Effect of hypoxic-ischemic insults on the composition of fatty acids in the brain of neonatal rats

Annals of Nutrition and Metabolism

Volumn 62, Issue 2, 2013, Pages 123-128

  Suganuma, Hiroki ^a   Okumura, Akihisa ^a   Kitamura, Yohei ^b   Shoji, Hiromichi ^a   Shimizu, Toshiaki ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MORINAGA MILK INDUSTRY CO LTD   (Japan)

Author keywords

Docosahexaenoic acid; Fatty acid; Hypoxic ischemic encephalopathy; Neonate

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; DOCOSAPENTAENOIC ACID; FATTY ACID; LINOLEIC ACID; OMEGA 6 FATTY ACID; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN GROWTH; BRAIN WEIGHT; BRAIN WEIGHT GAIN; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; LEFT COMMON CAROTID ARTERY; LIPID COMPOSITION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; WEIGHT GAIN;

RATTUS;

EID: 84873035132     PISSN: 02506807     EISSN: 14219697     Source Type: Journal    
DOI: 10.1159/000346069     Document Type: Article

References (32)

1. Svennerholm L. Distribution and fatty acid composition of phosphoglycerides in normal human brain. J Lipid Res 1968; 9: 570-579
2. Sinclair AJ. Long-chain polyunsaturated fatty acids in the mammalian brain. Proc Nutr Soc 1975; 34: 287-291
3. Svennerholm L, Vanier MT. The distribution of lipids in the human nervous system. 3. Fatty acid composition of phosphoglycerides of human foetal and infant brain. Brain Res 1973; 50: 341-351
4. Martinez M, Mougan I. Fatty acid composition of human brain phospholipids during normal development. J Neurochem 1998; 71: 2528-2533
5. Clandinin MT, Chappell JE, Leong S, Heim T, Swyer PR, Chance GW. Extrauterine fatty acid accretion in infant brain: implications for fatty acid requirements. Early Hum Dev 1980; 4: 131-138
6. Clandinin MT, Chappell JE, Leong S, Heim T, Swyer PR, Chance GW. Intrauterine fatty acid accretion rates in human brain: implications for fatty acid requirements. Early Hum Dev 1980; 4: 121-129
7. Green P, Yavin E. Fatty acid composition of late embryonic and early postnatal rat brain. Lipids 1996; 31: 859-865
8. Gamoh S, Hashimoto M, Sugioka K, Shahdat Hossain M, Hata N, Misawa Y, Masumura S. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience 1999; 93: 237-241
9. Yoshida S, Yasuda A, Kawazato H, Sakai K, Shimada T, Takeshita M, Yuasa S, Kobayashi T, Watanabe S, Okuyama H. Synaptic vesicle ultrastructural changes in the rat hippocampus induced by a combination of alpha-linolenate deficiency and a learning task. J Neurochem 1997; 68: 1261-1268
10. Uauy RD, Birch DG, Birch EE, Tyson JE, Hoffman DR. Effect of dietary omega-3 fatty acids on retinal function of very-lowbirth-weight neonates. Pediatr Res 1990; 28: 485-492
11. Helland IB, Smith L, Saarem K, Saugstad OD, Drevon CA. Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age. Pediatrics 2003; 111: e39-e44
12. Morse NL. Benefits of docosahexaenoic acid, folic acid, vitamin D and iodine on foetal and infant brain development and function following maternal supplementation during pregnancy and lactation. Nutrients 2012; 4: 799-840
13. Johnston MV, Fatemi A, Wilson MA, Northington F. Treatment advances in neonatal neuroprotection and neurointensive care. Lancet Neurol 2011; 10: 372-382
14. Bas O, Songur A, Sahin O, Mollaoglu H, Ozen OA, Yaman M, Eser O, Fidan H, Yagmurca M. The protective effect of fish n-3 fatty acids on cerebral ischemia in rat hippocampus. Neurochem Int 2007; 50: 548-554
