Isolation of cells from the lower airways in infants with wheeze by sputum induction

European Respiratory Journal

Volumn 41, Issue 2, 2013, Pages 483-485

  Gaillard, Erol A ^a   Grigg, Jonathan ^b   Tellabati, Ananth ^a   McNally, Teresa ^a   Whittaker, Amy ^c   Beardsmore, Caroline S ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c ST GEORGE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID;

ADVERSE OUTCOME; CELL ISOLATION; CELL TYPE; CHILD; ECZEMA; EPITHELIUM CELL; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; INFANT; INFLAMMATORY CELL; LETTER; LEUKOCYTE DIFFERENTIAL COUNT; LOWER RESPIRATORY TRACT; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL COUNT; PATIENT SAFETY; PRESCHOOL CHILD; PRIORITY JOURNAL; SAMPLING; SPUTUM EXAMINATION; SPUTUM INDUCTION; WHEEZING;

ADRENAL CORTEX HORMONES; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFLAMMATION; MALE; MICROSCOPY; NEBULIZERS AND VAPORIZERS; PILOT PROJECTS; RESPIRATORY SOUNDS; RESPIRATORY SYSTEM; SPUTUM; SUCTION;

EID: 84873348742     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00160412     Document Type: Letter

References (10)

1. Kuehni CE, Davis A, Brooke AM, et al. Are all wheezing disorders in very young (preschool) children increasing in prevalenceLancet 2001; 357: 1821-1825.
2. Martinez FD, Wright AL, Taussig LM, et al. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 1995; 332: 133-138.
3. Henderson J, Granell R, Heron J, et al. Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax 2008; 63: 974-980.
4. Saglani S, Payne DN, Zhu J, et al. Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers. Am J Respir Crit Care Med 2007; 176: 858-864.
5. Lex C, Payne DN, Zacharasiewicz A, et al. Sputum induction in children with difficult asthma: safety, feasibility, and inflammatory cell pattern. Pediatr Pulmonol 2005; 39: 318-324.
6. Mussaffi H, Fireman EM, Mei-Zahav M, et al. Induced sputum in the very young: A new key to infection and inflammation. Chest 2008; 133: 176-182.
7. Zar HJ, Tannenbaum E, Apolles P, et al. Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South Africa. Arch Dis Child 2000; 82: 305-308.
8. Yamada Y, Yoshihara S, Arisaka O. Creola bodies in wheezing infants predict the development of asthma. Pediatr Allergy Immunol 2004; 15: 159-162.
9. Pavord ID, Pizzichini MM, Pizzichini E, et al. The use of induced sputum to investigate airway inflammation. Thorax 1997; 52: 498-501.
10. Brand PL, Baraldi E, Bisgaard H, et al. Definition, assessment and treatment of wheezing disorders in preschool children: An evidence-based approach. Eur Respir J 2008; 32: 1096-1110.