Intestinal Ischemia

Textbook of Gastroenterology, Fifth Edition

Volumn 2, Issue , 2009, Pages 2811-2830

  Panés, Julián ^a,b   Piqué, Josep M ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

Author keywords

Acute mesenteric ischemia; Chronic mesenteric ischemia; Intestinal ischemia intestinal circulation anatomy; Ischemic colitis; Ischemic injury mechanisms; Mesenteric ischemia hypercoagulability states, thrombocytosis, polycythemia; Superior mesenteric artery (SMA); Unusual causes of mesenteric ischemia and obstructing diseases

Indexed keywords

EID: 84873086104     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444303254.ch113     Document Type: Chapter

References (148)

1. Stoney RJ, Cunningham CG. Acute mesenteric ischemia. Surgery 1993; 114: 489.
2. Brandt LJ, Boley SJ. AGA technical review on intestinal ischemia. American Gastrointestinal Association. Gastroenterology 2000; 118: 954.
3. Rosenblum JD, Boyle CM, Schwartz LB. The mesenteric circulation. Anatomy and physiology. Surg Clin North Am 1997; 77: 289.
4. Kornblith PL, Boley SJ, Whitehouse BS. Anatomy of the splanchnic circulation. Surg Clin North Am 1992; 72: 1.
5. Yamazaki T, Shirai Y, Tada T, et al. Ischemic colitis arising in watershed areas of the colonic blood supply: a report of two cases. Surg Today 1997; 27: 460.
6. Rhee RY, Gloviczki P. Mesenteric venous thrombosis. Surg Clin North Am 1997; 77: 327.
7. Fukatsu K, Sakamoto S, Hara E, et al. Gut ischemia-reperfusion affects gut mucosal immunity: a possible mechanism for infectious complications after severe surgical insults. Crit Care Med 2006; 34: 182.
8. Panés J, Granger DN. Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease. Gastroenterology 1998; 114: 1066.
9. Hayward R, Lefer AM. Time course of endothelial-neutrophil interaction in splanchnic artery ischemia-reperfusion. Am J Physiol 1998; 275: H2080.
10. Yadav SS, Howell DN, Gao W, et al. L-selectin and ICAM-1 mediate reperfusion injury and neutrophil adhesion in the warm ischemic mouse liver. Am J Physiol 1998; 275: G1341.
11. Andrews FJ, Malcontenti-Wilson C, O'Brien PE. Expression of adhesion molecules and leukocyte recruitment into gastric mucosa following ischemia-reperfusion. Dig Dis Sci 1997; 42: 326.
12. Meyer K, Brown MF, Zibari G, et al. ICAM-1 upregulation in distant tissues after hepatic ischemia/reperfusion: a clue to the mechanism of multiple organ failure. J Pediatr Surg 1998; 33: 350.
13. Kurose I, Anderson DC, Miyasaka M, et al. Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage. Circ Res 1994; 74: 336.
14. Tailor A, Granger DN. Hypercholesterolemia promotes leukocyte-dependent platelet adhesion in murine postcapillary venules. Microcirculation 2004; 11: 597.
15. Panés J, Kurose I, Rodriguez-Vaca MD, et al. Diabetes exacerbates the inflammatory responses to ischemia-reperfusion. Circulation 1996; 93: 161.
16. Salas A, Panés J, Elizalde JI, et al. Mechanisms responsible for enhanced inflammatory response to ischemia-reperfusion in diabetes. Am J Physiol 1998; 275: H1773.
17. Salas A, Panés J, Elizalde JI, et al. Reperfusion-induced oxidative stress in diabetes: cellular and enzymatic sources. J Leukoc Biol 1999; 66: 59.
18. Salas A, Panes J, Rosenbloom CL, et al. Differential effects of a nitric oxide donor on reperfusion-induced microvascular dysfunction in diabetic and non-diabetic rats. Diabetologia 1999; 42: 1350.
