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Volumn 31, Issue 1, 2013, Pages 152-159

Phase II study of irinotecan plus capecitabine in anthracycline-and taxane-pretreated patients with metastatic breast cancer

Author keywords

Capecitabine; Chemotherapy; Irinotecan; Metastatic breast cancer

Indexed keywords

ANTHRACYCLINE; BICARBONATE; CAPECITABINE; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FLUOROURACIL; GEMCITABINE; IRINOTECAN; MAGNESIUM OXIDE; NAVELBINE; PACLITAXEL; PROGESTERONE RECEPTOR; SEROTONIN 3 ANTAGONIST; TAXANE DERIVATIVE; TRASTUZUMAB; URSODEOXYCHOLIC ACID;

EID: 84873088845     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-012-9824-8     Document Type: Article
Times cited : (13)

References (28)
  • 1
    • 67650874081 scopus 로고    scopus 로고
    • Cancer statistics, 2009
    • 10.3322/caac.20006 19474385 10.3322/caac.20006
    • Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ (2009) Cancer statistics, 2009. CA Cancer J Clin 59(4):225-249. doi: 10.3322/caac.20006
    • (2009) CA Cancer J Clin , vol.59 , Issue.4 , pp. 225-249
    • Jemal, A.1    Siegel, R.2    Ward, E.3    Hao, Y.4    Xu, J.5    Thun, M.J.6
  • 3
    • 16844373011 scopus 로고    scopus 로고
    • Optimizing the treatment of metastatic breast cancer
    • 10.1007/s10549-005-0143-z 15770536 10.1007/s10549-005-0143-z 1:CAS:528:DC%2BD2MXkt1Cjsbk%3D
    • Gralow JR (2005) Optimizing the treatment of metastatic breast cancer. Breast Cancer Res Treat 89(Suppl 1):S9-S15. doi: 10.1007/s10549-005-0143-z
    • (2005) Breast Cancer Res Treat , vol.89 , Issue.SUPPL. 1
    • Gralow, J.R.1
  • 4
    • 77951039968 scopus 로고    scopus 로고
    • Management of metastatic breast cancer: Monotherapy options for patients resistant to anthracyclines and taxanes
    • 10.1097/COC.0b013e3181931049 19675449 1:CAS:528:DC%2BC3cXksFSitLk%3D
    • Rivera E (2010) Management of metastatic breast cancer: monotherapy options for patients resistant to anthracyclines and taxanes. Am J Clin Oncol 33(2):176-185. doi: 10.1097/COC.0b013e3181931049
    • (2010) Am J Clin Oncol , vol.33 , Issue.2 , pp. 176-185
    • Rivera, E.1
  • 5
    • 0032127244 scopus 로고    scopus 로고
    • Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
    • 9849491 10.1016/S0959-8049(98)00058-6 1:CAS:528:DyaK1cXltlCgsrk%3D
    • Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, Shimma N, Umeda I, Ishitsuka H (1998) Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 34(8):1274-1281
    • (1998) Eur J Cancer , vol.34 , Issue.8 , pp. 1274-1281
    • Miwa, M.1    Ura, M.2    Nishida, M.3    Sawada, N.4    Ishikawa, T.5    Mori, K.6    Shimma, N.7    Umeda, I.8    Ishitsuka, H.9
  • 6
    • 0034016415 scopus 로고    scopus 로고
    • Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients
    • 10.1007/s002800050043 10755317 10.1007/s002800050043 1:CAS:528: DC%2BD3cXhtlCrtLk%3D
    • Schuller J, Cassidy J, Dumont E, Roos B, Durston S, Banken L, Utoh M, Mori K, Weidekamm E, Reigner B (2000) Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients. Cancer Chemother Pharmacol 45(4):291-297. doi: 10.1007/s002800050043
    • (2000) Cancer Chemother Pharmacol , vol.45 , Issue.4 , pp. 291-297
    • Schuller, J.1    Cassidy, J.2    Dumont, E.3    Roos, B.4    Durston, S.5    Banken, L.6    Utoh, M.7    Mori, K.8    Weidekamm, E.9    Reigner, B.10
