Many randomized trials of physical therapy interventions are not adequately registered: A survey of 200 published trials

Physical Therapy

Volumn 93, Issue 3, 2013, Pages 299-309

  Pinto, Rafael Zambelli ^a   Elkins, Mark R ^b,c   Moseley, Anne M ^c   Sherrington, Catherine ^c   Herbert, Robert D ^d   Maher, Christopher G ^e   Ferreira, Paulo H ^c   Ferreira, Manuela L ^c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIBLIOMETRICS; HUMAN; PHYSIOTHERAPY; PUBLICATION; PUBLISHING; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGISTER; RETROSPECTIVE STUDY; STATISTICS;

BIBLIOMETRICS; HUMANS; PERIODICALS AS TOPIC; PHYSICAL THERAPY MODALITIES; PUBLISHING; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REGISTRIES; RETROSPECTIVE STUDIES;

MLCS; MLOWN;

EID: 84873138810     PISSN: 00319023     EISSN: 15386724     Source Type: Journal    
DOI: 10.2522/ptj.20120206     Document Type: Article

References (39)

1. Dickersin K, Chan S, Chalmers TC, et al. Publication bias and clinical trials. Control Clin Trials. 1987;8:343-353
2. Hopewell S, Loudon K, Clarke MJ, et al. Publication bias in clinical trials due to statistical significance or direction of trial results. Cochrane Database Syst Rev. 2009;(1):MR000006
3. Chalmers I. Misconduct in medical research. BMJ. 1989;298:256
4. Hahn S, Williamson PR, Hutton JL. Investigation of within-study selective reporting in clinical research: follow-up of applications submitted to a local research ethics committee. J Eval Clin Pract. 2002;8: 353-359
5. Hahn S, Williamson PR, Hutton JL, et al. Assessing the potential for bias in metaanalysis due to selective reporting of subgroup analyses within studies. Stat Med. 2000;19:3325-3336
6. Chalmers I. Underreporting research is scientific misconduct. JAMA. 1990;263: 1405-1408
7. Dickersin K. The existence of publication bias and risk factors for its occurrence. JAMA. 1990;263:1385-1389
8. World Health Organization. International clinical trials registry platform. Available at: http://www.who.int/ictrp/trial_reg/en/ index.html. Accessed November 16, 2009
9. World Health Organization. WHO trial registration data set (version 1.2.1). Available at: http://www.who.int/ictrp/network/ trds/en/index.html. Accessed July 9, 2012
10. Moher D. Clinical-trial registration: a call for its implementation in Canada. CMAJ. 1993;149:1657-1658
11. International Committee of Medical Journal Editors. Clinical trial registration: a statement from the International Committee of Medical Journal Editors [editorial]. Available at: http://www.icmje.org/clin_ trial.pdf. Accessed November 16, 2009
12. Askie L, Ghersi D, Simes J. Prospective registration of clinical trials. Aust J Physiother. 2006;52:237-239
13. D'Alonzo GE Jr. Clinical trial registration, a needed addition to the research process. J Am Osteopath Assoc. 2004;104:409-410
14. International Journal of Paediatric Dentistry. Author guidelines. Available at: http:// onlinelibrary.wiley.com/journal/ 10.1111/(ISSN)1365-263X/homepage/ ForAuthors.html.
15. Journal of Dentistry. Author guidelines. Available at: http://www.elsevier.com/wps/find/journaldescription.cws_home/30441/ authorinstructions. Accessed November 16, 2009
16. Eysenbach G. Tackling publication bias and selective reporting in health informatics research: register your eHealth trials in the International eHealth Studies Registry. J Med Internet Res. 2004;6:e35
17. Ewart R, Lausen H, Millian N. Undisclosed changes in outcomes in randomized controlled trials: an observational study. Ann Fam Med. 2009;7:542-546
18. Mathieu S, Boutron I, Moher D, et al. Comparison of registered and published primary outcomes in randomized controlled trials [erratum in: JAMA. 2009;302:1532]. JAMA. 2009;302:977-984
19. Macedo LG, Elkins MR, Maher CG, et al. There was evidence of convergent and construct validity of Physiotherapy Evidence Database quality scale for physiotherapy trials. J Clin Epidemiol. 2010;63: 920-925
20. Dwan K, Altman DG, Cresswell L, et al. Comparison of protocols and registry entries to published reports for randomised controlled trials. Cochrane Database Syst Rev. 2011;(1):MR000031
21. Chan AW, Hrobjartsson A, Haahr MT, et al. Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles. JAMA. 2004;291:2457-2465
22. Vedula SS, Bero L, Scherer RW, Dickersin K. Outcome reporting in industrysponsored trials of gabapentin for off-label use. N Engl J Med. 2009;361:1963-1971
23. Al-Marzouki S, Roberts I, Evans S, Marshall T. Selective reporting in clinical trials: analysis of trial protocols accepted by The Lancet. Lancet. 2008;372:201
24. Chan AW, Krleza-Jeric K, Schmid I, Altman DG. Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research. CMAJ. 2004;171: 735-740
25. Moseley AM, Elkins MR, Herbert RD, et al. Cochrane reviews used more rigorous methods than non-Cochrane reviews: survey of systematic reviews in physiotherapy. J Clin Epidemiol. 2009;62:1021-1030
26. Moseley AM, Sherrington C, Elkins MR, et al. Indexing of randomised controlled trials of physiotherapy interventions: a comparison of AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO and PubMed. Physiotherapy. 2009;95:151-156
27. Michaleff ZA, Costa LO, Moseley AM, et al. CENTRAL, PEDro, PubMed, and EMBASE are the most comprehensive databases indexing randomized controlled trials of physical therapy interventions. Phys Ther. 2011;91:190-197
28. de Morton NA. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother. 2009;55:129-133
29. Maher CG, Sherrington C, Herbert RD, et al. Reliability of the PEDro scale for rating quality of randomized controlled trials. Phys Ther. 2003;83:713-721
30. Juni P, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. JAMA. 1999;282: 1054-1060
31. Thomson Reuters. Journal citation reports, science edition 2010. Available at: http:// wokinfo.com/products_tools/analytical/ jcr/. Accessed September 21, 2011
32. International Society of Physiotherapy Journal Editors. Available at: http://www.wcpt. org/ispje/membership. Accessed July 9, 2012
33. Zarin DA, Tse T, Williams RJ, et al. The ClinicalTrials.gov results database: update and key issues. N Engl J Med. 2011;364: 852-860
34. Ross JS, Mulvey GK, Hines EM, et al. Trial publication after registration in Clinical Trials.Gov: a cross-sectional analysis. PLoS Med. 2009;6:e1000144
35. Craik RL, Maher C. Still "not satisfied"... yet [editorial]. Phys Ther. 2008;88:423-425
36. Elkins M. New initiatives in Journal of Physiotherapy. J Physiother. 2011;57:67-68
37. Harms M. Clinical trial registration. Physiotherapy. 2011;97:181
38. De Angelis CD, Drazen JM, Frizelle FA, et al. Is this clinical trial fully registered: a statement from the International Committee of Medical Journal Editors. N Engl J Med. 2005;352:2436-2438
39. Dwan K, Altman DG, Arnaiz JA, et al. Systematic review of the empirical evidence of study publication bias and outcome reporting bias. PLoS One. 2008;3:e3081.