11C-acetate and 18F-FDG PET/CT for clinical staging and selection of patients with hepatocellular carcinoma for liver transplantation on the basis of milan criteria: Surgeon's perspective

Journal of Nuclear Medicine

Volumn 54, Issue 2, 2013, Pages 192-200

  Cheung, Tan To ^a,d   Ho, Chi Lai ^b   Lo, Chung Mau ^a,c   Chen, Sirong ^b   Chan, See Ching ^a,c   Kenneth S H Chok, ^a   Fung, James Y ^a   Chan, Albert Chi Yan ^a   Sharr, William ^a   Yau, Thomas ^a   Ronnie T P Poon, ^a,c   Fan, Sheung Tat ^a,c  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HONG KONG SANATORIUM AND HOSPITAL   (Hong Kong)

^c THE UNIVERSITY OF HONG KONG   (Hong Kong)

^d QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

11C acetate; Contrast CT; Liver transplantation; Milan criteria; PET CT

Indexed keywords

ACETIC ACID C 11; FLUORODEOXYGLUCOSE F 18; CARBON; CONTRAST MEDIUM; DIAGNOSTIC AGENT;

ADULT; AGED; CANCER INVASION; CANCER STAGING; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FALSE NEGATIVE RESULT; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; INTERMETHOD COMPARISON; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MALE; METASTASIS; PARTIAL HEPATECTOMY; PATIENT SELECTION; PHYSICIAN ATTITUDE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; SENSITIVITY AND SPECIFICITY; SYNDROME DELINEATION; SYSTEMATIC ERROR; TREATMENT INDICATION; TUMOR VOLUME; ARTICLE; DIAGNOSTIC IMAGING; LIVER TUMOR; METHODOLOGY; MIDDLE AGED; NUCLEAR MEDICINE; ONCOLOGY; POSITRON EMISSION TOMOGRAPHY; REPRODUCIBILITY;

ADULT; AGED; CARBON RADIOISOTOPES; CARCINOMA, HEPATOCELLULAR; CONTRAST MEDIA; DIAGNOSTIC IMAGING; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MALE; MEDICAL ONCOLOGY; MIDDLE AGED; NEOPLASM STAGING; NUCLEAR MEDICINE; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

MLCS; MLOWN;

EID: 84873550587     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.112.107516     Document Type: Review

References (32)

