-
1
-
-
1542377277
-
Inactivation of hCDC4 can cause chromosomal instability
-
Rajagopalan H, Jallepalli PV, Rago C, Velculescu VE, Kinzler KW, Vogelstein B, and Lengauer C (2004). Inactivation of hCDC4 can cause chromosomal instability. Nature 428, 77-81.
-
(2004)
Nature
, vol.428
, pp. 77-81
-
-
Rajagopalan, H.1
Jallepalli, P.V.2
Rago, C.3
Velculescu, V.E.4
Kinzler, K.W.5
Vogelstein, B.6
Lengauer, C.7
-
2
-
-
9244263076
-
Aneuploidy and cancer
-
Rajagopalan H and Lengauer C (2004). Aneuploidy and cancer. Nature 432, 338-341.
-
(2004)
Nature
, vol.432
, pp. 338-341
-
-
Rajagopalan, H.1
Lengauer, C.2
-
3
-
-
33846168450
-
Genomic mechanisms and measurement of structural and numerical instability in cancer cells
-
Bayani J, Selvarajah S, Maire G, Vukovic B, Al-Romaih K, Zielenska M, and Squire JA (2007). Genomic mechanisms and measurement of structural and numerical instability in cancer cells. Semin Cancer Biol 17, 5-18.
-
(2007)
Semin Cancer Biol
, vol.17
, pp. 5-18
-
-
Bayani, J.1
Selvarajah, S.2
Maire, G.3
Vukovic, B.4
Al-Romaih, K.5
Zielenska, M.6
Squire, J.A.7
-
4
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, et al. (2005). Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434, 907-913.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
Ditullio Jr., R.A.8
Kastrinakis, N.G.9
Levy, B.10
-
5
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell PC (1976). The clonal evolution of tumor cell populations. Science 4260, 23-28.
-
(1976)
Science
, vol.4260
, pp. 23-28
-
-
Nowell, P.C.1
-
6
-
-
0026781490
-
The integration of molecular genetics into cancer management
-
Weinberg RA (1992). The integration of molecular genetics into cancer management. Cancer 70, 1653-1658.
-
(1992)
Cancer
, vol.70
, pp. 1653-1658
-
-
Weinberg, R.A.1
-
7
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B and Kinzler KW (2004). Cancer genes and the pathways they control. Nat Med 10, 789-799.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
8
-
-
14644398628
-
Chromosome instability in neoplasia: Chaotic roots to continuous growth
-
Gagos S and Irminger-Finger I (2005). Chromosome instability in neoplasia: chaotic roots to continuous growth. Int J Biochem Cell Biol 37, 1014-1033.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 1014-1033
-
-
Gagos, S.1
Irminger-Finger, I.2
-
9
-
-
84856013431
-
Clonal evolution in cancer
-
Greaves M and Maley CC (2012). Clonal evolution in cancer. Nature 481, 306-313.
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
10
-
-
0347762556
-
From polyploidy to aneuploidy, genome instability and cancer
-
Storchova Z and Pellman D (2004). From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol 5, 45-54.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 45-54
-
-
Storchova, Z.1
Pellman, D.2
-
11
-
-
70349912085
-
Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: Implications for drug resistance and in vitro drug screening models
-
Sabisz M and Skladanowski A (2009). Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: implications for drug resistance and in vitro drug screening models. Cell Cycle 8, 3208-3217.
-
(2009)
Cell Cycle
, vol.8
, pp. 3208-3217
-
-
Sabisz, M.1
Skladanowski, A.2
-
13
-
-
77957764817
-
MOS, aneuploidy and the ploidy cycle of cancer cells. Review
-
Erenpreisa J and Cragg SM (2010). MOS, aneuploidy and the ploidy cycle of cancer cells. Review. Oncogene 29, 5447-5451.
-
(2010)
Oncogene
, vol.29
, pp. 5447-5451
-
-
Erenpreisa, J.1
Cragg, S.M.2
-
15
-
-
19844382620
-
Senescence and immortalization: Role of telomeres and telomerase
-
Shay JW and Wright WE (2005). Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 26, 867-874.
