Anti-ulcer activity of sandalwood (Santalum album L.) stem hydro-alcoholic extract in three gastric-ulceration models of wistar rats;Actividad anti-ulcerosa del tallo de sándalo (santalum album L.) en extractos hidro-alcoholicos en tres modelos de ulceración gástrica de ratas wistar

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas

Volumn 12, Issue 1, 2013, Pages 81-91

  Ahmed, Nazeer ^a   Ali Khan, Mohammed Safwan ^b,c   Mat Jais, Abdul Manan ^c   Mohtarrudin, Norhafizah ^c   Ranjbar, Maryam ^d   Amjad, Mohammed Shujauddin ^e   Nagaraju, Bee ^a   Faraz, Mohammed ^a   Pathan, Faiyaz ^a   Chincholi, Anand ^a  

^a Nargund College of Pharmacy   (India)

^b Anwarul Uloom College of Pharmacy   (India)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^d UNIVERSITY OF MALAYA   (Malaysia)

^e Nizam Institute of Pharmacy and Research Center   (India)

Author keywords

Anti ulcer activity; Hydro alcoholic extract from S. album stem (SASE)

Indexed keywords

ALCOHOL; HISTAMINE H2 RECEPTOR ANTAGONIST; INDOMETACIN; OMEPRAZOLE; PLANT EXTRACT; PROTON PUMP INHIBITOR; RANITIDINE; SANTALUM ALBUM EXTRACT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIULCER ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG POTENCY; FEMALE; HISTOPATHOLOGY; IN VIVO STUDY; MALE; MEDICINAL PLANT; NONHUMAN; PLANT STEM; RAT; SANTALUM ALBUM; STOMACH PROTECTION; STOMACH ULCER; WATER IMMERSION;

