An International survey-based algorithm for the pharmacologic treatment of irritability in Huntington's disease

PLoS Currents

Volumn , Issue SEP, 2011, Pages

  Groves, Mark ^a   van Duijn, Erik ^b,c   Anderson, Karen ^d   Craufurd, David ^e   Edmondson, Mary C ^f   Goodman, Nathan ^g   van Kammen, Daniel P ^h   Goodman, LaVonne ⁱ  

^a BETH ISRAEL MEDICAL CENTER   (United States)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Centre for Mental Health Care Delfland   (Netherlands)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

^g INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^h CNS Drug Development consultant   (United States)

ⁱ Huntington's Disease Drug Works   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CITALOPRAM; CLOMIPRAMINE; ESCITALOPRAM; FLUOXETINE; HALOPERIDOL; MIRTAZAPINE; MOOD STABILIZER; NEUROLEPTIC AGENT; OLANZAPINE; PAROXETINE; PROPRANOLOL; QUETIAPINE; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; SULPIRIDE; TIAPRIDE; TRICYCLIC ANTIDEPRESSANT AGENT;

ALGORITHM; ANXIETY; ARTICLE; CLINICAL DECISION MAKING; DEPRESSION; DRUG EFFICACY; DRUG MEGADOSE; FOLLOW UP; HEALTH SURVEY; HUMAN; HUNTINGTON CHOREA; HYPERSEXUALITY; INSOMNIA; IRRITABILITY; LOW DRUG DOSE; MONOTHERAPY; OBSESSIVE COMPULSIVE DISORDER; PSYCHOSIS; QUESTIONNAIRE;

EID: 84873478123     PISSN: None     EISSN: 21573999     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell. 1993 Mar 26;72(6):971-83. PubMed PMID: 8458085.
2. Anderson KE, Marder KS. An overview of psychiatric symptoms in Huntington's disease. Curr Psychiatry Rep. 2001 Oct;3(5):379-88. Review. PubMed PMID: 11559474.
3. Snaith RP, Taylor CM. Irritability: definition, assessment and associated factors. Br J Psychiatry. 1985 Aug;147:127-36. PubMed PMID: 3840045.
4. van Duijn E, Kingma EM, van der Mast RC. Psychopathology in verified Huntington's disease gene carriers. J Neuropsychiatry Clin Neurosci. 2007 Fall;19(4):441-8. Review. PubMed PMID: 18070848.
5. Paulsen JS, Ready RE, Hamilton JM, Mega MS, Cummings JL. Neuropsychiatric aspects of Huntington's disease. J Neurol Neurosurg Psychiatry. 2001 Sep;71(3):310-4. PubMed PMID: 11511702; PubMed Central PMCID: PMC1737562.
6. Chatterjee A, Anderson KE, Moskowitz CB, Hauser WA, Marder KS. A comparison of self-report and caregiver assessment of depression, apathy, and irritability in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2005 Summer;17(3):378-83. PubMed PMID: 16179661.
7. PLoS article No PMID yet
8. Klöppel S, Stonnington CM, Petrovic P, Mobbs D, Tüscher O, Craufurd D, Tabrizi SJ, Frackowiak RS. Irritability in pre-clinical Huntington's disease. Neuropsychologia. 2010 Jan;48(2):549-57. Epub 2009 Oct 28. PubMed PMID: 19878688; PubMed Central PMCID: PMC2809920.
9. Thompson JC, Snowden JS, Craufurd D, Neary D. Behavior in Huntington's disease: dissociating cognition-based and mood-based changes. J Neuropsychiatry Clin Neurosci. 2002 Winter;14(1):37-43. PubMed PMID: 11884653.
10. van Duijn E. Treatment of Irritability in Huntington's Disease. Curr Treat Options Neurol. 2010 Sep;12(5):424-33. Epub 2010 Jul 10. PubMed PMID: 20730109; PubMed Central PMCID: PMC2918785.
11. Mestre T, Ferreira J, Coelho MM, Rosa M, Sampaio C. Therapeutic interventions for symptomatic treatment in Huntington's disease. Cochrane Database Syst Rev. 2009 Jul 8;(3):CD006456. Review. PubMed PMID: 19588393.
12. Anderson K, Craufurd D, Edmondson MC, Goodman N, Groves M, van Duijn E, van Kammen DP, Goodman L. An International Survey-based Algorithm for the Pharmacologic Treatment of Obsessive-Compulsive Behaviors in Huntington's Disease. PLoS Curr. 2011 Sep 20;3:RRN1261. PubMed PMID: 21947193; PubMed Central PMCID: PMC3177175.
13. Burgunder JM, Guttman M, Perlman S, Goodman N, van Kammen DP, Goodman L. An International Survey-based Algorithm for the Pharmacologic Treatment of Chorea in Huntington's Disease. PLoS Curr. 2011 Aug 30;3:RRN1260. PubMed PMID: 21975581.
14. Ranen NG, Lipsey JR, Treisman G, Ross CA. Sertraline in the treatment of severe aggressiveness in Huntington's disease. J Neuropsychiatry Clin Neurosci. 1996 Summer;8(3):338-40. PubMed PMID: 8854307.
15. Squitieri F, Cannella M, Piorcellini A, Brusa L, Simonelli M, Ruggieri S. Short-term effects of olanzapine in Huntington disease. Neuropsychiatry Neuropsychol Behav Neurol. 2001 Jan;14(1):69-72. PubMed PMID: 11234911.
16. Grove VE Jr, Quintanilla J, DeVaney GT. Improvement of Huntington's disease with olanzapine and valproate. N Engl J Med. 2000 Sep 28;343(13):973-4. PubMed PMID: 11012330.
17. Leonard DP, Kidson MA, Brown JG, Shannon PJ, Taryan S. A double blind trial of lithium carbonate and haloperidol in Huntington's chorea. Aust N Z J Psychiatry. 1975 Jun;9(2):115-8. PubMed PMID: 125578.
18. Curtis A, Rickards H. Nabilone could treat chorea and irritability in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2006 Fall;18(4):553-4. PubMed PMID: 17135385.
19. Fleminger S, Greenwood RJ, Oliver DL. Pharmacological management for agitation and aggression in people with acquired brain injury. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003299. Review. PubMed PMID: 17054165.
20. Fleminger S, Greenwood RJ, Oliver DL. Pharmacological management for agitation and aggression in people with acquired brain injury. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003299. Review. PubMed PMID: 17054165.
21. Bhandary AN, Masand PS. Buspirone in the management of disruptive behaviors due to Huntington's disease and other neurological disorders. Psychosomatics. 1997 Jul-Aug;38(4):389-91. PubMed PMID: 9217410.
22. Byrne A, Martin W, Hnatko G. Beneficial effects of buspirone therapy in Huntington's disease. Am J Psychiatry. 1994 Jul;151(7):1097. PubMed PMID: 8010374.