The role of adipose tissue in insulin resistance in women of African ancestry

Journal of Obesity

Volumn 2013, Issue , 2013, Pages

  Goedecke, Julia H ^a,b   Levitt, Naomi S ^c   Evans, Juliet ^d   Ellman, Nicole ^b   Hume, David John ^b   Kotze, Liske ^b   Tootla, Mehreen ^b   Victor, Hendriena ^b   Keswell, Dheshnie ^b  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d WESTERN CAPE DEPARTMENT OF HEALTH   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GLUCOCORTICOID; INTERLEUKIN 18; INTERLEUKIN 6; SEX HORMONE;

ADIPOGENESIS; ADIPOSE TISSUE; AFRICAN AMERICAN; BODY FAT DISTRIBUTION; ESTRADIOL BLOOD LEVEL; ESTROGEN BLOOD LEVEL; ETHNICITY; EUROPEAN AMERICAN; FEMALE; HORMONE METABOLISM; HUMAN; HYPOXEMIA; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; LIPOLYSIS; OBESITY; OXIDATIVE STRESS; POSTMENOPAUSE; PREMENOPAUSE; RACE; REVIEW; AFRICA; BODY MASS; CELL HYPOXIA; ETHNOLOGY; METABOLISM; NEGRO; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADIPOGENESIS; ADIPOSE TISSUE; AFRICA; AFRICAN CONTINENTAL ANCESTRY GROUP; BODY FAT DISTRIBUTION; BODY MASS INDEX; CELL HYPOXIA; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOCORTICOIDS; GONADAL STEROID HORMONES; HUMANS; INFLAMMATION; INSULIN RESISTANCE; LIPOLYSIS; OBESITY; OXIDATIVE STRESS;

MLCS; MLOWN;

EID: 84873343330     PISSN: 20900708     EISSN: 20900716     Source Type: Journal    
DOI: 10.1155/2013/952916     Document Type: Review

References (86)

1. Peer N., Steyn K., Lombard C., Rising diabetes prevalence among urban-dwelling black South Africans. PLoS ONE 2012 7, article e43336
2. Duke C. M. P., Plowden T. C., Armstrong A. Y., Disparate cardiovascular and diabetic outcomes in young adult black women: studies from across the Globe. Current Cardiovascular Risk Reports 2012 6 251 258
3. Joubert J., Norman R., Bradshaw D., Goedecke J. H., Steyn N. P., Puoane T., Estimating the burden of disease attributable to excess body weight in South Africa in 2000. South African Medical Journal 2007 97 8 683 690 2-s2.0-38449110519
4. Goedecke J. H., Dave J. A., Faulenbach M. V., Utzschneider K. M., Lambert E. V., West S., Collins M., Olsson T., Walker B. R., Seckl J. R., Kahn S. E., Levitt N. S., Insulin response in relation to insulin sensitivity: an appropriate beta-cell response in black South African women. Diabetes Care 2009 32 5 860 865
5. Lovejoy J. C., De La Bretonne J. A., Klemperer M., Tulley R., Abdominal fat distribution and metabolic risk factors: effects of race. Metabolism 1996 45 9 1119 1124 2-s2.0-0029761802 10.1016/S0026-0495(96)90011-6 (Pubitemid 26300311)
6. Van Der Merwe M. T., Crowther N. J., Schlaphoff G. P., Boyd I. H., Gray I. P., Joffe B. I., Lönnroth P. N., Lactate and glycerol release from the subcutaneous adipose tissue of obese urban women from South Africa; important metabolic implications. Journal of Clinical Endocrinology and Metabolism 1998 83 11 4084 4091 2-s2.0-0031763319 (Pubitemid 28513600)
7. Haffner S. M., D'Agostino R., Saad M. F., Rewers M., Mykkänen L., Selby J., Howard G., Savage P. J., Hamman R. F., Wagenknecht L. E., Bergman R. N., Increased insulin resistance and insulin secretion in nondiabetic African-Americans and Hispanics compared with non-Hispanic whites: The Insulin Resistance Atherosclerosis Study. Diabetes 1996 45 6 742 748 2-s2.0-0030013917
8. Goran M. I., Ethnic-specific pathways to obesity-related disease: The Hispanic vs. African-American paradox. Obesity 2008 16 12 2561 2565 2-s2.0-58149308506 10.1038/oby.2008.423
9. Boorsma W., Snijder M. B., Nijpels G., Guidone C., Favuzzi A. M. R., Mingrone G., Kostense P. J., Heine R. J., Dekker J. M., Body composition, insulin sensitivity, and cardiovascular disease profile in healthy Europeans. Obesity 2008 16 12 2696 2701 2-s2.0-58149311084 10.1038/oby.2008.433
