hanazawa T., Enokida H., Seki N. microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers. Oncotarget 2012, 3(1):9-21.
31. Porkka K.P., Pfeiffer M.J., Waltering K.K., Vessella R.L., Tammela T.L., Visakorpi T. MicroRNA expression profiling in prostate cancer. Cancer Res. 2007, 67(13):6130-6135.
32. Rabinowits G., Gerçel-Taylor C., Day J.M., Taylor D.D., Kloecker G.H. Exosomal microRNA: a diagnostic marker for lung cancer. Clin. Lung Cancer 2009, 10(1):42-46.
33. Ren X., McHale C.M., Skibola C.F., Smith A.H., Smith M.T., Zhang L. An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis. Environ. Health Perspect. 2011, 119(1):11-19.
34. Schick S.F., Glantz S. Concentrations of the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in sidestream cigarette smoke increase after release into indoor air: results from unpublished tobacco industry research. Cancer Epidemiol. Biomarkers Prev. 2007, 16(8):1547-1553.
35. Song G., Zhang Y., Wang L. MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation. J. Biol. Chem. 2009, 284(46):31921-31927.
36. Szafranska A.E., Davison T.S., John J., Cannon T., Sipos B., Maghnouj A., Labourier E., Hahn S.A. MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 2007, 26(30):4442-4452.
37. Wang K., Zhang S., Marzolf B., Troisch P., Brightman A., Hu Z., Hood L.E., Galas D.J. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(11):4402-4407.
38. Wang Z., Zhao Y., Smith E., Goodall G.J., Drew P.A., Brabletz T., Yang C. Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b. Toxicol. Sci. 2011, 121(1):110-122.
39. Wang X., Ling C., Bai Y., Zhao J. MicroRNA-206 is associated with invasion and metastasis of lung cancer. Anat. Rec. (Hoboken) 2011, 294:88-92.
40. Zhang B., Pan X. RDX induces aberrant expression of microRNAs in mouse brain and liver. Environ. Health Perspect. 2009, 117(2):231-240.
41. Zhao Y., Liu H., Li Y., Wu J., Greenlee A.R., Yang C., Jiang Y. The role of miR-506 in transformed 16HBE cells induced by anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide. Toxicol. Lett. 2011, 205(3):320-326.