메뉴 건너뛰기




Volumn 9, Issue 3, 2013, Pages 5421-5430

Hydrogels in calcium phosphate moldable and injectable bone substitutes: Sticky excipients or advanced 3-D carriers?

Author keywords

Bone; Calcium phosphates; Composite; Hydrogel

Indexed keywords

BONE; CALCIUM PHOSPHATE; CELL ENGINEERING; HYDROGELS; TISSUE ENGINEERING;

EID: 84873124207     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.11.022     Document Type: Review
Times cited : (78)

References (106)
  • 1
    • 84891728471 scopus 로고    scopus 로고
    • Bone grafts-a US market report, < http://www.prweb.com/releases/bone- grafts/standard-bone-allografts/prweb8953883.htm >; 2011.
    • (2011) Bone Grafts-a US Market Report
  • 2
    • 77649137075 scopus 로고    scopus 로고
    • Autologous bone graft: Properties and techniques
    • H.C. Pape, A. Evans, and P. Kobbe Autologous bone graft: properties and techniques J Orthop Trauma 24 Suppl. 1 2010 S36 S40
    • (2010) J Orthop Trauma , vol.24 , Issue.SUPPL. 1
    • Pape, H.C.1    Evans, A.2    Kobbe, P.3
  • 4
    • 84873973425 scopus 로고    scopus 로고
    • Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies
    • Y.C. Chai Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies Acta Biomater 8 11 2012 3876 3887
    • (2012) Acta Biomater , vol.8 , Issue.11 , pp. 3876-3887
    • Chai, Y.C.1
  • 5
    • 0001117908 scopus 로고
    • Ueber Knochenplombierung (on bone sealing)
    • H. Dreesmann Ueber Knochenplombierung (on bone sealing) Beitr Klin Chir 9 1892 804 810
    • (1892) Beitr Klin Chir , vol.9 , pp. 804-810
    • Dreesmann, H.1
  • 7
    • 77957245124 scopus 로고    scopus 로고
    • Design of ceramic-based cements and putties for bone graft substitution
    • M. Bohner Design of ceramic-based cements and putties for bone graft substitution Eur Cell Mater 20 2010 1 12
    • (2010) Eur Cell Mater , vol.20 , pp. 1-12
    • Bohner, M.1
  • 8
    • 78650722339 scopus 로고    scopus 로고
    • Commentary: Deciphering the link between architecture and biological response of a bone graft substitute
    • M. Bohner, Y. Loosli, G. Baroud, and D. Lacroix Commentary: deciphering the link between architecture and biological response of a bone graft substitute Acta Biomater 7 2 2011 478 484
    • (2011) Acta Biomater , vol.7 , Issue.2 , pp. 478-484
    • Bohner, M.1    Loosli, Y.2    Baroud, G.3    Lacroix, D.4
  • 9
    • 78049415804 scopus 로고    scopus 로고
    • A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair
    • A.J. Wagoner Johnson, and B.A. Herschler A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair Acta Biomater 7 1 2011 16 30
    • (2011) Acta Biomater , vol.7 , Issue.1 , pp. 16-30
    • Wagoner Johnson, A.J.1    Herschler, B.A.2
  • 12
    • 0025965343 scopus 로고
    • In vitro properties of a chitosan-bonded hydroxyapatite bone-filling paste
    • M. Ito In vitro properties of a chitosan-bonded hydroxyapatite bone-filling paste Biomaterials 12 1 1991 41 45
    • (1991) Biomaterials , vol.12 , Issue.1 , pp. 41-45
    • Ito, M.1
  • 14
    • 0032521108 scopus 로고    scopus 로고
    • In vitro evaluation of a new injectable calcium phosphate material
    • DOI 10.1002/(SICI)1097-4636(19980315)39:4<660::AID-JBM22>3.0.CO;2-9
    • G. Grimandi, P. Weiss, F. Millot, and G. Daculsi In vitro evaluation of a new injectable calcium phosphate material J Biomed Mater Res 39 4 1998 660 666 (Pubitemid 28079731)
    • (1998) Journal of Biomedical Materials Research , vol.39 , Issue.4 , pp. 660-666
    • Grimandi, G.1    Weiss, P.2    Millot, F.3    Daculsi, G.4
  • 16
    • 0032775019 scopus 로고    scopus 로고
    • Injectable bone substitute using a hydrophilic polymer
    • DOI 10.1016/S8756-3282(99)00146-5, PII S8756328299001465
    • P. Weiss, O. Gauthier, J.M. Bouler, G. Grimandi, and G. Daculsi Injectable bone substitute using a hydrophilic polymer Bone 25 Suppl. 2 1999 67S 70S (Pubitemid 29333183)
    • (1999) Bone , vol.25 , Issue.SUPPL. 1
    • Weiss, P.1    Gauthier, O.2    Bouler, J.-M.3    Grimandi, G.4    Daculsi, G.5
  • 17
    • 0035808170 scopus 로고    scopus 로고
    • In vivo bone formation by human bone marrow stromal cells: Effect of carrier particle size and shape
    • DOI 10.1002/1097-0290(20010105)72:1<96::AID-BIT13>3.0.CO;2-A
    • M.H. Mankani, S.A. Kuznetsov, B. Fowler, A. Kingman, and P.G. Robey In vivo bone formation by human bone marrow stromal cells: effect of carrier particle size and shape Biotechnol Bioeng 72 1 2001 96 107 (Pubitemid 32085898)
    • (2001) Biotechnology and Bioengineering , vol.72 , Issue.1 , pp. 96-107
    • Mankani, M.H.1    Kuznetsov, S.A.2    Fowler, B.3    Kingman, A.4    Robey, P.G.5
  • 19
    • 0031638368 scopus 로고    scopus 로고
