Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle

Journal of Physiology

Volumn 591, Issue 3, 2013, Pages 719-729

  Murphy, R M ^a   Dutka, T L ^a   Horvath, D ^a   Bell, J R ^b   Delbridge, L M ^b   Lamb, G D ^a  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CALCIUM ION; CALPAIN; JUNCTOPHILIN 1; JUNCTOPHILIN 2; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; CALCIUM; JUNCTOPHILIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; ENZYME ACTIVATION; HEART DISEASE; HEART MUSCLE; IN VITRO STUDY; LEG MUSCLE; MUSCLE EXCITATION; MUSCLE ISCHEMIA; MUSCLE STRENGTH; MUSCLE TETANIC CONTRACTION; MUSCLE WEAKNESS; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; REPERFUSION INJURY; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; ADOLESCENT; ADULT; ANIMAL; C57BL MOUSE; HEART; HUMAN; LONG EVANS RAT; MALE; METABOLISM; MOUSE; PHYSIOLOGY; SPRAGUE DAWLEY RAT; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ADOLESCENT; ADULT; ANIMALS; CALCIUM; HEART; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE, SKELETAL; MYOCARDIUM; PROTEOLYSIS; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; YOUNG ADULT;

MLCS; MLOWN;

EID: 84873133391     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.243279     Document Type: Article

References (35)