-
(2005)
Carcinogenesis
, vol.26
, pp. 867-874
-
-
Shay, J.W.1
Wright, W.E.2
-
16
-
-
0035822079
-
Defects in mismatch repair promote telomerase-independent proliferation
-
Rizki A and Lundblad V (2001). Defects in mismatch repair promote telomerase-independent proliferation. Nature 411, 713-716.
-
(2001)
Nature
, vol.411
, pp. 713-716
-
-
Rizki, A.1
Lundblad, V.2
-
17
-
-
0034733606
-
Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang
-
Huffman EK, Levene DS, Tesmer MV, Shay WJ, and Wright EW (2000). Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang. J Biol Chem 275, 19719-19722.
-
(2000)
J Biol Chem
, vol.275
, pp. 19719-19722
-
-
Huffman, E.K.1
Levene, D.S.2
Tesmer, M.V.3
Shay, W.J.4
Wright, E.W.5
-
18
-
-
3342972121
-
Does a sentinel or a subset of short telomeres determine replicative senescence?
-
Zou Y, Sfeir A, Gryaznov SM, Shay JW, and Wright WE (2004). Does a sentinel or a subset of short telomeres determine replicative senescence? Mol Biol Cell 15, 3709-3718.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 3709-3718
-
-
Zou, Y.1
Sfeir, A.2
Gryaznov, S.M.3
Shay, J.W.4
Wright, W.E.5
-
19
-
-
17144410403
-
The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line
-
Sabatier L, Ricoul M, Pottier G, and Murnane JP (2005). The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line. Mol Cancer Res 3, 139-150.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 139-150
-
-
Sabatier, L.1
Ricoul, M.2
Pottier, G.3
Murnane, J.P.4
-
20
-
-
0028981143
-
Time, telomeres and tumours: Is cellular senescence more than an anticancer mechanism?
-
Wright WE and Shay JW (1995). Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism? Trends Cell Biol 5, 293-297.
-
(1995)
Trends Cell Biol
, vol.5
, pp. 293-297
-
-
Wright, W.E.1
Shay, J.W.2
-
21
-
-
0035253719
-
Cellular senescence as a tumor-protection mechanism: The essential role of counting
-
Wright WE and Shay JW (2001). Cellular senescence as a tumor-protection mechanism: the essential role of counting. Curr Opin Genet Dev 11, 98-103.
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 98-103
-
-
Wright, W.E.1
Shay, J.W.2
-
22
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis TD, Gorgoulis VG, and Bartek J (2008). An oncogene-induced DNA damage model for cancer development. Science 319, 1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
23
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, and Shay JW (1994). Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
24
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW and Bacchetti S (1997). A survey of telomerase activity in human cancer. Eur J Cancer 33, 787-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
25
-
-
27744527486
-
The first molecular details of ALT in human tumor cells
-
Muntoni A and Reddel RR (2005). The first molecular details of ALT in human tumor cells. Hum Mol Genet 14, 191-196.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 191-196
-
-
Muntoni, A.1
Reddel, R.R.2
-
26
-
-
78650662899
-
Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells
-
Nabetani A and Ishikawa F (2011). Alternative lengthening of telomeres pathway: recombination-mediated telomere maintenance mechanism in human cells. J Biochem 149, 5-14.
-
(2011)
J Biochem
, vol.149
, pp. 5-14
-
-
Nabetani, A.1
Ishikawa, F.2
-
27
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, and Greider CW (1997). Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91, 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
Depinho, R.A.6
Greider, C.W.7
-
28
-
-
12944329959
-
Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity
-
Gisselsson D, Pettersson L, Höglund M, Heidenblad M, Gorunova L, Wiegant J, Mertens F, Dal Cin P, Mitelman F, and Mandahl N (2000). Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity. Proc Natl Acad Sci USA 97, 5357-5362.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5357-5362
-
-
Gisselsson, D.1
Pettersson, L.2
Höglund, M.3
Heidenblad, M.4
Gorunova, L.5
Wiegant, J.6
Mertens, F.7
Dal Cin, P.8
Mitelman, F.9
Mandahl, N.10
-
29
-
-
1242292420
-
Genomic instability and colon cancer
-
Grady WM (2004). Genomic instability and colon cancer. Cancer Metastasis Rev 23, 11-27.
