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Volumn 304, Issue 3, 2013, Pages

Reduced ENaC activity and blood pressure in mice with genetic knockout of the insulin receptor in the renal collecting duct

Author keywords

Benzamil; Hypertension; Metabolic syndrome; Principal cell; Sodium

Indexed keywords

AQUAPORIN 2; BENZAMIL; CHLORIDE; CRE RECOMBINASE; EPITHELIAL SODIUM CHANNEL; INSULIN; INSULIN RECEPTOR; POTASSIUM; SODIUM;

EID: 84873319090     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00161.2012     Document Type: Article
Times cited : (35)

References (61)
  • 2
    • 0026518984 scopus 로고
    • Insulin increases sympathetic activity but not blood pressure in borderline hypertensive humans
    • Anderson EA, Balon TW, Hoffman RP, Sinkey CA, Mark AL. Insulin increases sympathetic activity but not blood pressure in borderline hypertensive humans. Hypertension 19: 621-627, 1992.
    • (1992) Hypertension , vol.19 , pp. 621-627
    • Anderson, E.A.1    Balon, T.W.2    Hoffman, R.P.3    Sinkey, C.A.4    Mark, A.L.5
  • 3
    • 0025995364 scopus 로고
    • Hy-perinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
    • Anderson EA, Hoffman RP, Balon TW, Sinkey CA, Mark AL. Hy-perinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87: 2246-2252, 1991.
    • (1991) J Clin Invest , vol.87 , pp. 2246-2252
    • Anderson, E.A.1    Hoffman, R.P.2    Balon, T.W.3    Sinkey, C.A.4    Mark, A.L.5
  • 4
    • 0030847375 scopus 로고    scopus 로고
    • Insulin receptor-related receptor expression in non-A intercalated cells in the kidney
    • Bates CM, Merenmies JM, Kelly-Spratt KS, Parada LF. Insulin receptor-related receptor expression in non-A intercalated cells in the kidney. Kidney Int 52: 674-681, 1997.
    • (1997) Kidney Int , vol.52 , pp. 674-681
    • Bates, C.M.1    Merenmies, J.M.2    Kelly-Spratt, K.S.3    Parada, L.F.4
  • 5
    • 33645332607 scopus 로고    scopus 로고
    • Metabolic risk factors and markers of cardiovascular and renal damage in overweight subjects
    • Bigazzi R, Bianchi S, Batini V, Guzzo D, Campese VM. Metabolic risk factors and markers of cardiovascular and renal damage in overweight subjects. Am J Hypertens 19: 426-431, 2006.
    • (2006) Am J Hypertens , vol.19 , pp. 426-431
    • Bigazzi, R.1    Bianchi, S.2    Batini, V.3    Guzzo, D.4    Campese, V.M.5
  • 6
    • 0037573575 scopus 로고    scopus 로고
    • Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity
    • Blazer-Yost BL, Esterman MA, Vlahos CJ. Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity. Am J Physiol Cell Physiol 284: C1645-C1653, 2003.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Blazer-Yost, B.L.1    Esterman, M.A.2    Vlahos, C.J.3
  • 8
    • 0029018312 scopus 로고
    • Obesity and hypertension: Roles of hyperinsulinemia, sympathetic nervous system and intrarenal mechanisms
    • Brands MW, Hall JE, Van Vliet BN, Alonso-Galicia M, Herrera GA, Zappe D. Obesity and hypertension: roles of hyperinsulinemia, sympathetic nervous system and intrarenal mechanisms. J Nutr 125: 1725S-1731S, 1995.
    • (1995) J Nutr , vol.125
    • Brands, M.W.1    Hall, J.E.2    van Vliet, B.N.3    Alonso-Galicia, M.4    Herrera, G.A.5    Zappe, D.6
  • 11
    • 0032214652 scopus 로고    scopus 로고
    • A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
    • Bruning JC, Michael MD, Winnay JN, Hayashi T, Horsch D, Accili D, Goodyear LJ, Kahn CR. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Mol Cell 2: 559-569, 1998.
    • (1998) Mol Cell , vol.2 , pp. 559-569
    • Bruning, J.C.1    Michael, M.D.2    Winnay, J.N.3    Hayashi, T.4    Horsch, D.5    Accili, D.6    Goodyear, L.J.7    Kahn, C.R.8
