-
1
-
-
34447104602
-
Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators
-
Yong VW, Zabad RK, Agrawal S, Goncalves Dasilva A, Metz LM, (2007) Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators. J Neurol Sci 259: 79-84.
-
(2007)
J Neurol Sci
, vol.259
, pp. 79-84
-
-
Yong, V.W.1
Zabad, R.K.2
Agrawal, S.3
Goncalves Dasilva, A.4
Metz, L.M.5
-
2
-
-
0033613075
-
A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain
-
Shields DC, Schaecher KE, Saido TC, Banik NL, (1999a) A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain. Proc Natl Acad Sci U S A 96: 11486-11491.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11486-11491
-
-
Shields, D.C.1
Schaecher, K.E.2
Saido, T.C.3
Banik, N.L.4
-
3
-
-
0034774402
-
Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage
-
Gveric D, Hanemaaijer R, Newcombe J, van Lent NA, Sier CF, et al. (2001) Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage. Brain 124: 1978-1988.
-
(2001)
Brain
, vol.124
, pp. 1978-1988
-
-
Gveric, D.1
Hanemaaijer, R.2
Newcombe, J.3
van Lent, N.A.4
Sier, C.F.5
-
4
-
-
33750621156
-
A novel calpain inhibitor for the treatment of acute experimental autoimmune encephalomyelitis
-
Hassen GW, Feliberti J, Kesner L, Stracher A, Mokhtarian F, (2006) A novel calpain inhibitor for the treatment of acute experimental autoimmune encephalomyelitis. J Neuroimmunol 180: 135-146.
-
(2006)
J Neuroimmunol
, vol.180
, pp. 135-146
-
-
Hassen, G.W.1
Feliberti, J.2
Kesner, L.3
Stracher, A.4
Mokhtarian, F.5
-
5
-
-
0032510779
-
Increased calpain expression in activated glial and inflammatory cells in experimental allergic encephalomyelitis
-
Shields DC, Tyor WR, Deibler GE, Hogan EL, Banik NL, (1998) Increased calpain expression in activated glial and inflammatory cells in experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A 95: 5768-5772.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5768-5772
-
-
Shields, D.C.1
Tyor, W.R.2
Deibler, G.E.3
Hogan, E.L.4
Banik, N.L.5
-
6
-
-
0029094262
-
Calpain secreted by activated human lymphoid cells degrades myelin
-
Deshpande RV, Goust JM, Hogan EL, Banik NL, (1995) Calpain secreted by activated human lymphoid cells degrades myelin. J Neurosci Res 42: 259-265.
-
(1995)
J Neurosci Res
, vol.42
, pp. 259-265
-
-
Deshpande, R.V.1
Goust, J.M.2
Hogan, E.L.3
Banik, N.L.4
-
7
-
-
33645764948
-
Protein co-expression with axonal injury in multiple sclerosis plaques
-
Diaz-Sanchez M, Williams K, DeLuca GC, Esiri MM, (2006) Protein co-expression with axonal injury in multiple sclerosis plaques. Acta Neuropathol 111: 289-299.
-
(2006)
Acta Neuropathol
, vol.111
, pp. 289-299
-
-
Diaz-Sanchez, M.1
Williams, K.2
DeLuca, G.C.3
Esiri, M.M.4
-
8
-
-
0036343839
-
Calpain expression and infiltration of activated T cells in experimental allergic encephalomyelitis over time: increased calpain activity begins with onset of disease
-
Schaecher K, Rocchini A, Dinkins J, Matzelle DD, Banik NL, (2002) Calpain expression and infiltration of activated T cells in experimental allergic encephalomyelitis over time: increased calpain activity begins with onset of disease. J Neuroimmunol 129: 1-9.
-
(2002)
J Neuroimmunol
, vol.129
, pp. 1-9
-
-
Schaecher, K.1
Rocchini, A.2
Dinkins, J.3
Matzelle, D.D.4
Banik, N.L.5
-
9
-
-
0033106023
-
Pathophysiological role of calpain in experimental demyelination
-
Shields DC, Banik NL, (1999) Pathophysiological role of calpain in experimental demyelination. J Neurosci Res 55: 533-541.
