Within-population genetic diversity of Plasmodium falciparum vaccine candidate antigens reveals geographic distance from a Central sub-Saharan African origin

Vaccine

Volumn 31, Issue 9, 2013, Pages 1334-1339

  Tanabe, Kazuyuki ^a   Mita, Toshihiro ^b   Palacpac, Nirianne M Q ^a   Arisue, Nobuko ^a   Tougan, Takahiro ^a   Kawai, Satoru ^c   Jombart, Thibaut ^d   Kobayashi, Fumie ^e   Horii, Toshihiro ^a  

^a OSAKA UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c DOKKYO MEDICAL UNIVERSITY   (Japan)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e KYORIN UNIVERSITY   (Japan)

Author keywords

AMA1; CSP; Malaria; MSP1; Plasmodium falciparum; Vaccine

Indexed keywords

ANTIGEN; APICAL MEMBRANE ANTIGEN 1; CIRCUMSPOROZOITE PROTEIN; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 1; PARASITE ANTIGEN;

AFRICA SOUTH OF THE SAHARA; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DRUG TARGETING; GENE SEQUENCE; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HUMAN; IMMUNE RESPONSE; LONG TERM POTENTIATION; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; PACIFIC ISLANDS; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; POPULATION GENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTHEAST ASIA;

AFRICA; ANTIGENS, PROTOZOAN; ASIA, SOUTHEASTERN; DNA, PROTOZOAN; HUMANS; MALARIA VACCINES; MEMBRANE PROTEINS; MEROZOITE SURFACE PROTEIN 1; MOLECULAR SEQUENCE DATA; OCEANIA; PHYLOGEOGRAPHY; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS; SEQUENCE ANALYSIS, DNA;

EID: 84873479648     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.12.039     Document Type: Article

References (47)

