Relationship Between Toll-like Receptor-4 and mPGES-1 Gene Expression in Local Lesions of Endometriosis Patients

American Journal of Reproductive Immunology

Volumn 69, Issue 3, 2013, Pages 231-239

  Hayashi, Chuyu ^a   Chishima, Fumihisa ^a   Sugitani, Masahiko ^a   Ichikawa, Go ^a   Nakazawa Watanabe, Teine ^a   Sugita, Kenji ^a   Suzuki, Manami ^a   Nemoto, Norimichi ^a   Yamamoto, Tatsuo ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

Endometriosis; Microsomal prostaglandin E synthase; Toll like receptor 4

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 4;

ADULT; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIOSIS; ENDOMETRIUM TUMOR; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INNATE IMMUNITY; LAPAROSCOPIC SURGERY; OVARY CYST; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UTERUS MYOMA;

ADULT; CYCLOOXYGENASE 2; ENDOMETRIOSIS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; IMMUNOHISTOCHEMISTRY; INTRAMOLECULAR OXIDOREDUCTASES; MIDDLE AGED; OVARY; PERITONEUM; RECEPTOR CROSS-TALK; TOLL-LIKE RECEPTOR 4; YOUNG ADULT;

EID: 84873526468     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/aji.12056     Document Type: Article

References (37)