10. Preis S. R., Massaro J. M., Robins S. J., Hoffmann U., Vasan R. S., Irlbeck T., Meigs J. B., Sutherland P., D'Agostino R. B., O'Donnell C. J., Fox C. S., Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the framingham heart study. Obesity 2010 18 11 2191 2198 2-s2.0-78049308422 10.1038/oby.2010.59
11. Shay C. M., Carnethon M. R., Church T. R., Lower extremity fat mass is associated with insulin resistance in overweight and obese individuals: The CARDIA Study. Obesity 2011 19 2248 2253
12. Goedecke J. H., Levitt N. S., Lambert E. V., Utzschneider K. M., Faulenbach M. V., Dave J. A., West S., Victor H., Evans J., Olsson T., Walker B. R., Seckl J. R., Kahn S. E., Differential effects of abdominal adipose tissue distribution on insulin sensitivity in black and white South African women. Obesity 2009 17 8 1506 1512 2-s2.0-67749101774 10.1038/oby.2009.73
13. Lovejoy J. C., Smith S. R., Rood J. C., Comparison of regional fat distribution and health risk factors in middle-aged white and African American women: the healthy transitions study. Obesity Research 2001 9 1 10 16 2-s2.0-0035222314 (Pubitemid 33603825)
14. Goedecke J. H., Evans J., Keswell D., Reduced gluteal expression of adipogenic and lipogenic genes in black South African women is associated with obesity-related insulin resistance. The Journal of Clinical Endocrinology & Metabolism 2011 96 E2029 E2033
15. Richelsen B., Pedersen S. B., Moller-Pedersen T., Bak J. F., Regional differences in triglyceride breakdown in human adipose tissue: effects of catecholamines, insulin, and prostaglandin E2. Metabolism 1991 40 9 990 996 2-s2.0-0025915245 10.1016/0026-0495(91)90078-B
16. Goedecke J. H., Wake D. J., Levitt N. S., Lambert E. V., Collins M. R., Morton N. M., Andrew R., Seckl J. R., Walker B. R., Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women. Clinical Endocrinology 2006 65 1 81 87 2-s2.0-33745186881 10.1111/j.1365-2265. 2006.02552.x
17. Gauthier M. S., O'Brien E. L., Bigornia S., Mott M., Cacicedo J. M., Xu X. J., Gokce N., Apovian C., Ruderman N., Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans. Biochemical and Biophysical Research Communications 2011 404 1 382 387 2-s2.0-78650964142 10.1016/j.bbrc.2010.11.127
18. Alvehus M., Burén J., Sjöström M., Goedecke J., Olsson T., The human visceral fat depot has a unique inflammatory profile. Obesity 2010 18 5 879 883 2-s2.0-77951666491 10.1038/oby.2010.22
19. Wilding J. P. H., The importance of free fatty acids in the development of Type 2 diabetes. Diabetic Medicine 2007 24 9 934 945 2-s2.0-34548186474 10.1111/j.1464-5491.2007.02186.x (Pubitemid 47304378)
20. Walker G. E., Marzullo P., Verti B., Guzzaloni G., Maestrini S., Zurleni F., Liuzzi A., Di Blasio A. M., Subcutaneous abdominal adipose tissue subcompartments: potential role in rosiglitazone effects. Obesity 2008 16 9 1983 1991 2-s2.0-50649102114 10.1038/oby.2008.326
21. Monzon J. R., Basile R., Heneghan S., Udupi V., Green A., Lipolysis in adipocytes isolated from deep and superficial subcutaneous adipose tissue. Obesity Research 2002 10 266 269 (Pubitemid 135688234)
22. Tordjman J., Divoux A., Prifti E., Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity. Journal of Hepatology 2012 56 1152 1158
23. Lundbom J., Hakkarainen A., Lundbom N., Taskinen M. R., Deep subcutaneous adipose tissue is more saturated than superficial subcutaneous adipose tissue. International Journal of Obesity. In press
24. Votruba S. B., Jensen M. D., Sex differences in abdominal, gluteal, and thigh LPL activity. American Journal of Physiology-Endocrinology and Metabolism 2007 292 6 E1823 E1828 2-s2.0-34447555823 10.1152/ajpendo.00601.2006 (Pubitemid 47084719)