1. World malaria report 2011 2011, WHO, WHO.
2. Schwartz L., Brown G.V., Genton B., Moorthy V.S. A review of malaria vaccine clinical projects based on the WHO rainbow table. Malar J 2012, 11:11.
3. Tanabe K., Mita T., Jombart T., Eriksson A., Horibe S., Palacpac N., et al. Plasmodium falciparum accompanied the human expansion out-of-Africa. Curr Biol 2010, 70:1-7.
4. Mellars P. Going east: new genetic and archaeological perspectives on the modern human colonization of Eurasia. Science 2006, 313:796-800.
5. Forster P. Ice Ages and the mitochondrial DNA chronology of human dispersals: a review. Philos Trans R Soc Lond B Biol Sci 2004, 359:255-264.
6. Mu J., Awadalla P., Duan J., McGee K.M., Keebler J., Seydel K., et al. Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome. Nat Genet 2007, 39:126-130.
7. Volkman S.K., Sabeti P.C., DeCaprio D., Neafsey D.E., Schaffner S.F., Milner D.A., et al. A genome-wide map of diversity in Plasmodium falciparum. Nat Genet 2007, 39:113-119.
8. Coppi A., Natarajan R., Pradel G., Bennett B.L., James E.R., Roggero M.A., et al. The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host. J Exp Med 2011, 208:341-356.
9. Zavala F., Tam J.P., Hollingdale M.R., Cochrane A.H., Quakyi I., Nussenzweig R.S., et al. Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science 1985, 228:1436-1440.
10. John C.C., Tande A.J., Moormann A.M., Sumba P.O., Lanar D.E., Min X.M., et al. Antibodies to pre-erythrocytic Plasmodium falciparum antigens and risk of clinical malaria in Kenyan children. J Infect Dis 2008, 197:519-526.
11. Agnandji S.T., Lell B., Soulanoudjingar S.S., Fernandes J.F., Abossolo B.P., Conzelmann C., et al. First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. N Engl J Med 2011, 365:1863-1875.
12. Healer J., Crawford S., Ralph S., McFadden G., Cowman A.F. Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites. Infect Immun 2002, 70:5751-5758.
13. Alexander D.L., Arastu-Kapur S., Dubremetz J.F., Boothroyd J.C. Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii. Eukaryot Cell 2006, 5:1169-1173.
14. Courtin D., Oesterholt M., Huismans H., Kusi K., Milet J., Badaut C., et al. The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria. PLoS One 2009, 4:e7590.
15. Polley S.D., Mwangi T., Kocken C.H., Thomas A.W., Dutta S., Lanar D.E., et al. Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria. Vaccine 2004, 23:718-728.
16. Holder A.A., Freeman R.R. Protective antigens of rodent and human bloodstage malaria. Philos Trans R Soc Lond B Biol Sci 1984, 307:171-177.
17. 33 as a noncovalently associated complex with other fragments of the MSP1. Mol Biochem Parasitol 1992, 50:307-315.
18. Fowkes F.J., Richards J.S., Simpson J.A., Beeson J.G. The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: a systematic review and meta-analysis. PLoS Med 2010, 7:e1000218.
19. Sakihama N., Kimura M., Hirayama K., Kanda T., Na-Bangchang K., Jongwutiwes S., et al. Allelic recombination and linkage disequilibrium within Msp-1 of Plasmodium falciparum, the malignant human malaria parasite. Gene 1999, 230:47-54.
20. Sakihama N., Kaneko A., Hattori T., Tanabe K. Limited recombination events in merozoite surface protein-1 alleles of Plasmodium falciparum on islands. Gene 2001, 279:41-48.
21. Sakihama N., Ohmae H., Bakote'e B., Kawabata M., Hirayama K., Tanabe K. Limited allelic diversity of Plasmodium falciparum merozoite surface protein 1 gene from populations in the Solomon Islands. Am J Trop Med Hyg 2006, 4:31-40.
22. Sakihama N., Nakamura M., Palanca A.A., Argubano R.A., Realon E.P., Larracas A.L., et al. Allelic diversity in the merozoite surface protein 1 gene of Plasmodium falciparum on Palawan Island, the Philippines. Parasitol Int 2007, 56:185-194.
23. Tanabe K., Sakihama N., Rooth I., Björkman A., Färnert A. High frequency of recombination-driven allelic diversity and temporal variation of Plasmodium falciparum msp1 in Tanzania. Am J Trop Med Hyg 2007, 76:1037-1045.
24. Tanabe K., Arisue N., Palacpac N.M.Q., Yagi M., Tougan T., Honma H., et al. Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA5. Vaccine 2012, 30:1583-1593.
25. Tanabe K., Mackay M., Goman M., Scaife J.G. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum. J Mol Biol 1987, 195:273-287.
26. Tanabe K., Sakihama N., Walliker D., Babiker H., Abdel-Muhsin A.A., Bakote'e B., et al. Allelic dimorphism-associated restriction of recombination in Plasmodium falciparum msp1. Gene 2007, 397:153-160.
27. Excoffier L., Laval G., Schneider S. Arlequin (version 3.0): an integrated software package for population genetics data analysis. Evol Bioinform Online 2005, 1:47-50.
28. Ramachandran S., Deshpande O., Roseman C.C., Rosenberg N.A., Feldman M.W., Cavalli-Sforza L.L. Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci USA 2005, 102:15942-15947.
29. Prugnolle F., Manica A., Balloux F. Geography predicts neutral genetic diversity of human populations. Curr Biol 2005, 15:R159-R160.
30. Liu H., Prugnolle F., Manica A., Balloux F. A geographically explicit genetic model of worldwide human-settlement history. Am J Hum Genet 2006, 79:230-237.
31. Li J.Z., Absher D.M., Tang H., Southwick A.M., Casto A.M., Ramachandran S., et al. Worldwide human relationships inferred from genome-wide patterns of variation. Science 2008, 319:1100-1104.
32. Joy D.A., Feng X., Mu J., Furuya T., Chotivanich K., Krettli A.U., et al. Early origin and recent expansion of Plasmodium falciparum. Science 2003, 300:318-321.
33. Anderson T.J., Haubold B., Williams J.T., Estrada-Franco J.G., Richardson L., Mollinedo R., et al. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol Biol Evol 2000, 17:1467-1482.
34. Kumar S., Miller L.H., Quakyi I.A., Keister D.B., Houghten R.A., Maloy W.L., et al. Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum. Nature 1988, 334:258-260.
35. Healer J., Murphy V., Hodder A.N., Masciantonio R., Gemmill A.W., Anders R.F., et al. Allelic polymorphisms in apical membrane antigen-1 are responsible for evasion of antibody-mediated inhibition in Plasmodium falciparum. Mol Microbiol 2004, 52:159-168.
36. Dutta S., Lee S.Y., Butchelor A.H., Lanar D.E. Structural basis of antigenic escape of a malaria vaccine candidate. Proc Natl Acad Sci USA 2007, 104:12488-12493.
37. Lyon J.A., Angov E., Fay M.P., Sullivan J.S., Girourd A.S., Robinson S.J., et al. Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses. PLoS One 2008, 3:e2830.
38. Genton B., Betuela I., Felger I., Al-Yaman F., Anders R.F., Saul A., et al. A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea. J Infect Dis 2002, 185:820-827.
39. Tanabe K., Sakihama N., Kaneko A. Stable SNPs in malaria antigen genes in isolated populations. Science 2004, 303:493.
40. Polley S.D., Chokejindachai W., Conway D.J. Allele frequency-based analyses robustly map sequence sites under balancing selection in a malaria vaccine candidate antigen. Genetics 2003, 165:555-561.
41. Duan J., Mu J., Thera M.A., Joy D., Kosakovsky Pond S.L., Diemert D., et al. Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design. Proc Natl Acad Sci USA 2008, 105:7857-7862.
42. Verra F., Chokejindachai W., Weedall G.D., Polley S.D., Mwangi T.W., Marsh K., et al. Contrasting signatures of selection on the Plasmodium falciparum erythrocyte binding antigen gene family. Mol Biochem Parasitol 2006, 149:182-190.
43. Polley S.D., Tetteh K.K., Lloyd J.M., Akpogheneta O.J., Greenwood B.M., Bojang K.A., et al. Plasmodium falciparum merozoite surface protein 3 is a target of allele-specific immunity and alleles are maintained by natural selection. J Infect Dis 2007, 195:279-287.
44. Maitland K., Williams T.N. Malaria mortality: the pacific enigma. Parasitol Today 1998, 14:258-259.
45. Kelly-Hope L.A., McKenzie F.E. The multiplicity of malaria transmission: a review of entomological inoculation rate measurements and methods across sub-Saharan Africa. Malar J 2009, 8:19.
46. Saul A. Malaria mortality: the pacific enigma-reply. Parasitol Today 1998, 14:293-294.
47. Färnert A., Rooth I., Svensson A., Snounou G., Bjorkman A. Complexity of Plasmodium falciparum infections is consistent over time and protects against clinical disease in Tanzanian children. J Infect Dis 1999, 179:989-995.