-
(2004)
Cancer Metastasis Rev
, vol.23
, pp. 11-27
-
-
Grady, W.M.1
-
30
-
-
19844366700
-
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer
-
Gorringe LK, Chin S, Pharoah P, Staines MJ, Oliveira C, Edwards PA, and Caldas C (2005). Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer. Carcinogenesis 26, 923-930.
-
(2005)
Carcinogenesis
, vol.26
, pp. 923-930
-
-
Gorringe, L.K.1
Chin, S.2
Pharoah, P.3
Staines, M.J.4
Oliveira, C.5
Edwards, P.A.6
Caldas, C.7
-
31
-
-
33846065784
-
Aneuploidy acts both oncogenically and as a tumor suppressor
-
Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, and Cleveland DW (2007). Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 11, 25-36.
-
(2007)
Cancer Cell
, vol.11
, pp. 25-36
-
-
Weaver, B.A.1
Silk, A.D.2
Montagna, C.3
Verdier-Pinard, P.4
Cleveland, D.W.5
-
32
-
-
10644258336
-
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
-
Hanks S, Coleman K, Reid S, Plaja A, Firth H, Fitzpatrick D, Kidd A, Méhes K, Nash R, Robin N, et al. (2004). Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat Genet 36, 1159-1161.
-
(2004)
Nat Genet
, vol.36
, pp. 1159-1161
-
-
Hanks, S.1
Coleman, K.2
Reid, S.3
Plaja, A.4
Firth, H.5
Fitzpatrick, D.6
Kidd, A.7
Méhes, K.8
Nash, R.9
Robin, N.10
-
33
-
-
77950932096
-
Persistent telomere damage induces bypass of mitosis and tetraploidy
-
Davoli T, Denchi EL, and de Lange T (2010). Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell 141, 81-93.
-
(2010)
Cell
, vol.141
, pp. 81-93
-
-
Davoli, T.1
Denchi, E.L.2
de Lange, T.3
-
34
-
-
0032506125
-
Genetic instability of cancer cells is proportional to their degree of aneuploidy
-
Duesberg P, Rausch C, Rasnick D, and Hehlmann R (1998). Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proc Natl Acad Sci USA 95, 13692-13697.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13692-13697
-
-
Duesberg, P.1
Rausch, C.2
Rasnick, D.3
Hehlmann, R.4
-
35
-
-
0033388315
-
Genetic instability and Darwinian selection in tumours
-
Cahill DP, Kinzler KW, Vogelstein B, and Lengauer C (1999). Genetic instability and Darwinian selection in tumours. Trends Cell Biol 9, 57-60.
-
(1999)
Trends Cell Biol
, vol.9
, pp. 57-60
-
-
Cahill, D.P.1
Kinzler, K.W.2
Vogelstein, B.3
Lengauer, C.4
-
36
-
-
0028861725
-
Clonal evolution of an immunoblastic type non-Hodgkin's lymphoma with der(6)t(1;6)(q11;p11) as its primary cytogenetic abnormality
-
Gagos S, Iatridou-Kyrkou K, Liosi A, Karakitsos P, Papageorgaki P, Kyroudi A, and Pathak S (1995). Clonal evolution of an immunoblastic type non-Hodgkin's lymphoma with der(6)t(1;6)(q11;p11) as its primary cytogenetic abnormality. Cancer Genet Cytogenet 79, 59-63.
