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Volumn 42, Issue 8, 2012, Pages 719-730
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Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes.
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Author keywords
[No Author keywords available]
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Indexed keywords
CYTOCHROME P450;
DRUG DERIVATIVE;
ENZYME INHIBITOR;
FURAFYLLINE;
ISOENZYME;
MESSENGER RNA;
THEOPHYLLINE;
ANIMAL;
ARTICLE;
DRUG ANTAGONISM;
DRUG DETOXIFICATION;
DRUG EFFECT;
ENZYME SPECIFICITY;
ENZYMOLOGY;
GENE EXPRESSION REGULATION;
GENETICS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
IC 50;
INTESTINE;
KINETICS;
LIVER;
LIVER MICROSOME;
MACACA FASCICULARIS;
MALE;
MASS SPECTROMETRY;
METABOLISM;
OXIDATION REDUCTION REACTION;
STANDARD;
TIME;
ANIMALS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CYTOCHROME P-450 ENZYME SYSTEM;
ENZYME INHIBITORS;
GENE EXPRESSION REGULATION, ENZYMOLOGIC;
HUMANS;
INHIBITORY CONCENTRATION 50;
INTESTINES;
ISOENZYMES;
KINETICS;
LIVER;
MACACA FASCICULARIS;
MALE;
MASS SPECTROMETRY;
METABOLIC DETOXICATION, DRUG;
MICROSOMES, LIVER;
OXIDATION-REDUCTION;
REFERENCE STANDARDS;
RNA, MESSENGER;
SUBSTRATE SPECIFICITY;
THEOPHYLLINE;
TIME FACTORS;
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EID: 84873176765
PISSN: None
EISSN: 13665928
Source Type: Journal
DOI: 10.3109/00498254.2012.656732 Document Type: Article |
Times cited : (10)
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References (0)
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