1. Allen DG (2004). Skeletal muscle function: role of ionic changes in fatigue, damage and disease. Clin Exp Pharmacol Physiol 31, 485-493.
2. Balnave CD & Allen DG (1995). Intracellular calcium and force in single mouse muscle fibres following repeated contractions with stretch. J Physiol 488, 25-36.
3. Bellinger AM, Reiken S, Carlson C, Mongillo M, Liu X, Rothman L, Matecki S, Lacampagne A & Marks AR (2009). Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle. Nat Med 15, 325-330.
4. 2+] in the development of low frequency fatigue in mouse single muscle fibres. J Physiol 491, 813-824.
5. Corona BT, Balog EM, Doyle JA, Rupp JC, Luke RC & Ingalls CP (2010). Junctophilin damage contributes to early strength deficits and EC coupling failure after eccentric contractions. Am J Physiol Cell Physiol 298, C365-C376.
6. Dupont-Versteegden EE & McCarter RJ (1992). Differential expression of muscular dystrophy in diaphragm versus hindlimb muscles of mdx mice. Muscle Nerve 15, 1105-1110.
7. Gilchrist JS, Wang KK, Katz S & Belcastro AN (1992). Calcium-activated neutral protease effects upon skeletal muscle sarcoplasmic reticulum protein structure and calcium release. J Biol Chem 267, 20857-20865.
8. 2+ channel dihydropyridine receptors (DHPRs) in skeletal muscle. J Biol Chem 286, 43717-43725.
9. 2+ release from sarcoplasmic reticulum through silencing of junctophilin genes. Biophys J 90, 4418-4427.
10. 2+ release in calpain treated rabbit skinned muscle fibers. Biochem Biophys Res Commun 185, 713-718.
11. Ingalls CP, Warren GL, Williams JH, Ward CW & Armstrong RB (1998). E-C coupling failure in mouse EDL muscle after in vivo eccentric contractions. J Appl Physiol 85, 58-67.
12. Inomata M, Nomoto M, Hayashi M, Nakamura M, Imahori K & Kawashima S (1984). Comparison of low and high calcium requiring forms of the calcium-activated neutral protease (CANP) from rabbit skeletal muscle. J Biochem 95, 1661-1670.
13. Ito K, Komazaki S, Sasamoto K, Yoshida M, Nishi M, Kitamura K & Takeshima H (2001). Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1. J Cell Biol 154, 1059-1067.
14. Khairallah RJ, Shi G, Sbrana F, Prosser BL, Borroto C, Mazaitis MJ, Hoffman EP, Mahurkar A, Sachs F, Sun Y, Chen YW, Raiteri R, Lederer WJ, Dorsey SG & Ward CW (2012). Microtubules underlie dysfunction in duchenne muscular dystrophy. Sci Signal 5, ra56.
15. Kim KC, Caswell AH, Brunschwig JP & Brandt NR (1990). Identification of a new subpopulation of triad junctions isolated from skeletal muscle; morphological correlations with intact muscle. J Membr Biol 113, 221-235.
16. Komazaki S, Ito K, Takeshima H & Nakamura H (2002). Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1. FEBS Lett 524, 225-229.
17. 2+] alters sarcoplasmic reticulum function in skinned skeletal muscle fibres of the rat. J Physiol 519, 815-827.
18. 2+] abolishes excitation-contraction coupling in skeletal muscle fibres of rat and toad. J Physiol 489, 349-362.
19. Murphy RM, Snow RJ & Lamb GD (2006a). μ-Calpain and calpain-3 are not autolyzed with exhaustive exercise in humans. Am J Physiol Cell Physiol 290, C116-C122.
20. 2+ activation of diffusible and bound pools of μ-calpain in rat skeletal muscle. J Physiol 576, 595-612.
21. Murphy RM, Vissing K, Latchman H, Lamboley C, McKenna MJ, Overgaard K & Lamb GD (2011). Activation of skeletal muscle calpain-3 by eccentric exercise in humans does not result in its translocation to the nucleus or cytosol. J Appl Physiol 111, 1448-1458.
22. Ono Y, Kakinuma K, Torii F, Irie A, Nakagawa K, Labeit S, Abe K, Suzuki K & Sorimachi H (2004). Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3. J Biol Chem 279, 2761-2771.
23. Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD & Pessah IN (2007). Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem 282, 8667-8677.
24. +-ATPase are due to the activation of calpain in the heart. Can J Physiol Pharmacol 88, 388-397.
25. +-ATPase in ischemia-reperfused heart may be mediated through oxidative stress. Can J Physiol Pharmacol 90, 249-260.
26. Takeshima H, Komazaki S, Nishi M, Iino M & Kangawa K (2000). Junctophilins: a novel family of junctional membrane complex proteins. Mol Cell 6, 11-22.
27. van Oort RJ, Garbino A, Wang W, Dixit SS, Landstrom AP, Gaur N, De Almeida AC, Skapura DG, Rudy Y, Burns AR, Ackerman MJ & Wehrens XH (2011). Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation 123, 979-988.
28. 2+ concentration during contractions. Am J Physiol Cell Physiol 290, C1199-C1208.
29. 2+-induced disruption of excitation-contraction coupling in mammalian skeletal muscle fibers. Am J Physiol Cell Physiol 296, C1115-C1122.
30. Warren GL, Lowe DA, Hayes DA, Karwoski CJ, Prior BM & Armstrong RB (1993). Excitation failure in eccentric contraction-induced injury of mouse soleus muscle. J Physiol 468, 487-499.
31. Whitehead NP, Yeung EW, Froehner SC & Allen DG (2010). Skeletal muscle NADPH oxidase is increased and triggers stretch-induced damage in the mdx mouse. PloS One 5, e15354.
32. Woods CE, Novo D, DiFranco M & Vergara JL (2004). The action potential-evoked sarcoplasmic reticulum calcium release is impaired in mdx mouse muscle fibres. J Physiol 557, 59-75.
33. i and muscle damage in the mdx mouse. J Physiol 562, 367-380.
34. 2+ entry and cytoskeletal damage following eccentric contractions in mouse skeletal muscle. J Appl Physiol 112, 2077-2086.
35. Zhang BT, Yeung SS, Allen DG, Qin L & Yeung EW (2008). Role of the calcium-calpain pathway in cytoskeletal damage after eccentric contractions. J Appl Physiol 105, 352-357.