    • The material bone: Structure-mechanical function relations
    • S. Weiner, and H.D. Wagner The material bone: structure-mechanical function relations Annu Rev Mater Sci 28 1 1998 271 298 (Pubitemid 128631421)
    • (1998) Annual Review of Materials Science , vol.28 , Issue.1 , pp. 271-298
    • Weiner, S.1    Wagner, H.D.2
  • 20
    • 0028129454 scopus 로고
    • Modulation of crystal formation by bone phosphoproteins: Role of glutamic acid-rich sequences in the nucleation of hydroxyapatite by bone sialoprotein
    • G.K. Hunter, and H.A. Goldberg Modulation of crystal formation by bone phosphoproteins: role of glutamic acid-rich sequences in the nucleation of hydroxyapatite by bone sialoprotein Biochem J 302 Pt 1 1994 175 179 (Pubitemid 24256351)
    • (1994) Biochemical Journal , vol.302 , Issue.1 , pp. 175-179
    • Hunter, G.K.1    Goldberg, H.A.2
  • 21
    • 14944385532 scopus 로고    scopus 로고
    • Mineralization of synthetic polymer scaffolds: A bottom-up approach for the development of artificial bone
    • DOI 10.1021/ja043776z
    • J. Song, V. Malathong, and C.R. Bertozzi Mineralization of synthetic polymer scaffolds: a bottom-up approach for the development of artificial bone J Am Chem Soc 127 10 2005 3366 3372 (Pubitemid 40365275)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.10 , pp. 3366-3372
    • Song, J.1    Malathong, V.2    Bertozzi, C.R.3
  • 22
    • 14644413519 scopus 로고    scopus 로고
    • Supramolecular assembly of amelogenin nanospheres into birefringent microribbons
    • DOI 10.1126/science.1105675
    • C. Du, G. Falini, S. Fermani, C. Abbott, and J. Moradian-Oldak Supramolecular assembly of amelogenin nanospheres into birefringent microribbons Science 307 5714 2005 1450 1454 (Pubitemid 40321938)
    • (2005) Science , vol.307 , Issue.5714 , pp. 1450-1454
    • Du, C.1    Falini, G.2    Fermani, S.3    Abbott, C.4    Moradian-Oldak, J.5
  • 23
    • 47249144651 scopus 로고    scopus 로고
    • Anions bonded on the supramolecular hydrogel surface as the growth center of biominerals
    • N. Shi, G. Yin, M. Han, and Z. Xu Anions bonded on the supramolecular hydrogel surface as the growth center of biominerals Colloids Surf B Biointerfaces 66 1 2008 84 89
    • (2008) Colloids Surf B Biointerfaces , vol.66 , Issue.1 , pp. 84-89
    • Shi, N.1    Yin, G.2    Han, M.3    Xu, Z.4
  • 24
    • 0035255306 scopus 로고    scopus 로고
    • Is there a chemical interaction between calcium phosphates and hydroxypropylmethylcellulose (HPMC) in organic/inorganic composites?
    • S.V. Dorozhkin Is there a chemical interaction between calcium phosphates and hydroxypropylmethylcellulose (HPMC) in organic/inorganic composites? J Biomed Mater Res 54 2 2001 247 255
    • (2001) J Biomed Mater Res , vol.54 , Issue.2 , pp. 247-255
    • Dorozhkin, S.V.1
  • 25
    • 0033622839 scopus 로고    scopus 로고
    • Crystal polymer interaction with new injectable bone substitute; SEM and Hr TEM study
    • G. Daculsi, R. Rohanizadeh, P. Weiss, and J.M. Bouler Crystal polymer interaction with new injectable bone substitute; SEM and Hr TEM study J Biomed Mater Res 50 1 2000 1 7
    • (2000) J Biomed Mater Res , vol.50 , Issue.1 , pp. 1-7
    • Daculsi, G.1    Rohanizadeh, R.2    Weiss, P.3    Bouler, J.M.4
  • 27
    • 79959825584 scopus 로고    scopus 로고
    • Calcium phosphates compounds in conjunction with hydrogel as carrier for BMP-2: A study on ectopic bone formation in rats
    • G. Hulsart-Billström Calcium phosphates compounds in conjunction with hydrogel as carrier for BMP-2: a study on ectopic bone formation in rats Acta Biomater 7 8 2011 3042 3049
    • (2011) Acta Biomater , vol.7 , Issue.8 , pp. 3042-3049
    • Hulsart-Billström, G.1
  • 28
    • 0037122675 scopus 로고    scopus 로고
    • Hydrogels for biomedical applications
    • DOI 10.1016/S0169-409X(01)00239-3, PII S0169409X01002393
    • A.S. Hoffman Hydrogels for biomedical applications Adv Drug Deliv Rev 54 1 2002 3 12 (Pubitemid 34081178)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.1 , pp. 3-12
    • Hoffman, A.S.1
  • 29
    • 0037122788 scopus 로고    scopus 로고
    • Novel crosslinking methods to design hydrogels
    • DOI 10.1016/S0169-409X(01)00240-X, PII S0169409X0100240X
    • W.E. Hennink, and C.F. van Nostrum Novel crosslinking methods to design hydrogels Adv Drug Deliv Rev 54 1 2002 13 36 (Pubitemid 34075312)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.1 , pp. 13-36
    • Hennink, W.E.1    Van Nostrum, C.F.2
  • 30
    • 77957706043 scopus 로고    scopus 로고
    • Designing biomimetic scaffolds for bone regeneration: Why aim for a copy of mature tissue properties if nature uses a different approach?