-
(1999)
J Neurosci Res
, vol.55
, pp. 533-541
-
-
Shields, D.C.1
Banik, N.L.2
-
10
-
-
0029089779
-
Calpain as a novel target for treating acute neurodegenerative disorders
-
Bartus RT, Elliott PJ, Hayward NJ, Dean RL, Harbeson S, et al. (1995) Calpain as a novel target for treating acute neurodegenerative disorders. Neurol Res 17: 249-258.
-
(1995)
Neurol Res
, vol.17
, pp. 249-258
-
-
Bartus, R.T.1
Elliott, P.J.2
Hayward, N.J.3
Dean, R.L.4
Harbeson, S.5
-
11
-
-
0036737795
-
Matrix metalloproteinases in neuroinflammation
-
Rosenberg GA, (2002) Matrix metalloproteinases in neuroinflammation. Glia 39: 279-291.
-
(2002)
Glia
, vol.39
, pp. 279-291
-
-
Rosenberg, G.A.1
-
12
-
-
0344420053
-
Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis
-
Opdenakker G, Nelissen I, Van Damme J, (2003) Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis. Lancet Neurol 2: 747-756.
-
(2003)
Lancet Neurol
, vol.2
, pp. 747-756
-
-
Opdenakker, G.1
Nelissen, I.2
Van Damme, J.3
-
13
-
-
0037882437
-
Gelatinase B producing cells in multiple sclerosis lesions
-
Steinman L, Gijbels K (1994) Gelatinase B producing cells in multiple sclerosis lesions. J Cell Biochem Suppl. 18D: 143.
-
(1994)
J Cell Biochem Suppl
, vol.18 D
, pp. 143
-
-
Steinman, L.1
Gijbels, K.2
-
14
-
-
0026442957
-
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders
-
Gijbels K, Masure S, Carton H, Opdenakker G, (1992) Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J Neuroimmunol 41: 29-34.
-
(1992)
J Neuroimmunol
, vol.41
, pp. 29-34
-
-
Gijbels, K.1
Masure, S.2
Carton, H.3
Opdenakker, G.4
-
15
-
-
0035989120
-
Intrathecal synthesis of matrix metalloproteinase-9 in patients with multiple sclerosis: implication for pathogenesis
-
Liuzzi GM, Trojano M, Fanelli M, Avolio C, Fasano A, et al. (2002) Intrathecal synthesis of matrix metalloproteinase-9 in patients with multiple sclerosis: implication for pathogenesis. Mult Scler 8: 222-228.
-
(2002)
Mult Scler
, vol.8
, pp. 222-228
-
-
Liuzzi, G.M.1
Trojano, M.2
Fanelli, M.3
Avolio, C.4
Fasano, A.5
-
16
-
-
0029907622
-
The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution
-
Cuzner ML, Gveric D, Strand C, Loughlin AJ, Paemen L, et al. (1996) The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution. J Neuropathol Exp Neurol 55: 1194-1204.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 1194-1204
-
-
Cuzner, M.L.1
Gveric, D.2
Strand, C.3
Loughlin, A.J.4
Paemen, L.5
-
17
-
-
0027169231
-
Leukocyte gelatinase B cleavage releases encephalitogens from human myelin basic protein
-
Proost P, Van Damme J, Opdenakker G, (1993) Leukocyte gelatinase B cleavage releases encephalitogens from human myelin basic protein. Biochem Biophys Res Commun 192: 1175-1181.
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 1175-1181
-
-
Proost, P.1
Van Damme, J.2
Opdenakker, G.3
-
18
-
-
0029586166
-
Matrix metalloproteinases degrade myelin basic protein
-
Chandler S, Coates R, Gearing A, Lury J, Wells G, et al. (1995) Matrix metalloproteinases degrade myelin basic protein. Neurosci Lett 201: 223-226.
