A nanostructured liquid crystalline formulation of 20(S)-protopanaxadiol with improved oral absorption

Fitoterapia

Volumn 84, Issue 1, 2013, Pages 64-71

  Jin, Xin ^a,b,c   Zhang, Zhen Hai ^a   Li, Song Lin ^c   Sun, E ^a   Tan, Xiao Bin ^a   Song, Jie ^a   Jia, Xiao Bin ^a,b  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c Jiangsu Province Academy of Traditional Chinese Medicine   (China)

Author keywords

20(S) protopanaxadiol; Bioavailability; Caco 2 cell monolayer; Cubosome; Rat intestinal perfusion model

Indexed keywords

NANOCARRIER; PROTOPANAXADIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; INTESTINE PERFUSION; MALE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY; ZETA POTENTIAL;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; HALF-LIFE; HUMANS; INTESTINES; LIQUID CRYSTALS; MALE; MOLECULAR STRUCTURE; NANOSTRUCTURES; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SAPOGENINS;

EID: 84873394258     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.09.013     Document Type: Article

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