메뉴 건너뛰기




Volumn 28, Issue 2, 2013, Pages 57-66

Efficacy and safety of second-generation long-acting injections in schizophrenia: A meta-analysis of randomized-controlled trials

Author keywords

long acting injections; psychosis; schizophrenia; second generation antipsychotic injections

Indexed keywords

ARIPIPRAZOLE; NEUROLEPTIC AGENT; OLANZAPINE; PALIPERIDONE; PLACEBO; QUETIAPINE; RISPERIDONE; ZIPRASIDONE;

EID: 84873406846     PISSN: 02681315     EISSN: 14735857     Source Type: Journal    
DOI: 10.1097/YIC.0b013e32835b091f     Document Type: Review
Times cited : (80)

References (48)
  • 1
    • 0034776721 scopus 로고    scopus 로고
    • Systematic meta-review of depot antipsychotic drugs for people with schizophrenia
    • Adams CE, Fenton MK, Quraishi S, David AS (2001). Systematic meta-review of depot antipsychotic drugs for people with schizophrenia. Br J Psychiatry 179:290-299.
    • (2001) Br J Psychiatry , vol.179 , pp. 290-299
    • Adams, C.E.1    Fenton, M.K.2    Quraishi, S.3    David, A.S.4
  • 3
    • 84861087821 scopus 로고    scopus 로고
    • Prevalence of concomitant oral antipsychotic drug use among patients treated with long-acting intramuscular antipsychotic medications
    • Aggarwal NK, Sernyak MJ, Rosenheck RA (2012). Prevalence of concomitant oral antipsychotic drug use among patients treated with long-acting intramuscular antipsychotic medications. J Clin Psychopharmacol 32:323-328.
    • (2012) J Clin Psychopharmacol , vol.32 , pp. 323-328
    • Aggarwal, N.K.1    Sernyak, M.J.2    Rosenheck, R.A.3
  • 4
    • 34548560603 scopus 로고    scopus 로고
    • Equivalent switching dose from oral risperidone to risperidone long-acting injection: A 48-week randomized, prospective, single-blind pharmacokinetic study
    • Bai YM, Ting Chen T, Chen JY, Chang WH, Wu B, Hung CH, Kuo Lin W (2007). Equivalent switching dose from oral risperidone to risperidone long-acting injection: a 48-week randomized, prospective, single-blind pharmacokinetic study. J Clin Psychiatry 68:1218-1225.
    • (2007) J Clin Psychiatry , vol.68 , pp. 1218-1225
    • Bai, Y.M.1    Ting Chen, T.2    Chen, J.Y.3    Chang, W.H.4    Wu, B.5    Hung, C.H.6    Kuo Lin, W.7
  • 5
    • 84861807305 scopus 로고    scopus 로고
    • Cost and cost-effectiveness in a randomized trial of long-acting risperidone for schizophrenia
    • Barnett PG, Scott J, Krystal JY, Rosenheck RA (2012). Cost and cost-effectiveness in a randomized trial of long-acting risperidone for schizophrenia. J Clin Psychiatry 73:696-702.
    • (2012) J Clin Psychiatry , vol.73 , pp. 696-702
    • Barnett, P.G.1    Scott, J.2    Krystal, J.Y.3    Rosenheck, R.A.4
  • 6
    • 79960332442 scopus 로고    scopus 로고
    • How do clinical trial participants compare to other patients with schizophrenia?
    • Barnett P, Scott J, Rosenheck R (2011). How do clinical trial participants compare to other patients with schizophrenia? Schizophr Res 130:34-39.
    • (2011) Schizophr Res , vol.130 , pp. 34-39
    • Barnett, P.1    Scott, J.2    Rosenheck, R.3
  • 9
    • 84863009496 scopus 로고    scopus 로고
    • Descriptive analyses of the aripiprazole arm in the risperidone long-acting injectable versus quetiapine relapse prevention trial (ConstaTRE)
    • Epub 2011 August 2
    • De Arce Cordon R, Eding E, Marques-Teixeira J, Milanova V, Rancans E, Schreiner A (2011). Descriptive analyses of the aripiprazole arm in the risperidone long-acting injectable versus quetiapine relapse prevention trial (ConstaTRE). Eur Arch Psychiatry Clin Neurosci 262:139-149. Epub 2011 August 2.
