메뉴 건너뛰기




Volumn 24, Issue 1, 2013, Pages 154-163

The (Un)certainty of selectivity in liquid chromatography tandem mass spectrometry

Author keywords

Confirmation; Identification; Liquid chromatography; Mass spectrometry; Precursor ion; