MicroRNA-15a promotes neuroblastoma migration by targeting reversion-inducing cysteine-rich protein with Kazal motifs (RECK) and regulating matrix metalloproteinase-9 expression

FEBS Journal

Volumn 280, Issue 3, 2013, Pages 855-866

  Xin, Chen ^a   Buhe, Bao ^b   Hongting, Lu ^a   Chuanmin, Yang ^a   Xiwei, Hao ^a   Hong, Zhang ^a   Lulu, Han ^a   Qian, Dong ^a   Renjie, Wang ^b  

^a QINGDAO UNIVERSITY   (China)

^b Pingjin Hospital   (China)

Author keywords

matrix metalloproteinase 9 (MMP 9); microRNA 15a; migration; neuroblastoma; reversion inducing cysteine rich protein with Kazal motifs (RECK)

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; GELATINASE B; MEMBRANE PROTEIN; MICRORNA 15A; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CANCER CELL; CANCER INVASION; CANCER STAGING; CELL MIGRATION; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; MIGRATION INHIBITION; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF GENE;

3' UNTRANSLATED REGIONS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION REGULATION, NEOPLASTIC; GPI-LINKED PROTEINS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MATRIX METALLOPROTEINASE 9; MICRORNAS; MODELS, GENETIC; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM STAGING; NEUROBLASTOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SPECTROMETRY, FLUORESCENCE;

EID: 84873159880     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12074     Document Type: Article

References (41)

1. Maris JM, (2010) Recent advances in neuroblastoma. N Engl J Med 362, 2202-2211.
2. Steeg PS, (2006) Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 12, 895-904.
3. Nevo I, et al,. (2010) Gene-expression-based analysis of local and metastatic neuroblastoma variants reveals a set of genes associated with tumor progression in neuroblastoma patients. Int J Cancer 126, 1570-1581.
4. Takahashi C, et al,. (1998) Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK. Proc Natl Acad Sci USA 95, 13221-13226.
5. Oh J, et al,. (2001) The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell 107, 789-800.
6. Furumoto K, et al,. (2001) RECK gene expression in hepatocellular carcinoma: correlation with invasion-related clinicopathological factors and its clinical significance. Reverse-inducing-cysteine-rich protein with Kazal motifs. Hepatology 33, 189-195.
7. Takeuchi T, et al,. (2004) The membrane-anchored matrix metalloproteinase (MMP) regulator RECK in combination with MMP-9 serves as an informative prognostic indicator for colorectal cancer. Clin Cancer Res 10, 5572-5579.
8. Noda M, &, Takahashi C, (2007) Recklessness as a hallmark of aggressive cancer. Cancer Sci 98, 1659-1665.
9. Simizu S, Takagi S, Tamura Y, &, Osada H, (2005) RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines. Cancer Res 65, 7455-7461.
10. Chang CK, Hung WC, &, Chang HC, (2008) The Kazal motifs of RECK protein inhibit MMP-9 secretion and activity and reduce metastasis of lung cancer cells in vitro and in vivo. J Cell Mol Med 12, 2781-2789.
11. Dong Q, Yu D, Yang CM, Jiang B, &, Zhang H, (2010) Expression of the reversion-inducing cysteine-rich protein with Kazal motifs and matrix metalloproteinase-14 in neuroblastoma and the role in tumour metastasis. Int J Exp Pathol 91, 368-373.
12. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297.
13. Lim LP, et al,. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773.
14. Pillai RS, Bhattacharyya SN, &, Filipowicz W, (2007) Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol 17, 118-126.
15. Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS, &, Krichevsky AM, (2008) MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 28, 5369-5380.
16. Guo J, et al,. (2010) Identification of miRNAs that are associated with tumor metastasis in neuroblastoma. Cancer Biol Ther 9, 446-452.
17. Chen PS, et al,. (2011) miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans. J Clin Invest 121, 3442-3455.
18. Takagi S, Simizu S, &, Osada H, (2009) RECK negatively regulates matrix metalloproteinase-9 transcription. Cancer Res 69, 1502-1508.
19. Chen Y, &, Stallings RL, (2007) Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis. Cancer Res 67, 976-983.
20. Calin GA, et al,. (2005) A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353, 1793-1801.
21. Cimmino A, et al,. (2005) miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102, 13944-13949.
22. Calin GA, et al,. (2008) MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci USA 105, 5166-5171.
23. Bonci D, et al,. (2008) The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 14, 1271-1277.
24. Bottoni A, Piccin D, Tagliati F, Luchin A, Zatelli MC, &, degli Uberti EC, (2005) miR-15a and miR-16-1 down-regulation in pituitary adenomas. J Cell Physiol 204, 280-285.
25. Bandi N, et al,. (2009) miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. Cancer Res 69, 5553-5559.
26. Zhang XJ, Ye H, Zeng CW, He B, Zhang H, &, Chen YQ, (2010) Dysregulation of miR-15a and miR-214 in human pancreatic cancer. J Hematol Oncol 3, 46-54.
27. Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C, &, Zheng ZM, (2008) Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One 3, e2557.
28. Keklikoglou I, et al,. (2011) MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kappaB and TGF-beta signaling pathways. Oncogene 31, 4150-4163.
29. Wu N, Liu X, Xu X, Fan X, Liu M, Li X, Zhong Q, &, Tang H, (2011) MicroRNA-373, a new regulator of protein phosphatase 6, functions as an oncogene in hepatocellular carcinoma. FEBS J 278, 2044-2054.
30. Ma L, et al,. (2010) miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 12, 247-256.
31. Guo LM, Pu Y, Han Z, Liu T, Li YX, Liu M, Li X, &, Tang H, (2009) MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1. FEBS J 276, 5537-5546.
32. Wan HY, Guo LM, Liu T, Liu M, Li X, &, Tang H, (2010) Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma. Mol Cancer 9, 16-27.
33. Peng RQ, Wan HY, Li HF, Liu M, Li X, &, Tang H, (2012) MicroRNA-214 suppresses the growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-alpha- d -galactosamine:polypeptide N- acetylgalactosaminyltransferase 7. J Biol Chem 287, 14301-14309.
34. Qiang R, et al,. (2011) Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells. Int J Biochem Cell Biol 43, 632-641.
35. Zhang B, Zhang J, Xu ZY, &, Xie HL, (2009) Expression of RECK and matrix metalloproteinase-2 in ameloblastoma. BMC Cancer 9, 427.
36. Masui T, et al,. (2003) RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis. Clin Cancer Res 9, 1779-1784.
37. Chang HC, Cho CY, &, Hung WC, (2006) Silencing of the metastasis suppressor RECK by RAS oncogene is mediated by DNA methyltransferase 3b-induced promoter methylation. Cancer Res 66, 8413-8420.
38. Oh J, Diaz T, Wei B, Chang H, Noda M, &, Stetler-Stevenson WG, (2006) TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118. Oncogene 25, 4230-4234.
39. Oh J, et al,. (2004) Tissue inhibitor of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK. Cancer Res 64, 9062-9069.
40. Miki T, Shamma A, Kitajima S, Takegami Y, Noda M, Nakashima Y, Watanabe K, &, Takahashi C, (2010) The ss1-integrin-dependent function of RECK in physiologic and tumor angiogenesis. Mol Cancer Res 8, 665-676.
41. Chen C, et al,. (2005) Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 33, e179.