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Volumn 31, Issue 2, 2013, Pages 140-144

The etiology of treatment-related lymphopenia in patients with malignant gliomas: Modeling radiation dose to circulating lymphocytes explains clinical observations and suggests methods of modifying the impact of radiation on immune cells

Author keywords

Brain Radiation; Glioblastoma; High Grade Gliomas; Lymphocytes; Lymphopenia; Normal Tissue Toxicity; Survival

Indexed keywords

GLUCOCORTICOID; TEMOZOLOMIDE;

EID: 84873129162     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2012.762780     Document Type: Article
Times cited : (327)

References (17)
  • 1
    • 0037961043 scopus 로고    scopus 로고
    • Pneumocystis carinii pneumonia in HIV negative patients with primary brain tumors
    • DOI 10.1023/A:1024217527650
    • Mahindra AK, Grossman SA. Pneumocystis carinii pneumonia in HIV negative patients with primary brain tumors. J Neurooncol 2003;63(3):263-270. (Pubitemid 36874010)
    • (2003) Journal of Neuro-Oncology , vol.63 , Issue.3 , pp. 263-270
    • Mahindra, A.K.1    Grossman, S.A.2
  • 2
    • 77953010335 scopus 로고    scopus 로고
    • Emergence of cytomegalovirus disease in patients receiving temozolomide: Report of two cases and literature review
    • doi: 10.1086/653011
    • Meije Y, Lizasoain M, Garcia-Reyne A, et al. Emergence of cytomegalovirus disease in patients receiving temozolomide: report of two cases and literature review. Clin Infect Dis 2010;50(12):e73-e76. doi: 10.1086/653011.
    • (2010) Clin Infect Dis , vol.50 , Issue.12
    • Meije, Y.1    Lizasoain, M.2    Garcia-Reyne, A.3
  • 4
    • 80051693219 scopus 로고    scopus 로고
    • Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide
    • doi: 10.1158/1078-0432.CCR-11-0774; 10.1158/1078-0432.CCR- 11-0774
    • Grossman SA, Ye X, Lesser G, et al. Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide. Clin Cancer Res 2011;17(16):5473-5480. doi: 10.1158/1078-0432.CCR-11-0774; 10.1158/1078-0432. CCR- 11-0774.
    • (2011) Clin Cancer Res , vol.17 , Issue.16 , pp. 5473-5480
    • Grossman, S.A.1    Ye, X.2    Lesser, G.3
  • 5
    • 22144485870 scopus 로고    scopus 로고
    • Primary brain tumors treated with steroids and radiotherapy: Low CD4 counts and risk of infection
    • DOI 10.1016/j.ijrobp.2004.12.085, PII S0360301605001410
    • Hughes MA, Parisi M, Grossman S, Kleinberg L. Primary brain tumors treated with steroids and radiotherapy: Low CD4 counts and risk of infection. Int J Radiat Oncol Biol Phys 2005;62(5):1423-1426. doi: 10.1016/j.ijrobp.2004. 12.085. (Pubitemid 40982064)
    • (2005) International Journal of Radiation Oncology Biology Physics , vol.62 , Issue.5 , pp. 1423-1426
    • Hughes, M.A.1    Parisi, M.2    Grossman, S.3    Kleinberg, L.4
  • 6
    • 84873168573 scopus 로고
    • Some theoretical considerations on the present status of roentgen therapy
    • Shohan J. Some theoretical considerations on the present status of roentgen therapy. N Engl J Med 1916;175:321-327.
    • (1916) N Engl J Med , vol.175 , pp. 321-327
    • Shohan, J.1
  • 7
    • 0017804612 scopus 로고
    • Analysis of treatment in childhood leukemia. IV. The critical association between dose fractionation and immunosuppression induced by cranial irradiation
    • MacLennan IC, Kay HE. Analysis of treatment in childhood leukemia. IV. The critical association between dose fractionation and immunosuppression induced by cranial irradiation. Cancer 1978;41(1):108-111. (Pubitemid 8286417)
