Doxorubicin-conjugated dendrimer/collagen hybrid gels for metastasis-associated drug delivery systems

Acta Biomaterialia

Volumn 9, Issue 3, 2013, Pages 5673-5680

  Kojima, Chie ^a   Suehiro, Tomoyuki ^a   Watanabe, Kenji ^a   Ogawa, Mikako ^b   Fukuhara, Ayano ^a   Nishisaka, Eiko ^a   Harada, Atsushi ^a   Kono, Kenji ^a   Inui, Takashi ^a   Magata, Yasuhiro ^b  

^a Osaka Prefecture University   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Collagen; Dendrimer; Drug delivery; Hydrogel; Metastasis

Indexed keywords

CELLS; CHEMOTHERAPY; COLLAGEN; CONTROLLED DRUG DELIVERY; CYTOLOGY; DISEASES; ENZYME ACTIVITY; ENZYME INHIBITION; PATHOLOGY; TARGETED DRUG DELIVERY;

CELL-BE; CELL/B.E; CELL/BE; COLLAGEN GELS; DOXORUBICIN; DRUG-DELIVERY SYSTEMS; HYBRID GELS; MATRIX; MDA-MB-231; PRODRUGS;

DENDRIMERS;

COLLAGEN; DENDRIMER; DOXORUBICIN; MATRIX METALLOPROTEINASE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; GEL; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL;

EID: 84873192039     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.11.013     Document Type: Article

References (40)