  • 12
    • 0344514644 scopus 로고    scopus 로고
    • Insulin receptors and renal sodium handling in hypertensive fructose-fed rats
    • Catena C, Cavarape A, Novello M, Giacchetti G, Sechi LA. Insulin receptors and renal sodium handling in hypertensive fructose-fed rats. Kidney Int 64: 2163-2171, 2003.
    • (2003) Kidney Int , vol.64 , pp. 2163-2171
    • Catena, C.1    Cavarape, A.2    Novello, M.3    Giacchetti, G.4    Sechi, L.A.5
  • 13
    • 0026672856 scopus 로고
    • Insulin-like growth factor system gene expression in the human kidney
    • Chin E, Bondy C. Insulin-like growth factor system gene expression in the human kidney. J Clin Endocrinol Metab 75: 962-968, 1992.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 962-968
    • Chin, E.1    Bondy, C.2
  • 15
    • 0019499535 scopus 로고
    • The effect of insulin on renal sodium metabolism. A review with clinical implications
    • DeFronzo RA. The effect of insulin on renal sodium metabolism. A review with clinical implications. Diabetologia 21: 165-171, 1981.
    • (1981) Diabetologia , vol.21 , pp. 165-171
    • Defronzo, R.A.1
  • 16
    • 0016659653 scopus 로고
    • The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man
    • DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ. The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man. J Clin Invest 55: 845-855, 1975.
    • (1975) J Clin Invest , vol.55 , pp. 845-855
    • Defronzo, R.A.1    Cooke, C.R.2    Andres, R.3    Faloona, G.R.4    Davis, P.J.5
  • 18
    • 84857254245 scopus 로고    scopus 로고
    • A new look at electrolyte transport in the distal tubule
    • Eladari D, Chambrey R, Peti-Peterdi J. A new look at electrolyte transport in the distal tubule. Annu Rev Physiol 74: 325-349, 2012.
    • (2012) Annu Rev Physiol , vol.74 , pp. 325-349
    • Eladari, D.1    Chambrey, R.2    Peti-Peterdi, J.3
  • 22
    • 0025204579 scopus 로고
    • Effect of natriuretic agents, vasoactive agents and of the inhibition of metabolism on sodium handling in the isolated perfused kidney of the nephrotic rat
    • Firth JD, Ledingham JG. Effect of natriuretic agents, vasoactive agents and of the inhibition of metabolism on sodium handling in the isolated perfused kidney of the nephrotic rat. Clin Sci (Lond) 79: 559-574, 1990.
    • (1990) Clin Sci (Lond) , vol.79 , pp. 559-574
    • Firth, J.D.1    Ledingham, J.G.2
  • 23
    • 84861165074 scopus 로고    scopus 로고
    • Effects of insulin on Na and K transporters in the rat CCD
    • Frindt G, Palmer LG. Effects of insulin on Na and K transporters in the rat CCD. Am J Physiol Renal Physiol 302: F1227-F1233, 2012.
    • (2012) Am J Physiol Renal Physiol , vol.302
    • Frindt, G.1    Palmer, L.G.2
  • 24
    • 33846224364 scopus 로고    scopus 로고
    • IGF-1 vs. insulin: Respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line
    • Gonzalez-Rodriguez E, Gaeggeler HP, Rossier BC. IGF-1 vs. insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line. Kidney Int 71: 116-125, 2007.
    • (2007) Kidney Int , vol.71 , pp. 116-125
    • Gonzalez-Rodriguez, E.1    Gaeggeler, H.P.2    Rossier, B.C.3
  • 25
    • 0026513742 scopus 로고
    • Effects of insulin on renal sodium excretion
    • Gupta AK, Clark RV, Kirchner KA. Effects of insulin on renal sodium excretion. Hypertension 19: I78-182, 1992.
    • (1992) Hypertension , vol.19 , pp. 178-182
    • Gupta, A.K.1    Clark, R.V.2    Kirchner, K.A.3
  • 26
    • 0032764089 scopus 로고    scopus 로고
    • Mechanisms of hypertension and kidney disease in obesity
