SCF Fbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression

Nature Cell Biology

Volumn 15, Issue 2, 2013, Pages 179-188

  Werner, Achim ^a   Disanza, Andrea ^b   Reifenberger, Nina ^a   Habeck, Gregor ^a   Becker, Janina ^a   Calabrese, Matthew ^c   Urlaub, Henning ^d,e   Lorenz, Holger ^a   Schulman, Brenda ^c   Scita, Giorgio ^b,f   Melchior, Frauke ^a  

^a GERMAN CANCER RESEARCH CENTER   (Germany)

^b FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^e UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^f UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 8; PROTEASOME; SCF PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; EPS8 PROTEIN, HUMAN; EPS8 PROTEIN, MOUSE; F BOX PROTEIN; FBXW5 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CELL CORTEX; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL LEVEL; CELL MEMBRANE; CELL SHAPE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINESIS; ENZYME DEGRADATION; HUMAN; MEMBRANE STRUCTURE; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN DEGRADATION; PROTEIN STABILITY; REGULATORY MECHANISM; ACTIN FILAMENT; ANIMAL; BINDING COMPETITION; CELL STRAIN HEK293; G2 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSFECTION; GENETICS; HALF LIFE TIME; HELA CELL; METABOLISM; METAPHASE; MOUSE MUTANT; PROTEIN BINDING; RNA INTERFERENCE; TIME; UBIQUITINATION; VIDEO MICROSCOPY;

ACTIN CYTOSKELETON; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING, COMPETITIVE; CELL SHAPE; F-BOX PROTEINS; G2 PHASE CELL CYCLE CHECKPOINTS; HALF-LIFE; HEK293 CELLS; HELA CELLS; HUMANS; METAPHASE; MICE; MICE, KNOCKOUT; MICROSCOPY, VIDEO; MITOSIS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STABILITY; PROTEOLYSIS; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; UBIQUITINATION;

MLCS; MLOWN;

EID: 84873406469     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2661     Document Type: Article

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