Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: Potential markers for periventricular tumors

Neuropathology

Volumn 33, Issue 1, 2013, Pages 17-29

  Szathmari, Alexandru ^a,b   Champier, Jacques ^a   Ghersi Egea, Jean François ^a   Jouvet, Anne ^a   Watrin, Chantal ^a   Wierinckx, Anne ^c   Fèvre Montange, Michelle ^a  

^a UNIVERSITÉ LYON 1   (France)

^b Groupement Hospitalier Est   (France)

^c ProfileXpert   (France)

Author keywords

Circumventricular organs; Claudin 3; Laser capture microdissection; Papillary tumor of the pineal region; Tight junctions

Indexed keywords

CLAUDIN 3; TRANSCRIPTOME; TUMOR MARKER;

AANAT GENE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASMT GENE; BRAIN THIRD VENTRICLE; BRAIN TUMOR; CIRCUMVENTRICULAR ORGAN; CLDN3 GENE; COL11A1 GENE; CONTROLLED STUDY; EPCAM GENE; EPENDYMA; ERBB2 GENE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PINEAL BODY; PRIORITY JOURNAL; RARE DISEASE; RAT; REN1 GENE; SLC22A3 GENE; SUBCOMMISSURAL ORGAN; SUBFORNICAL ORGAN; TIGHT JUNCTION; TPH GENE; UNINDEXED SEQUENCE;

ANIMALS; CEREBRAL VENTRICLE NEOPLASMS; CEREBRAL VENTRICLES; EPENDYMA; LASER CAPTURE MICRODISSECTION; MALE; PINEAL GLAND; RATS; RATS, SPRAGUE-DAWLEY; SUBCOMMISSURAL ORGAN; SUBFORNICAL ORGAN; TRANSCRIPTOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84873245493     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2012.01321.x     Document Type: Article

References (62)