-
(1995)
Neurosci Lett
, vol.201
, pp. 223-226
-
-
Chandler, S.1
Coates, R.2
Gearing, A.3
Lury, J.4
Wells, G.5
-
19
-
-
0035478029
-
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
-
Asahi M, Wang X, Mori T, Sumii T, Jung JC, et al. (2001) Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 21: 7724-7732.
-
(2001)
J Neurosci
, vol.21
, pp. 7724-7732
-
-
Asahi, M.1
Wang, X.2
Mori, T.3
Sumii, T.4
Jung, J.C.5
-
20
-
-
0032716573
-
Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-1b treatment in relapsing-remitting MS
-
Trojano M, Avolio C, Liuzzi GM, Ruggieri M, Defazio G, et al. (1999) Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-1b treatment in relapsing-remitting MS. Neurology 53: 1402-1408.
-
(1999)
Neurology
, vol.53
, pp. 1402-1408
-
-
Trojano, M.1
Avolio, C.2
Liuzzi, G.M.3
Ruggieri, M.4
Defazio, G.5
-
21
-
-
0037435501
-
IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS
-
Waubant E, Goodkin D, Bostrom A, Bacchetti P, Hietpas J, et al. (2003) IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS. Neurology 60: 52-57.
-
(2003)
Neurology
, vol.60
, pp. 52-57
-
-
Waubant, E.1
Goodkin, D.2
Bostrom, A.3
Bacchetti, P.4
Hietpas, J.5
-
22
-
-
10744229980
-
Neutralizing antibodies against IFN-beta in multiple sclerosis: antagonization of IFN-beta mediated suppression of MMPs
-
Gilli F, Bertolotto A, Sala A, Hoffmann F, Capobianco M, et al. (2004) Neutralizing antibodies against IFN-beta in multiple sclerosis: antagonization of IFN-beta mediated suppression of MMPs. Brain 127: 259-268.
-
(2004)
Brain
, vol.127
, pp. 259-268
-
-
Gilli, F.1
Bertolotto, A.2
Sala, A.3
Hoffmann, F.4
Capobianco, M.5
-
23
-
-
0024955057
-
Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplieded method
-
Nakajima K, Hamanoue M, Shimojo M, Takei N, Kohsaka S, (1989) Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplieded method. Biomed Res 10: 411-423.
-
(1989)
Biomed Res
, vol.10
, pp. 411-423
-
-
Nakajima, K.1
Hamanoue, M.2
Shimojo, M.3
Takei, N.4
Kohsaka, S.5
-
24
-
-
0019313317
-
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
-
McCarthy KD, de Vellis J, (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85: 890-902.
-
(1980)
J Cell Biol
, vol.85
, pp. 890-902
-
-
McCarthy, K.D.1
de Vellis, J.2
-
25
-
-
0015264390
-
Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species
-
Deibler GE, Martenson RE, Kies MW, (1972) Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep Biochem 2: 139-165.
-
(1972)
Prep Biochem
, vol.2
, pp. 139-165
-
-
Deibler, G.E.1
Martenson, R.E.2
Kies, M.W.3
-
26
-
-
0036570539
-
Casein zymography of calpains using a 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid-imidazole buffer
-
Croall DE, Moffett K, Hatch H, (2002) Casein zymography of calpains using a 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid-imidazole buffer. Anal Biochem 304: 129-132.
-
(2002)
Anal Biochem
, vol.304
, pp. 129-132
-
-
Croall, D.E.1
Moffett, K.2
Hatch, H.3
-
27
-
-
0020198680
-
Electrophoresis buffers for polyacrylamide gels at various pH
-
McLellan T, (1982) Electrophoresis buffers for polyacrylamide gels at various pH. Anal Biochem 126: 94-99.
-
(1982)
Anal Biochem
, vol.126
, pp. 94-99
-
-
McLellan, T.1
-
28
-
-
3042694846
-
Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment
-
Liuzzi GM, Latronico T, Fasano A, Carlone G, Riccio P, (2004) Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment. Mult Scler 10: 290-297.