    • (1978) Cancer , vol.41 , Issue.1 , pp. 108-111
    • MacLennan, I.C.M.1    Kay, H.E.M.2
  • 8
    • 0015714053 scopus 로고
    • The development of lymphopenia in uremic patients undergoing extracorporeal irradiation of the blood with portable beta units
    • Weeke E. The development of lymphopenia in uremic patients undergoing extracorporeal irradiation of the blood with portable beta units. Radiat Res 1973;56(3):554-559.
    • (1973) Radiat Res , vol.56 , Issue.3 , pp. 554-559
    • Weeke, E.1
  • 9
    • 84975326622 scopus 로고    scopus 로고
    • 21st edition,New York, NY: Lange Medical Books McGraw-Hill
    • Ganong W, (ed). Review ofMedical Physiology, 21st edition,New York, NY: Lange Medical Books, McGraw-Hill, 2003.
    • (2003) Review OfMedical Physiology
    • Ganong, W.1
  • 10
    • 0025007730 scopus 로고
    • Radiosensitivity of CD4 or CD8 positive human T-lymphocytes by an in vitro colony formation assay
    • DOI 10.2307/3577549
    • Nakamura N, Kusunoki Y, Akiyama M. Radiosensitivity of CD4 or CD8 positive human T-lymphocytes by an in vitro colony formation assay. Radiat Res 1990;123(2):224-227. (Pubitemid 20262304)
    • (1990) Radiation Research , vol.123 , Issue.2 , pp. 224-227
    • Nakamura, N.1    Kusunoki, Y.2    Akiyama, M.3
  • 11
    • 0000091853 scopus 로고
    • Qualitiative and quantitative reactions of lymphocytes to x-rays
    • Schrek R. Qualitiative and quantitative reactions of lymphocytes to x-rays. Ann New York Acad Sci 1961;95:839-48.
    • (1961) Ann New York Acad Sci , vol.95 , pp. 839-848
    • Schrek, R.1
  • 14
    • 84873130845 scopus 로고    scopus 로고
    • Degree of chemoradiationassociated lymphopenia is related to radiation field size in patients with locally advanced pancreatic cancer
    • Wild AT, Yovino S, Smith JA, et al. Degree of chemoradiationassociated lymphopenia is related to radiation field size in patients with locally advanced pancreatic cancer. Annu. Meeting Am Radium Soc 2012.
    • (2012) Annu. Meeting Am Radium Soc
    • Wild, A.T.1    Yovino, S.2    Smith, J.A.3
  • 15
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • doi: 10.1056/NEJMoa1001294
    • Kantoff PW, Higano CS, Shore ND, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010;363(5):411-422. doi: 10.1056/NEJMoa1001294.
    • (2010) N Engl J Med , vol.363 , Issue.5 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 16
    • 77950258677 scopus 로고    scopus 로고
    • Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: Lymphocyte count after 2 doses correlates with survival
    • doi: 10.1002/cncr.24951
    • Ku GY, Yuan J, Page DB, et al. Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survival. Cancer 2010;116(7):1767-1775. doi: 10.1002/cncr.24951.
    • (2010) Cancer , vol.116 , Issue.7 , pp. 1767-1775
    • Ku, G.Y.1    Yuan, J.2    Page, D.B.3
  • 17
    • 67649645232 scopus 로고    scopus 로고
    • Modelling carcinogenesis after radiotherapy using poisson statistics: Implications for IMRT, protons and ions
    • doi: 10.1088/0952- 4746/29/2A/S10
    • Jones B. Modelling carcinogenesis after radiotherapy using poisson statistics: implications for IMRT, protons and ions. J Radiol Prot 2009;29(2A):A143-A157. doi: 10.1088/0952- 4746/29/2A/S10.
    • (2009) J Radiol Prot , vol.29 , Issue.2
    • Jones, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.