1. Joly JS, Osorio J, Alunni A, Auger H, Kano S, Retaux S. Windows of the brain: towards a developmental biology of circumventricular and other neurohemal organs. Semin Cell Dev Biol 2007; 18: 512-524.
2. Petrov T, Howarth AG, Krukoff TL, Stevenson BR. Distribution of the tight junction-associated protein ZO-1 in circumventricular organs of the CNS. Brain Res Mol Brain Res 1994; 21: 235-246.
3. Rodriguez EM, Rodriguez S, Hein S. The subcommissural organ. Microsc Res Tech 1998; 41: 98-123.
4. Rodríguez EM, Oksche A, Montecinos H. Human subcommissural organ, with particular emphasis on its secretory activity during the fetal life. Microsc Res Tech 2001; 52: 573-590.
5. Jouvet A, Fauchon F, Bouffet E, Saint-Pierre G, Champier J, Fevre-Montange M. Tumors of pineal parenchymal and glial cells. In: Mc Lendon RE, Rosemblum MK, Bigner DD, eds. Russel & Rubinstein's Pathology of Tumors of the Nervous System, 7th edn. London: Chapter 33, Hodder Arnold, 2006; 413-425.
6. Jouvet A, Fauchon F, Liberski P etal. Papillary tumor of the pineal region. Am J Surg Pathol 2003; 27: 505-512.
7. Fevre-Montange M, Champier J, Szathmari A etal. Microarray analysis reveals differential gene expression patterns in tumors of the pineal region. J Neuropathol Exp Neurol 2006; 65: 675-684.
8. Brat DJ, Scheithauer BW, Staugaitis SM, Cortez SC, Brecher K, Burger PC. Third ventricular chordoid glioma: a distinct clinicopathologic entity. J Neuropathol Exp Neurol 1998; 57: 283-290.
9. Pasquier B, Peoc'h M, Morrison AL etal. Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. Am J Surg Pathol 2002; 26: 1330-1342.
10. Wolburg H, Wolburg-Buchholz K, Kraus J etal. Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme. Acta Neuropathol 2003; 105: 586-592.
11. Huang da W, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009; 37: 1-13.
12. Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4: 44-57.
13. Bredel M. Anticancer drug resistance in primary human brain tumors. Brain Res Brain Res Rev 2001; 35: 161-204.
14. Korf HW, Oksche A, Ekstrom P, Gery I, Zigler JS, Klein DC. Pinealocyte projections into the mammalian brain revealed with S-antigen antiserum. Science 1986; 231: 735-737.
15. Jouvet A, Nakazato Y, Scheithauer BW, Paulus W. Papillary tumors of the pineal region. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, eds. WHO Classification of Tumors of the Central Nervous System, 4th edn. Lyon: IARC, 2007; 128-129.
16. Leeds NE, Lang FF, Ribalta T, Sawaya R, Fuller GN. Origin of chordoid glioma of the third ventricle. Arch Pathol Lab Med 2006; 130: 460-464.
17. Bohm C, Newrzella D, Sorgenfrei O. Laser microdissection in CNS research. Drug Discov Today 2005; 10: 1167-1174.
18. Hasselblatt M, Bohm C, Tatenhorst L etal. Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach. Am J Surg Pathol 2006; 30: 66-74.
19. Hasselblatt M, Mertsch S, Koos B etal. TWIST-1 is overexpressed in neoplastic choroid plexus epithelial cells and promotes proliferation and invasion. Cancer Res 2009; 69: 2219-2223.
20. Sotelo-Silveira JR, Calliari A, Kun A, Koenig E, Sotelo JR. RNA trafficking in axons. Traffic 2006; 7: 508-515.
21. Devarajan K, Marchant EG, Rusak B. Circadian and light regulation of oxytocin and parvalbumin protein levels in the ciliated ependymal layer of the third ventricle in the C57 mouse. Neuroscience 2005; 134: 539-547.
22. Hindmarch C, Fry M, Yao ST, Smith PM, Murphy D, Ferguson AV. Microarray analysis of the transcriptome of the subfornical organ in the rat: regulation by fluid and food deprivation. Am J Physiol Regul Integr Comp Physiol 2008; 295: R1914-R1920.
23. Kummer M, Neidert SJ, Johren O, Dominiak P. Orexin (hypocretin) gene expression in rat ependymal cells. Neuroreport 2001; 12: 2117-2120.
24. Carretero J, Burks D, Rubio M etal. Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat. Folia Morphol (Warsz) 2002; 61: 209-216.
25. McKinley MJ, Mathai ML, McAllen RM etal. Vasopressin secretion: osmotic and hormonal regulation by the lamina terminalis. J Neuroendocrinol 2004; 16: 340-347.
26. Davy BE, Robinson ML. Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel gene. Hum Mol Genet 2003; 12: 1163-1170.
27. Dawe HR, Shaw MK, Farr H, Gull K. The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules. BMC Biol 2007; 5: 33.
28. Lechtreck KF, Delmotte P, Robinson ML, Sanderson MJ, Witman GB. Mutations in Hydin impair ciliary motility in mice. J Cell Biol 2008; 180: 633-643.
29. Gilbertson RJ, Bentley L, Hernan R etal. ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease. Clin Cancer Res 2002; 8: 3054-3064.
30. Purow B, Schiff D. Advances in the genetics of glioblastoma: are we reaching critical mass? Nat Rev Neurol 2009; 5: 419-426.
31. Fischer H, Stenling R, Rubio C, Lindblom A. Colorectal carcinogenesis is associated with stromal expression of COL11A1 and COL5A2. Carcinogenesis 2001; 22: 875-878.
32. An JH, Lee SY, Jeon JY, Cho KG, Kim SU, Lee MA. Identification of gliotropic factors that induce human stem cell migration to malignant tumor. J Proteome Res 2009; 8: 2873-2881.