25. Manolopoulos K. N., Karpe F., Frayn K. N., Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo. Diabetologia 2012 55 3029 3037
26. Tittelbach T. J., Berman D. M., Nicklas B. J., Ryan A. S., Goldberg A. P., Racial differences in adipocyte size and relationship to the metabolic syndrome in obese women. Obesity Research 2004 12 6 990 998 2-s2.0-4644245971 (Pubitemid 41202401)
27. Manolopoulos K. N., Karpe F., Frayn K. N., Gluteofemoral body fat as a determinant of metabolic health. International Journal of Obesity 2010 34 6 949 959 2-s2.0-77953612080 10.1038/ijo.2009.286
28. Pinnick K. E., Neville M. J., Fielding B. A., Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans. Diabetes 2012 61 1399 1403
29. Toth M. J., Tchernof A., Sites C. K., Poehlman E. T., Effect of menopausal status on body composition and abdominal fat distribution. International Journal of Obesity 2000 24 2 226 231 2-s2.0-0033962727 (Pubitemid 30107573)
30. Salpeter S. R., Walsh J. M. E., Ormiston T. M., Greyber E., Buckley N. S., Salpeter E. E., Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes, Obesity and Metabolism 2006 8 5 538 554 2-s2.0-33746862148 10.1111/j.1463-1326.2005. 00545.x (Pubitemid 44184248)
31. Casazza K., Goran M. I., Gower B. A., Associations among insulin, estrogen, and fat mass gain over the pubertal transition in African-American and european-american girls. Journal of Clinical Endocrinology and Metabolism 2008 93 7 2610 2615 2-s2.0-47549100208 10.1210/jc.2007-2776 (Pubitemid 352008527)
32. Randolph J. F., Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal status. The Journal of Clinical Endocrinology & Metabolism 2003 88 1516 1522
33. Setiawan V. W., Haiman C. A., Stanczyk F. Z., Le Marchand L., Henderson B. E., Racial/ethnic differences in postmenopausal endogenous hormones: The Multiethnic Cohort Study. Cancer Epidemiology Biomarkers and Prevention 2006 15 10 1849 1855 2-s2.0-33750510871 10.1158/1055-9965.EPI-06-0307 (Pubitemid 44664259)
34. Kim C., Golden S. H., Mather K. J., Racial/ethnic differences in sex hormone levels among postmenopausal women in the diabetes prevention program. The Journal of Clinical Endocrinology & Metabolism 2012 97 4051 4060
35. Enmark E., Gustafsson J. Å., Oestrogen receptors-an overview. Journal of Internal Medicine 1999 246 2 133 138 2-s2.0-0032813510 10.1046/j.1365-2796.1999.00545.x (Pubitemid 29378917)
36. Naaz A., Zakroczymski M., Heine P., Taylor J., Saunders P., Lubahn D., Cooke P. S., Effect of ovariectomy on adipose tissue of mice in the absence of estrogen receptor alpha (ER α): a potential role for estrogen receptor beta (ER β). Hormone and Metabolic Research 2002 34 11-12 758 763 2-s2.0-0036875643 10.1055/s-2002-38259 (Pubitemid 36398720)
37. Bryzgalova G., Gao H., Ahren B., Zierath J. R., Galuska D., Steiler T. L., Dahlman-Wright K., Nilsson S., Gustafsson J. Å., Efendic S., Khan A., Evidence that oestrogen receptor- α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver. Diabetologia 2006 49 3 588 597 2-s2.0-33244495940 10.1007/s00125-005-0105-3 (Pubitemid 43277883)
38. Boscaro M., Barzon L., Fallo F., Sonino N., Cushing's syndrome. Lancet 2001 357 9258 783 791 2-s2.0-0035835971 10.1016/S0140-6736(00)04172-6 (Pubitemid 32217692)
39. Rask E., Olsson T., Söderberg S., Tissue-specific dysregulation of cortisol metabolism in human obesity. The Journal of Clinical Endocrinology & Metabolism 2001 86 1418 1421 (Pubitemid 32323037)
40. Masuzaki H., Paterson J., Shinyama H., A transgenic model of visceral obesity and the metabolic syndrome. Science 2001 294 2166 2170 (Pubitemid 33150673)