-
(1995)
Cancer Genet Cytogenet
, vol.79
, pp. 59-63
-
-
Gagos, S.1
Iatridou-Kyrkou, K.2
Liosi, A.3
Karakitsos, P.4
Papageorgaki, P.5
Kyroudi, A.6
Pathak, S.7
-
37
-
-
0029965540
-
Low-dose heparin treatment does not inhibit SW480 human colon cancer growth and metastasis in vivo
-
Antachopoulos CT, Gagos S, Iliopoulos DC, Karayannacos PE, Tseleni-Balafouta S, Alevras P, Koundouris C, and Skalkeas GD (1996). Low-dose heparin treatment does not inhibit SW480 human colon cancer growth and metastasis in vivo. In Vivo 10, 527-531.
-
(1996)
Vivo
, vol.10
, pp. 527-531
-
-
Antachopoulos, C.T.1
Gagos, S.2
Iliopoulos, D.C.3
Karayannacos, P.E.4
Tseleni-Balafouta, S.5
Alevras, P.6
Koundouris, C.7
Skalkeas, G.D.8
-
38
-
-
77957895775
-
Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity
-
Gagos S, Papaioannou G, Chiourea M, Merk-Loretti S, Jefford CE, Mikou P, Irminger-Finger I, Liossi A, Blouin JL, and Dahoun S (2008). Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity. Mol Cytogenet 1, 20.
-
(2008)
Mol Cytogenet
, vol.1
, pp. 20
-
-
Gagos, S.1
Papaioannou, G.2
Chiourea, M.3
Merk-Loretti, S.4
Jefford, C.E.5
Mikou, P.6
Irminger-Finger, I.7
Liossi, A.8
Blouin, J.L.9
Dahoun, S.10
-
39
-
-
0030249808
-
Cell senescence and a mechanism of clonal evolution leading to continuous cell proliferation, loss of heterozygosity, and tumor heterogeneity: Studies on two immortal colon cancer cell lines
-
Gagos S, Iliopoulos D, Tseleni-Balafouta S, Agapitos M, Antachopoulos C, Kostakis A, Karayannakos P, and Skalkeas G (1996). Cell senescence and a mechanism of clonal evolution leading to continuous cell proliferation, loss of heterozygosity, and tumor heterogeneity: studies on two immortal colon cancer cell lines. Cancer Genet Cytogenet 90, 157-165.
-
(1996)
Cancer Genet Cytogenet
, vol.90
, pp. 157-165
-
-
Gagos, S.1
Iliopoulos, D.2
Tseleni-Balafouta, S.3
Agapitos, M.4
Antachopoulos, C.5
Kostakis, A.6
Karayannakos, P.7
Skalkeas, G.8
-
43
-
-
0032553485
-
2 arrest after DNA damage
-
2 arrest after DNA damage. Science 282, 1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
44
-
-
0035943603
-
Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells
-
Ford LP, Zou Y, Pongracz K, Gryaznov SM, Shay JW, and Wright WE (2001). Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells. J Biol Chem 276, 32198-32203.
-
(2001)
J Biol Chem
, vol.276
, pp. 32198-32203
-
-
Ford, L.P.1
Zou, Y.2
Pongracz, K.3
Gryaznov, S.M.4
Shay, J.W.5
Wright, W.E.6
-
45
-
-
2442659384
-
Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition
-
Bechter OE, Zou Y, Walker W, Wright WE, and Shay JW (2004). Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition. Cancer Res 64, 3444-3451.
-
(2004)
Cancer Res
, vol.64
, pp. 3444-3451
-
-
Bechter, O.E.1
Zou, Y.2
Walker, W.3
Wright, W.E.4
Shay, J.W.5
-
46
-
-
0036636930
-
Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991
-
Seimiya H, Oh-hara T, Suzuki T, Naasani I, Shimazaki T, Tsuchiya K, and Tsuruo T (2002). Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991. Mol Cancer Ther 1, 657-665.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 657-665
-
-
Seimiya, H.1
Oh-Hara, T.2
Suzuki, T.3
Naasani, I.4
Shimazaki, T.5
Tsuchiya, K.6
Tsuruo, T.7
-
47
-
-
0038668792
-
Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy
-
Fabarius A, Hehlmann R, and Duesberg PH (2003). Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy. Cancer Genet Cytogenet 143, 59-72.
