Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis

International Journal of Pharmaceutics

Volumn 443, Issue 1-2, 2013, Pages 175-182

  Liu, Lei ^a   Sun, Lu ^a   Wu, Qinjie ^a   Guo, Wenhao ^a   Li, Ling ^a   Chen, Yishan ^a   Li, Yuchen ^a   Gong, Changyang ^a   Qian, Zhiyong ^a   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Biodegradable; Breast tumor; Curcumin; Micelle; Spontaneous pulmonary metastasis

Indexed keywords

CURCUMIN; CURCUMIN LOADED BIODEGRADABLE SELF ASSEMBLED POLYMERIC MICELLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST TUMOR; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; ENCAPSULATION; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG METASTASIS; MICROVASCULATURE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TUMOR GROWTH;

ANALYSIS OF VARIANCE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CURCUMIN; DRUG CARRIERS; FEMALE; IN SITU NICK-END LABELING; LUNG NEOPLASMS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICELLES; NEOVASCULARIZATION, PATHOLOGIC; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SOLUBILITY; SURFACE PROPERTIES;

EID: 84873043646     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.032     Document Type: Article

References (27)

1. T.M. Allen, and P.R. Cullis Drug delivery systems: entering the mainstream Science 303 2004 1818 1822
2. P. Anand, A.B. Kunnumakkara, R.A. Newman, and B.B. Aggarwal Bioavailability of curcumin: problems and promises Mol. Pharm. 4 2007 807 818
3. D. Armstrong, B. Bundy, L. Wenzel, H. Huang, R. Baergen, S. Lele, L. Copeland, J. Walker, and R. Burger Intraperitoneal cisplatin and paclitaxel in ovarian cancer N. Engl. J. Med. 354 2006 34 43
4. J.S. Chawla, and M.M. Amiji Biodegradable poly(ε-caprolactone) nanoparticles for tumor-targeted delivery of tamoxifen Int. J. Pharm. 249 2002 127 138
5. J. Fang, H. Nakamura, and H. Maeda The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect Adv. Drug Deliv. Rev. 63 2011 136 151
6. O.C. Farokhzad, J. Cheng, B.A. Teply, I. Sherifi, S. Jon, P.W. Kantoff, J.P. Richie, and R. Langer Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo Proc. Natl. Acad. Sci. U.S.A. 103 2006 6315 6320
7. C.Y. Gong, S.A. Shi, P.W. Dong, B. Kan, M.L. Gou, X.H. Wang, X.Y. Li, F. Luo, X. Zhao, Y.Q. Wei, and Z.Y. Qian Synthesis and characterization of PEG-PCL-PEG thermosensitive hydrogel Int. J. Pharm. 365 2009 89 99
8. C.Y. Gong, X.W. Wei, X.H. Wang, Y.J. Wang, G. Guo, Y.Q. Mao, F. Luo, and Z.Y. Qian Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization Nanotechnology 21 2010 215103
9. C.Y. Gong, Y.J. Wang, X.H. Wang, X.W. Wei, Q.J. Wu, B.L. Wang, P.W. Dong, L.J. Chen, F. Luo, and Z.Y. Qian Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic drug delivery, part 2: in vitro and in vivo toxicity evaluation J. Nanopart. Res. 13 2011 721 731
10. C.Y. Gong, C. Wang, Y.J. Wang, Q.J. Wu, D.D. Zhang, F. Luo, and Z.Y. Qian Efficient inhibition of colorectal peritoneal carcinomatosis by drug loaded micelles in thermosensitive hydrogel composites Nanoscale 4 2012 3095 3104
11. C.Y. Gong, Y. Xie, Q.J. Wu, Y. Wang, S. Deng, D. Xiong, L. Liu, M. Xiang, Z. Qian, and Y. Wei Improving antitumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma Nanoscale 4 2012 6004 6017
12. C.Y. Gong, B. Yang, Z.Y. Qian, X. Zhao, Q.J. Wu, X.R. Qi, Y.J. Wang, G. Guo, B. Kan, F. Luo, and Y.Q. Wei Improving intraperitoneal chemotherapeutic effect and preventing postsurgical adhesions simultaneously with biodegradable micelles Nanomed-Nanotechnol 8 2012 963 973
13. M.L. Gou, K. Men, H.S. Shi, M.L. Xiang, J. Zhang, J. Song, J.L. Long, Y. Wan, F. Luo, and X. Zhao Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo Nanoscale 3 2011 1558 1567
14. J. Halder, A.A. Kamat, C.N. Landen Jr., L.Y. Han, S.K. Lutgendorf, Y.G. Lin, W.M. Merritt, N.B. Jennings, A. Chavez-Reyes, R.L. Coleman, D.M. Gershenson, R. Schmandt, S.W. Cole, G. Lopez-Berestein, and A.K. Sood Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy Clin. Cancer Res. 12 2006 4916 4924
15. K.L. Hennenfent, and R. Govindan Novel formulations of taxanes: a review. Old wine in a new bottle? Ann. Oncol. 17 2006 735 749
16. X. Huang, M.K. Wong, H. Yi, S. Watkins, A.D. Laird, S.F. Wolf, and E. Gorelik Combined therapy of local and metastatic 4T1 breast tumor in mice using SU6668, an inhibitor of angiogenic receptor tyrosine kinases, and the immunostimulator B7. 2-IgG fusion protein Cancer Res. 62 2002 5727 5735
17. G.C. Jagetia, and B.B. Aggarwal Spicing up of the immune system by curcumin J. Clin. Immunol. 27 2007 19 35
18. L. Li, F.S. Braiteh, and R. Kurzrock Liposome-encapsulated curcumin Cancer 104 2005 1322 1331
19. J. Liu, Y. Wei, L. Yang, X. Zhao, L. Tian, J. Hou, T. Niu, F. Liu, Y. Jiang, and B. Hu Immunotherapy of tumors with vaccine based on quail homologous vascular endothelial growth factor receptor-2 Blood 102 2003 1815 1823
20. R.K. Maheshwari, A.K. Singh, J. Gaddipati, and R.C. Srimal Multiple biological activities of curcumin: a short review Life Sci. 78 2006 2081 2087
21. C. Oerlemans, W. Bult, M. Bos, G. Storm, J.F.W. Nijsen, and W.E. Hennink Polymeric micelles in anticancer therapy: targeting, imaging and triggered release Pharm. Res. 27 2010 2569 2589
22. A. Safavy, K.P. Raisch, S. Mantena, L.L. Sanford, S.W. Sham, N.R. Krishna, and J.A. Bonner Design and development of water-soluble curcumin conjugates as potential anticancer agents J. Med. Chem. 50 2007 6284 6288
23. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2012 CA Cancer J. Clin. 62 2012 10 29
24. S. Singh From exotic spice to modern drug? Cell 130 2007 765 768
25. H. Tang, C.J. Murphy, B. Zhang, Y. Shen, E.A. Van Kirk, W.J. Murdoch, and M. Radosz Curcumin polymers as anticancer conjugates Biomaterials 31 2010 7139 7149
26. V. Wagner, A. Dullaart, A.-K. Bock, and A. Zweck The emerging nanomedicine landscape Nat. Biotechnol. 24 2006 1211 1217
27. M.M. Yallapu, M. Jaggi, and S.C. Chauhan Curcumin nanoformulations: a future nanomedicine for cancer Drug Discov. Today 17 2012 71 80