A rapid HPLC-ESI-MS/MS method for determination of β-asarone, a potential anti-epileptic agent, in plasma after oral administration of Acorus calamus extract to rats

Biomedical Chromatography

Volumn 27, Issue 3, 2013, Pages 318-326

  Nandakumar, Sreenath ^a   Menon, Sasikumar ^b   Shailajan, Sunita ^a  

^a RAMNARAIN RUIA COLLEGE   (India)

^b Sion Koliwada   (India)

Author keywords

Acorus calamus L; HPLC MS MS; Method validation; Pharmacokinetics; asarone

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; EXTRACTION; MASS SPECTROMETERS; MASS SPECTROMETRY; NEURODEGENERATIVE DISEASES; PHASE SEPARATION; RATS;

ACORU CALAMUS L; BIOLOGICAL EFFECTS; COGNITIVE IMPAIRMENT; ELECTROSPRAY IONIZATION SOURCES; HPLC-MS-MS; METHOD VALIDATIONS; ORAL ADMINISTRATION; PHENYLPROPANOIDS; RAT PLASMA; Β-ASARONE;

LIQUID CHROMATOGRAPHY;

ACORUS CALAMUS EXTRACT; BETA ASARONE; CAFFEINE;

AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; FOOD AND DRUG ADMINISTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; QUALITY CONTROL; RAT; SOLID PHASE EXTRACTION; TIME TO MAXIMUM PLASMA CONCENTRATION; WISTAR RAT;

EID: 84873270338     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2794     Document Type: Article

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