  • 7
    • 37049007420 scopus 로고    scopus 로고
    • An open-label, multicenter study of outpatient capecitabine monotherapy in 631 patients with pretreated advanced breast cancer
    • 10.1159/000111094 18004077 10.1159/000111094 1:STN:280: DC%2BD2sjitVymsg%3D%3D
    • Venturini M, Paridaens R, Rossner D, Vaslamatzis MM, Nortier JW, Salzberg M, Rodrigues H, Bell R (2007) An open-label, multicenter study of outpatient capecitabine monotherapy in 631 patients with pretreated advanced breast cancer. Oncology 72(1-2):51-57. doi: 10.1159/000111094
    • (2007) Oncology , vol.72 , Issue.1-2 , pp. 51-57
    • Venturini, M.1    Paridaens, R.2    Rossner, D.3    Vaslamatzis, M.M.4    Nortier, J.W.5    Salzberg, M.6    Rodrigues, H.7    Bell, R.8
  • 8
    • 1842627763 scopus 로고    scopus 로고
    • Oral capecitabine in anthracycline- and taxane-pretreated advanced/metastatic breast cancer
    • 10.1080/02841860310023165 15163168 10.1080/02841860310023165
    • Wist EA, Sommer HH, Ostenstad B, Risberg T, Bremnes Y, Mjaaland I (2004) Oral capecitabine in anthracycline- and taxane-pretreated advanced/metastatic breast cancer. Acta Oncol 43(2):186-189. doi: 10.1080/02841860310023165
    • (2004) Acta Oncol , vol.43 , Issue.2 , pp. 186-189
    • Wist, E.A.1    Sommer, H.H.2    Ostenstad, B.3    Risberg, T.4    Bremnes, Y.5    Mjaaland, I.6
  • 9
    • 0041508753 scopus 로고    scopus 로고
    • Multicenter phase II study of oral capecitabine (Xeloda(″)) in patients with metastatic breast cancer relapsing after treatment with a taxane-containing therapy
    • 10.1093/annonc/mdg346 12881384 10.1093/annonc/mdg346 1:STN:280: DC%2BD3szkvVaruw%3D%3D
    • Reichardt P, Von Minckwitz G, Thuss-Patience PC, Jonat W, Kolbl H, Janicke F, Kieback DG, Kuhn W, Schindler AE, Mohrmann S (2003) Multicenter phase II study of oral capecitabine (Xeloda(″)) in patients with metastatic breast cancer relapsing after treatment with a taxane-containing therapy. Ann Oncol 14(8):1227-1233. doi: 10.1093/annonc/mdg346
    • (2003) Ann Oncol , vol.14 , Issue.8 , pp. 1227-1233
    • Reichardt, P.1    Von Minckwitz, G.2    Thuss-Patience, P.C.3    Jonat, W.4    Kolbl, H.5    Janicke, F.6    Kieback, D.G.7    Kuhn, W.8    Schindler, A.E.9    Mohrmann, S.10
  • 10
    • 10744229320 scopus 로고    scopus 로고
    • Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer
    • 10.1016/j.ejca.2003.11.007 14962720 10.1016/j.ejca.2003.11.007 1:CAS:528:DC%2BD2cXhtFWjsbc%3D
    • Fumoleau P, Largillier R, Clippe C, Dieras V, Orfeuvre H, Lesimple T, Culine S, Audhuy B, Serin D, Cure H (2004) Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer. Eur J Cancer 40(4):536-542. doi: 10.1016/j.ejca.2003.11.007
    • (2004) Eur J Cancer , vol.40 , Issue.4 , pp. 536-542
    • Fumoleau, P.1    Largillier, R.2    Clippe, C.3    Dieras, V.4    Orfeuvre, H.5    Lesimple, T.6    Culine, S.7    Audhuy, B.8    Serin, D.9    Cure, H.10
  • 11
    • 0030826929 scopus 로고    scopus 로고
    • Topoisomerase i inhibitors: Review and update
    • 9358934 10.1023/A:1008270717294 1:STN:280:DyaK1c%2Fitlyguw%3D%3D
    • Rothenberg ML (1997) Topoisomerase I inhibitors: review and update. Ann Oncol 8(9):837-855
    • (1997) Ann Oncol , vol.8 , Issue.9 , pp. 837-855
