Increasing vaginal progesterone gel supplementation after frozen-thawed embryo transfer significantly increases the delivery rate

Reproductive BioMedicine Online

Volumn 26, Issue 2, 2013, Pages 133-137

  Alsbjerg, Birgit ^a   Polyzos, Nikolaos P ^b   Elbaek, Helle Olesen ^a   Povlsen, Betina Boel ^a   Andersen, Claus Yding ^c   Humaidan, Peter ^d  

^a SKIVE REGIONAL HOSPITAL   (Denmark)

^b CENTRE FOR REPRODUCTIVE MEDICINE   (Belgium)

^c Mental Health Services CPH   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

early pregnancy loss; frozen thawed embryo transfer; luteal phase support; progesterone; substituted cycle

Indexed keywords

ESTRADIOL; ESTROFEM; PROGESTERONE;

ADULT; AMENORRHEA; ARTICLE; DELIVERY; DENMARK; DRUG DOSE COMPARISON; EMBRYO TRANSFER; FEMALE; FIRST TRIMESTER PREGNANCY; FROZEN THAWED EMBRYO TRANSFER; HUMAN; INFERTILITY; MAJOR CLINICAL STUDY; OLIGOAMENORRHEA; PREGNANCY RATE; RETROSPECTIVE STUDY; TREATMENT DURATION; TREATMENT OUTCOME;

ADULT; CRYOPRESERVATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO TRANSFER; FEMALE; HUMANS; INFANT, NEWBORN; INFERTILITY, FEMALE; PREGNANCY; PREGNANCY OUTCOME; PROGESTERONE; RETROSPECTIVE STUDIES; VAGINAL CREAMS, FOAMS, AND JELLIES;

EID: 84873411389     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2012.10.012     Document Type: Article

References (17)

1. M.C. Batista, N. Bravo, T.P. Cartledge, D.L. Loriaux, G.R. Merriam, and L.K. Nieman Serum levels of placental protein 14 do not accurately reflect histologic maturation of the endometrium Obstet. Gynecol. 81 1993 439 443
2. C. Bourgain, P. Devroey, L. Van Waesberghe, J. Smitz, and A.C. Van Steirteghem Effects of natural progesterone on the morphology of the endometrium in patients with primary ovarian failure Hum. Reprod. 5 1990 537 543
3. J.H. Check, C. Dietterich, R. Cohen, J.K. Choe, J. Amui, and D. Brasile Increasing the dosage of progesterone (P) supplementation from the mid-luteal phase in women not attaining a mid-luteal homogeneous hyperechogenic (HH) pattern with sonography improves pregnancy rates (PRS) following frozen embryo transfer (ET) Clin. Exp. Obstet. Gynecol. 37 2010 13 14
4. A.I. Csapo, M.O. Pulkkinen, B. Ruttner, J.P. Sauvage, and W.G. Wiest The significance of the human corpus luteum in pregnancy maintenance: I. Preliminary studies Am. J. Obstet. Gynecol. 112 1972 1061 1067
5. K. Elder, and B. Dale In-Vitro Fertilization 2010 Cambridge University Press pp. 198-200. Ref Type: Serial (Book, Monograph)
6. H.M. Fatemi The luteal phase after 3 decades of IVF: what do we know? Reprod. Biomed. Online 19 2009 4331
7. H.M. Fatemi, B. Popovic-Todorovic, E. Papanikolaou, P. Donoso, and P. Devroey An update of luteal phase support in stimulated IVF cycles Hum. Reprod. Update 13 2007 581 590
8. T. Ghobara, and P. Vandekerckhove Cycle regimens for frozen-thawed embryo transfer Cochrane Database Syst. Rev. 2008 CD003414
9. M.G. Hull, P.E. Savage, D.R. Bromham, A.A. Ismail, and A.F. Morris The value of a single serum progesterone measurement in the midluteal phase as a criterion of a potentially fertile cycle ('ovulation') derived from treated and untreated conception cycles Fertil. Steril. 37 1982 355 360
10. B. Lassalle, J. Testart, and J.P. Renard Human embryo features that influence the success of cryopreservation with the use of 1,2 propanediol Fertil. Steril. 44 1985 645 651
11. Y.S. Lin, and C.H. Liu Prediction of early pregnancy outcomes Int. J. Gynaecol. Obstet. 51 1995 33 38
12. R.A. Miles, R.J. Paulson, R.A. Lobo, M.F. Press, L. Dahmoush, and M.V. Sauer Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: a comparative study Fertil. Steril. 62 1994 485 490
13. R. Orvieto, S. Meltcer, M. Volodarski, S. Scharf, J. Rabinson, E. Zohav, E.Y. Anteby, and R. Homburg Luteal phase support for patients undergoing frozen-thawed embryo transfer cycles-the required progesterone dose Clin. Exp. Obstet. Gynecol. 34 2007 25 26
14. N.P. Polyzos, C.I. Messini, E.G. Papanikolaou, D. Mauri, S. Tzioras, A. Badawy, and I.E. Messinis Vaginal progesterone gel for luteal phase support in IVF/ICSI cycles: a meta-analysis Fertil. Steril. 94 2010 2083 2087
15. I. Sudoma, Y. Goncharova, and V. Zukin Optimization of cryocycles by using pinopode detection in patients with multiple implantation failure: preliminary report Reprod. Biomed. Online 22 2011 590 596
16. C. Tomas, B. Alsbjerg, H. Martikainen, and P. Humaidan Pregnancy loss after frozen-embryo transfer-a comparison of three protocols Fertil. Steril 98 2012 1165 1169
17. S. Ziebe, K. Petersen, S. Lindenberg, A.G. Andersen, A. Gabrielsen, and A.N. Andersen Embryo morphology or cleavage stage: how to select the best embryos for transfer after in-vitro fertilization Hum. Reprod. 12 1997 1545 1549