19. Granger DN. Ischemia-reperfusion: mechanisms of microvascular dysfunction and the influence of risk factors for cardiovascular disease. Microcirculation 1999; 6: 167.
20. Sola A, Panes J, Xaus C, et al. Fructose-1,6-biphosphate and nucleoside pool modifications prevent neutrophil accumulation in the reperfused intestine. J Leukoc Biol 2003; 73: 74.
21. Kubes P, Kurose I, Granger DN. NO donors prevent integrininduced leukocyte adhesion but not P-selectin-dependent rolling in postischemic venules. Am J Physiol 1994; 267: H931.
22. Barrachina MD, Panés J, Esplugues JV. Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases: perspective for drugs development. Curr Pharm Des 2001; 7: 31.
23. Cerwinka WH, Cooper D, Krieglstein CF, et al. Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules. Am J Physiol Heart Circ Physiol 2003; 284: H535.
24. Kozuch PL, Brandt LJ. Review article: diagnosis and management of mesenteric ischaemia with an emphasis on pharmacotherapy. Aliment Pharmacol Ther 2005; 21: 201.
25. Burns BJ, Brandt LJ. Intestinal ischemia. Gastroenterol Clin North Am 2003; 32: 1127.
26. McKinsey JF, Gewertz BL. Acute mesenteric ischemia. Surg Clin North Am 1997; 77: 307.
27. Hylek EM, Skates SJ, Sheehan MA, et al. An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation. N Engl J Med 1996; 335: 540.
28. Kaleya RN, Boley SJ. Acute mesenteric ischemia. Crit Care Clin 1995; 11: 479.
29. Acosta S, Ogren M, Sternby NH, et al. Clinical implications for the management of acute thromboembolic occlusion of the superior mesenteric artery: autopsy findings in 213 patients. Ann Surg 2005; 241: 516.
30. Reilly PM, Bulkley GB. Vasoactive mediators and splanchnic perfusion. Crit Care Med 1993; 21: S55.
31. Kim EH, Gewertz BL. Chronic digitalis administration alters mesenteric vascular reactivity. J Vasc Surg 1987; 5: 382.
32. John AS, Tuerff SD, Kerstein MD. Nonocclusive mesenteric infarction in hemodialysis patients. J Am Coll Surg 2000; 190: 84.
33. Gennaro M, Ascer E, Matano R, et al. Acute mesenteric ischemia after cardiopulmonary bypass. Am J Surg 1993; 166: 231.
34. Moriau M, Azerad MA. Importance of a medical treatment in mesenteric vein thrombosis (MVT). Acta Gastroenterol Belg 1996; 59: 146.
35. Rhee RY, Gloviczki P, Mendonca CT, et al. Mesenteric venous thrombosis: still a lethal disease in the 1990s. J Vasc Surg 1994; 20: 688.
36. Acosta S, Ogren M, Sternby NH, et al. Mesenteric venous thrombosis with transmural intestinal infarction: a population-based study. J Vasc Surg 2005; 41: 59.
37. Kumar S, Sarr MG, Kamath PS. Mesenteric venous thrombosis. N Engl J Med 2001; 345: 1683.
38. Cappell MS. Intestinal (mesenteric) vasculopathy. I. Acute superior mesenteric arteriopathy and venopathy. Gastroenterol Clin North Am 1998; 27: 783.
39. Eldrup-Jorgensen J, Hawkins RE, Bredenberg CE. Abdominal vascular catastrophes. Surg Clin North Am 1997; 77: 1305.
40. Kaleya RN, Sammartano RJ, Boley SJ. Aggressive approach to acute mesenteric ischemia. Surg Clin North Am 1992; 72: 157.
41. Reinus JF, Brandt LJ, Boley SJ. Ischemic diseases of the bowel. Gastroenterol Clin North Am 1990; 19: 319.
42. Tsai CJ, Kuo YC, Chen PC, et al. The spectrum of acute intestinal vascular failure: a collective review of 43 cases in Taiwan. Br J Clin Pract 1990; 44: 603.
