Prevalence of multidrug-resistant gram-negative bacilli producing extended-spectrum β-lactamases (ESBLs) and ESBL genes in solid organ transplant recipients

Transplant Infectious Disease

Volumn 15, Issue 1, 2013, Pages 14-21

  Men, T Y ^a   Wang, J N ^a   Li, H ^b   Gu, Y ^c   Xing, T H ^c   Peng, Z H ^c   Zhong, L ^c  

^a THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

Author keywords

ESBL genes; Multidrug resistant gram negative bacilli; Solid organ transplantation

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE CTX M; BETA LACTAMASE INHIBITOR; BETA LACTAMASE SHV; BETA LACTAMASE TEM 1; CARBAPENEM; CEPHALOSPORIN DERIVATIVE; EXTENDED SPECTRUM BETA LACTAMASE; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADULT; AGAR DILUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHOLANGITIS; FEMALE; GENE IDENTIFICATION; GENE SEQUENCE; GENOTYPE; GRAFT RECIPIENT; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE INFECTION; HUMAN; INCIDENCE; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; MULTIDRUG RESISTANCE; MULTIPLEX POLYMERASE CHAIN REACTION; ORGAN TRANSPLANTATION; PERITONITIS; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; SEPSIS; URINARY TRACT INFECTION;

ADULT; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MULTIPLEX POLYMERASE CHAIN REACTION; PREVALENCE;

EID: 84873448943     PISSN: 13982273     EISSN: 13993062     Source Type: Journal    
DOI: 10.1111/tid.12001     Document Type: Article

References (27)

1. Wadl M, Heckenbach K, Noll I, et al. Increasing occurrence of multidrug-resistance in Acinetobacter baumannii isolates from four German University Hospitals, 2002-2006. Infection 2010; 38 (1): 47-51.
2. Samuelsen O, Toleman MA, Sundsfjord A, et al. Molecular epidemiology of metallo-beta-lactamase-producing Pseudomonas aeruginosa isolates from Norway and Sweden shows import of international clones and local clonal expansion. Antimicrob Agents Chemother 2010; 54 (1): 346-352.
3. Falagas ME, Maraki S, Karageorgopoulos DE, Kastoris AC, Mavromanolakis E, Samonis G. Antimicrobial susceptibility of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Enterobacteriaceae isolates to fosfomycin. Int J Antimicrob Agents 2010; 35 (3): 240-243.
4. Singh N, Wagener MM, Obman A, Cacciarelli TV, de Vera ME, Gayowski T. Bacteremias in liver transplant recipients: shift toward gram-negative bacteria as predominant pathogens. Liver Transpl 2004; 10 (7): 844-849.
5. Singh N, Gayowski T, Rihs JD, Wagener MM, Marino IR. Evolving trends in multiple-antibiotic-resistant bacteria in liver transplant recipients: a longitudinal study of antimicrobial susceptibility patterns. Liver Transpl 2001; 7 (1): 22-26.
6. Hawkey PM. Prevalence and clonality of extended-spectrum beta-lactamases in Asia. Clin Microbiol Infect 2008; 14 (1): 159-165.
7. Hirakata Y, Matsuda J, Miyazaki Y, et al. Regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998-2002). Diagn Microbiol Infect Dis 2005; 52 (4): 323-329.
8. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008; 36 (5): 309-332.
9. CLSI. Performance Standards for Antimicrobial Susceptibility Testing; Eighteenth Informational Supplement, M100-S16. Wayne, PA: Clinical and Laboratory Standards Institute, 2008.
10. Yong D, Lee K, Yum JH, Shin HB, Rossolini GM, Chong Y. Imipenem-EDTA disk method for differentiation of metallo-β-lactamases producing clinical isolates of Pseudomonas spp and Acinetobacter spp. J Clin Microbiol 2002; 40 (10): 3798-3801.
11. Lal P, Kapil A, Das BK, Sood S. Occurrence of TEM & SHV gene in extended spectrum beta-lactamases (ESBLs) producing Klebsiella sp isolated from a tertiary care hospital. Indian J Med Res 2007; 125 (2): 173-178.
12. Park JH, Lee SH, Jeong SH, et al. Characterization and prevalence of Escherichia coli and Klebsiella pneumoniae isolates producing an extended-spectrum beta-lactamase from Korean hospitals. Korean J Lab Med 2003; 23: 18-24.
13. Shibata N, Kurokawa H, Doi Y, et al. PCR classification of CTX-M-Type beta-lactamase genes identified in clinically isolated gram-negative bacilli in Japan. Antimicrob Agents Chemother 2006; 50 (2): 791-795.
14. Shi SH, Kong HS, Xu J, et al. Multidrug resistant gram-negative bacilli as predominant bacteremic pathogens in liver transplant recipients. Transpl Infect Dis 2009; 11 (5): 405-412.
15. Huys G, Cnockaert M, Vaneechoutte M, et al. Distribution of tetracycline resistance genes in genotypically related and unrelated multiresistant Acinetobacter baumannii strains from different European hospitals. Res Microbiol 2005; 156 (3): 348-355.
16. Hawser SP, Bouchillon SK, Hoban DJ, Badal RE, Hsueh PR, Paterson DL. Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. Antimicrob Agents Chemother 2009; 53 (8): 3280-3284.
17. Ling TK, Xiong J, Yu Y, Lee CC, Ye H, Hawkey PM. Multicenter antimicrobial susceptibility survey of gram-negative bacteria isolated from patients with community-acquired infections in the People's Republic of China. Antimicrob Agents Chemother 2006; 50 (1): 374-378.
18. Shahcheraghi F, Nikbin VS, Feizabadi MM. Identification and genetic characterization of metallo-beta-lactamase-producing strains of Pseudomonas aeruginosa in Tehran, Iran. New Microbiol 2010; 33 (3): 243-248.
19. Datta N, Kontomichalou P. Penicillinase synthesis controlled by infectious R factors in Enterobacteriaceae. Nature 1965; 208 (5007): 239-241.
20. Liu W, Chen L, Li H, et al. Novel CTX-M beta-lactamase genotype distribution and spread into multiple species of Enterobacteriaceae in Changsha, Southern China. J Antimicrob Chemother 2009; 63 (5): 895-900.
21. Bernard H, Tancrede C, Livrelli V, Morand A, Barthelemy M, Labia R. A novel plasmid-mediated extended-spectrum beta-lactamase not derived from TEM- or SHV-type enzymes. J Antimicrob Chemother 1992; 29 (5): 590-592.
22. Canton R, Coque TM. The CTX-M beta-lactamase pandemic. Curr Opin Microbiol 2006; 9 (5): 466-475.
23. Rossolini GM, D'Andrea MM, Mugnaioli C. The spread of CTX-M-type extended-spectrum beta-lactamases. Clin Microbiol Infect 2008; 14 (1): 33-41.
24. Livermore DM, Canton R, Gniadkowski M, et al. CTX-M: changing the face of ESBLs in Europe. J Antimicrob Chemother 2007; 59 (2): 165-174.
25. Rodriguez-Bano J, Navarro MD, Romero L, et al. Bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli in the CTX-M era: a new clinical challenge. Clin Infect Dis 2006; 43 (11): 1407-1414.
26. Zhong L, Men TY, Li H, et al. Multidrug-resistant gram-negative bacterial infections after liver transplantation - spectrum and risk factors. J Infect 2012; 64 (3): 299-310. Epub 2011 Dec 14.
27. Lautenbach E, Patel JB, Bilker WB, Edelstein PH, Fishman NO. Extended spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes. Clin Infect Dis 2001; 32 (8): 1162-1171.