15. Wang X, Zhao X, Mao ZY, Wang XM, Liu ZL. Neuroprotective effect of docosahexaenoic acid on glutamate-induced cytotoxicity in rat hippocampal cultures. Neuroreport 2003; 14: 2457-2461
16. Rice JE 3rd, Vannucci RC, Brierley JB. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 1981; 9: 131-141
17. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911-917
18. Juaneda P, Rocquelin G. Rapid and convenient separation of phospholipids and nonphosphorus lipids from rat heart using silica cartridges. Lipids 1985; 20: 40-41
19. American Oil Chemists' Society: Fatty acid composition by GLC. AOCS official method Ce 1b-89; in American Oil Chemists' Society: Official Methods and Recommended Practices of the AOCS, ed 5. Champaign, AOSC Press, 1997
20. Crawford MA, Hassam AG, Williams G. Essential fatty acids and fetal brain growth. Lancet 1976; i: 452-453
21. Uauy R, Dangour AD. Nutrition in brain development and aging: role of essential fatty acids. Nutr Rev 2006; 64: S24-S33, discussion S72-S91
22. Jensen CL, Voigt RG, Prager TC, Zou YL, Fraley JK, Rozelle JC, Turcich MR, Llorente AM, Anderson RE, Heird WC. Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed term infants. Am J Clin Nutr 2005; 82: 125-132
23. Low JA, Handley-Derry MH, Burke SO, Peters RD, Pater EA, Killen HL, Derrick EJ. Association of intrauterine fetal growth retardation and learning deficits at age 9 to 11 years. Am J Obstet Gynecol 1992; 167: 1499-1505
24. Wolke D, Samara M, Bracewell M, Marlow N. Specific language difficulties and school achievement in children born at 25 weeks of gestation or less. J Pediatr 2008; 152: 256-262
25. Burdge GC, Dunn RL, Wootton SA, Jackson AA. Effect of reduced dietary protein intake on hepatic and plasma essential fatty acid concentrations in the adult female rat: effect of pregnancy and consequences for accumulation of arachidonic and docosahexaenoic acids in fetal liver and brain. Br J Nutr 2002; 88: 379-387
26. Sauerwald TU, Hachey DL, Jensen CL, Chen H, Anderson RE, Heird WC. Intermediates in endogenous synthesis of C22: 6 omega 3 and C20: 4 omega 6 by term and preterm infants. Pediatr Res 1997; 41: 183-187
27. Uauy R, Mena P, Wegher B, Nieto S, Salem N Jr. Long chain polyunsaturated fatty acid formation in neonates: effect of gestational age and intrauterine growth. Pediatr Res 2000; 47: 127-135
28. Voss A, Reinhart M, Sankarappa S, Sprecher H. The metabolism of 7, 10, 13, 16, 19-docosapentaenoic acid to 4, 7, 10, 13, 16, 19-docosahexaenoic acid in rat liver is independent of a 4-desaturase. J Biol Chem 1991; 266: 19995-20000
29. Martinez M. Severe deficiency of docosahexaenoic acid in peroxisomal disorders: a defect of delta 4 desaturation?. Neurology 1990; 40: 1292-1298
30. Kremser K, Kremser-Jezik M, Singh I. Effect of hypoxia-reoxygenation on peroxisomal functions in cultured human skin fibroblasts from control and Zellweger syndrome patients. Free Radic Res 1995; 22: 39-46
31. Wainwright PE, Xing HC, Mutsaers L, Mc-Cutcheon D, Kyle D. Arachidonic acid offsets the effects on mouse brain and behavior of a diet with a low (n-6): (n-3) ratio and very high levels of docosahexaenoic acid. J Nutr 1997; 127: 184-193
32. Fidler N, Sauerwald T, Pohl A, Demmelmair H, Koletzko B. Docosahexaenoic acid transfer into human milk after dietary supplementation: a randomized clinical trial. J Lipid Res 2000; 41: 1376-1383