43. Murray MJ, Gonze MD, Nowak LR, et al. Serum D-lactate levels as an aid to diagnosing acute intestinal ischemia. Am J Surg 1994; 167: 575.
44. Kanda T, Fujii H, Tani T, et al. Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans. Gastroenterology 1996; 110: 339.
45. Acosta S, Nilsson TK, Bjorck M. Preliminary study of D-dimer as a possible marker of acute bowel ischaemia. Br J Surg 2001; 88: 385.
46. Smerud MJ, Johnson CD, Stephens DH. Diagnosis of bowel infarction: a comparison of plain films and CT scans in 23 cases. AJR Am J Roentgenol 1990; 154: 99.
47. Klein HM, Lensing R, Klosterhalfen B, et al. Diagnostic imaging of mesenteric infarction. Radiology 1995; 197: 79.
48. Bowersox JC, Zwolak RM, Walsh DB, et al. Duplex ultrasonography in the diagnosis of celiac and mesenteric artery occlusive disease. J Vasc Surg 1991; 14: 780.
49. Kaufman SL, Harrington DP, Siegelman SS. Superior mesenteric artery embolization: an angiographic emergency. Radiology 1977; 124: 625.
50. Clark RA, Gallant TE. Acute mesenteric ischemia: angiographic spectrum. AJR Am J Roentgenol 1984; 142: 555.
51. Bakal CW, Sprayregen S, Wolf EL. Radiology in intestinal ischemia. Angiographic diagnosis and management. Surg Clin North Am 1992; 72: 125.
52. Sheedy SP, Earnest F, Fletcher JG, et al. CT of small-bowel ischemia associated with obstruction in emergency department patients: diagnostic performance evaluation. Radiology 2006; 241: 729.
53. Wiesner W, Hauser A, Steinbrich W. Accuracy of multidetector row computed tomography for the diagnosis of acute bowel ischemia in a non-selected study population. Eur Radiol 2004; 14: 2347.
54. Angelelli G, Scardapane A, Memeo M, et al. Acute bowel ischemia: CT findings. Eur J Radiol 2004; 50: 37.
55. Kirkpatrick ID, Kroeker MA, Greenberg HM. Biphasic CT with mesenteric CT angiography in the evaluation of acute mesenteric ischemia: initial experience. Radiology 2003; 229: 91.
56. Mallo RD, Salem L, Lalani T, et al. Computed tomography diagnosis of ischemia and complete obstruction in small bowel obstruction: a systematic review. J Gastrointest Surg 2005; 9: 690.
57. Gilfeather M, Holland GA, Siegelman ES, et al. Gadolinium-enhanced ultrafast three-dimensional spoiled gradient-echo MR imaging of the abdominal aorta and visceral and iliac vessels. Radiographics 1997; 17: 423.
58. Meaney JF, Prince MR, Nostrant TT, et al. Gadolinium-enhanced MR angiography of visceral arteries in patients with suspected chronic mesenteric ischemia. J Magn Reson Imaging 1997; 7: 171.
59. Kreft B, Strunk H, Flacke S, et al. Detection of thrombosis in the portal venous system: comparison of contrast-enhanced MR angiography with intraarterial digital subtraction angiography. Radiology 2000; 216: 86.
60. Burkart DJ, Johnson CD, Reading CC, et al. MR measurements of mesenteric venous flow: prospective evaluation in healthy volunteers and patients with suspected chronic mesenteric ischemia. Radiology 1995; 194: 801.
61. Li KC, Hopkins KL, Dalman RL, et al. Simultaneous measurement of flow in the superior mesenteric vein and artery with cine phase-contrast MR imaging: value in diagnosis of chronic mesenteric ischemia. Work in progress. Radiology 1995; 194: 327.
