Isolation, characterization, and bioactivity evaluation of 3-((6-methylpyrazin-2-yl)methyl)-1H-indole, a new alkaloid from a deep-sea-derived actinomycete serinicoccus profundi sp. nov.

Marine Drugs

Volumn 11, Issue 1, 2013, Pages 33-39

  Yang, Xian Wen ^a,b   Zhang, Gai Yun ^c   Ying, Jian Xi ^c   Yang, Bing ^b   Zhou, Xue Feng ^b   Steinmetz, Andre ^a   Liu, Yong Hong ^b   Wang, Ning ^a  

^a LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^b SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^c Key Laboratory of Marine Genetic Resources of Fujian Province   (China)

Author keywords

Actinomycete; Alkaloid; Antibacterial activity; Cytotoxicity; Deep sea sediment; Serinicoccus profundi sp. nov.

Indexed keywords

3 [(6 METHYLPYRAZIN 2 YL)METHYL] 1H INDOLE; 4 (2 HYDROXYPHENYL) 4 OXOBUTANOIC ACID; ALKALOID; ANTIBIOTIC AGENT; CYCLO(PROLYLPHENYLALANINE); CYCLO(PROLYLTYROSINE); CYTOTOXIC AGENT; N (4 HYDROXYPHENETHYL)ACETAMIDE; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACILLUS THURINGIENSIS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SERINICOCCUS PROFUNDI; STAPHYLOCOCCUS AUREUS; TUMOR CELL CULTURE;

EID: 84873174000     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md11010033     Document Type: Article

References (17)

1. Goodfellow, M.; Stach, J.E.; Brown, R.; Bonda, A.N.; Jones, A.L.; Mexson, J.; Fiedler, H.P.; Zucchi, T.D.; Bull, A.T. Verrucosispora maris sp. nov., a novel deep-sea actinomycete isolated from a marine sediment which produces abyssomicins. Antonie Van Leeuwenhoek 2012, 101, 185-193.
2. Tian, X.P.; Xu, Y.; Zhang, J.; Li, J.; Chen, Z.; Kim, C.J.; Li, W.J.; Zhang, C.S.; Zhang, S. Streptomyces oceani sp. nov., a new obligate marine actinomycete isolated from a deep-sea sample of seep authigenic carbonate nodule in South China Sea. Antonie Van Leeuwenhoek 2012, 102, 335-343.
3. Luo, Y.; Xiao, J.; Wang, Y.; Xu, J.; Xie, S.; Xu, J. Streptomyces indicus sp. nov., an actinomycete isolated from deep-sea sediment. Int. J. Syst. Evol. Microbiol. 2011, 61, 2712-2716.
4. Li, J.; Zhao, G.Z.; Long, L.J.; Wang, F.Z.; Tian, X.P.; Zhang, S.; Li, W.J. Rhodococcus nanhaiensis sp. nov., an actinobacterium isolated from marine sediment. Int. J. Syst. Evol. Microbiol. 2012, 62, 2517-2521.
5. Zhang, W.; Liu, Z.; Li, S.; Yang, T.; Zhang, Q.; Ma, L.; Tian, X.; Zhang, H.; Huang, C.; Zhang, S.; et al. Spiroindimicins A-D: New bisindole alkaloids from a deep-sea-derived actinomycete. Org. Lett. 2012, 14, 3364-3367.
6. Huang, H.; Yang, T.; Ren, X.; Liu, J.; Song, Y.; Sun, A.; Ma, J.; Wang, B.; Zhang, Y.; Huang, C.; et al. Cytotoxic angucycline class glycosides from the deep sea actinomycete Streptomyces lusitanus SCSIO LR32. J. Nat. Prod. 2012, 75, 202-208.
7. Li, S.; Tian, X.; Niu, S.; Zhang, W.; Chen, Y.; Zhang, H.; Yang, X.; Zhang, W.; Li, W.; Zhang, S.; et al. Pseudonocardians A-C, new diazaanthraquinone derivatives from a deap-sea actinomycete Pseudonocardia sp. SCSIO 01299. Mar. Drugs 2011, 9, 1428-1439.
8. Abdel-Mageed, W.M.; Milne, B.F.; Wagner, M.; Schumacher, M.; Sandor, P.; Pathom-aree, W.; Goodfellow, M.; Bull, A.T.; Horikoshi, K.; Ebel, R.; et al. Dermacozines, a new phenazine family from deep-sea dermacocci isolated from a Mariana Trench sediment. Org. Biomol. Chem. 2010, 8, 2352-2362.
9. Sato, S.; Iwata, F.; Yamada, S.; Kawahara, H.; Katayama, M. Usabamycins A-C: New anthramycin-type analogues from a marine-derived actinomycete. Bioorg. Med. Chem. Lett. 2011, 21, 7099-7101.
10. Yi, H.; Schumann, P.; Sohn, K.; Chun, J. Serinicoccus marinus gen. nov., sp. nov., a novel actinomycete with L-ornithine and L-serine in the peptidoglycan. Int. J. Syst. Evol. Microbiol. 2004, 54, 1585-1859.
11. Traiwan, J.; Park, M.H.; Kim, W. Serinicoccus chungangensis sp. nov., isolated from tidal flat sediment, and emended description of the genus Serinicoccus. Int. J. Syst. Evol. Microbiol. 2011, 61, 1299-1303.
12. Xiao, J.; Luo, Y.; Xie, S.; Xu, J. Serinicoccus profundi sp. nov., an actinomycete isolated from deep-sea sediment, and emended description of the genus Serinicoccus. Int. J. Syst. Evol. Microbiol. 2011, 61, 16-19.
13. Li, Y.Q.; Huang, X.S.; Li, M.G.; Sattler, I.; Wen, M.L.; Grabley, S. A new compound isolated from a bioactive streptomycete. Chin. Chem. Lett. 2005, 16, 613-615.
14. Adamczeski, M.; Reed, A.R.; Crews, P. New and known diketopiperazines from the Caribbean sponge, Calyx cf. podatypa. J. Nat. Prod. 1995, 58, 201-208.
15. Jayatilake, G.S.; Thornton, M.P.; Leonard, A.C.; Grimwade, J.E.; Baker, B.J. Metabolites from an Antarctic sponge-associated bacterium, Pseudomonas aeruginosa. J. Nat. Prod. 1996, 59, 293-296.
16. Yang, X.W.; Zeng, H.W.; Liu, X.H.; Li, S.M.; Xu, W.; Shen, Y.H.; Zhang, C.; Zhang, W.D. Anti-inflammatory and anti-tumour effects of Abies georgei extracts. J. Pharm. Pharmacol. 2008, 60, 937-941.
17. Xiao, Y.; Li, S.; Niu, S.; Ma, L.; Zhang, G.; Zhang, H.; Zhang, G.; Ju, J.; Zhang, C. Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase. J. Am. Chem. Soc. 2011, 133, 1092-1105.