1. C. Kojima Design of stimuli-responsive dendrimers Expert Opin Drug Deliv 7 2010 307 319
2. C. de las Heras Alarcón, S. Pennadam, and C. Alexander Stimuli responsive polymers for biomedical applications Chem Soc Rev 34 2005 276 285 (Pubitemid 40444408)
3. J. Kost, and R. Langer Responsive polymeric delivery systems Adv Drug Deliv Rev 46 2001 125 148 (Pubitemid 33653418)
4. M. Bikram, and J.L. West Thermo-responsive systems for controlled drug delivery Expert Opin Drug Deliv 5 2008 1077 1091
5. D. Schmaljohann Thermo- and pH-responsive polymers in drug delivery Adv Drug Deliv Rev 58 2006 1655 1670 (Pubitemid 44830149)
6. R. Haag, and F. Kratz Polymer therapeutics: concepts and applications Angew Chem Int Ed 45 2006 1198 1215 (Pubitemid 44097641)
7. R. Duncan Polymer conjugates as anticancer nanomedicines Nat Rev Cancer 6 2006 688 701 (Pubitemid 44286001)
8. A. Schroeder, D.A. Heller, M.M. Winslow, J.E. Dahlman, G.W. Pratt, and R. Langer Treating metastatic cancer with nanotechnology Nat Rev Cancer 12 2011 39 50
9. O. Veiseh, F.M. Kievit, R.G. Ellenbogen, and M. Zhang Cancer cell invasion: treatment and monitoring opportunities in nanomedicine Adv Drug Deliv Rev 63 2011 582 596
10. L.M. Coussens, B. Fingleton, and L.M. Matrisian Matrix metalloproteinase inhibitors and cancer: trials and tribulations Science 295 2002 2387 2392 (Pubitemid 34270240)
11. E.A. McSherry, S. Donatello, A.M. Hopkins, and S. McDonnell Molecular basis of invasion in breast cancer Cell Mol Life Sci 64 2007 3201 3218
12. M. Björklund, and E. Koivunen Gelatinase-mediated migration and invasion of cancer cells Biochem Biophys Acta 1755 2005 37 69 (Pubitemid 40720240)
13. A.M. Mansour, J. Drevs, N. Esser, F.M. Hamada, O.A. Badary, and C. Unger A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2 Cancer Res 63 2003 4062 4066 (Pubitemid 36917928)
14. N.R. Sarkar, T. Rosendahl, A.B. Krueger, A.L. Banerjee, K. Benton, and S. Mallik "Uncorking" of liposomes by matrix metalloproteinase-9 Chem Commun 2005 2005 999 1001
15. J.R. Tauro, and R.A. Gemeinhart Matrix metalloprotease triggered delivery of cancer chemotherapeutics from hydrogel matrixes Bioconjug Chem 16 2005 1133 1139 (Pubitemid 41368115)
16. T. Terada, M. Iwai, S. Kawakami, F. Yamashita, and M. Hashida Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting J Control Release 111 2006 333 342
17. H. Hatakeyama, H. Akita, E. Ishida, K. Hashimoto, H. Kobayashi, and T. Aoki Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes Int J Pharm 342 2007 194 200 (Pubitemid 47259319)
18. L.M. Kaminskas, B.D. Kelly, V.M. McLeod, G. Sberna, B.J. Boyd, and D.J. Owen Capping methotrexate α-carboxyl groups enhances systemic exposure and retains the cytotoxicity of drug conjugated PEGylated polylysine dendrimers Mol Pharm 8 2011 338 349
19. K. Gelse, E. Poschl, and T. Aigner Collagens-structure, function, and biosynthesis Adv Drug Deliv Rev 55 2003 1531 1546
20. W. Friess Collagen-biomaterial for drug delivery Eur J Pharm Biopharm 45 1998 113 136
21. D.G. Wallace, and J. Rosenblatt Collagen gel systems for sustained delivery and tissue engineering Adv Drug Deliv Rev 55 2003 1631 1649 (Pubitemid 37412596)
22. S. Svenson, and D.A. Tomalia Dendrimers in biomedical applications-reflections on the field Adv Drug Deliv Rev 57 2005 2106 2129
23. D. Astruc, E. Boisselier, and C. Ornelas Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics, and nanomedicine Chem Rev 110 2010 1857 1959
24. L. Crespo, G. Sanclimens, M. Pons, E. Giralt, M. Royo, and F. Albericio Peptide and amide bond-containing dendrimers Chem Rev 105 2005 1663 1681 (Pubitemid 40773665)
25. K. Kono, C. Kojima, N. Hayashi, E. Nishisaka, K. Kiura, and S. Watarai Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin Biomaterials 29 2008 1664 1675
26. C. Kojima, K. Kono, K. Maruyama, and T. Takagishi Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs Bioconjug Chem 11 2000 910 917
27. C. Kojima, S. Tsumura, A. Harada, and K. Kono A collagen-mimic dendrimer capable of controlled release J Am Chem Soc 131 2009 6052 6053
28. 10-modified dendrimer Biopolymers 95 2011 270 277
29. C. Kojima, T. Suehiro, T. Tada, Y. Sakamoto, T. Waku, and N. Tanaka Preparation of heat-induced artificial collagen gels based on collagen-mimetic dendrimers Soft Matter 7 2011 8991 8997
30. M. Matsusaki, R. Amekawa, M. Matsumoto, Y. Tanaka, A. Kubota, and K. Nishida Physical and specific crosslinking of collagen fibers by supramolecular nanogelators Adv Mater 23 2011 2957 2961
31. S. Hashimoto, Y. Onodera, A. Hashimoto, M. Tanaka, M. Hamaguchi, and A. Yamada Requirement for Arf6 in breast cancer invasive activities Proc Natl Acad Sci 101 2004 6647 6652 (Pubitemid 38586028)
32. T. Hiraga, A. Ueda, D. Tamura, K. Hata, F. Ikeda, and P.J. Williams Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer Int J Cancer 106 2003 973 979 (Pubitemid 37071680)
33. K. Kono, T. Ozawa, T. Yoshida, F. Ozaki, Y. Ishizaka, and K. Maruyama Highly temperature-sensitive liposomes based on a thermosensitive block copolymer for tumor-specific chemotherapy Biomaterials 31 2010 7096 7105
34. D. Grobelny, L. Poncz, and R.E. Galardy Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids Biochemistry 31 1992 7152 7154
35. J.E. Bartsch, E.D. Staren, and H.E. Appert Matrix metalloproteinase expression in breast cancer J Surg Res 110 2003 383 392 (Pubitemid 36683036)
36. A. Ahmad, D. Kong, Z. Wang, S.H. Sarkar, S. Banerjee, and F.H. Sarkar Down-regulation of uPA and uPAR by 3,3′-diindolylmethane contributes to the inhibition of cell growth and migration of breast cancer cells J Cell Biochem 108 2009 916 925
37. S.-K. Shon, A. Kim, J.Y. Kim, K.I. Kim, Y. Yang, and J.-S. Lim Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells Biochem Biophys Res Commun 385 2009 198 203
38. R.A. Cardone, V. Casavola, and S.J. Reshkin The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis Nat Rev Cancer 5 2005 786 795 (Pubitemid 41400778)
39. L.M. Kaminskas, V.M. McLeod, B.D. Kelly, C. Cullinane, G. Sberna, and M. Williamson Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor models Mol Pharm 9 2012 422 432
40. Kojima C, Nishisaka E, Suehiro T, Watanabe K, Harada A, Goto T, et al., submitted for publication.