1. Allaire C: Endometriosis and infertility: a review. J Reprod Med 2006; 51:164-168.
2. Lebovic D, Mueller M, Taylo R: Immunobiology of endometriosis. Fertil Steril 2001; 75:1-10.
3. Gazvani R, Templeton A: Peritoneal environment, cytokines and angiogenesis in the pathophysiology of endometriosis. Reproduction 2002; 123:217-226.
4. Osuga Y, Koga K, Hirota Y, Hirata T, Yoshino O, Taketani Y: Lymphocytes in endometriosis. Am J Reprod Immunol 2011; 65:1-10.
5. Vernon MN, Beard JS, Graves K, Wilson EA: Classification of endometriotic implants by morphologic appearance and capacity to synthesize prostaglandin F. Fertil Steril 1986; 46:801-806.
6. Darke TS, O'Brien WF, Ramwell PW, Mets SA: Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F2α in endometriosis. Am J Obstet Gynecol 1981; 140:401-409.
7. Wang D, Dubois RN: Prostaglandins and cancer. Gut 2006; 55:115-122.
8. Ota H, Igarashi S, Sasaki M, Tanaka T: Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis. Hum Reprod 2001; 16:561-566.
9. Chishima F, Hayakawa S, Sugita K, Kinukawa N, Aleemuzzaman S, Nemoto N, Yamamoto T, Honda M: Increased expression of cyclooxygenase-2 in local lesions of endometriosis patients. Am J Reprod Immunol 2002; 48:50-56.
10. Chishima F, Hayakawa S, Yamamoto T, Sugitani M, Karasaki-Suzuki M, Sugita K, Nemoto N: Expression of inducible microsomal prostaglandin E synthase in local lesions of endometriosis patients. Am J Reprod Immunol 2007; 57:218-226.
11. Park JY, Pillinger H, Abramson SB: Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. Clin Immunol 2006; 119:229-240.
12. Iwabe T, Harada T, Terakawa N: Role of cytokines in endometriosis-associated infertility. Gynecol Obstet Invest 2002; 53(Suppl 1):19-25.
13. Gonzalez-Ramos R, Donnez J, Defrere S, Leclercq I, Squifflet J, Lousse JC, Van Langendonckt A: Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis. Mol Hum Reprod 2007; 13:503-509.
14. Akira S: Mammalian Toll-like receptors. Curr Opin Immunol 2003; 15:5-11.
15. Hirata T, Osuga Y, Hirota Y, Koga K, Yoshino O, Harada M, Morimoto C, Yano T, Nishii O, Tsutsumi O, Taketani Y: Evidence for the presence of toll-like receptor 4 system in the human endometrium. J Clin Endocrinol Metab 2005; 90:548-556.
16. Allhorn S, Boeing C, Koch AA, Kimming R, Gashaw I: TLR3 and 4 expression in healthy and diseased human endometrium. Reprod Biol Endocrinol 2008; 6:40.
17. Patni S, Wynen LP, Seager AL, Morgan G, White JO, Thornton CA: Expression and activity of Toll-like receptors 1-9 in the human term placenta and changes associated with labor at term. Biol Reprod 2009; 80:243-248.
18. Seo T, Tatsuguchi A, Shinji S, Yonezawa M, Mitsui K, Tanaka S, Fujimori S, Gudis K, Fukuda Y: Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients. Virchows Arch 2009; 454:667-676.
19. Pujols L, Mullol J, Alobid I, Roca-Ferrer J, Xaubet A, Picado C: Dynamics of COX-2 in nasal mucosa and nasal polyps from aspirin-tolerant and aspirin-intolerant patients with asthma. J Allergy Clin Immunol 2004; 114:814-819.
20. Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK: Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 2002; 415:536-541.
21. Mullen AC, Hutchins AS, High FA, Lee HW, Sykes KJ, Chodosh LA, Reiner SL: Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nat Immunol 2002; 3:652-658.
22. Young SL, Lyddon TD, Jorgenson RL, Misfeldt ML: Expression of Toll-like receptors in human endometrial epithelial cells and cell lines. Am J Reprod Immunol 2004; 52:67-73.
23. Schaefer MS, Fahey JV, Wright JA, Wira CR: Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C). J Immunol 2005; 174:992-1002.
24. Hirata T, Osuga Y, Hamasaki K, Hirota Y, Nose E, Morimoto C, Harada M, Takemura Y, Koga K, Yoshino O, Tajima T, Hasegawa A, Yano T, Taketani Y: Expression of toll-like receptors 2, 3, 4, and 9 genes in the human endometrium during the menstrual cycle. J Reprod Immunol 2007; 74:53-60.
25. Eiserman J, Gast MJ, Pineda J, Odem RR, Collins JL: Tumor necrosis factor in peritoneal fluid of women undergoing laparoscopic surgery. Fertil Steril 1988; 50:573-579.
26. Fakih H, Baggett B, Holtz G, Tsanq KY, Lee JC, Williamson HO: Interleukin-1: a possible role in fertility associated with endometriosis. Fertil Steril 1987; 47:213-217.
27. Chegini N, Rossi MJ, Masterson BJ: Platelet-derived growth factor, epidermal growth factor and EGF and PDGF beta receptors in human endometrial tissue: localization in vitro action. Endocrinology 1992; 130:2373-2385.
28. Khan KN, Kitajima M, Hiraki K, Fujishita A, Sekine I, Ishimaru T, Masuzaki H: Toll-like receptors in innate immunity: role of bacterial endotoxin and toll-like receptor 4 in endometrium and endometriosis. Gynecol Obstet Invest 2009; 68:40-52.
29. Khan KN, Kitajima M, Hiraki K, Yamaguchi N, Katamine S, Matsuyama T, Nakashima M, Fujishita A, Ishimaru T, Masuzaki H: Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis. Fertil Steril 2010; 94:2860-2863.
30. Kovalenko VL, Voropaeva EE, Kozachkov EL, Kozachkova EA: Endometrial pathomorphology in bacterial vaginosis associated with chronic endometriosis. Arkh Patol 2008; 70:6-8.
31. Kavoussi SK, Pearlman MD, Burke WM, Lebovic DI: Endometrioma complicated by tubo-ovarian abscess in a woman with bacterial vaginosis. Infect Dis Obstet Gynecol 2006; 2006:84140.
32. Ishikawa TO, Jain N, Herschman HR: Feedback regulation of cyclooxygenase-2 transcription ex vivo and in vivo. Biochem Biophys Res Commun 2009; 378:534-538.
33. Olivares C, Bilotas M, Buquet R, Borghi M, Sueldo C, Tesone M, Meresman G: Effects of a selective cyclooxygenase-2 inhibitor on endometrial epithelial cells from patients with endometriosis. Hum Reprod 2008; 23:2701-2708.
34. Herath S, Fischer DP, Werling D, Williams EJ, Lilly ST, Dobson H, Bryant CE, Shelden IM: Expression and function of Toll-like receptor 4 in the endometrial cells of the uterus. Endocrinology 2005; 147:562-570.
35. Latha M, Vaidya S, Movva S, Chava S, Govindan S, Govatati S, Banoori M, Hasan Q, Kodati VL: Molecular pathogenesis of endometriosis; Toll-like receptor-4 A896G (D299G) polymorphism: a novel explanation. Genet Test Mol Biomarkers 2010; 15:181-184.
36. Shiraishi H, Yoshida H, Saki K, Miura Y, Watanabe S, Ishizaki T, Hashimoto M, Takaesu G, Kobayashi T, Yoshimura A: Prostaglandin E2 is a major soluble factor produced by stromal cells for preventing inflammatory cytokine production from dendritic cells. Int Immunol 2008; 20:1219-1229.
37. Yao C, Sakata D, Esaki Y, Li Y, Matsuoka T, Kuroiwa K, Sugimoto Y, Narumiya S: Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion. Nat Med 2009; 15:633-640.