    • B.M. Willie Designing biomimetic scaffolds for bone regeneration: why aim for a copy of mature tissue properties if nature uses a different approach? Soft Matter 6 20 2010 4976 4987
    • (2010) Soft Matter , vol.6 , Issue.20 , pp. 4976-4987
    • Willie, B.M.1
  • 31
    • 56249112974 scopus 로고    scopus 로고
    • Influence of scaffold stiffness on subchondral bone and subsequent cartilage regeneration in an ovine model of osteochondral defect healing
    • K. Schlichting Influence of scaffold stiffness on subchondral bone and subsequent cartilage regeneration in an ovine model of osteochondral defect healing Am J Sports Med 36 12 2008 2379 2391
    • (2008) Am J Sports Med , vol.36 , Issue.12 , pp. 2379-2391
    • Schlichting, K.1
  • 32
    • 77954819260 scopus 로고    scopus 로고
    • Characterization of polymeric solutions as injectable vehicles for hydroxyapatite microspheres
    • S.M. Oliveira Characterization of polymeric solutions as injectable vehicles for hydroxyapatite microspheres AAPS PharmSciTech 11 2 2010 852 858
    • (2010) AAPS PharmSciTech , vol.11 , Issue.2 , pp. 852-858
    • Oliveira, S.M.1
  • 33
    • 77954534670 scopus 로고    scopus 로고
    • The stability mechanisms of an injectable calcium phosphate ceramic suspension
    • A. Fatimi, J.F. Tassin, M.A. Axelos, and P. Weiss The stability mechanisms of an injectable calcium phosphate ceramic suspension J Mater Sci Mater Med 21 6 2010 1799 1809
    • (2010) J Mater Sci Mater Med , vol.21 , Issue.6 , pp. 1799-1809
    • Fatimi, A.1    Tassin, J.F.2    Axelos, M.A.3    Weiss, P.4
  • 34
    • 84860247542 scopus 로고    scopus 로고
    • Evaluation of an anorganic bovine-derived mineral with P-15 hydrogel bone graft: Preliminary study in a rabbit cranial bone model
    • S. Matos, F. Guerra, J.T. Krauser, H. Figueiredo, J.P. Marcelino, and M. Sanz Evaluation of an anorganic bovine-derived mineral with P-15 hydrogel bone graft: preliminary study in a rabbit cranial bone model Clin Oral Implants Res 23 6 2012 698 705
    • (2012) Clin Oral Implants Res , vol.23 , Issue.6 , pp. 698-705
    • Matos, S.1    Guerra, F.2    Krauser, J.T.3    Figueiredo, H.4    Marcelino, J.P.5    Sanz, M.6
  • 35
    • 77951170997 scopus 로고    scopus 로고
    • Bone repair by cell-seeded 3D-bioplotted composite scaffolds made of collagen treated tricalciumphosphate or tricalciumphosphate-chitosan-collagen hydrogel or PLGA in ovine critical-sized calvarial defects
    • K. Haberstroh Bone repair by cell-seeded 3D-bioplotted composite scaffolds made of collagen treated tricalciumphosphate or tricalciumphosphate- chitosan-collagen hydrogel or PLGA in ovine critical-sized calvarial defects J Biomed Mater Res B Appl Biomater 93B 2 2010 520 530
    • (2010) J Biomed Mater Res B Appl Biomater , vol.93 B , Issue.2 , pp. 520-530
    • Haberstroh, K.1
  • 36
    • 48449087982 scopus 로고    scopus 로고
    • Mechanisms underlying the limited injectability of hydraulic calcium phosphate paste
    • M. Habib, G. Baroud, F. Gitzhofer, and M. Bohner Mechanisms underlying the limited injectability of hydraulic calcium phosphate paste Acta Biomater 4 5 2008 1465 1471
    • (2008) Acta Biomater , vol.4 , Issue.5 , pp. 1465-1471
    • Habib, M.1    Baroud, G.2    Gitzhofer, F.3    Bohner, M.4
  • 37
    • 84929949613 scopus 로고    scopus 로고
    • Mechanisms underlying the limited injectability of hydraulic calcium phosphate paste. Part II: Particle separation study
    • M. Habib, G. Baroud, F. Gitzhofer, and M. Bohner Mechanisms underlying the limited injectability of hydraulic calcium phosphate paste. Part II: particle separation study Acta Biomater 6 1 2010 250 256
    • (2010) Acta Biomater , vol.6 , Issue.1 , pp. 250-256
    • Habib, M.1    Baroud, G.2    Gitzhofer, F.3    Bohner, M.4
  • 38
    • 84856519167 scopus 로고    scopus 로고
    • Evaluation of the ultrasonication process for injectability of hydraulic calcium phosphate pastes
    • M. Habib, G. Baroud, L. Galea, and M. Bohner Evaluation of the ultrasonication process for injectability of hydraulic calcium phosphate pastes Acta Biomater 8 3 2012 1164 1168
    • (2012) Acta Biomater , vol.8 , Issue.3 , pp. 1164-1168
    • Habib, M.1    Baroud, G.2    Galea, L.3    Bohner, M.4
  • 39
    • 7444269882 scopus 로고    scopus 로고
    • Injectability of calcium phosphate pastes
    • DOI 10.1016/j.biomaterials.2004.05.010, PII S0142961204004867
    • M. Bohner, and G. Baroud Injectability of calcium phosphate pastes Biomaterials 26 13 2005 1553 1563 (Pubitemid 39445378)
    • (2005) Biomaterials , vol.26 , Issue.13 , pp. 1553-1563
    • Bohner, M.1    Baroud, G.2
  • 40
    • 33748867211 scopus 로고    scopus 로고
    • Theoretical and experimental approach to test the cohesion of calcium phosphate pastes
    • M. Bohner, N. Doebelin, and G. Baroud Theoretical and experimental approach to test the cohesion of calcium phosphate pastes Eur Cell Mater 12 2006 26 35 (Pubitemid 44898110)
    • (2006) European Cells and Materials , vol.12 , pp. 26-35
    • Bohner, M.1    Doebelin, N.2    Baroud, G.3
  • 41
    • 84863326571 scopus 로고    scopus 로고
    • Injection of calcium phosphate pastes: Prediction of injection force and comparison with experiments
    • A. Fatimi, J.F. Tassin, J. Bosco, R. Deterre, M.A. Axelos, and P. Weiss Injection of calcium phosphate pastes: prediction of injection force and comparison with experiments J Mater Sci Mater Med 23 7 2012 1593 1603