33. Vialou V, Amphoux A, Zwart R, Giros B, Gautron S. Organic cation transporter 3 (Slc22a3) is implicated in salt-intake regulation. J Neurosci 2004; 24: 2846-2851.
34. Sinnayah P, Lazartigues E, Sakai K, Sharma RV, Sigmund CD, Davisson RL. Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response. Circ Res 2006; 99: 1125-1131.
35. Klein DC, Bailey MJ, Carter DA etal. Pineal function: impact of microarray analysis. Mol Cell Endocrinol 2010; 314: 170-183.
36. Sim FJ, Keyoung HM, Goldman JE etal. Neurocytoma is a tumor of adult neuronal progenitor cells. J Neurosci 2006; 26: 12544-12555.
37. Ben-Jonathan N, LaPensee CR, LaPensee EW. What can we learn from rodents about prolactin in humans? Endocr Rev 2008; 29: 1-41.
38. Denison SR, Callahan G, Becker NA, Phillips LA, Smith DI. Characterization of FRA6E and its potential role in autosomal recessive juvenile parkinsonism and ovarian cancer. Genes Chromosomes Cancer 2003; 38: 40-52.
39. Yokoo S, Masuda S, Yonezawa A, Terada T, Katsura T, Inui K. Significance of organic cation transporter 3 (SLC22A3) expression for the cytotoxic effect of oxaliplatin in colorectal cancer. Drug Metab Dispos 2008; 36: 2299-2306.
40. Waters KM, Le Marchand L, Kolonel LN etal. Generalizability of associations from prostate cancer genome-wide association studies in multiple populations. Cancer Epidemiol Biomarkers Prev 2009; 18: 1285-1289.
41. Shnitsar V, Eckardt R, Gupta S etal. Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. Cancer Res 2009; 69: 1494-1501.
42. Malek ZS, Dardente H, Pevet P, Raison S. Tissue-specific expression of tryptophan hydroxylase mRNAs in the rat midbrain: anatomical evidence and daily profiles. Eur J Neurosci 2005; 22: 895-901.
43. Zilberman-Peled B, Appelbaum L, Vallone D etal. Transcriptional regulation of arylalkylamine-N-acetyltransferase-2 gene in the pineal gland of the gilthead seabream. J Neuroendocrinol 2007; 19: 46-53.
44. Rath MF, Bailey MJ, Kim JS etal. Developmental and diurnal dynamics of Pax4 expression in the mammalian pineal gland: nocturnal down-regulation is mediated by adrenergic-cyclic adenosine 3′, 5′-monophosphate signaling. Endocrinology 2009; 150: 803-811.
45. Munoz EM, Bailey MJ, Rath MF etal. NeuroD1: developmental expression and regulated genes in the rodent pineal gland. J Neurochem 2007; 102: 887-899.
46. Fukuda T, Akiyama N, Ikegami M etal. Expression of hydroxyindole-O-methyltransferase enzyme in the human central nervous system and in pineal parenchymal cell tumors. J Neuropathol Exp Neurol 2010; 69: 498-510.
47. Estivill-Torrus G, Vitalis T, Fernandez-Llebrez P, Price DJ. The transcription factor Pax6 is required for development of the diencephalic dorsal midline secretory radial glia that form the subcommissural organ. Mech Dev 2001; 109: 215-224.
48. Gold SJ, Ni YG, Dohlman HG, Nestler EJ. Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. J Neurosci 1997; 17: 8024-8037.
49. Lee SM, Chen L, Chow BK, Yung WH. Endogenous release and multiple actions of secretin in the rat cerebellum. Neuroscience 2005; 134: 377-386.
50. Sarabi A, Hoffer BJ, Olson L, Morales M. Glial cell line neurotrophic factor-family receptor alpha-1 is present in central neurons with distinct phenotypes. Neuroscience 2003; 116: 261-273.
51. Belluardo N, Wu G, Mudo G, Hansson AC, Pettersson R, Fuxe K. Comparative localization of fibroblast growth factor receptor-1, -2, and -3 mRNAs in the rat brain: in situ hybridization analysis. J Comp Neurol 1997; 379: 226-246.
52. Chu JY, Yung WH, Chow BK. Endogenous release of secretin from the hypothalamus. Ann N Y Acad Sci 2006; 1070: 196-200.
53. Huynh H, Ng CY, Lim KB etal. Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary. Endocrinology 2001; 142: 2985-2995.
54. Balzar M, Prins FA, Bakker HA, Fleuren GJ, Warnaar SO, Litvinov SV. The structural analysis of adhesions mediated by Ep-CAM. Exp Cell Res 1999; 246: 108-121.
55. Tsukita S, Furuse M. Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol 2000; 149: 13-16.
56. Hewitt KJ, Agarwal R, Morin PJ. The claudin gene family: expression in normal and neoplastic tissues. BMC Cancer 2006; 6: 186.
57. Kominsky SL, Tyler B, Sosnowski J etal. Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis. Cancer Res 2007; 67: 7977-7982.
58. Mullier A, Bouret SG, Prevot V, Dehouck B. Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain. J Comp Neurol 2010; 518: 943-962.
59. Milatz S, Krug SM, Rosenthal R etal. Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes. Biochim Biophys Acta 2010; 1798: 2048-2057.
60. Leong CT, Ng CY, Ong CK etal. Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44. Oncogene 2004; 23: 5707-5718.
61. Osta WA, Chen Y, Mikhitarian K etal. EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy. Cancer Res 2004; 64: 5818-5824.
62. Munz M, Kieu C, Mack B, Schmitt B, Zeidler R, Gires O. The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation. Oncogene 2004; 23: 5748-5758.