1. Belghiti J, Panis Y, Farges O, Benhamou JP, Fekete F. Intrahepatic recurrence after resection of hepatocellular carcinoma complicating cirrhosis. Ann Surg. 1991;214:114-117.
2. Bruix J, Sherman M, Llovet JM, et al. Clinical management of hepatocellular carcinoma: conclusions of the Barcelona-2000 EASL conference-European Association for the Study of the Liver. J Hepatol. 2001;35:421-430.
3. Llovet JM, Fuster J, Bruix J. The Barcelona approach: diagnosis, staging, and treatment of hepatocellular carcinoma. Liver Transpl. 2004;10:S115-S120.
4. Fan ST. Surgical therapy of hepatocellular carcinoma in the cirrhotic liver. Swiss Surg. 1999;5:107-110.
5. Ng KK, Lo CM, Chan SC, Chok KS, Cheung TT, Fan ST. Liver transplantation for hepatocellular carcinoma: the Hong Kong experience. J Hepatobiliary Pancreat Sci. 2010;17:548-554.
6. Poon RT, Fan ST, Tsang FH, Wong J. Locoregional therapies for hepatocellular carcinoma: a critical review from the surgeon's perspective. Ann Surg. 2002;235: 466-486.
7. Ringe B, Pichlmayr R, Wittekind C, Tusch G. Surgical treatment of hepatocellular carcinoma: experience with liver resection and transplantation in 198 patients. World J Surg. 1991;15:270-285.
8. Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med. 1996; 334:693-699.
9. Yao FY, Bass NM, Nikolai B, et al. Liver transplantation for hepatocellular carcinoma: analysis of survival according to the intention-to-treat principle and dropout from the waiting list. Liver Transpl. 2002;8:873-883.
10. Sangiovanni A, Manini MA, Iavarone M, et al. The diagnostic and economic impact of contrast imaging techniques in the diagnosis of small hepatocellular carcinoma in cirrhosis. Gut. 2010;59:638-644.
11. Yu NC, Chaudhari V, Raman SS, et al. CT and MRI improve detection of hepatocellular carcinoma, compared with ultrasound alone, in patients with cirrhosis. Clin Gastroenterol Hepatol. 2011;9:161-167.
12. Lee DH, Kim SH, Lee JM, et al. Diagnostic performance of multidetector row computed tomography, superparamagnetic iron oxide-enhanced magnetic resonance imaging, and dual-contrast magnetic resonance imaging in predicting the appropriateness of a transplant recipient based on Milan criteria: correlation with histopathological findings. Invest Radiol. 2009;44:311-321.
13. Kim SH, Choi BI, Lee JY, et al. Diagnostic accuracy of multi-/single-detector row CT and contrast-enhanced MRI in the detection of hepatocellular carcinomas meeting the Milan criteria before liver transplantation. Intervirology. 2008;51 (suppl 1):52-60.
14. Macarini L, Marini S, Milillo P, Vinci R, Ettorre GC. Double-contrast MRI (DCMRI) in the study of the cirrhotic liver: utility of administering Gd-DTPA as a complement to examinations in which SPIO liver uptake and distribution alterations (SPIO-LUDA) are present and in the identification and characterisation of focal lesions. Radiol Med (Torino). 2006;111:1087-1102.
15. Ho CL, Chen S, Yeung DW, Cheng TK. Dual-tracer PET/CT imaging in evaluation of metastatic hepatocellular carcinoma. J Nucl Med. 2007;48:902-909.
16. 11C-acetate PET imaging in hepatocellular carcinoma and other liver masses. J Nucl Med. 2003;44:213-221.
17. 18F]FDG PET/CT: a preliminary study. Appl Radiat Isot. 2009;67:1195-1198.
18. Ho CL, Chen S, Cheng TK, Leung YL. PET/CT characteristics of isolated bone metastases in hepatocellular carcinoma. Radiology. 2011;258:515-523.
19. Henderson J, Sherman M, Tavill A, et al. AHPBA/AJCC consensus conference on staging of hepatocellular carcinoma: consensus statement. HBP. 2003;5:243-250.
20. Mazzaferro V, Llovet JM, Miceli R, et al. Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis. Lancet Oncol. 2009;10:35-43.
21. Duffy JP, Vardanian A, Benjamin E, et al. Liver transplantation criteria for hepatocellular carcinoma should be expanded: a 22-year experience with 467 patients at UCLA. Ann Surg. 2007;246:502-509.
22. Lo CM, Fan ST, Liu CL, et al. Ten-year experience with liver transplantation at Queen Mary Hospital: retrospective study. Hong Kong Med J. 2002;8:240-244.
23. Libbrecht L, Bielen D, Verslype C, et al. Focal lesions in cirrhotic explant livers: pathological evaluation and accuracy of pretransplantation imaging examinations. Liver Transpl. 2002;8:749-761.
24. Taouli B, Krinsky GA. Diagnostic imaging of hepatocellular carcinoma in patients with cirrhosis before liver transplantation. Liver Transpl. 2006;12:S1-S7.
25. Forner A, Vilana R, Ayuso C, et al. Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: prospective validation of the noninvasive diagnostic criteria for hepatocellular carcinoma. Hepatology. 2008;47:97-104.
26. Burrel M, Llovet JM, Ayuso C, et al. MRI angiography is superior to helical CT for detection of HCC prior to liver transplantation: an explant correlation. Hepatology. 2003;38:1034-1042.
27. Sotiropoulos GC, Malago M, Molmenti E, et al. Liver transplantation for hepatocellular carcinoma in cirrhosis: is clinical tumor classification before transplantation realistic? Transplantation. 2005;79:483-487.
28. Freeny PC, Grossholz M, Kaakaji K, Schmiedl UP. Significance of hyperattenuating and contrast-enhancing hepatic nodules detected in the cirrhotic liver during arterial phase helical CT in pre-liver transplant patients: radiologic-histopathologic correlation of explanted livers. Abdom Imaging. 2003;28:333-346.
29. Peterson MS, Baron RL, Marsh JW Jr, Oliver JH III, Confer SR, Hunt LE. Pretransplantation surveillance for possible hepatocellular carcinoma in patients with cirrhosis: epidemiology and CT-based tumor detection rate in 430 cases with surgical pathologic correlation. Radiology. 2000;217:743-749.
30. Ronzoni A, Artioli D, Scardina R, et al. Role of MDCT in the diagnosis of hepatocellular carcinoma in patients with cirrhosis undergoing orthotopic liver transplantation. AJR. 2007;189:792-798.
31. 18F FDG PET-CT imaging in hepatocellular carcinoma less than 2 cm. J Nucl Med. 2005;46(suppl):103P.
32. 18F-FDG PET in liver transplantation for hepatocellular carcinoma. J Nucl Med. 2009; 50:682-687.