    • Rothenberg, M.L.1
  • 12
    • 4344695312 scopus 로고    scopus 로고
    • Randomized phase II study of two irinotecan schedules for patients with metastatic breast cancer refractory to an anthracycline, a taxane, or both
    • 10.1200/JCO.2004.10.047 15254052 10.1200/JCO.2004.10.047 1:CAS:528:DC%2BD2cXpsVWkt7c%3D
    • Perez EA, Hillman DW, Mailliard JA, Ingle JN, Ryan JM, Fitch TR, Rowland KM, Kardinal CG, Krook JE, Kugler JW (2004) Randomized phase II study of two irinotecan schedules for patients with metastatic breast cancer refractory to an anthracycline, a taxane, or both. J Clin Oncol 22(14):2849-2855. doi: 10.1200/JCO.2004.10.047
    • (2004) J Clin Oncol , vol.22 , Issue.14 , pp. 2849-2855
    • Perez, E.A.1    Hillman, D.W.2    Mailliard, J.A.3    Ingle, J.N.4    Ryan, J.M.5    Fitch, T.R.6    Rowland, K.M.7    Kardinal, C.G.8    Krook, J.E.9    Kugler, J.W.10
  • 13
    • 0034798071 scopus 로고    scopus 로고
    • Clinical effect of irinotecan in advanced and metastatic breast cancer patients previously treated with doxorubicin- and docetaxel-containing regimens
    • 10.1093/jjco/hye082 11574629 10.1093/jjco/hye082 1:STN:280: DC%2BD3MrivVGitQ%3D%3D
    • Shigeoka Y, Itoh K, Igarashi T, Ishizawa K, Saeki T, Fujii H, Minami H, Imoto S, Sasaki Y (2001) Clinical effect of irinotecan in advanced and metastatic breast cancer patients previously treated with doxorubicin- and docetaxel-containing regimens. Jpn J Clin Oncol 31(8):370-374. doi: 10.1093/jjco/hye082
    • (2001) Jpn J Clin Oncol , vol.31 , Issue.8 , pp. 370-374
    • Shigeoka, Y.1    Itoh, K.2    Igarashi, T.3    Ishizawa, K.4    Saeki, T.5    Fujii, H.6    Minami, H.7    Imoto, S.8    Sasaki, Y.9
  • 14
    • 34848869099 scopus 로고    scopus 로고
    • A phase i study of capecitabine and a modulatory dose of irinotecan in metastatic breast cancer
    • 10.1007/s00280-007-0456-1 17426973 10.1007/s00280-007-0456-1
    • O'Connor T, Rustum Y, Levine E, Creaven P (2008) A phase I study of capecitabine and a modulatory dose of irinotecan in metastatic breast cancer. Cancer Chemother Pharmacol 61(1):125-131. doi: 10.1007/s00280-007-0456-1
    • (2008) Cancer Chemother Pharmacol , vol.61 , Issue.1 , pp. 125-131
    • O'Connor, T.1    Rustum, Y.2    Levine, E.3    Creaven, P.4
  • 16
    • 6944226476 scopus 로고    scopus 로고
    • Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer
    • 10.1038/sj.bjc.6602139 15354215 10.1038/sj.bjc.6602139 1:CAS:528:DC%2BD2cXnvFCgtbs%3D
    • Ichikawa W, Takahashi T, Suto K, Yamashita T, Nihei Z, Shirota Y, Shimizu M, Sasaki Y, Hirayama R (2004) Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer. Br J Cancer 91(7):1245-1250. doi: 10.1038/sj.bjc.6602139
    • (2004) Br J Cancer , vol.91 , Issue.7 , pp. 1245-1250
    • Ichikawa, W.1    Takahashi, T.2    Suto, K.3    Yamashita, T.4    Nihei, Z.5    Shirota, Y.6    Shimizu, M.7    Sasaki, Y.8    Hirayama, R.9
  • 17
    • 29144494850 scopus 로고    scopus 로고
    • Phase II study of weekly irinotecan plus capecitabine for chemotherapy-naive patients with advanced nonsmall cell lung carcinoma
    • 10.1002/cncr.21563 16294344 10.1002/cncr.21563 1:CAS:528: DC%2BD28XptlSkug%3D%3D