-
(2004)
Mult Scler
, vol.10
, pp. 290-297
-
-
Liuzzi, G.M.1
Latronico, T.2
Fasano, A.3
Carlone, G.4
Riccio, P.5
-
29
-
-
0026558127
-
TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase
-
Rosenberg GA, Kornfeld M, Estrada E, Kelley RO, Liotta LA, et al. (1992) TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase. Brain Res 576: 203-207.
-
(1992)
Brain Res
, vol.576
, pp. 203-207
-
-
Rosenberg, G.A.1
Kornfeld, M.2
Estrada, E.3
Kelley, R.O.4
Liotta, L.A.5
-
30
-
-
0029417152
-
TNF-alpha- and IFN-gamma-mediated signal transduction pathways: effects on glial cell gene expression and function
-
Benveniste EN, (1995) TNF-alpha- and IFN-gamma-mediated signal transduction pathways: effects on glial cell gene expression and function. Faseb J 9: 1577-1584.
-
(1995)
Faseb J
, vol.9
, pp. 1577-1584
-
-
Benveniste, E.N.1
-
31
-
-
0029041446
-
T-cell gelatinases mediate basement membrane transmigration in vitro
-
Leppert D, Waubant E, Galardy R, Bunnett N, Hauser SL, (1995) T-cell gelatinases mediate basement membrane transmigration in vitro. J Immunol 154: 4379-4389.
-
(1995)
J Immunol
, vol.154
, pp. 4379-4389
-
-
Leppert, D.1
Waubant, E.2
Galardy, R.3
Bunnett, N.4
Hauser, S.L.5
-
32
-
-
0028876328
-
Release of myelin basic protein-degrading proteolytic activity from microglia and macrophages after infection with Theiler's murine encephalomyelitis virus: comparison between susceptible and resistant mice
-
Liuzzi GM, Riccio P, Dal Canto MC, (1995) Release of myelin basic protein-degrading proteolytic activity from microglia and macrophages after infection with Theiler's murine encephalomyelitis virus: comparison between susceptible and resistant mice. J Neuroimmunol 62: 91-102.
-
(1995)
J Neuroimmunol
, vol.62
, pp. 91-102
-
-
Liuzzi, G.M.1
Riccio, P.2
Dal Canto, M.C.3
-
33
-
-
0742305822
-
Anti-HIV drugs decrease the expression of matrix metalloproteinases in astrocytes and microglia
-
Liuzzi GM, Mastroianni CM, Latronico T, Mengoni F, Fasano A, et al. (2004b) Anti-HIV drugs decrease the expression of matrix metalloproteinases in astrocytes and microglia. Brain 127: 398-407.
-
(2004)
Brain
, vol.127
, pp. 398-407
-
-
Liuzzi, G.M.1
Mastroianni, C.M.2
Latronico, T.3
Mengoni, F.4
Fasano, A.5
-
34
-
-
82955203465
-
Probing cytokines, chemokines and matrix metalloproteinases towards better immunotherapies of multiple sclerosis
-
Opdenakker G, Van Damme J, (2011) Probing cytokines, chemokines and matrix metalloproteinases towards better immunotherapies of multiple sclerosis. Cytokine Growth Factor Rev 22: 359-65.
-
(2011)
Cytokine Growth Factor Rev
, vol.22
, pp. 359-365
-
-
Opdenakker, G.1
Van Damme, J.2
-
35
-
-
69949116702
-
Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells
-
Guyton MK, Brahmachari S, Das A, Samantaray S, Inoue J, et al. (2009) Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells. J Neurochem 110: 1895-1907.
-
(2009)
J Neurochem
, vol.110
, pp. 1895-1907
-
-
Guyton, M.K.1
Brahmachari, S.2
Das, A.3
Samantaray, S.4
Inoue, J.5
-
36
-
-
77955355417
-
Calpeptin attenuated inflammation, cell death, and axonal damage in animal model of multiple sclerosis
-
Guyton MK, Das A, Samantaray S, Wallace GC 4th, Butler JT, et al (2010) Calpeptin attenuated inflammation, cell death, and axonal damage in animal model of multiple sclerosis. J Neurosci Res 88: 2398-2408.
-
(2010)
J Neurosci Res
, vol.88
, pp. 2398-2408
-
-
Guyton, M.K.1
Das, A.2
Samantaray, S.3
Wallace 4th, G.C.4
Butler, J.T.5
-
37
-
-
0030717692
-
Tissue inhibitors of metalloproteinases: structure, regulation and biological functions
-
Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP, (1997) Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 74: 111-122.
-
(1997)
Eur J Cell Biol
, vol.74
, pp. 111-122
-
-
Gomez, D.E.1
Alonso, D.F.2
Yoshiji, H.3
Thorgeirsson, U.P.4
-
38
-
-
0034834709
-
Human monocyte-derived dendritic cells produce bioactive gelatinase B: inhibition by IFN-beta
-
Bartholomé EJ, Van Aelst I, Koyen E, Kiss R, Willems F, et al. (2001) Human monocyte-derived dendritic cells produce bioactive gelatinase B: inhibition by IFN-beta. J Interferon Cytokine Res. 21: 495-501.
-
(2001)
J Interferon Cytokine Res
, vol.21
, pp. 495-501
-
-
Bartholomé, E.J.1
Van Aelst, I.2
Koyen, E.3
Kiss, R.4
Willems, F.5
-
39
-
-
0032086011
-
Case report: DNA fragmentation in glial cells in a cerebral biopsy from a multiple sclerosis patient
-
Benjelloun N, Ménard A, Charriaut-Marlangue C, Mokhtari K, Perron H, et al. (1998) Case report: DNA fragmentation in glial cells in a cerebral biopsy from a multiple sclerosis patient. Cell Mol Biol. 44: 579-83.
-
(1998)
Cell Mol Biol
, vol.44
, pp. 579-583
-
-
Benjelloun, N.1
Ménard, A.2
Charriaut-Marlangue, C.3
Mokhtari, K.4
Perron, H.5
-
40
-
-
0029960673
-
Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain
-
Dowling P, Shang G, Raval S, Menonna J, Cook S, et al. (1996) Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J Exp Med. 184: 1513-8.
-
(1996)
J Exp Med
, vol.184
, pp. 1513-1518
-
-
Dowling, P.1
Shang, G.2
Raval, S.3
Menonna, J.4
Cook, S.5
-
41
-
-
23744449849
-
Upregulation of calpain correlates with increased neurodegeneration in acute experimental auto-immune encephalomyelitis
-
Guyton MK, Wingrave JM, Yallapragada AV, Wilford GG, Sribnick EA, et al. (2005) Upregulation of calpain correlates with increased neurodegeneration in acute experimental auto-immune encephalomyelitis. J Neurosci Res 81: 53-61.
-
(2005)
J Neurosci Res
, vol.81
, pp. 53-61
-
-
Guyton, M.K.1
Wingrave, J.M.2
Yallapragada, A.V.3
Wilford, G.G.4
Sribnick, E.A.5
-
42
-
-
0141616458
-
Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia
-
Suryadevara R, Holter S, Borgmann K, Persidsky R, Labenz-Zink C, et al. (2003) Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia. Glia 44: 47-56.
-
(2003)
Glia
, vol.44
, pp. 47-56
-
-
Suryadevara, R.1
Holter, S.2
Borgmann, K.3
Persidsky, R.4
Labenz-Zink, C.5
-
43
-
-
0035986081
-
Matrix metalloproteinase-9 and tissue inhibitors of matrix metalloproteinase-1 in plasma of patients co-infected with HCV and HIV
-
Mastroianni CM, Liuzzi GM, D'Ettorre G, Lichtner M, Forcina G, et al. (2002) Matrix metalloproteinase-9 and tissue inhibitors of matrix metalloproteinase-1 in plasma of patients co-infected with HCV and HIV. HIV Clin Trials 3: 310-315.
-
(2002)
HIV Clin Trials
, vol.3
, pp. 310-315
-
-
Mastroianni, C.M.1
Liuzzi, G.M.2
D'Ettorre, G.3
Lichtner, M.4
Forcina, G.5
|