62. Ward D, Vernava AM, Kaminski DL, et al. Improved outcome by identification of high-risk nonocclusive mesenteric ischemia, aggressive reexploration, and delayed anastomosis. Am J Surg 1995; 170: 577.
63. Krummen DM, Cannova J, Schreiber H. Conservative management strategy for pancreatitis-associated mesenteric venous thrombosis. Am Surg 1996; 62: 432.
64. Gallego AM, Ramirez P, Rodriguez JM, et al. Role of urokinase in the superior mesenteric artery embolism. Surgery 1996; 120: 111.
65. Simo G, Echenagusia AJ, Camunez F, et al. Superior mesenteric arterial embolism: local fibrinolytic treatment with urokinase. Radiology 1997; 204: 775.
66. Lock G. Acute intestinal ischaemia. Best Pract Res Clin Gastroenterol 2001; 15: 83.
67. Grieshop RJ, Dalsing MC, Cikrit DF, et al. Acute mesenteric venous thrombosis. Revisited in a time of diagnostic clarity. Am Surg 1991; 57: 573.
68. Rundback JH. Mesenteric venous thrombosis: successful treatment by intraarterial lytic therapy. J Vasc Interv Radiol 1999; 10: 98.
69. Sze DY, O'Sullivan GJ, Johnson DL, et al. Mesenteric and portal venous thrombosis treated by transjugular mechanical thrombolysis. AJR Am J Roentgenol 2000; 175: 732.
70. Bilbao JI, Rodriguez-Cabello J, Longo J, et al. Portal thrombosis: percutaneous transhepatic treatment with urokinase -a case report. Gastrointest Radiol 1989; 14: 326.
71. Hildebrand HD, Zierler RE. Mesenteric vascular disease. Am J Surg 1980; 139: 188.
72. Wilson C, Gupta R, Gilmour DG, et al. Acute superior mesenteric ischaemia. Br J Surg 1987; 74: 279.
73. Lobo-Martinez E, Merono CE, Sacco O, et al. Embolectomy in mesenteric ischemia. Rev Esp Enferm Dig 1993; 83: 351.
74. Inderbitzi R, Wagner HE, Seiler C, et al. Acute mesenteric ischaemia. Eur J Surg 1992; 158: 123.
75. Mensink PB, van Petersen AS, Geelkerken RH, et al. Clinical significance of splanchnic artery stenosis. Br J Surg 2006; 93: 1377.
76. Gertsch P, Matthews J, Lerut J, et al. Acute thrombosis of the splanchnic veins. Arch Surg 1993; 128: 341.
77. Jarvinen O, Laurikka J, Sisto T, et al. Atherosclerosis of the visceral arteries. Vasa 1995; 24: 9.
78. Bakker RC, Brandjes DP, Snel P, et al. Malabsorption syndrome associated with ulceration of the stomach and small bowel caused by chronic intestinal ischemia in a patient with hyperhomocysteinemia. Mayo Clin Proc 1997; 72: 546.
79. Liberski SM, Koch KL, Atnip RG, et al. Ischemic gastroparesis: resolution after revascularization. Gastroenterology 1990; 99: 252.
80. Moawad J, Gewertz BL. Chronic mesenteric ischemia. Clinical presentation and diagnosis. Surg Clin North Am 1997; 77: 357.
81. Zwolak RM. Can duplex ultrasound replace arteriography in screening for mesenteric ischemia? Semin Vasc Surg 1999; 12: 252.
82. Jarvinen O, Laurikka J, Sisto T, et al. Intestinal ischemia following surgery for aorto-iliac disease. A review of 502 consecutive aortic reconstructions. Vasa 1996; 25: 148.
83. Thomas JH, Blake K, Pierce GE, et al. The clinical course of asymptomatic mesenteric arterial stenosis. J Vasc Surg 1998; 27: 840.
84. Foley MI, Moneta GL, Abou-Zamzam AM, et al. Revascularization of the superior mesenteric artery alone for treatment of intestinal ischemia. J Vasc Surg 2000; 32: 37.