    • (2012) J Mater Sci Mater Med , vol.23 , Issue.7 , pp. 1593-1603
    • Fatimi, A.1    Tassin, J.F.2    Bosco, J.3    Deterre, R.4    Axelos, M.A.5    Weiss, P.6
  • 43
    • 77951258132 scopus 로고    scopus 로고
    • Developments in injectable multiphasic biomaterials: The performance of microporous biphasic calcium phosphate granules and hydrogels
    • G. Daculsi, A.P. Uzel, P. Weiss, E. Goyenvalle, and E. Aguado Developments in injectable multiphasic biomaterials: the performance of microporous biphasic calcium phosphate granules and hydrogels J Mater Sci Mater Med 21 3 2010 855 861
    • (2010) J Mater Sci Mater Med , vol.21 , Issue.3 , pp. 855-861
    • Daculsi, G.1    Uzel, A.P.2    Weiss, P.3    Goyenvalle, E.4    Aguado, E.5
  • 44
    • 77956627196 scopus 로고    scopus 로고
    • Hydrogel/calcium phosphate composites require specific properties for three-dimensional culture of human bone mesenchymal cells
    • J. Sohier, P. Corre, P. Weiss, and P. Layrolle Hydrogel/calcium phosphate composites require specific properties for three-dimensional culture of human bone mesenchymal cells Acta Biomater 6 8 2010 2932 2939
    • (2010) Acta Biomater , vol.6 , Issue.8 , pp. 2932-2939
    • Sohier, J.1    Corre, P.2    Weiss, P.3    Layrolle, P.4
  • 45
    • 70349992956 scopus 로고    scopus 로고
    • Gelation studies of a cellulose-based biohydrogel: The influence of pH, temperature and sterilization
    • A. Fatimi, J.F. Tassin, R. Turczyn, M.A. Axelos, and P. Weiss Gelation studies of a cellulose-based biohydrogel: the influence of pH, temperature and sterilization Acta Biomater 5 9 2009 3423 3432
    • (2009) Acta Biomater , vol.5 , Issue.9 , pp. 3423-3432
    • Fatimi, A.1    Tassin, J.F.2    Turczyn, R.3    Axelos, M.A.4    Weiss, P.5
  • 46
    • 35348830480 scopus 로고    scopus 로고
    • Investigation of a thermoplastic polymeric carrier for bone tissue engineering using allogeneic mesenchymal stem cells in granular scaffolds
    • D. Mylonas, M.D. Vidal, I.J. De Kok, J.D. Moriarity, and L.F. Cooper Investigation of a thermoplastic polymeric carrier for bone tissue engineering using allogeneic mesenchymal stem cells in granular scaffolds J Prosthodont 16 6 2007 421 430
    • (2007) J Prosthodont , vol.16 , Issue.6 , pp. 421-430
    • Mylonas, D.1    Vidal, M.D.2    De Kok, I.J.3    Moriarity, J.D.4    Cooper, L.F.5
  • 47
    • 77049106676 scopus 로고    scopus 로고
    • Evaluation of bone regeneration with an injectable, in situ polymerizable Pluronic F127 hydrogel derivative combined with autologous mesenchymal stem cells in a goat tibia defect model
    • E. Lippens Evaluation of bone regeneration with an injectable, in situ polymerizable Pluronic F127 hydrogel derivative combined with autologous mesenchymal stem cells in a goat tibia defect model Tissue Eng A 16 2 2010 617 627
    • (2010) Tissue Eng A , vol.16 , Issue.2 , pp. 617-627
    • Lippens, E.1
  • 48
    • 84859378531 scopus 로고    scopus 로고
    • Injectable and thermosensitive PLGA-g-PEG hydrogels containing hydroxyapatite: Preparation, characterization and in vitro release behavior
    • G. Lin, L. Cosimbescu, N.J. Karin, and B.J. Tarasevich Injectable and thermosensitive PLGA-g-PEG hydrogels containing hydroxyapatite: preparation, characterization and in vitro release behavior Biomed Mater 7 2 2012 024107
    • (2012) Biomed Mater , vol.7 , Issue.2 , pp. 024107
    • Lin, G.1    Cosimbescu, L.2    Karin, N.J.3    Tarasevich, B.J.4
  • 49
    • 77449159999 scopus 로고    scopus 로고
    • Bone healing with an in situ-formed bioresorbable polyethylene glycol hydrogel membrane in rabbit calvarial defects
    • C.C. Humber Bone healing with an in situ-formed bioresorbable polyethylene glycol hydrogel membrane in rabbit calvarial defects Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109 3 2010 372 384
    • (2010) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.109 , Issue.3 , pp. 372-384
    • Humber, C.C.1
  • 50
    • 84855971046 scopus 로고    scopus 로고
    • Evaluation of a biodegradable synthetic hydrogel used as a guided bone regeneration membrane: An experimental study in dogs
    • D.S. Thoma, M.M. Dard, G.A. Halg, C.F. Ramel, C.H. Hammerle, and R.E. Jung Evaluation of a biodegradable synthetic hydrogel used as a guided bone regeneration membrane: an experimental study in dogs Clin Oral Implants Res 23 2 2012 160 168
    • (2012) Clin Oral Implants Res , vol.23 , Issue.2 , pp. 160-168
    • Thoma, D.S.1    Dard, M.M.2    Halg, G.A.3    Ramel, C.F.4    Hammerle, C.H.5    Jung, R.E.6
  • 52
    • 79953878870 scopus 로고    scopus 로고
    • Influence of different polymeric gels on the ectopic bone forming ability of an osteoinductive biphasic calcium phosphate ceramic
    • D. Barbieri, H. Yuan, F. de Groot, W.R. Walsh, and J.D. de Bruijn Influence of different polymeric gels on the ectopic bone forming ability of an osteoinductive biphasic calcium phosphate ceramic Acta Biomater 7 5 2011 2007 2014
    • (2011) Acta Biomater , vol.7 , Issue.5 , pp. 2007-2014
    • Barbieri, D.1    Yuan, H.2    De Groot, F.3    Walsh, W.R.4    De Bruijn, J.D.5
  • 53
    • 80053568285 scopus 로고    scopus 로고
    • An injectable bone substitute composed of beta-tricalcium phosphate granules, methylcellulose and hyaluronic acid inhibits connective tissue influx into its implantation bed in vivo