41. Morton N. M., Ramage L., Seckl J. R., Down-regulation of adipose 11 β -hydroxysteroid dehydrogenase type 1 by high-fat feeding in mice: a potential adaptive mechanism counteracting metabolic disease. Endocrinology 2004 145 6 2707 2712 2-s2.0-2542481820 10.1210/en.2003-1674 (Pubitemid 38686218)
42. Rask E., Walker B. R., Söderberg S., Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11hydroxysteroid dehydrogenase type 1 activity. The Journal of Clinical Endocrinology & Metabolism 2002 87 3330 3336 (Pubitemid 34816385)
43. Albu J. B., Curi M., Shur M., Murphy L., Matthews D. E., Pi-Sunyer F. X., Systemic resistance to the antilipolytic effect of insulin in black and white women with visceral obesity. American Journal of Physiology 1999 277 3 E551 E560 2-s2.0-0032853590 (Pubitemid 29458217)
44. Racette S. B., Horowitz J. F., Mittendorfer B., Klein S., Racial differences in lipid metabolism in women with abdominal obesity. American Journal of Physiology 2000 279 3 R944 R950 2-s2.0-0033835869
45. Barakat H., Hickner R. C., Privette J., Bower J., Hao E., Udupi V., Green A., Pories W., MacDonald K., Differences in the lipolytic function of adipose tissue preparations from Black American and Caucasian women. Metabolism 2002 51 11 1514 1518 2-s2.0-0036835417
46. Fried S. K., Tittelbach T., Blumenthal J., Sreenivasan U., Robey L., Yi J., Khan S., Hollender C., Ryan A. S., Goldberg A. P., Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women. Journal of Lipid Research 2010 51 5 1193 1200 2-s2.0-77951057041 10.1194/jlr.P000935
47. Buthelezi E. P., Van Der Merwe M. T., Lönnroth P. N., Gray I. P., Crowther N. J., Ethnic differences in the responsiveness of adipocyte lipolytic activity to insulin. Obesity Research 2000 8 2 171 178 2-s2.0-0034151886
48. Goedecke J. H., Utzschneider K., Faulenbach M. V., Ethnic differences in serum lipoproteins and their determinants in South African women. Metabolism-Clinical and Experimental 2010 59 1341 1350
49. Festa A., D'Agostino R., Howard G., Mykkänen L., Tracy R. P., Haffner S. M., Chronic subclinical inflammation as part of the insulin resistance syndrome: The Insulin Resistance Atherosclerosis Study (IRAS). Circulation 2000 102 1 42 47 2-s2.0-0034604248 (Pubitemid 30430551)
50. Hyatt T. C., Phadke R. P., Hunter G. R., Insulin sensitivity in African-American and white women: association with inflammation. Obesity 2009 2 276 282
51. Zirlik A., Abdullah S. M., Gerdes N., Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study. Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 2043 2049 (Pubitemid 47312316)
52. Ferris W. F., Naran N. H., Crowther N. J., The relationship between insulin sensitivity and serum adiponectin levels in three population groups. Hormone and Metabolic Research 2005 37 695 701 (Pubitemid 41810493)
53. Hulver M. W., Saleh O., MacDonald K. G., Pories W. J., Barakat H. A., Ethnic differences in adiponectin levels. Metabolism 2004 53 1 1 3 2-s2.0-0346685847 10.1016/j.metabol.2003.07.002 (Pubitemid 38071928)
54. Gustafson B., Gogg S., Hedjazifar S., Inflammation and impaired adipogenesis in hypertrophic obesity in man. American Journal of Physiology 2009 297 E999 E1003
55. Ali A. T., Penny C. B., Paiker J. E., Van Niekerk C., Smit A., Ferris W. F., Crowther N. J., Alkaline phosphatase is involved in the control of adipogenesis in the murine preadipocyte cell line, 3T3-L1. Clinica Chimica Acta 2005 354 1-2 101 109 2-s2.0-14644399752 10.1016/j.cccn.2004.11.026 (Pubitemid 40320679)