85. Mateo RB, O'Hara PJ, Hertzer NR, et al. Elective surgical treatment of symptomatic chronic mesenteric occlusive disease: early results and late outcomes. J Vasc Surg 1999; 29: 821.
86. Sheeran SR, Murphy TP, Khwaja A, et al. Stent placement for treatment of mesenteric artery stenoses or occlusions. J Vasc Interv Radiol 1999; 10: 861.
87. Steinmetz E, Tatou E, Favier-Blavoux C, et al. Endovascular treatment as first choice in chronic intestinal ischemia. Ann Vasc Surg 2002; 16: 693.
88. Kasirajan K, O'Hara PJ, Gray BH, et al. Chronic mesenteric ischemia: open surgery versus percutaneous angioplasty and stenting. J Vasc Surg 2001; 33: 63.
89. Higgins PD, Davis KJ, Laine L. Systematic review: the epidemiology of ischaemic colitis. Aliment Pharmacol Ther 2004; 19: 729.
90. Cappell MS. Intestinal (mesenteric) vasculopathy. II. Ischemic colitis and chronic mesenteric ischemia. Gastroenterol Clin North Am 1998; 27: 827.
91. Schuler JG, Hudlin MM. Cecal necrosis: infrequent variant of ischemic colitis. Report of five cases. Dis Colon Rectum 2000; 43: 708.
92. Flobert C, Cellier C, Berger A, et al. Right colonic involvement is associated with severe forms of ischemic colitis and occurs frequently in patients with chronic renal failure requiring hemo dialysis. Am J Gastroenterol 2000; 95: 195.
93. Tollefson DF, Ernst CB. Colon ischemia following aortic reconstruction. Ann Vasc Surg 1991; 5: 485.
94. Geraghty PJ, Sanchez LA, Rubin BG, et al. Overt ischemic colitis after endovascular repair of aortoiliac aneurysms. J Vasc Surg 2004; 40: 413.
95. Toursarkissian B, Thompson RW. Ischemic colitis. Surg Clin North Am 1997; 77: 461.
96. Scharff JR, Longo WE, Vartanian SM, et al. Ischemic colitis: spectrum of disease and outcome. Surgery 2003; 134: 624.
97. Cole JA, Cook SF, Sands BE, et al. Occurrence of colon ischemia in relation to irritable bowel syndrome. Am J Gastroenterol 2004; 99: 486.
98. Brandt LJ, Boley SJ, Mitsudo S. Clinical characteristics and natural history of colitis in the elderly. Am J Gastroenterol 1982; 77: 382.
99. Deana DG, Dean PJ. Reversible ischemic colitis in young women. Association with oral contraceptive use. Am J Surg Pathol 1995; 19: 454.
100. Linder JD, Monkemuller KE, Raijman I, et al. Cocaine-associated ischemic colitis. South Med J 2000; 93: 909.
101. Lucas W, Schroy PC. Reversible ischemic colitis in a high endurance athlete. Am J Gastroenterol 1998; 93: 2231.
102. Ullery BS, Boyko AT, Banet GA, et al. Colonic ischemia: an under-recognized cause of lower gastrointestinal bleeding. J Emerg Med 2004; 27: 1.
103. Barouk J, Gournay J, Bernard P, et al. [Ischemic colitic in the elderly: predictive factors of gangrenous outcome]. Gastroenterol Clin Biol 1999; 23: 470.
104. Boley SJ. Colonic ischemia -25 years later. Am J Gastroenterol 1990; 85: 931.
105. Wittenberg J, Athanasoulis CA, Williams LF, et al. Ischemic colitis. Radiology and pathophysiology. Am J Roentgenol Radium Ther Nucl Med 1975; 123: 287.