    • Han JY, Lee DH, Lee SY, Park CG, Kim HY, Lee HG, Lee JJ, Kim HT, Lee JS (2005) Phase II study of weekly irinotecan plus capecitabine for chemotherapy-naive patients with advanced nonsmall cell lung carcinoma. Cancer 104(12):2759-2765. doi: 10.1002/cncr.21563
    • (2005) Cancer , vol.104 , Issue.12 , pp. 2759-2765
    • Han, J.Y.1    Lee, D.H.2    Lee, S.Y.3    Park, C.G.4    Kim, H.Y.5    Lee, H.G.6    Lee, J.J.7    Kim, H.T.8    Lee, J.S.9
  • 18
    • 3242881591 scopus 로고    scopus 로고
    • Cancer Therapy Evaluation Program. Bethestha, MD, National Cancer Institute doi: 10.1016/S1053-4296(03)00031-6
    • CTEP: Common Terminology Criteria for Adverse Events v3.0 (CTCAE), Cancer Therapy Evaluation Program. Bethestha, MD, National Cancer Institute. 2003. doi: 10.1016/S1053-4296(03)00031-6
    • (2003) CTEP: Common Terminology Criteria for Adverse Events v3.0 (CTCAE)
  • 19
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • 10.1093/jnci/92.3.205 10655437 10.1093/jnci/92.3.205 1:STN:280: DC%2BD3c7it1Gitg%3D%3D
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Van Glabbeke M, van Oosterom AT, Christian MC (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92(3):205-216. doi: 10.1093/jnci/92.3.205
    • (2000) J Natl Cancer Inst , vol.92 , Issue.3 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6    Verweij, J.7    Van Glabbeke, M.8    Van Oosterom, A.T.9    Christian, M.C.10
  • 20
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • 2702835 10.1016/0197-2456(89)90015-9 1:STN:280:DyaL1M7ps1SjsQ%3D%3D
    • Simon R (1989) Optimal two-stage designs for phase II clinical trials. Control Clin Trials 10(1):1-10
    • (1989) Control Clin Trials , vol.10 , Issue.1 , pp. 1-10
    • Simon, R.1
  • 21
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • 10.1080/01621459.1958.10501452
    • Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 22
    • 36849071808 scopus 로고    scopus 로고
    • Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
    • 10.1200/JCO.2007.12.6557 17968020 10.1200/JCO.2007.12.6557 1:CAS:528:DC%2BD2sXhsVKnsbzO
    • Thomas ES, Gomez HL, Li RK, Chung HC, Fein LE, Chan VF, Jassem J, Pivot XB, Klimovsky JV, de Mendoza FH (2007) Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J Clin Oncol 25(33):5210-5217. doi: 10.1200/JCO.2007.12.6557
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5210-5217
    • Thomas, E.S.1    Gomez, H.L.2    Li, R.K.3    Chung, H.C.4    Fein, L.E.5    Chan, V.F.6    Jassem, J.7    Pivot, X.B.8    Klimovsky, J.V.9    De Mendoza, F.H.10
  • 23
    • 2342459714 scopus 로고    scopus 로고
    • Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
    • 15007088 10.1200/JCO.2004.07.173 1:CAS:528:DC%2BD2cXpt1yjtbk%3D
    • Innocenti F, Undevia SD, Iyer L, Chen PX, Das S, Kocherginsky M, Karrison T, Janisch L, Ramirez J, Rudin CM (2004) Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 22(8):1382-1388
    • (2004) J Clin Oncol , vol.22 , Issue.8 , pp. 1382-1388
    • Innocenti, F.1    Undevia, S.D.2    Iyer, L.3    Chen, P.X.4    Das, S.5    Kocherginsky, M.6    Karrison, T.7    Janisch, L.8    Ramirez, J.9    Rudin, C.M.10
  • 24
    • 33744804311 scopus 로고    scopus 로고
    • Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin
    • 10.1200/JCO.2004.07.173 16636344 10.1200/JCO.2005.03.0239 1:CAS:528:DC%2BD28XlvV2ksLg%3D