-
(2003)
Cancer Genet Cytogenet
, vol.143
, pp. 59-72
-
-
Fabarius, A.1
Hehlmann, R.2
Duesberg, P.H.3
-
48
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman F, Johansson B, and Mertens F (2007). The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 7, 233-245.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
49
-
-
79959652880
-
Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy
-
Ozery-Flato M, Linhart C, Trakhtenbrot L, Izraeli S, and Shamir R (2011). Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy. Genome Biol 12, R61.
-
(2011)
Genome Biol
, vol.12
-
-
Ozery-Flato, M.1
Linhart, C.2
Trakhtenbrot, L.3
Izraeli, S.4
Shamir, R.5
-
50
-
-
54249154250
-
Pericentromeric instability and spontaneous emergence of human neoacrocentric and minute chromosomes in the alternative pathway of telomere lengthening
-
Gagos S, Chiourea M, Christodoulidou A, Apostolou E, Raftopoulou C, Deustch S, Jefford CE, Irminger-Finger I, Shay JW, and Antonarakis SE (2008). Pericentromeric instability and spontaneous emergence of human neoacrocentric and minute chromosomes in the alternative pathway of telomere lengthening. Cancer Res 68, 8146-8155.
-
(2008)
Cancer Res
, vol.68
, pp. 8146-8155
-
-
Gagos, S.1
Chiourea, M.2
Christodoulidou, A.3
Apostolou, E.4
Raftopoulou, C.5
Deustch, S.6
Jefford, C.E.7
Irminger-Finger, I.8
Shay, J.W.9
Antonarakis, S.E.10
-
51
-
-
77949662980
-
Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres
-
Mitchell MA, Johnson JE, Pascarelli K, Beeharry N, Chiourea M, Gagos S, Lev D, von Mehren M, Kipling D, and Broccoli D (2010). Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres. Mol Cancer Ther 9, 682-692.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 682-692
-
-
Mitchell, M.A.1
Johnson, J.E.2
Pascarelli, K.3
Beeharry, N.4
Chiourea, M.5
Gagos, S.6
Lev, D.7
von Mehren, M.8
Kipling, D.9
Broccoli, D.10
-
52
-
-
79851490466
-
Alternative lengthening of telomeres-an enhanced chromosomal instability in aggressive non-MYCN amplified and telomere elongated neuroblastomas
-
Lundberg G, Sehic D, Länsberg JK, Øra I, Frigyesi A, Castel V, Navarro S, Piqueras M, Martinsson T, Noguera R, et al. (2011). Alternative lengthening of telomeres-an enhanced chromosomal instability in aggressive non-MYCN amplified and telomere elongated neuroblastomas. Genes Chromosomes Cancer 50, 250-262.
-
(2011)
Genes Chromosomes Cancer
, vol.50
, pp. 250-262
-
-
Lundberg, G.1
Sehic, D.2
Länsberg, J.K.3
øra, I.4
Frigyesi, A.5
Castel, V.6
Navarro, S.7
Piqueras, M.8
Martinsson, T.9
Noguera, R.10
-
53
-
-
33746558541
-
Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells
-
Pantic M, Zimmermann S, El Daly H, Opitz OG, Popp S, Boukamp P, and Martens UM (2006). Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells. Oncogene 25, 4413-4420.
-
(2006)
Oncogene
, vol.25
, pp. 4413-4420
-
-
Pantic, M.1
Zimmermann, S.2
El Daly, H.3
Opitz, O.G.4
Popp, S.5
Boukamp, P.6
Martens, U.M.7
-
54
-
-
0037444168
-
Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas
-
Pihan GA, Wallace J, Zhou Y, and Doxsey SJ (2003). Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas. Cancer Res 63, 1398-1404.
-
(2003)
Cancer Res
, vol.63
, pp. 1398-1404
-
-
Pihan, G.A.1
Wallace, J.2
Zhou, Y.3
Doxsey, S.J.4
-
55
-
-
77951976271
-
Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells
-
Nakamura JA, Redon EC, Bonner MW, and Sedelnikova AO (2009). Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells. Aging (Albany NY) 1, 212-219.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 212-219
-
-
Nakamura, J.A.1
Redon, E.C.2
Bonner, M.W.3
Sedelnikova, A.O.4
-
56
-
-
37549060645
-
Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres
-
Grudic A, Jul-Larsen A, Haring SJ, Wold MS, Lønning PE, Bjerkvig R, and Bøe SO (2007). Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres. Nucleic Acids Res 35, 7267-7278.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7267-7278
-
-
Grudic, A.1
Jul-Larsen, A.2
Haring, S.J.3
Wold, M.S.4
Lønning, P.E.5
Bjerkvig, R.6
Bøe, S.O.7
-
57
-
-
77955435598
-
Functional characterization of a cancer causing mutation in human replication protein A
-
Hass SC, Gakhar L, and Wold SM (2010). Functional characterization of a cancer causing mutation in human replication protein A. Mol Cancer Res 8, 1017-1026.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1017-1026
-
-
Hass, S.C.1
Gakhar, L.2
Wold, S.M.3
-
58
-
-
77954610995
-
Functions of alternative replication protein A in initiation and elongation
-
Mason CA, Roy R, Simmons TD, and Wold SM (2010). Functions of alternative replication protein A in initiation and elongation. Biochemistry 49, 5919-5928.
-
(2010)
Biochemistry
, vol.49
, pp. 5919-5928
-
-
Mason, C.A.1
Roy, R.2
Simmons, T.D.3
Wold, S.M.4
-
59
-
-
59649084380
-
Telomeres, histone code, and DNA damage response
-
Misri S, Pandita S, Kumar R, and Pandite KT (2008). Telomeres, histone code, and DNA damage response. Cytogenet Genome Res 122, 297-307.
-
(2008)
Cytogenet Genome Res
, vol.122
, pp. 297-307
-
-
Misri, S.1
Pandita, S.2
Kumar, R.3
Pandite, K.T.4
-
60
-
-
77951977178
-
'A mover and a shaker': 53BP1 allows DNA doublestrand breaks a chance to dance and unite
-
Goodarzi AA and Jeggo AP (2009). 'A mover and a shaker': 53BP1 allows DNA doublestrand breaks a chance to dance and unite. F1000 Biol Rep 1+21.
-
(2009)
F1000 Biol Rep
-
-
Goodarzi, A.A.1
Jeggo, A.P.2
-
61
-
-
79955512470
-
Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions
-
Zhao Y, Abreu E, Kim J, Stadler G, Eskiocak U, Terns MP, Shay JW, and Wright WE (2011). Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions. Mol Cell 42, 297-307.
-
(2011)
Mol Cell
, vol.42
, pp. 297-307
-
-
Zhao, Y.1
Abreu, E.2
Kim, J.3
Stadler, G.4
Eskiocak, U.5
Terns, M.P.6
Shay, J.W.7
Wright, W.E.8
-
62
-
-
80052692748
-
Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines
-
Zhang Y, Cai L, Wei RX, Hu H, Jin W, and Zhu XB (2011). Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines. Oncol Lett 6, 1327-1332.
-
(2011)
Oncol Lett
, vol.6
, pp. 1327-1332
-
-
Zhang, Y.1
Cai, L.2
Wei, R.X.3
Hu, H.4
Jin, W.5
Zhu, X.B.6
-
63
-
-
0042166174
-
Chromosome aberrations in solid tumors
-
Albertson DG, Collins C, McCormick F, and Gray JW (2003). Chromosome aberrations in solid tumors. Nat Genet 34, 369-376.