106. Longo WE, Ballantyne GH, Gusberg RJ. Ischemic colitis: patterns and prognosis. Dis Colon Rectum 1992; 35: 726.
107. Price AB. Ischaemic colitis. Curr Top Pathol 1990; 81: 229.
108. Iida M, Matsui T, Fuchigami T, et al. Ischemic colitis: serial changes in double-contrast barium enema examination. Radiology 1986; 159: 337.
109. Ko GY, Ha HK, Lee HJ, et al. Usefulness of CT in patients with ischemic colitis proximal to colonic cancer. AJR Am J Roentgenol 1997; 168: 951.
110. Teefey SA, Roarke MC, Brink JA, et al. Bowel wall thickening: differentiation of inflammation from ischemia with color Doppler and duplex US. Radiology 1996; 198: 547.
111. Danse EM, Van Beers BE, Jamart J, et al. Prognosis of ischemic colitis: comparison of color Doppler sonography with early clinical and laboratory findings. AJR Am J Roentgenol 2000; 175: 1151.
112. Greenwald DA, Brandt LJ. Recognizing E. coli O157: H7 infection. Hosp Pract (Minneap) 1997; 32: 123.
113. Crespo MG, Arnal FM, Gomez M, et al. Cytomegalovirus colitis mimicking a colonic neoplasm or ischemic colitis 4 years after heart transplantation. Transplantation 1998; 66: 1562.
114. Su C, Brandt LJ, Sigal SH, et al. The immunohistological diagnosis of E. coli O157: H7 colitis: possible association with colonic ischemia. Am J Gastroenterol 1998; 93: 1055.
115. Dignan CR, Greenson JK. Can ischemic colitis be differentiated from C. difficile colitis in biopsy specimens? Am J Surg Pathol 1997; 21: 706.
116. Mantzaris GJ, Hatzis A, Archavlis E, et al. The role of colonoscopy in the differential diagnosis of acute, severe hemorrhagic colitis. Endoscopy 1995; 27: 645.
117. Carpenter HA, Talley NJ. The importance of clinicopathological correlation in the diagnosis of inflammatory conditions of the colon: histological patterns with clinical implications. Am J Gastroenterol 2000; 95: 878.
118. Seow-Choen F, Chua TL, Goh HS. Ischaemic colitis and colorectal cancer: some problems and pitfalls. Int J Colorectal Dis 1993; 8: 210.
119. Doringer E. Computerized tomography of colonic diverticulitis. Crit Rev Diagn Imaging 1992; 33: 421.
120. Lanas A, Panes J, Pique JM. Clinical implications of COX-1 and/or COX-2 inhibition for the distal gastrointestinal tract. Curr Pharm Des 2003; 9: 2253.
121. Farber MS, Abrams JH. Antibiotics for the acute abdomen. Surg Clin North Am 1997; 77: 1395.
122. Redan JA, Rush BF, Lysz TW, et al. Organ distribution of gut-derived bacteria caused by bowel manipulation or ischemia. Am J Surg 1990; 159: 85.
123. Redaelli CA, Schilling MK, Carrel TP. Intraoperative assessment of intestinal viability by laser Doppler flowmetry for surgery of ruptured abdominal aortic aneurysms. World J Surg 1998; 22: 283.
124. Nakai M, Uchida H, Hanaoka T, et al. Beneficial effects of prostaglandin E1 on ischemic colitis following surgery on the abdominal aorta. Surg Today 1998; 28: 1146.
125. Mortensen FV, Jørgensen B, Christiansen HM, et al. Short-chain fatty acid enemas stimulate plasminogen activator inhibitor-1 after abdominal aortic graft surgery: a double-blinded, placebo-controlled study. Thromb Res 2000; 98: 361.
126. Simi M, Pietroletti R, Navarra L, et al. Bowel stricture due to ischemic colitis: report of three cases requiring surgery. Hepatogastroenterology 1995; 42: 279.
127. Reilly LM, Ammar AD, Stoney RJ, et al. Late results following operative repair for celiac artery compression syndrome. J Vasc Surg 1985; 2: 79.