    • S. Ghanaati An injectable bone substitute composed of beta-tricalcium phosphate granules, methylcellulose and hyaluronic acid inhibits connective tissue influx into its implantation bed in vivo Acta Biomater 7 11 2011 4018 4028
    • (2011) Acta Biomater , vol.7 , Issue.11 , pp. 4018-4028
    • Ghanaati, S.1
  • 54
    • 58249136373 scopus 로고    scopus 로고
    • The in vivo degradation of a ruthenium labelled polysaccharide-based hydrogel for bone tissue engineering
    • S. Laïb The in vivo degradation of a ruthenium labelled polysaccharide-based hydrogel for bone tissue engineering Biomaterials 30 8 2009 1568 1577
    • (2009) Biomaterials , vol.30 , Issue.8 , pp. 1568-1577
    • Laïb, S.1
  • 55
    • 77954383096 scopus 로고    scopus 로고
    • Hyaluronic acid hydrogels with controlled degradation properties for oriented bone regeneration
    • J. Patterson, R. Siew, S.W. Herring, A.S.P. Lin, R. Guldberg, and P.S. Stayton Hyaluronic acid hydrogels with controlled degradation properties for oriented bone regeneration Biomaterials 31 26 2010 6772 6781
    • (2010) Biomaterials , vol.31 , Issue.26 , pp. 6772-6781
    • Patterson, J.1    Siew, R.2    Herring, S.W.3    Lin, A.S.P.4    Guldberg, R.5    Stayton, P.S.6
  • 56
    • 77954313439 scopus 로고    scopus 로고
    • Calcium phosphate biomaterials as bone drug delivery systems: A review
    • E. Verron, I. Khairoun, J. Guicheux, and J.M. Bouler Calcium phosphate biomaterials as bone drug delivery systems: a review Drug Discov Today 15 13-14 2010 547 552
    • (2010) Drug Discov Today , vol.15 , Issue.13-14 , pp. 547-552
    • Verron, E.1    Khairoun, I.2    Guicheux, J.3    Bouler, J.M.4
  • 57
    • 84865469020 scopus 로고    scopus 로고
    • Controlling the biological function of calcium phosphate bone substitutes with drugs
    • E. Verron, J.M. Bouler, and J. Guicheux Controlling the biological function of calcium phosphate bone substitutes with drugs Acta Biomater 2012
    • (2012) Acta Biomater
    • Verron, E.1    Bouler, J.M.2    Guicheux, J.3
  • 58
    • 84857784368 scopus 로고    scopus 로고
    • Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
    • S. Bose, and S. Tarafder Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review Acta Biomater 8 4 2012 1401 1421
    • (2012) Acta Biomater , vol.8 , Issue.4 , pp. 1401-1421
    • Bose, S.1    Tarafder, S.2
  • 59
    • 84865282959 scopus 로고    scopus 로고
    • Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration
    • P.S. Lienemann, M.P. Lutolf, and M. Ehrbar Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration Adv Drug Deliv Rev 64 12 2012 1078 1089
    • (2012) Adv Drug Deliv Rev , vol.64 , Issue.12 , pp. 1078-1089
    • Lienemann, P.S.1    Lutolf, M.P.2    Ehrbar, M.3
  • 60
    • 84865041045 scopus 로고    scopus 로고
    • Strategies for controlled delivery of growth factors and cells for bone regeneration
    • T.N. Vo, F.K. Kasper, and A.G. Mikos Strategies for controlled delivery of growth factors and cells for bone regeneration Adv Drug Deliv Rev 64 12 2012 1292 1309
    • (2012) Adv Drug Deliv Rev , vol.64 , Issue.12 , pp. 1292-1309
    • Vo, T.N.1    Kasper, F.K.2    Mikos, A.G.3
  • 61
    • 0002071012 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: From basic science to clinical applications
    • A.H. Reddi Bone morphogenetic proteins: from basic science to clinical applications J Bone Joint Surg Am 83A Suppl. 1 2001 S1 S6
    • (2001) J Bone Joint Surg Am , vol.83 A , Issue.SUPPL. 1
    • Reddi, A.H.1
  • 62
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • M.R. Urist Bone: formation by autoinduction Science 150 3698 1965 893 899
    • (1965) Science , vol.150 , Issue.3698 , pp. 893-899
    • Urist, M.R.1
  • 63
    • 0026090868 scopus 로고
    • Telopeptide-depleted bovine skin collagen as a carrier for bone morphogenetic protein
    • K. Takaoka, M. Koezuka, and H. Nakahara Telopeptide-depleted bovine skin collagen as a carrier for bone morphogenetic protein J Orthop Res 9 6 1991 902 907
    • (1991) J Orthop Res , vol.9 , Issue.6 , pp. 902-907
    • Takaoka, K.1    Koezuka, M.2    Nakahara, H.3
  • 64
    • 0034134364 scopus 로고    scopus 로고
    • Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites
    • Y. Okubo Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites Int J Oral Maxillofac Surg 29 1 2000 62 66
    • (2000) Int J Oral Maxillofac Surg , vol.29 , Issue.1 , pp. 62-66
    • Okubo, Y.1
  • 65
    • 79956095821 scopus 로고    scopus 로고
    • Effects of protein dose and delivery system on BMP-mediated bone regeneration
    • J.D. Boerckel Effects of protein dose and delivery system on BMP-mediated bone regeneration Biomaterials 32 22 2011 5241 5251
    • (2011) Biomaterials , vol.32 , Issue.22 , pp. 5241-5251
    • Boerckel, J.D.1
  • 66
    • 37849048694 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate
    • R.E. Jung, F.E. Weber, D.S. Thoma, M. Ehrbar, D.L. Cochran, and C.H. Hammerle Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate Clin Oral Implants Res 19 2 2008 188 195
    • (2008) Clin Oral Implants Res , vol.19 , Issue.2 , pp. 188-195
    • Jung, R.E.1    Weber, F.E.2    Thoma, D.S.3    Ehrbar, M.4    Cochran, D.L.5    Hammerle, C.H.6
  • 67
    • 77951770613 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 delivered by hyaluronan-based hydrogel induces massive bone formation and healing of cranial defects in minipigs
    • A.C. Docherty-Skogh Bone morphogenetic protein-2 delivered by hyaluronan-based hydrogel induces massive bone formation and healing of cranial defects in minipigs Plast Reconstr Surg 125 5 2010 1383 1392