    • (2011) Eur Arch Psychiatry Clin Neurosci , vol.262 , pp. 139-149
    • De Arce Cordon, R.1    Eding, E.2    Marques-Teixeira, J.3    Milanova, V.4    Rancans, E.5    Schreiner, A.6
  • 10
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 11
    • 76749169724 scopus 로고    scopus 로고
    • Biological, clinical, and ethical advances of placebo effects
    • Finniss DG, Kaptchuk TJ, Miller F, Benedetti F (2010). Biological, clinical, and ethical advances of placebo effects. Lancet 375:686-695.
    • (2010) Lancet , vol.375 , pp. 686-695
    • Finniss, D.G.1    Kaptchuk, T.J.2    Miller, F.3    Benedetti, F.4
  • 12
    • 71249128749 scopus 로고    scopus 로고
    • Second-generation antipsychotic long-acting injections: Systematic review
    • Fleischhacker WW (2009). Second-generation antipsychotic long-acting injections: systematic review. Br J Psychiatry Suppl 52:S29-S36.
    • (2009) Br J Psychiatry Suppl , vol.52
    • Fleischhacker, W.W.1
  • 13
    • 77958009877 scopus 로고    scopus 로고
    • Relapse prevention in schizophrenia and schizoaffective disorder with risperidone long-acting injectable vs quetiapine: Results of a long-term, open-label, randomized clinical trial
    • Gaebel W, Schreiner A, Bergmans P, de Arce R, Rouillon F, Cordes J, et al. (2010). Relapse prevention in schizophrenia and schizoaffective disorder with risperidone long-acting injectable vs quetiapine: results of a long-term, open-label, randomized clinical trial. Neuropsychopharmacology 35:2367-2377.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2367-2377
    • Gaebel, W.1    Schreiner, A.2    Bergmans, P.3    De Arce, R.4    Rouillon, F.5    Cordes, J.6
  • 14
    • 74449091850 scopus 로고    scopus 로고
    • Paliperidone palmitate maintenance treatment in delaying the time-to-relapse in patients with schizophrenia: A randomized, double-blind, placebo-controlled study
    • Hough D, Gopal S, Vijapurkar U, Lim P, Morozova M, Eerdekens M (2010). Paliperidone palmitate maintenance treatment in delaying the time-to-relapse in patients with schizophrenia: a randomized, double-blind, placebo-controlled study. Schizophr Res 116:107-117.
    • (2010) Schizophr Res , vol.116 , pp. 107-117
    • Hough, D.1    Gopal, S.2    Vijapurkar, U.3    Lim, P.4    Morozova, M.5    Eerdekens, M.6
  • 15
    • 33749321169 scopus 로고    scopus 로고
    • Randomized controlled trial of the effect on quality of life of second-vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    • Jones PB, Barnes TR, Davies L, Dunn G, Lloyd H, Hayhurst KP, et al. (2006). Randomized controlled trial of the effect on quality of life of second-vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Arch Gen Psychiatry 63:1079-1087.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1079-1087
    • Jones, P.B.1    Barnes, T.R.2    Davies, L.3    Dunn, G.4    Lloyd, H.5    Hayhurst, K.P.6
  • 17
    • 40949142200 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: An open randomised clinical trial
    • Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, et al. (2008). Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Lancet 371:1085-1097.
    • (2008) Lancet , vol.371 , pp. 1085-1097
    • Kahn, R.S.1    Fleischhacker, W.W.2    Boter, H.3    Davidson, M.4    Vergouwe, Y.5    Keet, I.P.6
  • 18
    • 0038149626 scopus 로고    scopus 로고
    • Long-acting injectable risperidone: Efficacy and safety of the first long-acting atypical antipsychotic
    • Kane JM, Eerdekens M, Lindenmayer JP, Keith SJ, Lesem M, Karcher K (2003a). Long-acting injectable risperidone: efficacy and safety of the first long-acting atypical antipsychotic. Am J Psychiatry 160:1125-1132.
    • (2003) Am J Psychiatry , vol.160 , pp. 1125-1132
    • Kane, J.M.1    Eerdekens, M.2    Lindenmayer, J.P.3    Keith, S.J.4    Lesem, M.5    Karcher, K.6
  • 19
    • 1542776092 scopus 로고    scopus 로고
    • The expert consensus guideline series. Optimizing pharmacologic treatment of psychotic disorders. Introduction: Methods, commentary, and summary
    • Kane JM, Leucht S, Carpenter D, Docherty JP (2003b). The expert consensus guideline series. Optimizing pharmacologic treatment of psychotic disorders. Introduction: methods, commentary, and summary. J Clin Psychiatry 64 (Suppl 12):5-19.
