Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage

Neurocritical Care

Volumn 18, Issue 1, 2013, Pages 13-19

  Ortega Gutierrez, Santiago ^a,b   Thomas, Jiz ^c   Reccius, Andres ^a   Agarwal, Sachin ^a   Lantigua, Hector ^a   Li, Min ^a   Carpenter, Amanda M ^a   Mayer, Stephan A ^a   Schmidt, J Michael ^a   Lee, Kiwon ^a   Claassen, Jan ^a   Badjatia, Neeraj ^a   Lesch, Christine ^c  

^a NEUROLOGICAL INSTITUTE   (United States)

^b NewYork Presbyterian Hospital ^*  (United States)

^c NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

Blood pressure; ICH; Labetalol; Nicardipine; SAH

Indexed keywords

LABETALOL; NICARDIPINE;

ADULT; AGED; BLOOD PRESSURE REGULATION; BLOOD PRESSURE VARIABILITY; BRADYCARDIA; BRAIN HEMORRHAGE; COMPARATIVE EFFECTIVENESS; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PATIENT MONITORING; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; SUBARACHNOID HEMORRHAGE; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA;

ADULT; AGED; ANTIHYPERTENSIVE AGENTS; CEREBRAL HEMORRHAGE; COHORT STUDIES; DRUG THERAPY, COMBINATION; EARLY MEDICAL INTERVENTION; FEMALE; HUMANS; HYPERTENSION; INFUSIONS, INTRAVENOUS; LABETALOL; MALE; MIDDLE AGED; NICARDIPINE; RETROSPECTIVE STUDIES; SUBARACHNOID HEMORRHAGE; TREATMENT OUTCOME;

EID: 84873451838     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-012-9782-1     Document Type: Review

References (16)

1. Shah QA, Ezzeddine MA, Qureshi AI. Acute hypertension in intracerebral hemorrhage: pathophysiology and treatment. J Neurol Sci. 2007;261:74-9.
2. Bederson JB, Connoly S Jr, Batjer H, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage. Stroke. 2009;40:994-1025.
3. Morgenstern LB, Hemphill JC III, Anderson C, et al. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010;41:2108-29.
4. Mayer SA, Kurtz P, Wyman A, et al. Clinical practices, complications, and mortality in neurological patients with acute severe hypertension: studying the treatment of acute hypertension registry. Crit Care Med. 2011;39(10):2330-6.
5. Malesker MA, Hilleman DE. Intravenous labetalol compared with intravenous nicardipine in the management of hypertension in critically ill patients. J Crit Care. 2012 (in press).
6. Elastrous S, Nouira S, Besbes LO, et al. Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol. Intensive Care Med. 2002;28:1281-6.
7. Peacock WF, Varon J, Baumann BB, et al. CLUE: a randomized comparative effectiveness trial of IV nicardipine versus labetalol use in the emergency department. Crit Care. 2011;15:R157.
8. Liu-DeRyke X, Janisse J, Coplin WM, Parker D Jr, Norris G, Rhoney DH. A comparison of nicardipine and labetalol for acute hypertension management following stroke. Neurocrit Care. 2008;9:167-76.
9. Kross RA, Ferri E, Leung D, et al. A comparative study between a calcium channel blocker (nicardipine) and a combined α-β-blocker (labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. Anesth Analg. 2000;91:904-9.
10. Woloszyn AV, McAllen KJ, Figueroa BE, DeShane RS, Barletta JF. Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2012;16(3):376-80.
11. Kothari RU, Brott T, Broderick JP, et al. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304-5.
12. Anderson CS, Huang Y, Wang JG, et al. Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomized pilot trial. Lancet Neurol. 2008;7:391-9.
13. Antihypertensive treatment of acute cerebral hemorrhage (ATACH) investigators. Antihypertensive treatment of acute cerebral hemorrhage. Crit Care Med. 2010;38:637-48.
14. Graffagnino C, Bergese S, Love J, et al. Clevidipine rapidly and safely reduces blood pressure in patients with acute intracerebral hemorrhage: interim results of the ACCELERATE trial - first clinical experience in ICH. Neurocrit Care. 2009;11:S7.
15. Adams HP, del Zoppo G, Alberts MJ, et al. Guidelines for the early management of patients with ischemic stroke. Stroke. 2007;38:1655-711.
16. Sansing LH, Messe SR, Cucchiara BL, Lyden PD, Kasner SE. Anti-adrenergic medication and edema development after intracerebral hemorrhage. Neurocrit Care. 2011;14:395-400.