Pulmonary hypertension is associated with higher mortality in cystic fibrosis patients awaiting lung transplantation

Journal of Cardiovascular Surgery

Volumn 53, Issue 6, 2012, Pages 817-820

  Venuta, F ^a   Tonelli, A R ^b   Anile, M ^a   Diso, D ^a   De Giacomo, T ^a   Ruberto, F ^a   Russo, E ^a   Rolla, M ^a   Quattrucci, S ^a   Rendina, E A ^a   Li Phd, N ^c   Coloni, G F ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Cystic fibrosis; Hypertension, pulmonary; Lung transplantation

Indexed keywords

ADULT; ARTICLE; CYSTIC FIBROSIS; FEMALE; HEART CATHETERIZATION; HUMAN; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; OUTCOME ASSESSMENT; PREVALENCE; PULMONARY HYPERTENSION; VASCULAR RESISTANCE; HOSPITAL ADMISSION; RETROSPECTIVE STUDY; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE;

ADULT; CYSTIC FIBROSIS; FEMALE; HUMANS; HYPERTENSION, PULMONARY; LUNG TRANSPLANTATION; MALE; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE; WAITING LISTS; YOUNG ADULT;

EID: 84873510021     PISSN: 00219509     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Badesch DB, Champion HC, Sanchez MA, Hoeper MM, Loyd JE, Manes A et al. Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol 2009;54:S55-66.
2. Tonelli AR, Lodhi S, Carrie R, Olufemi AA, Fernandez-Bussy S, Mubarak K et al. Incidence and factors associated with pulmonary hypertension in patients with advanced lung disease evaluated for lung transplantation. Chest 2009;136:61s.
3. Ionescu AA, Ionescu AA, Payne N, Obieta-Fresnedo I, Fraser AG, Shale DJ. Subclinical right ventricular dysfunction in cystic fibrosis. A study using tissue Doppler echocardiography. Am J Respir Crit Care Med 2001;163:1212-8. (Pubitemid 32378462)
4. Stern RC, Borkat G, Hirschfeld SS, Boat TF, Matthews LW, Liebman J et al. Heart failure in cystic fibrosis. Treatment and prognosis of cor pulmonale with failure of the right side of the heart. Am J Dis Child. 1980;134:267-72. (Pubitemid 10133743)
5. Simonneau G, Robbins IM, Beghetti M, Channick RN, Delcroix M, Denton CP et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2009;54:S43-54.6
6. Goldring RM, Fishman AP, Turino GM, Cohen HI, Denning CR, Andersen DH. Pulmonary hypertension and cor pulmonale in cystic fibrosis of the pancreas. J Pediatr 1964;65:501-24.
7. Burghuber OC, Salzer-Muhar U, Bergmann H, Götz M. Right ventricular performance and pulmonary haemodynamics in adolescent and adult patients with cystic fibrosis. Eur J Pediatr 1988;148:187-92. (Pubitemid 19016133)
8. Venuta F, Rendina EA, Rocca GD, De Giacomo T, Pugliese F, Ciccone AM et al. Pulmonary hemodynamics contribute to indicate priority for lung transplantation in patients with cystic fibrosis. J Thorac Cardiovasc Surg 2000;119:682-9. (Pubitemid 30395465)
9. Tonelli AR, Fernandez-Bussy S, Lodhi S, Akindipe OA, Carrie RD, Hamilton K et al. Prevalence of pulmonary hypertension in end-stage cystic fibrosis and correlation with survival. J Heart Lung Transplant 2010;29:865-72.
10. Vizza CD, Yusen RD, Lynch JP, Fedele F, Patterson GA, Trulock EP. Outcome of patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med 2000;162:819-25.
11. Mannarino S, Salice P, Constantini D. Right and left ventricular involvement in patients with cystic fibrosis and respiratory failure. Pediatr Pulmonol 2000;S20:294.
12. Belkin RA, Henig NR, Singer LG, Chaparro C, Rubenstein RC, Xie S et al. Risk factors for death of patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med 2006;173:659-66. (Pubitemid 43363808)
13. Rovedder PM, Ziegler B, Pasin LR, Rampon G, Pinotti AF, de Tarso Roth Dalcin P et al. Doppler echocardiogram, oxygen saturation and submaximum capacity of exercise in patients with cystic fibrosis. J Cyst Fibros 2007;6:277-83. (Pubitemid 46991562)
14. Rovedder PM, Ziegler B, Pinotti AF, Menna Barreto SS, Dalcin T. Prevalence of pulmonary hypertension evaluated by Doppler echocardiography in a population of adolescent and adult patients with cystic fibrosis. J Bras Pneumol 2008;34:83-90.
15. Francis PW, Muller NL, Gurwitz D, Milligan DW, Levison H, Bryan AC. Hemoglobin desaturation: its occurrence during sleep in patients with cystic fibrosis. Am J Dis Child 1980;134:734-40. (Pubitemid 10046502)
16. Fauroux B, Hart N, Belfar S, Boulé M, Tillous-Borde I, Bonnet D et al. Burkholdería cepacia is associated with pulmonary hypertension and increased mortality among cystic fibrosis patients. J Clin Microbiol 2004;42:5537-41.
17. Kerem E, Reisman J, Corey M, Canny GJ, Levison H. Prediction of mortality in patients with cystic fibrosis. N Engl J Med. 1992;326:1187-91.
18. Selimovic N, Andersson B, Bergh CH, Mårtensson G, Nilsson F, Bech-Hanssen O et al. Pulmonary hemodynamics as predictors of mortality in patients awaiting lung transplantation. Transpl Int 2008;21:314-9. (Pubitemid 351348005)
19. Siassi B, Moss AJ, Dooley RR. Clinical recognition of cor pulmonale in cystic fibrosis. J Pediatr 1971;78:794-805.