    • (2003) J Clin Psychiatry , vol.64 , Issue.SUPPL. 12 , pp. 5-19
    • Kane, J.M.1    Leucht, S.2    Carpenter, D.3    Docherty, J.P.4
  • 20
    • 75749098515 scopus 로고    scopus 로고
    • Olanzapine long-acting injection: A 24-week, randomized, double-blind trial of maintenance treatment in patients with schizophrenia
    • Kane JM, Detke HC, Naber D, Sethuraman G, Lin DY, Bergstrom RF, McDonnell D (2010). Olanzapine long-acting injection: a 24-week, randomized, double-blind trial of maintenance treatment in patients with schizophrenia. Am J Psychiatry 167:181-189.
    • (2010) Am J Psychiatry , vol.167 , pp. 181-189
    • Kane, J.M.1    Detke, H.C.2    Naber, D.3    Sethuraman, G.4    Lin, D.Y.5    Bergstrom, R.F.6    McDonnell, D.7
  • 21
    • 34547615756 scopus 로고    scopus 로고
    • Long-acting injectable risperidone v. olanzapine tablets for schizophrenia or schizoaffective disorder. Randomised, controlled, open-label study
    • Keks NA, Ingham M, Khan A, Karcher K (2007). Long-acting injectable risperidone v. olanzapine tablets for schizophrenia or schizoaffective disorder. Randomised, controlled, open-label study. Br J Psychiatry 191:131-139.
    • (2007) Br J Psychiatry , vol.191 , pp. 131-139
    • Keks, N.A.1    Ingham, M.2    Khan, A.3    Karcher, K.4
  • 22
    • 77954142687 scopus 로고    scopus 로고
    • Progressive lateral ventricular enlargement in schizophrenia: A meta-analysis of longitudinal MRI studies
    • Kempton MJ, Stahl D, Williams SC, DeLisi LE (2010). Progressive lateral ventricular enlargement in schizophrenia: a meta-analysis of longitudinal MRI studies Schizophr Res 120:54-62.
    • (2010) Schizophr Res , vol.120 , pp. 54-62
    • Kempton, M.J.1    Stahl, D.2    Williams, S.C.3    Delisi, L.E.4
  • 23
    • 33744907008 scopus 로고    scopus 로고
    • Size of treatment effects and their importance to clinical research and practice
    • Kraemer HC, Kupfer DJ (2006). Size of treatment effects and their importance to clinical research and practice. Biol Psychiatry 59:990-996.
    • (2006) Biol Psychiatry , vol.59 , pp. 990-996
    • Kraemer, H.C.1    Kupfer, D.J.2
  • 24
    • 77953541809 scopus 로고    scopus 로고
    • Paliperidone palmitate, a potential long-acting treatment for patients with schizophrenia. Results of a randomized, double-blind, placebo-controlled efficacy and safety study
    • Kramer M, Litman R, Hough D, Lane R, Lim P, Liu Y, Eerdekens M (2010). Paliperidone palmitate, a potential long-acting treatment for patients with schizophrenia. Results of a randomized, double-blind, placebo-controlled efficacy and safety study. Int J Neuropsychopharmacol 13:635-647.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 635-647
    • Kramer, M.1    Litman, R.2    Hough, D.3    Lane, R.4    Lim, P.5    Liu, Y.6    Eerdekens, M.7
  • 25
    • 45249085941 scopus 로고    scopus 로고
    • An 8-week, double-blind, randomized, placebo-controlled study of olanzapine long-acting injection in acutely ill patients with schizophrenia
    • Lauriello J, Lambert T, Andersen S, Lin D, Taylor CC, McDonnell D (2008). An 8-week, double-blind, randomized, placebo-controlled study of olanzapine long-acting injection in acutely ill patients with schizophrenia. J Clin Psychiatry 69:790-799.
