Pharmacokinetic profile of liposome bupivacaine injection following a single administration at the surgical site

Clinical Drug Investigation

Volumn 33, Issue 2, 2013, Pages 109-115

  Hu, Deedee ^a   Onel, Erol ^b   Singla, Neil ^c   Kramer, William G ^d   Hadzic, Admir ^e  

^a MEMORIAL HERMANN HOSPITAL   (United States)

^b Pacira Pharmaceuticals Inc   (United States)

^c Lotus Clinical Research   (United States)

^d Kramer Consulting LLC   (United States)

^e ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; PLACEBO;

ANXIETY; APPETITE; ASTHENIA; BRADYCARDIA; BUNIONECTOMY; CONFUSION; CONSTIPATION; COUGHING; DIZZINESS; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DYSPEPSIA; DYSPNEA EXERTIONAL; ERYTHEMA; FATIGUE; FEVER; GLUCOSE BLOOD LEVEL; HEADACHE; HEMORRHAGIC ANEMIA; HEMORRHOIDECTOMY; HERNIOPLASTY; HUMAN; HYPERTENSION; HYPOAESTHESIA; HYPOKALEMIA; HYPOTENSION; INCISION SITE EDEMA; INCISION SITE HEMORRHAGE; INSOMNIA; JOINT SWELLING; LETHARGY; LOCAL ANESTHESIA; LOCALIZED EDEMA; MULTICENTER STUDY (TOPIC); MUSCLE SPASM; NAUSEA; OROPHARYNX PAIN; PERIPHERAL EDEMA; PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PLASMA CONCENTRATION-TIME CURVE; POSTOPERATIVE ANEMIA; PRESYNCOPE; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SIDE EFFECT; SINGLE DRUG DOSE; SOMNOLENCE; SURGICAL WOUND; SYSTEMATIC REVIEW; TACHYCARDIA; TOTAL KNEE REPLACEMENT; URINE RETENTION; VOMITING; WOUND CLOSURE; WOUND INFECTION;

ANESTHETICS, LOCAL; AREA UNDER CURVE; BUPIVACAINE; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HALF-LIFE; HUMANS; LIPOSOMES; MALE; PAIN, POSTOPERATIVE; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84873416661     PISSN: 11732563     EISSN: 11791918     Source Type: Journal    
DOI: 10.1007/s40261-012-0043-z     Document Type: Review

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