128. Bech FR. Celiac artery compression syndromes. Surg Clin North Am 1997; 77: 409.
129. Ha HK, Lee SH, Rha SE, et al. Radiologic features of vasculitis involving the gastrointestinal tract. Radiographics 2000; 20: 779.
130. Harada M, Yoshida H, Ikeda H, et al. Polyarthritis nodosa with mesenteric aneurysms demonstrated by angiography: report of a case and successful treatment of the patient with prednisolone and cyclophosphamide. J Gastroenterol 1999; 34: 702.
131. Cappell MS, Seibold JR. Mesenteric thrombosis associated with anticardiolipin antibodies in a patient with systemic lupus erythematosus. Am J Gastroenterol 1992; 87: 520.
132. Vega Saenz JL, Barajas Martinez JM, Torres AM. Ischemic colitis as manifestation of Takayasu arteritis. Gastroenterol Hepatol 1995; 18: 326.
133. Hassoun Z, Lacrosse M, De Ronde T. Intestinal involvement in Buerger's disease. J Clin Gastroenterol 2001; 32: 85.
134. Chubachi A, Saitoh K, Imai H, et al. Case report: intestinal infarction after an aneurysmal occlusion of superior mesenteric artery in a patient with Behcet's disease. Am J Med Sci 1993; 306: 376.
135. Hudson M, Chitolie A, Hutton RA, et al. Thrombotic vascular risk factors in inflammatory bowel disease. Gut 1996; 38: 733.
136. Mallory A, Struthers JE, Kern F. Persistent hypotension and intestinal infarction in a patient with primary amyloidosis. Gastroenterology 1975; 68: 1587.
137. Nimmo GR, McInnes G, Turner AR, et al. Severe mesenteric ischemia due to primary thrombocythemia treated with prostacyclin. Crit Care Med 1990; 18: 889.
138. Balian A, Veyradier A, Naveau S, et al. Prothrombin 20210G/A mutation in two patients with mesenteric ischemia. Dig Dis Sci 1999; 44: 1910.
139. Matsushita I, Hanai H, Sato Y, et al. Protein-losing enteropathy caused by mesenteric venous thrombosis with protein C deficiency. J Clin Gastroenterol 2000; 30: 94.
140. Peters TG, Lewis JD, Flip DJ, et al. Antithrombin III deficiency causing postsplenectomy mesenteric venous thrombosis coincident with thrombocytopenia. Ann Surg 1977; 185: 229.
141. Yee NS, Guerry D, Lichtenstein GR. Ischemic colitis associated with factor V Leiden mutation. Ann Intern Med 2000; 132: 595.
142. Hassan HA. Oral contraceptive-induced mesenteric venous thrombosis with resultant intestinal ischemia. J Clin Gastroenterol 1999; 29: 90.
143. Muniz AE, Evans T. Acute gastrointestinal manifestations associated with use of crack. Am J Emerg Med 2001; 19: 61.
144. Krupski WC, Selzman CH, Whitehill TA. Unusual causes of mesenteric ischemia. Surg Clin North Am 1997; 77: 471.
145. Lambert M, de Peyer R, Muller AF. Reversible ischemic colitis after intravenous vasopressin therapy. JAMA 1982; 247: 666.
146. Panés J, Piqué JM, Bordas JM, et al. Reduction of gastric hyperemia by glypressin and vasopressin administration in cirrhotic patients with portal hypertensive gastropathy. Hepatology 1994; 19: 55.
147. Friedel D, Thomas R, Fisher RS. Ischemic colitis during treatment with alosetron. Gastroenterology 2001; 120: 557.
148. Pompili M, Pizzolante F, Larocca LM, et al. Ischaemic jejunal vasculitis during treatment with pegylated interferon-alpha 2b and ribavirin for hepatitis C virus related cirrhosis. Dig Liver Dis 2006; 38: 352.