Short hairpin ribonucleic acid constructs targeting insulin-like growth factor binding protein-3 ameliorates diabetes mellitus-related erectile dysfunction in rats

Urology

Volumn 81, Issue 2, 2013, Pages 464.e11-464.e16

  Yang, Zhonghua ^a   Zhou, Zhangyan ^b   Wang, Xinghuan ^a   Peng, Mou ^a   Zhou, Haihong ^a   Meng, Zhe ^a   Chen, Dong ^a   Wang, Yongzhi ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b YANGTZE UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; HYBRID PROTEIN; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 3 SHORT HAIRPIN RIBONUCLEIC ACID FUSION PROTEIN; MESSENGER RNA; SHORT HAIRPIN RNA; SOMATOMEDIN BINDING PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DISEASE ASSOCIATION; DOWN REGULATION; DRUG EFFECT; ELECTROSTIMULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERECTILE DYSFUNCTION; FUSION GENE; GENE CONSTRUCT; GENE EXPRESSION PROFILING; GENE SEQUENCE; GENE TARGETING; GENE TRANSFER; MALE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

EID: 84873285981     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2012.10.045     Document Type: Article

References (20)

1. S. Wild, G. Roglic, and A. Green Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 Diabetes Care 27 2004 1047 1053
2. D. Fedele Therapy Insight: sexual and bladder dysfunction associated with diabetes mellitus Nat Clin Pract Urol 2 2005 282 290 quiz 309
3. C.R. Moore, and R. Wang Pathophysiology and treatment of diabetic erectile dysfunction Asian J Androl 8 2006 675 684
4. A. Castela, R. Soares, and F. Rocha Differentially expressed angiogenic genes in diabetic erectile tissue - results from a microarray screening Mol Genet Metab 105 2012 255 262
5. P. Vorwerk, Y. Oh, and P.D. Lee Synthesis of IGFBP-3 fragments in a baculovirus system and characterization of monoclonal anti-IGFBP-3 antibodies J Clin Endocrinol Metab 82 1997 2368 2370
6. S.M. Firth, and R.C. Baxter Cellular actions of the insulin-like growth factor binding proteins Endocr Rev 23 2002 824 854
7. X.Y. Pu, X.G. Zheng, and Y. Zhang Higher expression of mRNA and protein of insulin-like growth factor binding protein-3 in old rat penile tissues: implications for erectile dysfunction J Sex Med 8 2011 2181 2190
8. X.Y. Pu, X.H. Wang, and W.C. Gao Insulin-like growth factor-1 restores erectile function in aged rats: modulation the integrity of smooth muscle and nitric oxide-cyclic guanosine monophosphate signaling activity J Sex Med 5 2008 1345 1354
9. G.W. Jung, J.Y. Kwak, and S. Yoon IGF-I and TGF-beta2 have a key role on regeneration of nitric oxide synthase (NOS)-containing nerves after cavernous neurotomy in rats Int J Impot Res 11 1999 247 259
10. D. Bochinski, P.S. Hsieh, and L. Nunes Effect of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 complex in cavernous nerve cryoablation Int J Impot Res 16 2004 418 423
11. K. Tan, and R.C. Baxter Serum insulin-like growth factor I levels in adult diabetic patients: the effect of age J Clin Endocrinol Metab 63 1986 651 655
12. K.A. Hwang, Y.J. Hwang, and W. Ha Oral administration of insulin-like growth factor-I from colostral whey reduces blood glucose in streptozotocin-induced diabetic mice Br J Nutr 108 2011 39 45
13. A.A. Butler, V.A. Blakesley, and V. Poulaki Stimulation of tumor growth by recombinant human insulin-like growth factor-I (IGF-I) is dependent on the dose and the level of IGF-I receptor expression Cancer Res 58 1998 3021 3027
14. M.A. Rowlands, J.M. Holly, and D. Gunnell Circulating insulin-like growth factors and IGF-binding proteins in PSA-detected prostate cancer: the large case-control study ProtecT Cancer Res 72 2012 503 515
15. D. LeRoith, and C.T. Roberts Jr. Insulin-like growth factors Ann NY Acad Sci 692 1993 1 9
16. S. Chang, J.A. Hypolite, and M. Velez Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits Am J Physiol Regul Integr Comp Physiol 287 2004 R950 R960
17. C.S. Lin, G. Lin, and T.F. Lue Cyclic nucleotide signaling in cavernous smooth muscle J Sex Med 2 2005 478 491
18. J. Schlossmann, R. Feil, and F. Hofmann Signaling through NO and cGMP-dependent protein kinases Ann Med 35 2003 21 27
19. T.J. Bivalacqua, M.F. Usta, and M. Kendirci Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy J Sex Med 2 2005 187 197 [discussion 197-188]
20. A. Grimberg p53 and IGFBP-3: apoptosis and cancer protection Mol Genet Metab 70 2000 85 98