Synthesis of cyclic α-aminophosphonates through copper-catalyzed enamine activation

Synthesis (Germany)

Volumn 45, Issue 4, 2013, Pages 463-470

  Han, Junbin ^a   Paton, Robert S ^b   Xu, Bo ^a   Hammond, Gerald B ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

copper; cyclic aminophosphonates; cyclization; enamines; hydroamination; nitrogen heterocycles; phosphorus

Indexed keywords

AMINOPHOSPHONATES; ENAMINES; HYDROAMINATIONS; MECHANISM-BASED; NITROGEN HETEROCYCLES; SIX-MEMBERED RINGS;

CATALYSIS; COPPER; PHOSPHORUS;

CYCLIZATION;

COPPER; DIBENZYL (1 BENZYL 2 METHYLPYRROLIDIN 2 YL)PHOSPHONATE; DIETHYL (1 BENZYL 2 BUTYLPYRROLIDIN 2 YL)PHOSPHONATE; DIETHYL (1 BENZYL 2 METHYLPIPERIDIN 2 YL)PHOSPHONATE; DIETHYL (1 BENZYL 2 METHYLPYRROLIDIN 2 YL)PHOSPHONATE; DIETHYL (1 BENZYL 2 PENTYLPIPERIDIN 2 YL)PHOSPHONATE; DIETHYL (1 BENZYLPYRROLIDIN 2 YL)PHOSPHONATE; DIETHYL (2 BUTYL 1 PHENYLPYRROLIDIN 2 YL)PHOSPHONATE; DIETHYL (2 METHYL 1 PHENYLPYRROLIDIN 2 YL)PHOSPHONATE; DIETHYL (2 PENTYL 1 PHENYLPIPERIDIN 2 YL)PHOSPHONATE; DIETHYL [1 (4 METHOXYPHENYL) 2 PENTYLPIPERIDIN 2 YL]PHOSPHONATE; DIETHYL [2 METHYL 1 (1 PHENYLETHYL)PYRROLIDIN 2 YL]PHOSPHONATE; DIMETHYL (1 BENZYL 2 METHYLPYRROLIDIN 2 YL)PHOSPHONATE; ENAMINE; PHOSPHORAMIDIC ACID; PHOSPHORAMIDIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL STRUCTURE; CYCLIZATION; DEPROTECTION REACTION; NUCLEOPHILICITY; ONE POT SYNTHESIS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT;

EID: 84873569743     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0032-1317984     Document Type: Article

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