-
(2003)
Nat Genet
, vol.34
, pp. 369-376
-
-
Albertson, D.G.1
Collins, C.2
McCormick, F.3
Gray, J.W.4
-
64
-
-
84860782006
-
Absolute quantification of somatic DNA alterations in human cancer
-
Carter LS, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, et al. (2012). Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol 30, 413-421.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 413-421
-
-
Carter, L.S.1
Cibulskis, K.2
Helman, E.3
McKenna, A.4
Shen, H.5
Zack, T.6
Laird, P.W.7
Onofrio, R.C.8
Winckler, W.9
Weir, B.A.10
-
65
-
-
16344391652
-
McClintock's controlling elements: The full story
-
Jones RN (2005). McClintock's controlling elements: the full story. Cytogenet Genome Res 109, 90-103.
-
(2005)
Cytogenet Genome Res
, vol.109
, pp. 90-103
-
-
Jones, R.N.1
-
66
-
-
77953951382
-
Are aneuploidy and chromosome breakage caused by a CINgle mechanism?
-
Martinez AC and van Wely KH (2010). Are aneuploidy and chromosome breakage caused by a CINgle mechanism? Cell Cycle 12, 2275-2280.
-
(2010)
Cell Cycle
, vol.12
, pp. 2275-2280
-
-
Martinez, A.C.1
van Wely, K.H.2
-
67
-
-
33749369156
-
Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication
-
Lazzerini Denchi E, Celli G, and de Lange T (2006). Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication. Genes Dev 20, 2648-2653.
-
(2006)
Genes Dev
, vol.20
, pp. 2648-2653
-
-
Lazzerini, D.E.1
Celli, G.2
de Lange, T.3
-
68
-
-
33846703426
-
Hallmarks of telomeres in ageing research
-
Shay JW and Wright WE (2007). Hallmarks of telomeres in ageing research. J Pathol 211, 114-123.
-
(2007)
J Pathol
, vol.211
, pp. 114-123
-
-
Shay, J.W.1
Wright, W.E.2
-
69
-
-
84862288783
-
Cancer and telomeres-an ALTernative to telomerase
-
Shay JW, Reddel RR, and Wright WE (2012). Cancer and telomeres-an ALTernative to telomerase. Science 336, 1388-1390.
-
(2012)
Science
, vol.336
, pp. 1388-1390
-
-
Shay, J.W.1
Reddel, R.R.2
Wright, W.E.3
-
70
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C, Kinzler KW, and Vogelstein B (1998). Genetic instabilities in human cancers. Nature 396, 643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
71
-
-
70349158606
-
Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination
-
Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, and Londoño-Vallejo A (2009). Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc Natl Acad Sci USA 106, 15726-15731.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15726-15731
-
-
Draskovic, I.1
Arnoult, N.2
Steiner, V.3
Bacchetti, S.4
Lomonte, P.5
Londoño-Vallejo, A.6
-
72
-
-
23944516520
-
Conditional telomerase induction causes proliferation of hair follicle stem cells
-
Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, and Artandi SE (2005). Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 436, 1048-1052.
-
(2005)
Nature
, vol.436
, pp. 1048-1052
-
-
Sarin, K.Y.1
Cheung, P.2
Gilison, D.3
Lee, E.4
Tennen, R.I.5
Wang, E.6
Artandi, M.K.7
Oro, A.E.8
Artandi, S.E.9
-
73
-
-
54849434623
-
A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis
-
Imamura S, Uchiyama J, Koshimizu E, Hanai J, Raftopoulou C, Murphey RD, Bayliss PE, Imai Y, Burns CE, Masutomi K, et al. (2008). A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. PLoS One 3, e3364.
-
(2008)
PLoS One
, vol.3
-
-
Imamura, S.1
Uchiyama, J.2
Koshimizu, E.3
Hanai, J.4
Raftopoulou, C.5
Murphey, R.D.6
Bayliss, P.E.7
Imai, Y.8
Burns, C.E.9
Masutomi, K.10
|