    • (2010) Plast Reconstr Surg , vol.125 , Issue.5 , pp. 1383-1392
    • Docherty-Skogh, A.C.1
  • 68
    • 84855397191 scopus 로고    scopus 로고
    • Enhanced healing of rat calvarial defects with sulfated chitosan-coated calcium-deficient hydroxyapatite/bone morphogenetic protein 2 scaffolds
    • J. Zhao Enhanced healing of rat calvarial defects with sulfated chitosan-coated calcium-deficient hydroxyapatite/bone morphogenetic protein 2 scaffolds Tissue Eng A 18 1-2 2012 185 197
    • (2012) Tissue Eng A , vol.18 , Issue.12 , pp. 185-197
    • Zhao, J.1
  • 69
    • 21244483142 scopus 로고    scopus 로고
    • Insulin-like growth factor I-releasing alginate-tricalciumphosphate composites for bone regeneration
    • DOI 10.1007/s11095-005-4589-9
    • V. Luginbuehl, E. Wenk, A. Koch, B. Gander, H.P. Merkle, and L. Meinel Insulin-like growth factor I-releasing alginate-tricalciumphosphate composites for bone regeneration Pharm Res 22 6 2005 940 950 (Pubitemid 40898104)
    • (2005) Pharmaceutical Research , vol.22 , Issue.6 , pp. 940-950
    • Luginbuehl, V.1    Wenk, E.2    Koch, A.3    Gander, B.4    Merkle, H.P.5    Meinel, L.6
  • 70
    • 84863099299 scopus 로고    scopus 로고
    • In vivo osteoinductivity of gelatin beta-tri-calcium phosphate sponge and bone morphogenetic protein-2 on an equine third metacarpal bone defect
    • N. Tsuzuki In vivo osteoinductivity of gelatin beta-tri-calcium phosphate sponge and bone morphogenetic protein-2 on an equine third metacarpal bone defect Res Vet Sci 93 2 2012 1021 1025
    • (2012) Res Vet Sci , vol.93 , Issue.2 , pp. 1021-1025
    • Tsuzuki, N.1
  • 71
    • 84855930190 scopus 로고    scopus 로고
    • Analysis of hydrolyzable polyethylene glycol hydrogels and deproteinized bone mineral as delivery systems for glycosylated and non-glycosylated bone morphogenetic protein-2
    • P. Hänseler Analysis of hydrolyzable polyethylene glycol hydrogels and deproteinized bone mineral as delivery systems for glycosylated and non-glycosylated bone morphogenetic protein-2 Acta Biomater 8 1 2012 116 123
    • (2012) Acta Biomater , vol.8 , Issue.1 , pp. 116-123
    • Hänseler, P.1
  • 72
    • 78649552759 scopus 로고    scopus 로고
    • Injectable rhBMP-2-loaded chitosan hydrogel composite: Osteoinduction at ectopic site and in segmental long bone defect
    • L. Luca Injectable rhBMP-2-loaded chitosan hydrogel composite: osteoinduction at ectopic site and in segmental long bone defect J Biomed Mater Res A 96 1 2011 66 74
    • (2011) J Biomed Mater Res A , vol.96 , Issue.1 , pp. 66-74
    • Luca, L.1
  • 73
    • 84868503337 scopus 로고    scopus 로고
    • Minimally invasive mandibular bone augmentation using injectable hydrogels
    • E. Martínez -Sanz Minimally invasive mandibular bone augmentation using injectable hydrogels J Tissue Eng Regen Med 2012
    • (2012) J Tissue Eng Regen Med
    • Martínez -Sanz, E.1
  • 74
    • 84865808757 scopus 로고    scopus 로고
    • Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation
    • M. Kisiel Critical assessment of rhBMP-2 mediated bone induction: an in vitro and in vivo evaluation J Control Release 162 3 2012 646 653
    • (2012) J Control Release , vol.162 , Issue.3 , pp. 646-653
    • Kisiel, M.1
  • 75
    • 84891727740 scopus 로고    scopus 로고
    • Alveolar bone healing accompanied by severe swelling in cleft children treated with bone morphogenetic protein-2 delivered by hydrogel
    • E. Neovius, M. Lemberger, S.A. Docherty, J. Hilborn, and T. Engstrand Alveolar bone healing accompanied by severe swelling in cleft children treated with bone morphogenetic protein-2 delivered by hydrogel J Plast Reconstr Aesthet Surg 2012
    • (2012) J Plast Reconstr Aesthet Surg
    • Neovius, E.1    Lemberger, M.2    Docherty, S.A.3    Hilborn, J.4    Engstrand, T.5
  • 76
    • 84866870137 scopus 로고    scopus 로고
    • Nano-hydroxyapatite/fibrin glue/recombinant human osteogenic protein-1 artificial bone for repair of bone defect in an animal model
    • Z. Weimin Nano-hydroxyapatite/fibrin glue/recombinant human osteogenic protein-1 artificial bone for repair of bone defect in an animal model Micro & Nano Letters IET 7 5 2012 467 471
    • (2012) Micro & Nano Letters IET , vol.7 , Issue.5 , pp. 467-471
    • Weimin, Z.1
  • 77
    • 77957882710 scopus 로고    scopus 로고
    • Mineralization, biodegradation, and drug release behavior of gelatin/apatite composite microspheres for bone regeneration
    • S.C. Leeuwenburgh, J. Jo, H. Wang, M. Yamamoto, J.A. Jansen, and Y. Tabata Mineralization, biodegradation, and drug release behavior of gelatin/apatite composite microspheres for bone regeneration Biomacromolecules 11 10 2010 2653 2659
    • (2010) Biomacromolecules , vol.11 , Issue.10 , pp. 2653-2659
    • Leeuwenburgh, S.C.1    Jo, J.2    Wang, H.3    Yamamoto, M.4    Jansen, J.A.5    Tabata, Y.6
  • 79
    • 80051735442 scopus 로고    scopus 로고
    • Effect of enamel matrix derivative and parathyroid hormone on bone formation in standardized osseous defects: An experimental study in minipigs
    • S.S. Jensen, B. Chen, M.M. Bornstein, D.D. Bosshardt, and D. Buser Effect of enamel matrix derivative and parathyroid hormone on bone formation in standardized osseous defects: an experimental study in minipigs J Periodontol 82 8 2011 1197 1205
    • (2011) J Periodontol , vol.82 , Issue.8 , pp. 1197-1205