    • Hall JE, Brands MW, Henegar JR. Mechanisms of hypertension and kidney disease in obesity. Ann NY Acad Sci 892: 91-107, 1999.
    • (1999) Ann NY Acad Sci , vol.892 , pp. 91-107
    • Hall, J.E.1    Brands, M.W.2    Henegar, J.R.3
  • 28
    • 0024519129 scopus 로고
    • Does chronic hyperinsulinemia cause hypertension?
    • Hall JE, Coleman TG, Mizelle HL. Does chronic hyperinsulinemia cause hypertension? Am J Hypertens 2: 171-173, 1989.
    • (1989) Am J Hypertens , vol.2 , pp. 171-173
    • Hall, J.E.1    Coleman, T.G.2    Mizelle, H.L.3
  • 29
    • 0032964242 scopus 로고    scopus 로고
    • Exogenous hyperinsulinemia causes insulin resistance, hyperendothelinemia, and subsequent hypertension in rats
    • Juan CC, Fang VS, Kwok CF, Perng JC, Chou YC, Ho LT. Exogenous hyperinsulinemia causes insulin resistance, hyperendothelinemia, and subsequent hypertension in rats. Metabolism 48: 465-471, 1999.
    • (1999) Metabolism , vol.48 , pp. 465-471
    • Juan, C.C.1    Fang, V.S.2    Kwok, C.F.3    Perng, J.C.4    Chou, Y.C.5    Ho, L.T.6
  • 32
    • 0026569449 scopus 로고
    • Hyperinsulinemia: Possible role in obesity-induced hypertension
    • Landsberg L. Hyperinsulinemia: possible role in obesity-induced hypertension. Hypertension 19: I61-I66, 1992.
    • (1992) Hypertension , vol.19
    • Landsberg, L.1
  • 34
    • 0032698749 scopus 로고    scopus 로고
    • Aldo-sterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney
    • Masilamani S, Kim GH, Mitchell C, Wade JB, Knepper MA. Aldo-sterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney. J Clin Invest 104: R19-R23, 1999.
    • (1999) J Clin Invest , vol.104
    • Masilamani, S.1    Kim, G.H.2    Mitchell, C.3    Wade, J.B.4    Knepper, M.A.5
  • 35
    • 0028222280 scopus 로고
    • Chronic insulin administration elevates blood pressure in rats
    • Meehan WP, Buchanan TA, Hsueh W. Chronic insulin administration elevates blood pressure in rats. Hypertension 23: 1012-1017, 1994.
    • (1994) Hypertension , vol.23 , pp. 1012-1017
    • Meehan, W.P.1    Buchanan, T.A.2    Hsueh, W.3
  • 39
    • 0020608862 scopus 로고
    • Insulin binding sites in various segments of the rabbit nephron
    • Nakamura R, Emmanouel DS, Katz AI. Insulin binding sites in various segments of the rabbit nephron. J Clin Invest 72: 388-392, 1983.
    • (1983) J Clin Invest , vol.72 , pp. 388-392
    • Nakamura, R.1    Emmanouel, D.S.2    Katz, A.I.3
  • 41
    • 0035486680 scopus 로고    scopus 로고
    • The role of SGK1 in hormone-regulated sodium transport
    • Pearce D. The role of SGK1 in hormone-regulated sodium transport. Trends Endocrinol Metab 12: 341-347, 2001.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 341-347
    • Pearce, D.1
  • 43
  • 46
    • 0036291255 scopus 로고    scopus 로고
    • Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract
    • Shao X, Somlo S, Igarashi P. Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract. J Am Soc Nephrol 13: 1837-1846, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1837-1846
    • Shao, X.1    Somlo, S.2    Igarashi, P.3
  • 47
    • 0032539923 scopus 로고    scopus 로고
    • In vivo phosphorylation of the epithelial sodium channel
    • Shimkets RA, Lifton R, Canessa CM. In vivo phosphorylation of the epithelial sodium channel. Proc Natl Acad Sci USA 95: 3301-3305, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3301-3305
    • Shimkets, R.A.1    Lifton, R.2    Canessa, C.M.3
  • 48
    • 79961004321 scopus 로고    scopus 로고
    • Signalling by insulin and IGF receptors: Supporting acts and new players
    • Siddle K. Signalling by insulin and IGF receptors: supporting acts and new players. J Mol Endocrinol 47: R1-R10, 2011.
