Shape of vaginal suppositories affects willingness-to-try and preference

Antiviral Research

Volumn 97, Issue 3, 2013, Pages 280-284

  Li, Bangde ^a   Zaveri, Toral ^a   Ziegler, Gregory R ^a   Hayes, John E ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Acceptability; Consumer behavior; Just about right (JAR) scale; Microbicide; Product optimization; Sensory perception

Indexed keywords

MICROBICIDE;

ARTICLE; ATTITUDE; DRUG FORMULATION; DRUG PREFERENCE; FEMALE; HUMAN; INTRAVAGINAL DRUG ADMINISTRATION; JUST ABOUT RIGHT SCALE; MAJOR CLINICAL STUDY; PERCEPTION; PRIORITY JOURNAL; RATING SCALE; TAMPON; VISUAL ANALOG SCALE; WILLINGNESS TO TRY;

ADMINISTRATION, INTRAVAGINAL; ADULT; ANTI-INFECTIVE AGENTS; ATTITUDE; FEMALE; HUMANS; PATIENT PREFERENCE; SEXUALLY TRANSMITTED DISEASES; SUPPOSITORIES; YOUNG ADULT;

EID: 84873040164     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2012.12.024     Document Type: Article

References (30)

1. Abdool Karim Q., Abdool Karim S.S., Frohlich J.A., Grobler A.C., Baxter C., Mansoor L.E., Kharsany A.B., Sibeko S., Mlisana K.P., Omar Z., Gengiah T.N., Maarschalk S., Arulappan N., Mlotshwa M., Morris L., Taylor D. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010, 329:1168-1174.
2. AMD, 2009. Microbicide Pipeline Summary Report.
3. Carballo-Dieguez A., Giguere R., Dolezal C., Chen B.A., Kahn J., Zimet G., Mabragana M., Leu C.S., McGowan I. "Tell Juliana": acceptability of the candidate microbicide vivagel® and two placebo gels among ethnically diverse, sexually active young women participating in a phase 1 microbicide study. AIDS Behav. 2012, 16:1761-1774.
4. Elias C., Coggins C. Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: where have we been? Where are we going?. Journal of Women Health Gen-B 2001, 10:163-173.
5. Giguere R., Carballo-Dieguez A., Ventuneac A., Mabragana M., Dolezal C., Chen B.A., Kahn J.A., Zimet G.D., McGowan I. Variations in microbicide gel acceptability among young women in the USA and Puerto Rico. Culture Health & Sexuality 2012, 14:151-166.
6. Lawless H.T., Heymann H. Sensory Evaluation of Food Principles and Practices, Food Science Text Series 2010, Springer, New York. Second ed.
7. Li, B., Zaveri, T., Ziegler, G.E., Hayes, J.E., 2013. User preferences in a carrageenan-based vaginal drug delivery system. PLoS One. 8(1). Epub 24 Jan 2013. http://dx.doi.org/10.1371/journal.pone.0054975.
8. Mahan E.D., Morrow K.M., Hayes J.E. Quantitative perceptual differences among over-the-counter vaginal products using a standardized methodology: implications for microbicide development. Contraception 2011, 84:184-193.
9. Mantell J.E., Myer L., Carballo-Dieguez A., Stein Z., Ramjee G., Morar N.S., Harrison P.F. Microbicide acceptability research: current approaches and future directions. Social Science & Medicine 2005, 60:319-330.
10. Masse B.R., Boily M.C., Dimitrov D., Desai K. Efficacy dilution in randomized placebo-controlled vaginal microbicide trials. Emerging Themes in Epidemiology 2009, 6:5.
11. Mensch B.S., van der Straten A., Katzen L.L. Acceptability in microbicide and PrEP trials: current status and a reconceptualization. Current Opinion HIV AIDS 2012, 7:534-541.
12. Meullenet J.-F., Xiong R., Findlay C. Analysis of just about right data. Multivariate and Probabilistic Analyses of Sensory Science Problems 2007, Wiley-Blackwell, pp. 207-235.
13. Morrow K., Rosen R., Richter L., Emans A., Forbes A., Day J., Morar N., Maslankowski L., Profy A.T., Kelly C., Karim S.S.A., Mayer K.H. The acceptability of an investigational vaginal microbicide, PRO 2000 gel, among women in a phase I clinical trial. Journal of Women's Health 2003, 12:655-666.
14. Morrow K.M., Fava J.L., Rosen R.K., Christensen A.L., Vargas S., Barroso C. Willingness to use microbicides varies by race/ethnicity, experience with prevention products, and partner type. Health Psychology 2007, 26:777-786.
15. Morrow K.M., Hendrix C. Clinical evaluation of microbicide formulations. Antiviral Research 2010, 88:S40-S46.
16. Morrow K.M., Ruiz M.S. Assessing microbicide acceptability: a comprehensive and integrated approach. AIDS and Behavior 2008, 12:272-283.
17. Nel A.M., Mitchnick L.B., Risha P., Muungo L.T.M., Norick P.M. Acceptability of vaginal film, soft-gel capsule, and tablet as potential microbicide delivery methods among african women. Journal of Women's Health 2011, 20:1207-1214.
18. Popper R., Kroll R.D. Just-About-Right Scales in Consumer Research. ChemoSense 2005, 7:3-6.
19. Raghubir P., Krishna A. Vital dimensions in volume perception: can the eye fool the stomach?. Journal of Marketing Research 1999, 36:313-326.
20. Ramjee G., Morar N.S., Braunstein S., Friedland B., Jones H., van de Wijgert J. Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa. AIDS Research and Therapy 2007, 4:20.
21. Rothman L., Parker M.J. Just about Right (Jar) Scales: Design, Usage, Benefits, and Risks 2009, American Society for Testing & Materials.
22. Severy L.J., Tolley E., Woodsong C., Guest G. A framework for examining the sustained acceptability of microbicides. AIDS and Behavior 2005, 9:121-131.
23. Stone A. Microbicides: a new approach to preventing HIV and other sexually transmitted infections. Nature Reviews Drug Discovery 2002, 1:977-985.
24. Stone H., Sidel J.L. Sensory Evaluation Practices 2004, Elsevier Academic Press.
25. UNAIDS, 2011. Epidemic update and health sector progress towards Universal Access. Progress Report 2011.
26. Ventuneac A., Carballo-Dieguez A., McGowan I., Dennis R., Adler A., Khanukhova E., Price C., Saunders T., Siboliban C., Anton P. Acceptability of UC781 gel as a rectal microbicide among HIV-Uninfected women and men. AIDS and Behavior 2010, 14:618-628.
27. Wansink B., Van Ittersum K. Bottoms up! The influence of elongation on pouring and consumption volume. Journal of Consumer Research 2003, 30:455-463.
28. Whitehead S.J., Kilmarx P.H., Blanchard K., Manopaiboon C., Chaikummao S., Friedland B., Achalapong J., Wankrairoj M., Mock P., Thanprasertsuk S., Tappero J.W. Acceptability of Carraguard vaginal gel use among Thai couples. AIDS 2006, 20:2141-2148.
29. Xiong R., Meullenet J.F. A PLS dummy variable approach to assess the impact of jar attributes on liking. Food Quality and Preference 2006, 17:188-198.
30. Zaveri, T., Powell, K.A., Li, B., Hayes, J.E., Ziegler, G.R., 2012. Improving acceptability of vaginal drug delivery systems by using sensory methods. The Society of Sensory Professionals 3rd Technical and Professional Conference. Jersey City, New Jersey.