56. Smith L. M., Yao-Borengasser A., Starks T., Tripputi M., Kern P. A., Rasouli N., Insulin resistance in African-American and Caucasian women: differences in lipotoxicity, adipokines, and gene expression in adipose tissue and muscle. Journal of Clinical Endocrinology and Metabolism 2010 95 9 4441 4448 2-s2.0-77956562860 10.1210/jc.2010-0017
57. van Tienen F. H. J., van der Kallen C. J., Lindsey P. J., Preadipocytes of type 2 diabetes subjects display an intrinsic gene expression profile of decreased differentiation capacity. International Journal of Obesity 2011 35 1154 1164
58. Joffe B. I., Goldberg R. B., Feinstein J., Adipose cell size in obese Africans: evidence against the existence of insulin resistance in some patients. Journal of Clinical Pathology 1979 32 5 471 474 2-s2.0-0018763062 (Pubitemid 9207992)
59. McLaughlin T., Sherman A., Tsao P., Gonzalez O., Yee G., Lamendola C., Reaven G. M., Cushman S. W., Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia 2007 50 8 1707 1715 2-s2.0-34447130417 10.1007/s00125-007-0708-y (Pubitemid 47036653)
60. Pasarica M., Rood J., Ravussin E., Schwarz J. M., Smith S. R., Redman L. M., Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis. Journal of Clinical Endocrinology and Metabolism 2010 95 8 4052 4055 2-s2.0-77955404793 10.1210/jc.2009-2377
61. Pasarica M., Sereda O. R., Redman L. M., Albarado D. C., Hymel D. T., Roan L. E., Rood J. C., Burk D. H., Smith S. R., Reduced adipose tissue oxygenation in human obesity evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes 2009 58 3 718 725 2-s2.0-62749167010 10.2337/db08-1098
62. Manalo D. J., Rowan A., Lavoie T., Natarajan L., Kelly B. D., Ye S. Q., Garcia J. G. N., Semenza G. L., Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 2005 105 2 659 669 2-s2.0-11244315697 10.1182/blood-2004-07-2958 (Pubitemid 40070750)
63. Schofield C. J., Ratcliffe P. J., Oxygen sensing by HIF hydroxylases. Nature Reviews Molecular Cell Biology 2004 5 5 343 354 2-s2.0-2342644926 10.1038/nrm1366 (Pubitemid 38579472)
64. Halberg N., Khan T., Trujillo M. E., Hypoxia-inducible factor 1 induces fibrosis and insulin resistance in white adipose tissue. Molecular and Cellular Biology 2009 29 4467 4483
65. Alessi M. C., Bastelica D., Morange P., Berthet B., Leduc I., Verdier M., Geel O., Juhan-Vague I., Plasminogen activator inhibitor 1, transforming growth factor- β 1, and BMI are closely associated in human adipose tissue during morbid obesity. Diabetes 2000 49 8 1374 1380 2-s2.0-0033853610 (Pubitemid 30624239)
66. Festa A., D'Agostino R., Rich S. S., Jenny N. S., Tracy R. P., Haffner S. M., Promoter (4G/5G) plasminogen activator inhibitor-1 genotype and plasminogen activator inhibitor-1 levels in blacks, hispanics, and non-hispanic whites: The Insulin Resistance Atherosclerosis Study. Circulation 2003 107 19 2422 2427 2-s2.0-0038518463 10.1161/01.CIR.0000066908.82782.3A (Pubitemid 36605223)
67. Matsuzawa-Nagata N., Takamura T., Ando H., Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity. Metabolism 2008 57 1071 1077 (Pubitemid 351978066)
68. Fisher G., Alvarez J. A., Ellis A. C., Race differences in the association of oxidative stress with insulin sensitivity in African- and European-American women. Obesity 2009 20 5 972 977
69. Hotamisligil G. S., Molecular mechanisms of insulin resistance and the role of the adipocyte. International Journal of Obesity 2000 24 supplement 4 S23 S27
70. McLaughlin T., Deng A., Gonzales O., Aillaud M., Yee G., Lamendola C., Abbasi F., Connolly A. J., Sherman A., Cushman S. W., Reaven G., Tsao P. S., Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women. Diabetologia 2008 51 12 2303 2308 2-s2.0-55649105421 10.1007/s00125-008-1148-z