    • (2011) J Mol Endocrinol , vol.47
    • Siddle, K.1
  • 50
    • 33646541375 scopus 로고    scopus 로고
    • Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats
    • Song J, Hu X, Riazi S, Tiwari S, Wade JB, Ecelbarger CA. Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats. Am J Physiol Renal Physiol 290: F1055-F1064, 2006.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Song, J.1    Hu, X.2    Riazi, S.3    Tiwari, S.4    Wade, J.B.5    Ecelbarger, C.A.6
  • 51
    • 8644270550 scopus 로고    scopus 로고
    • Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressure
    • Song J, Hu X, Shi M, Knepper MA, Ecelbarger CA. Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressure. Am J Physiol Renal Physiol 287: F1204-F1212, 2004.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Song, J.1    Hu, X.2    Shi, M.3    Knepper, M.A.4    Ecelbarger, C.A.5
  • 52
    • 34249863860 scopus 로고    scopus 로고
    • Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells
    • Staruschenko A, Pochynyuk O, Vandewalle A, Bugaj V, Stockand JD. Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells. J Am Soc Nephrol 18: 1652-1661, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1652-1661
    • Staruschenko, A.1    Pochynyuk, O.2    Vandewalle, A.3    Bugaj, V.4    Stockand, J.D.5
  • 54
    • 0032925933 scopus 로고    scopus 로고
    • Targeting collecting tubules using the aquaporin-2 promoter
    • Stricklett PK, Nelson RD, Kohan DE. Targeting collecting tubules using the aquaporin-2 promoter. Exp Nephrol 7: 67-74, 1999.
    • (1999) Exp Nephrol , vol.7 , pp. 67-74
    • Stricklett, P.K.1    Nelson, R.D.2    Kohan, D.E.3
  • 55
    • 84873282493 scopus 로고    scopus 로고
    • Increased blood pressure and Na-K-2Cl cotransporter (NKCC2) abundance in response to chronic insulin infusion in mice lacking the insulin receptor in the thick ascending limb through collecting duct (Abstract)
    • Tiwari S, Listhrop R, Ecelbarger CA. Increased blood pressure and Na-K-2Cl cotransporter (NKCC2) abundance in response to chronic insulin infusion in mice lacking the insulin receptor in the thick ascending limb through collecting duct (Abstract). J Am Soc Nephrol 18: 118(A), 2007.
    • (2007) J Am Soc Nephrol , vol.118 , Issue.A , pp. 18
    • Tiwari, S.1    Listhrop, R.2    Ecelbarger, C.A.3
  • 57
    • 44049083146 scopus 로고    scopus 로고
    • Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor
    • Tiwari S, Sharma N, Gill PS, Igarashi P, Kahn CR, Wade JB, Ecelbarger CM. Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor. Proc Natl Acad Sci USA 105: 6469-6474, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6469-6474
    • Tiwari, S.1    Sharma, N.2    Gill, P.S.3    Igarashi, P.4    Kahn, C.R.5    Wade, J.B.6    Ecelbarger, C.M.7
  • 60
    • 0034704119 scopus 로고    scopus 로고
    • Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditions
    • Weisz OA, Wang JM, Edinger RS, Johnson JP. Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditions. J Biol Chem 275: 39886-39893, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 39886-39893
    • Weisz, O.A.1    Wang, J.M.2    Edinger, R.S.3    Johnson, J.P.4
  • 61
    • 10644252734 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells
    • Zhang YH, Alvarez de laRosa D, Canessa CM, Hayslett JP. Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells. Am J Physiol Cell Physiol 288: C141-C147, 2005.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Zhang, Y.H.1    de la Rosa, D.A.2    Canessa, C.M.3    Hayslett, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.