    • Jensen, S.S.1    Chen, B.2    Bornstein, M.M.3    Bosshardt, D.D.4    Buser, D.5
  • 80
    • 70349456493 scopus 로고    scopus 로고
    • In vitro growth factor release from injectable calcium phosphate cements containing gelatin microspheres
    • W.J. Habraken, O.C. Boerman, J.G. Wolke, A.G. Mikos, and J.A. Jansen In vitro growth factor release from injectable calcium phosphate cements containing gelatin microspheres J Biomed Mater Res A 91 2 2009 614 622
    • (2009) J Biomed Mater Res A , vol.91 , Issue.2 , pp. 614-622
    • Habraken, W.J.1    Boerman, O.C.2    Wolke, J.G.3    Mikos, A.G.4    Jansen, J.A.5
  • 81
    • 0033021062 scopus 로고    scopus 로고
    • Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration
    • DOI 10.1038/10473
    • J. Bonadio, E. Smiley, P. Patil, and S. Goldstein Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration Nat Med 5 7 1999 753 759 (Pubitemid 29318608)
    • (1999) Nature Medicine , vol.5 , Issue.7 , pp. 753-759
    • Bonadio, J.1    Smiley, E.2    Patil, P.3    Goldstein, S.4
  • 82
    • 75749150159 scopus 로고    scopus 로고
    • Calcium phosphate-DNA nanoparticle gene delivery from alginate hydrogels induces in vivo osteogenesis
    • M.D. Krebs, E. Salter, E. Chen, K.A. Sutter, and E. Alsberg Calcium phosphate-DNA nanoparticle gene delivery from alginate hydrogels induces in vivo osteogenesis J Biomed Mater Res A 92 3 2010 1131 1138
    • (2010) J Biomed Mater Res A , vol.92 , Issue.3 , pp. 1131-1138
    • Krebs, M.D.1    Salter, E.2    Chen, E.3    Sutter, K.A.4    Alsberg, E.5
  • 83
    • 61549132911 scopus 로고    scopus 로고
    • Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration
    • D.H.R. Kempen Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration Biomaterials 30 14 2009 2816 2825
    • (2009) Biomaterials , vol.30 , Issue.14 , pp. 2816-2825
    • Kempen, D.H.R.1
  • 84
    • 78649861129 scopus 로고    scopus 로고
    • Growth factor interactions in bone regeneration
    • D.H. Kempen Growth factor interactions in bone regeneration Tissue Eng B Rev 16 6 2010 551 566
    • (2010) Tissue Eng B Rev , vol.16 , Issue.6 , pp. 551-566
    • Kempen, D.H.1
  • 85
    • 70350503224 scopus 로고    scopus 로고
    • A bone-like nano-hydroxyapatite/collagen loaded injectable scaffold
    • Z. Huang, J. Tian, B. Yu, Y. Xu, and Q. Feng A bone-like nano-hydroxyapatite/collagen loaded injectable scaffold Biomed Mater 4 2009 1 7
    • (2009) Biomed Mater , vol.4 , pp. 1-7
    • Huang, Z.1    Tian, J.2    Yu, B.3    Xu, Y.4    Feng, Q.5
  • 86
    • 84861609403 scopus 로고    scopus 로고
    • Acidic peptide hydrogel scaffolds enhance calcium phosphate mineral turnover into bone tissue
    • N. Amosi Acidic peptide hydrogel scaffolds enhance calcium phosphate mineral turnover into bone tissue Acta Biomater 8 7 2012 2466 2475
    • (2012) Acta Biomater , vol.8 , Issue.7 , pp. 2466-2475
    • Amosi, N.1
  • 87
    • 84857953503 scopus 로고    scopus 로고
    • Biomimetic modification of synthetic hydrogels by incorporation of adhesive peptides and calcium phosphate nanoparticles: In vitro evaluation of cell behavior
    • M. Bongio Biomimetic modification of synthetic hydrogels by incorporation of adhesive peptides and calcium phosphate nanoparticles: in vitro evaluation of cell behavior Eur Cell Mater 22 2011 359 376
    • (2011) Eur Cell Mater , vol.22 , pp. 359-376
    • Bongio, M.1
  • 88
    • 84862290936 scopus 로고    scopus 로고
    • In vitro biocompatibility and osteoblast differentiation of an injectable chitosan/nano-hydroxyapatite/collagen scaffold
    • Article ID 401084 [6 pages]
    • Chen Y, Huang Z, Li X, et al., In vitro biocompatibility and osteoblast differentiation of an injectable chitosan/nano-hydroxyapatite/collagen scaffold. J Nanomaterials 2012;2012:Article ID 401084 [6 pages].
    • (2012) J Nanomaterials 2012
    • Chen, Y.1    Huang, Z.2    Li, X.3
  • 89
    • 84857809940 scopus 로고    scopus 로고
    • A hydrogel-mineral composite scaffold for osteochondral interface tissue engineering
    • N.T. Khanarian, J. Jiang, L.Q. Wan, V.C. Mow, and H.H. Lu A hydrogel-mineral composite scaffold for osteochondral interface tissue engineering Tissue Eng A 18 5-6 2012 533 545
    • (2012) Tissue Eng A , vol.18 , Issue.5-6 , pp. 533-545
    • Khanarian, N.T.1    Jiang, J.2    Wan, L.Q.3    Mow, V.C.4    Lu, H.H.5
  • 90
    • 33747152561 scopus 로고    scopus 로고
    • Matrix Elasticity Directs Stem Cell Lineage Specification
    • DOI 10.1016/j.cell.2006.06.044, PII S0092867406009615
    • A.J. Engler, S. Sen, H.L. Sweeney, and D.E. Discher Matrix elasticity directs stem cell lineage specification Cell 126 4 2006 677 689 (Pubitemid 44233625)
    • (2006) Cell , vol.126 , Issue.4 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 91
    • 67649920749 scopus 로고    scopus 로고
    • Growth factors, matrices, and forces combine and control stem cells
    • D.E. Discher, D.J. Mooney, and P.W. Zandstra Growth factors, matrices, and forces combine and control stem cells Science 324 5935 2009 1673 1677
    • (2009) Science , vol.324 , Issue.5935 , pp. 1673-1677
    • Discher, D.E.1    Mooney, D.J.2    Zandstra, P.W.3
  • 92
    • 21844438003 scopus 로고    scopus 로고
    • Porous scaffold design for tissue engineering
    • DOI 10.1038/nmat1421
    • S.J. Hollister Porous scaffold design for tissue engineering Nat Mater 4 7 2005 518 524 (Pubitemid 40952745)
    • (2005) Nature Materials , vol.4 , Issue.7 , pp. 518-524
    • Hollister, S.J.1