    • (2008) J Clin Psychiatry , vol.69 , pp. 790-799
    • Lauriello, J.1    Lambert, T.2    Andersen, S.3    Lin, D.4    Taylor, C.C.5    McDonnell, D.6
  • 26
    • 62849099049 scopus 로고    scopus 로고
    • How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials
    • Leucht S, Arbter D, Engel RR, Kissling W, Davis JM (2009a). How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials. Mol Psychiatry 14:429-447.
    • (2009) Mol Psychiatry , vol.14 , pp. 429-447
    • Leucht, S.1    Arbter, D.2    Engel, R.R.3    Kissling, W.4    Davis, J.M.5
  • 27
    • 58049157203 scopus 로고    scopus 로고
    • Second-generation versus first-generation antipsychotic drugs for schizophrenia: A meta-analysis
    • Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM (2009b). Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet 373:31-41.
    • (2009) Lancet , vol.373 , pp. 31-41
    • Leucht, S.1    Corves, C.2    Arbter, D.3    Engel, R.R.4    Li, C.5    Davis, J.M.6
  • 28
    • 64349118890 scopus 로고    scopus 로고
    • Definitions of response and remission in schizophrenia: Recommendations for their use and their presentation
    • Leucht S, Davis JM, Engel RR, Kissling W, Kane JM (2009c). Definitions of response and remission in schizophrenia: recommendations for their use and their presentation. Acta Psychiatr Scand Suppl 7-14.
    • (2009) Acta Psychiatr Scand Suppl , pp. 7-14
    • Leucht, S.1    Davis, J.M.2    Engel, R.R.3    Kissling, W.4    Kane, J.M.5
  • 29
    • 60349086480 scopus 로고    scopus 로고
    • A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia
    • Leucht S, Komossa K, Rummel-Kluge C, Corves C, Hunger H, Schmid F, et al. (2009d). A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia. Am J Psychiatry 166:152-163.
    • (2009) Am J Psychiatry , vol.166 , pp. 152-163
    • Leucht, S.1    Komossa, K.2    Rummel-Kluge, C.3    Corves, C.4    Hunger, H.5    Schmid, F.6
  • 30
    • 79952312699 scopus 로고    scopus 로고
    • Oral versus depot antipsychotic drugs for schizophrenia-a critical systematic review and meta-analysis of randomised long-term trials
    • Leucht C, Heres S, Kane JM, Kissling W, Davis JM, Leucht S (2011). Oral versus depot antipsychotic drugs for schizophrenia-a critical systematic review and meta-analysis of randomised long-term trials. Schizophr Res 127:83-92.
    • (2011) Schizophr Res , vol.127 , pp. 83-92
    • Leucht, C.1    Heres, S.2    Kane, J.M.3    Kissling, W.4    Davis, J.M.5    Leucht, S.6
  • 31
    • 0037712923 scopus 로고    scopus 로고
    • Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: A 52-week randomized trial of clozapine vs chlorpromazine
    • Lieberman JA, Phillips M, Gu H, Stroup S, Zhang P, Kong L, et al. (2003). Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs chlorpromazine. Neuropsychopharmacology 28:995-1003.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 995-1003
    • Lieberman, J.A.1    Phillips, M.2    Gu, H.3    Stroup, S.4    Zhang, P.5    Kong, L.6
  • 34
    • 78650058642 scopus 로고    scopus 로고
    • A prospective study comparing the long-term effectiveness of injectable risperidone long-acting therapy and oral aripiprazole in patients with schizophrenia
    • Macfadden W, Ma YW, Thomas Haskins J, Bossie CA, Alphs L (2010). A prospective study comparing the long-term effectiveness of injectable risperidone long-acting therapy and oral aripiprazole in patients with schizophrenia. Psychiatry (Edgmont) 7:23-31.
    • (2010) Psychiatry (Edgmont) , vol.7 , pp. 23-31
    • MacFadden, W.1    Ma, Y.W.2    Thomas Haskins, J.3    Bossie, C.A.4    Alphs, L.5
  • 36
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:332-336.