71. Madan A. K., Tichansky D. S., Coday M., Fain J. N., Comparison of IL-8, IL-6 and PGE2 formation by visceral (omental) adipose tissue of obese caucasian compared to African-American women. Obesity Surgery 2006 16 10 1342 1350 2-s2.0-33750570443 10.1381/096089206778663652 (Pubitemid 44671808)
72. Evans J., Goedecke J. H., Söderström I., Depot- and ethnic-specific differences in the relationship between adipose tissue inflammation and insulin sensitivity. Clinical Endocrinology 2010 74 51 59
73. Kim C. X., Bailey K. R., Klee G. G., Ellington A. A., Liu G., Mosley T. H., Rehman H., Kullo I. J., Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: The Mayo Clinic proteomic markers of arteriosclerosis study. PLoS ONE 2010 5 2, article e9065 2-s2.0-77949393795 10.1371/journal.pone.0009065
74. Snel M., Jonker J. T., Schoones J., Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions. International Journal of Endocrinology 2012 2012 1 18
75. Hwang J. H., Stein D. T., Barzilai N., Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies. American Journal of Physiology 2007 293 E1663 E1669 (Pubitemid 350255117)
76. Guerrero R., Vega G. L., Grundy S. M., Browning J. D., Ethnic differences in hepatic steatosis: an insulin resistance paradox? Hepatology 2009 49 3 791 801 2-s2.0-63349086412 10.1002/hep.22726
77. Browning J. D., Szczepaniak L. S., Dobbins R., Nuremberg P., Horton J. D., Cohen J. C., Grundy S. M., Hobbs H. H., Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004 40 6 1387 1395 2-s2.0-10644220306 10.1002/hep.20466 (Pubitemid 39657013)
78. Liska D., Dufour S., Zern T. L., Taksali S., Calí A. M. G., Dziura J., Shulman G. I., Pierpont B. M., Caprio S., Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents. PLoS ONE 2007 2 6, article e569 2-s2.0-39349106660 10.1371/journal.pone.0000569 (Pubitemid 351260212)
79. Albu J. B., Kovera A. J., Allen L., Wainwright M., Berk E., Raja-Khan N., Janumala I., Burkey B., Heshka S., Gallagher D., Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women. American Journal of Clinical Nutrition 2005 82 6 1210 1217 2-s2.0-33644697339 (Pubitemid 43779719)
80. Ryan A. S., Nicklas B. J., Berman D. M., Racial differences in insulin resistance and mid-thigh fat deposition in postmenopausal women. Obesity Research 2002 10 5 336 344 2-s2.0-0036582458 (Pubitemid 135688243)
81. Lawrence J. C., Newcomer B. R., Buchthal S. D., Sirikul B., Oster R. A., Hunter G. R., Gower B. A., Relationship of intramyocellular lipid to insulin sensitivity may differ with ethnicity in healthy girls and women. Obesity 2011 19 1 43 48 2-s2.0-78650677233 10.1038/oby.2010.148
82. Berk E. S., Kovera A. J., Boozer C. N., Pi-Sunyer F. X., Albu J. B., Metabolic inflexibility in substrate use is present in African-American but not Caucasian healthy, premenopausal, nondiabetic women. Journal of Clinical Endocrinology and Metabolism 2006 91 10 4099 4106 2-s2.0-33749566735 10.1210/jc.2005-2411 (Pubitemid 44536891)
83. Privette J. D., Hickner R. C., MacDonald K. G., Pories W. J., Barakat H. A., Fatty acid oxidation by skeletal muscle homogenates from morbidly obese black and white American women. Metabolism 2003 52 6 735 738 2-s2.0-0042313689 10.1016/S0026-0495(03)00034-9 (Pubitemid 36896308)
84. Sirikul B., Relationship between insulin sensitivity and in vivo mitochondrial function in skeletal muscle. American Journal of Physiology 2006 291 E724 E728 (Pubitemid 44484913)
85. Tanner C. J., Barakat H. A., Dohm G. L., Muscle fiber type is associated with obesity and weight loss. American Journal of Physiology 2002 282 E1191 E1196 (Pubitemid 34654686)
86. Silveira L. R., Fiamoncini J., Hirabara S. M., Updating the effects of fatty acids on skeletal muscle. Journal of Cellular Physiology 2008 217 1 12