EID: 84873132962     PISSN: None     EISSN: 07177917     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Asuzu IU, Onu, OU. 1990. Anti-ulcer activity of the ethanolic extract of Combretum dolicopetalum root. Int J Crude Drug Res 28: 27-32.
2. Bandyopadhyay D, Biswas K, Bhattacharyya M, Reiter RJ, Banerjee RK. 2002. Involvement of reactive oxygen species in gastric ulceration: Protection by melatonin. Indian J Exp Biol 40: 693-705.
3. Benencia F, Courrèges MC. 1999. Antiviral activity of sandalwood oil against Herpes simplex viruses-1 and -2. Phytomedicine 6: 119-123.
4. Bighetti AE, Antonio MA, Kohn LK, Rehder VLG, Foglio MA, Possenti A, Vilela L, Carvalho JE. 2005. Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz Bip. Phytomedicine 12: 72-77.
5. Borrelli F, Izzo AA. 2000. The plant kingdom as a source of anti-ulcer remedies. Phytother Res 14: 581-591.
6. Chaumont JP, Bardey I. 1989. Activities Antifongques In-Vitro de Sept Huiles Essentielles. Fitoterapia 60: 263-266.
7. Desai VB, Hirenath RD. 1991. Pharmacological Screening of HESP and Sandalwood oil. Indian Perfumer 35: 69-70.
8. Dharmani P, Palit G. 2006. Exploring Indian medicinal plants for anti-ulcer activity. Indian J Pharmacol 38: 95-99.
9. 2-Receptor antagonists-Standard therapy for acid-peptic diseases. N Engl J Med 323: 1672-1680.
10. Franko TG, Richter JE. 1998. Proton-pump inhibitors for gastric acid related disease. Cleve Clin J Med 65: 27-34.
11. Guo SK, Cheng KJ, Weng WL, Zhang WQ, Yu YQ. 1983. Immediate effect of Kuan-Xiong aerosols in the treament of anginal attacks. Planta Med 47: 116.
12. Harborne JB. 1978. Phytochemical methods. 3rd Ed., Chapman and Hall, London, UK.
13. Hoogerwerf WA, Pasricha PJ. 2001. Agents used for control of gastric acidity and treatment of peptic ulcers and gastroesophageal reflux disease. In: Hardman JG, Limbird LE, Goodman Gilman A, Editors. Goodman and Gilman. The Pharmacological Basis of Therapeutics. 10th Ed. McGraw-Hill Publishers, New York, USA.
14. Jagetia GC, Baliga MS. 2004. Evaluation of Nitric Oxide scavenging activity of certain Indian medicinal plants in-vitro: a preliminary study. J Med Food 7: 343-348.
15. Jamal A, Siddiqui A, Tajuddin Jafri MA. 2006. A review on gastric ulcer remedies used in Unani System of Medicine. Nat Prod Rad 5: 153-159.
16. Kaur, M. 2005. Skin cancer Chemopreventive agent, a-santalol induces apoptotic death of Human Epidermoid carcinoma A431 cells via caspase activation with dissipation of mitochondrial membrane and cytochrome-C release. Carcinogenesis 26: 369-380.
17. Khan MSA, Hussain SA, Mat Jais AM, Zakaria ZA, Khan M. 2011. Anti-ulcer activity of Ficus religiosa stem bark ethanolic extract in rats. J Med Plants Res 5: 354-359.
18. Khandelwal KR. 2004. Practical Pharmacognosy. 12th Ed., Nirali Prakashan, Pune, India.
19. Kirtikar KR, Basu BD. 1933. Santalum album. Indian Medicinal Plants, Vol.4, 2nd Ed., Basu L.M., Allahabad, India.
20. Kokate CK, Purohit AP, Gokhale SB. 2007. Pharmacognosy, 39th Ed., Nirali Prakashan, Pune, India.
21. Kulkarni MP, Juveka AR. 2008. Attenuation of acute and chronic restraint stress induced perturbations in experimental animals by Nelumbo nucifera Gaertn. Indian J Pharma Sci 70: 327-332.
22. Kulkarni SK, Goel RK. 1996. Gastric anti-ulcer activity of UL-409 in rats. Indian J Exp Biol 34: 683-688.
23. Majumdar DK. 1999. Evaluation of gastric anti-ulcer activity of fixed oil of Ocimum sanctum. J Ethnopharmacol 65: 13-19.
24. Mitra SK, Gopumadhavan S, Hemavathi TS, Muralidhar TS, Venkataranganna MV. 1996. Protective effect of UL-409, herbal formulation against physical and chemical factor induced gastric and duodenal ulcer in experimental animals. J Ethnopharmacol 52: 165-169.
25. Mrinal K. 1985. Clinical evaluation an indigenous herbal eyedrop preparation (a preliminary report). Indian Pract 38: 1149-1153.
26. Ochi T, Shibata H, Higuti T, Kodama KH, Kusumi T, Takaishi Y. 2005. Anti-Helicobacter pylori compounds from Santalum album. J Nat Prod 68: 819-824.
27. OECD Guidelines for the Testing of Chemicals. 2010. Test no. 423: Acute oral toxicity -Acute Toxic Class Method, 1: 1-14.
28. Parnaham MJ, Brune K. 1987. Therapeutic control of inflammatory diseases. Agents and Actions 21 (3): 232-34.
29. Peters MN, Richardson CT. 1983. Stressful life events, acid hypersecretion and ulcer disease. Gastroenterology 84: 114-119.
30. Phillipson M, Atuma C, Henriksnas J, Holm A. 2002. The importance of mucus layers and bicarbonate transport in preservation of gastric juxtamucosal pH. Am J Physiol-Gastrointest Liver Physiol 282: G211-G219.
31. Rates SM. 2001. Plants as source of drugs. Toxicon 39: 603-613.
32. Reilly JP. 1999. Safety profile of the proton-pump inhibitors. Am J Health Syst Pharm 56: S11-S17.
33. Samuelsson G. 1999. Drugs of Natural Origin. Swedish Pharmaceutical Press: Sweden.
34. Sandalwood Research Newsletter. 2006. ISSN 1321-0022 X Issue 21 March. http://www.jcu.edu.au/mbil/srn/Issues/SRN%20021.pdf (Consulted December 31, 2012)
35. Scartezzini P, Speroni E. 2000. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 71: 23-43.
36. Shankaranaryana KH, Parathasarthi K. 1985. HESP: A new essential oil from the acid hydrolysis of spent sandalwood. Perfumer & Flavorist 10: 60-61.
37. Shankaranaryana KH. 1986. Antibacterial activity of Sandal bark Tannins against Staphylococcus aureus. Van Vigyan 24: 120-121.
38. Shankaranarayana KH, Kamala BS. 1989. Six new essential oils from waste plant material. Indian Perfumer 33: 40-43.
39. Shay H, Komarov SA, Fele SS, Meranze D, Gruenstein H, Siplet H. 1945. A simple method for uniform production of gastric ulceration in rat. Gastroenterology 5: 43-46.
40. Sindhu RK, Upma, Kumar A, Arora S. 2010. Santalum album Linn: A review on Morphology, Phytochemistry and Pharmacological aspects. Intl J PharmTech Res 2: 914-919.
41. Sivaramakrishnan VR, Shankaranarayana KH. 1990. Investigation on the insecticidal properties of plant extractives-I testing of new medicinal oils, HESP from spent sandalwood powder on insects. Science & Culture 56: 124-127.
42. Soll AH. 1990. Pathogenesis of peptic ulcers and implication for therapy. N Engl J Med 322: 909-916.
43. Surendra S. 1999. Evaluation of gastric anti-ulcer activity of fixed oil of tulsi and possible mechanism. Indian J Exp Biol 36: 253-257.
44. Valle DL. 2005. Peptic ulcer diseases and related disorders. In: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, Editors. Harrison's principles of internal medicine. 16th Ed. McGraw-Hill Publisher, New York, USA.
45. Vedavyasa S. 1999. Gastric mucosal cellular changes induced by indomethacin male albino rats. Indian J Exp Biol 37: 365-369.
46. Venkataranganna MV, Gopumadhavan S, Sundaram R, Mitra SK. 1998. Evaluation of possible mechanism of anti-ulcerogenic activity of UL-409, a herbal preparation. J Ethnopharmacol 63: 187-192.
47. Vogel HJ. 2008. Drug Discovery and Evaluation: Pharmacological assays. 3rd Ed. Springer Publisher, New York, USA.
48. Wallace JL. 2008. Prostaglandins, NSAIDs, and gastric mucosal protection: Why doesn't the stomach digest itself? Physiol Rev 88: 1547-1565.