    • (2009) BMJ , vol.339 , pp. 332-336
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 37
    • 77955716709 scopus 로고    scopus 로고
    • A controlled, evidence-based trial of paliperidone palmitate, a long-acting injectable antipsychotic, in schizophrenia
    • Nasrallah HA, Gopal S, Gassmann-Mayer C, Quiroz JA, Lim P, Eerdekens M, et al. (2010). A controlled, evidence-based trial of paliperidone palmitate, a long-acting injectable antipsychotic, in schizophrenia. Neuropsychopharmacology 35:2072-2082.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2072-2082
    • Nasrallah, H.A.1    Gopal, S.2    Gassmann-Mayer, C.3    Quiroz, J.A.4    Lim, P.5    Eerdekens, M.6
  • 38
    • 16344377056 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of patients on risperidone depot
    • Nesvag R, Tanum L (2005). Therapeutic drug monitoring of patients on risperidone depot. Nord J Psychiatry 59:51-55.
    • (2005) Nord J Psychiatry , vol.59 , pp. 51-55
    • Nesvag, R.1    Tanum, L.2
  • 39
    • 0000519782 scopus 로고
    • A fail-safe N for effect size in meta-analysis
    • Orwin R (1983). A fail-safe N for effect size in meta-analysis. J Educ Stat 8:157-159.
    • (1983) J Educ Stat , vol.8 , pp. 157-159
    • Orwin, R.1
  • 40
    • 77952388203 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study to assess the efficacy and safety of 3 doses of paliperidone palmitate in adults with acutely exacerbated schizophrenia
    • Pandina GJ, Lindenmayer JP, Lull J, Lim P, Gopal S, Herben V, et al. (2010). A randomized, placebo-controlled study to assess the efficacy and safety of 3 doses of paliperidone palmitate in adults with acutely exacerbated schizophrenia. J Clin Psychopharmacol 30:235-244.
    • (2010) J Clin Psychopharmacol , vol.30 , pp. 235-244
    • Pandina, G.J.1    Lindenmayer, J.P.2    Lull, J.3    Lim, P.4    Gopal, S.5    Herben, V.6
  • 41
    • 77952364788 scopus 로고    scopus 로고
    • Prenatal and postpartum depression in fathers and its association with maternal depression: A meta-analysis
    • Paulson JF, Bazemore SD (2010). Prenatal and postpartum depression in fathers and its association with maternal depression: a meta-analysis. JAMA 303:1961-1969.
    • (2010) JAMA , vol.303 , pp. 1961-1969
    • Paulson, J.F.1    Bazemore, S.D.2
  • 43
    • 17644371975 scopus 로고    scopus 로고
    • How representative of everyday clinical populations are schizophrenia patients enrolled in clinical trials?
    • Riedel M, Strassnig M, Muller N, Zwack P, Moller HJ (2005). How representative of everyday clinical populations are schizophrenia patients enrolled in clinical trials? Eur Arch Psychiatry Clin Neurosci 255:143-148.
    • (2005) Eur Arch Psychiatry Clin Neurosci , vol.255 , pp. 143-148
    • Riedel, M.1    Strassnig, M.2    Muller, N.3    Zwack, P.4    Moller, H.J.5
  • 44
    • 0345293130 scopus 로고    scopus 로고
    • Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: A randomized controlled trial
    • Rosenheck R, Perlick D, Bingham S, Liu-Mares W, Collins J, Warren S, et al. (2003). Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial. JAMA 290:2693-2702.
    • (2003) JAMA , vol.290 , pp. 2693-2702
    • Rosenheck, R.1    Perlick, D.2    Bingham, S.3    Liu-Mares, W.4    Collins, J.5    Warren, S.6
  • 46
    • 84555186903 scopus 로고    scopus 로고
    • Second-generation antipsychotic drugs and extrapyramidal side effects: A systematic review and meta-analysis of head-to-head comparisons
    • Rummel-Kluge C, Komossa K, Schwarz S, Hunger H, Schmid F, Kissling W, et al. (2012). Second-generation antipsychotic drugs and extrapyramidal side effects: a systematic review and meta-analysis of head-to-head comparisons. Schizophr Bull 38:167-177.
    • (2012) Schizophr Bull , vol.38 , pp. 167-177
    • Rummel-Kluge, C.1    Komossa, K.2    Schwarz, S.3    Hunger, H.4    Schmid, F.5    Kissling, W.6
  • 47
    • 0034685429 scopus 로고    scopus 로고
    • Meta-analysis of observational studies in epidemiology: A proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group
    • Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al. (2000). Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283:2008-2012.
    • (2000) JAMA , vol.283 , pp. 2008-2012
    • Stroup, D.F.1    Berlin, J.A.2    Morton, S.C.3    Olkin, I.4    Williamson, G.D.5    Rennie, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.