  • 93
    • 9344240796 scopus 로고    scopus 로고
    • Adhesion and growth of bone marrow stromal cells on modified alginate hydrogels
    • DOI 10.1089/ten.2004.10.1480
    • M.A. Lawson, J.E. Barralet, L. Wang, R.M. Shelton, and J.T. Triffitt Adhesion and growth of bone marrow stromal cells on modified alginate hydrogels Tissue Eng 10 9-10 2004 1480 1491 (Pubitemid 39557851)
    • (2004) Tissue Engineering , vol.10 , Issue.9-10 , pp. 1480-1491
    • Lawson, M.A.1    Barralet, J.E.2    Wang, L.3    Shelton, R.M.4    Triffitt, J.T.5
  • 94
    • 19644367664 scopus 로고    scopus 로고
    • Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
    • DOI 10.1038/nbt1055
    • M.P. Lutolf, and J.A. Hubbell Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering Nat Biotechnol 23 1 2005 47 55 (Pubitemid 41724624)
    • (2005) Nature Biotechnology , vol.23 , Issue.1 , pp. 47-55
    • Lutolf, M.P.1    Hubbell, J.A.2
  • 95
    • 78149264794 scopus 로고    scopus 로고
    • Yielding behavior in injectable hydrogels from telechelic proteins
    • B.D. Olsen, J.A. Kornfield, and D.A. Tirrell Yielding behavior in injectable hydrogels from telechelic proteins Macromolecules 43 21 2010 9094 9099
    • (2010) Macromolecules , vol.43 , Issue.21 , pp. 9094-9099
    • Olsen, B.D.1    Kornfield, J.A.2    Tirrell, D.A.3
  • 96
    • 78651432834 scopus 로고    scopus 로고
    • Multi-responsive hydrogels based on N-isopropylacrylamide and sodium alginate
    • R.P. Dumitriu, G.R. Mitchell, and C. Vasile Multi-responsive hydrogels based on N-isopropylacrylamide and sodium alginate Polym Int 60 2 2011 222 233
    • (2011) Polym Int , vol.60 , Issue.2 , pp. 222-233
    • Dumitriu, R.P.1    Mitchell, G.R.2    Vasile, C.3
  • 97
    • 84865627287 scopus 로고    scopus 로고
    • Single step synthesis and characterization of thermoresponsive hyaluronan hydrogels
    • M. D'Este, M. Alini, and D. Eglin Single step synthesis and characterization of thermoresponsive hyaluronan hydrogels Carbohydr Polym 90 3 2012 1378 1385
    • (2012) Carbohydr Polym , vol.90 , Issue.3 , pp. 1378-1385
    • D'Este, M.1    Alini, M.2    Eglin, D.3
  • 98
    • 84863170166 scopus 로고    scopus 로고
    • Biomimetic interpenetrating polymer network hydrogels based on methacrylated alginate and collagen for 3D pre-osteoblast spreading and osteogenic differentiation
    • J. Sun, W. Xiao, Y. Tang, K. Li, and H. Fan Biomimetic interpenetrating polymer network hydrogels based on methacrylated alginate and collagen for 3D pre-osteoblast spreading and osteogenic differentiation Soft Matter 8 8 2012 2398 2404
    • (2012) Soft Matter , vol.8 , Issue.8 , pp. 2398-2404
    • Sun, J.1    Xiao, W.2    Tang, Y.3    Li, K.4    Fan, H.5
  • 100
    • 65149091319 scopus 로고    scopus 로고
    • Biologically inspired rosette nanotubes and nanocrystalline hydroxyapatite hydrogel nanocomposites as improved bone substitutes
    • L. Zhang, J. Rodriguez, J. Raez, and A.J. Myles Biologically inspired rosette nanotubes and nanocrystalline hydroxyapatite hydrogel nanocomposites as improved bone substitutes Nanotechnology 20 17 2009 175101
    • (2009) Nanotechnology , vol.20 , Issue.17 , pp. 175101
    • Zhang, L.1    Rodriguez, J.2    Raez, J.3    Myles, A.J.4
  • 101
    • 84857785822 scopus 로고    scopus 로고
    • Incorporation of phosphate group modulates bone cell attachment and differentiation on oligo(polyethylene glycol) fumarate hydrogel
    • M. Dadsetan, M. Giuliani, F. Wanivenhaus, M. Brett Runge, J.E. Charlesworth, and M.J. Yaszemski Incorporation of phosphate group modulates bone cell attachment and differentiation on oligo(polyethylene glycol) fumarate hydrogel Acta Biomater 8 4 2012 1430 1439
    • (2012) Acta Biomater , vol.8 , Issue.4 , pp. 1430-1439
    • Dadsetan, M.1    Giuliani, M.2    Wanivenhaus, F.3    Brett Runge, M.4    Charlesworth, J.E.5    Yaszemski, M.J.6
  • 102
    • 84861593355 scopus 로고    scopus 로고
    • In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers
    • N. Davison, H. Yuan, J.D. de Bruijn, and G.F. Barrere-de In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers Acta Biomater 8 7 2012 2759 2769
    • (2012) Acta Biomater , vol.8 , Issue.7 , pp. 2759-2769
    • Davison, N.1    Yuan, H.2    De Bruijn, J.D.3    Barrere-De, G.F.4
  • 103
    • 80054083256 scopus 로고    scopus 로고
    • Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation
    • T. Manaka, A. Suzuki, K. Takayama, Y. Imai, H. Nakamura, and K. Takaoka Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation Biomaterials 32 36 2011 9642 9648
    • (2011) Biomaterials , vol.32 , Issue.36 , pp. 9642-9648
    • Manaka, T.1    Suzuki, A.2    Takayama, K.3    Imai, Y.4    Nakamura, H.5    Takaoka, K.6
  • 105
    • 77953809370 scopus 로고    scopus 로고
    • Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix
    • A. Mata Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix Biomaterials 31 23 2010 6004 6012
    • (2010) Biomaterials , vol.31 , Issue.23 , pp. 6004-6012
    • Mata, A.1
  • 106
    • 78249279058 scopus 로고    scopus 로고
    • In vivo evaluation of MMP sensitive high-molecular weight HA-based hydrogels for bone tissue engineering
    • J. Kim In vivo evaluation of MMP sensitive high-molecular weight HA-based hydrogels for bone tissue engineering J Biomed Mater Res A 95 3 2010 673 681
    • (2010) J Biomed Mater Res A , vol.95 , Issue.3 , pp. 673-681
    • Kim, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.