    • Han JY, Lim HS, Shin ES, Yoo YK, Park YH, Lee JE, Jang IJ, Lee DH, Lee JS (2006) Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin. J Clin Oncol 24(15):2237-2244. doi: 10.1200/JCO.2004.07.173
    • (2006) J Clin Oncol , vol.24 , Issue.15 , pp. 2237-2244
    • Han, J.Y.1    Lim, H.S.2    Shin, E.S.3    Yoo, Y.K.4    Park, Y.H.5    Lee, J.E.6    Jang, I.J.7    Lee, D.H.8    Lee, J.S.9
  • 25
    • 66349133649 scopus 로고    scopus 로고
    • Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan
    • 10.1200/JCO.2008.19.0314 19364970 10.1200/JCO.2008.19.0314 1:CAS:528:DC%2BD1MXmvVOhsL0%3D
    • Cecchin E, Innocenti F, D'Andrea M, Corona G, De Mattia E, Biason P, Buonadonna A, Toffoli G (2009) Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan. J Clin Oncol 27(15):2457-2465. doi: 10.1200/JCO.2008.19.0314
    • (2009) J Clin Oncol , vol.27 , Issue.15 , pp. 2457-2465
    • Cecchin, E.1    Innocenti, F.2    D'Andrea, M.3    Corona, G.4    De Mattia, E.5    Biason, P.6    Buonadonna, A.7    Toffoli, G.8
  • 26
    • 0031864410 scopus 로고    scopus 로고
    • Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II
    • 10.1016/S0925-4439(98)00013-1 9630669 10.1016/S0925-4439(98)00013-1 1:CAS:528:DyaK1cXjs1ahsLw%3D
    • Yamamoto K, Sato H, Fujiyama Y, Doida Y, Bamba T (1998) Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II. Biochim Biophys Acta 1406(3):267-273. doi: 10.1016/S0925-4439(98)00013- 1
    • (1998) Biochim Biophys Acta , vol.1406 , Issue.3 , pp. 267-273
    • Yamamoto, K.1    Sato, H.2    Fujiyama, Y.3    Doida, Y.4    Bamba, T.5
  • 27
    • 0035871991 scopus 로고    scopus 로고
    • Prevention of irinotecan (CPT-11)-induced diarrhea by oral alkalization combined with control of defecation in cancer patients
    • 10.1002/1097-0215(200102 11291056 10.1002/1097-0215(200102)9999:9999<: AID-IJC1179>3.0.CO;2-3 1:CAS:528:DC%2BD3MXivVKqtbc%3D
    • Takeda Y, Kobayashi K, Akiyama Y, Soma T, Handa S, Kudoh S, Kudo K (2001) Prevention of irinotecan (CPT-11)-induced diarrhea by oral alkalization combined with control of defecation in cancer patients. Int J Cancer 92(2):269-275. doi: 10.1002/1097-0215(200102
    • (2001) Int J Cancer , vol.92 , Issue.2 , pp. 269-275
    • Takeda, Y.1    Kobayashi, K.2    Akiyama, Y.3    Soma, T.4    Handa, S.5    Kudoh, S.6    Kudo, K.7
  • 28
    • 28544453597 scopus 로고    scopus 로고
    • A phase I/II trial of irinotecan-cisplatin combined with an anti-late-diarrhoeal programme to evaluate the safety and antitumour response of this combination therapy in patients with advanced non-small-cell lung cancer
    • 10.1038/sj.bjc.6602866 16288302 10.1038/sj.bjc.6602866 1:CAS:528:DC%2BD2MXht1yju7jF
    • Takeda Y, Tsuduki E, Izumi S, Hojo M, Kamimura M, Naka G, Kobayashi K, Kudo K (2005) A phase I/II trial of irinotecan-cisplatin combined with an anti-late-diarrhoeal programme to evaluate the safety and antitumour response of this combination therapy in patients with advanced non-small-cell lung cancer. Br J Cancer 93(12):1341-1349. doi: 10.1038/sj.bjc.6602866
    • (2005) Br J Cancer , vol.93 , Issue.12 , pp. 1341-1349
    • Takeda, Y.1    Tsuduki, E.2    Izumi, S.3    Hojo, M.4    Kamimura, M.5    Naka, G.6    Kobayashi, K.7    Kudo, K.8


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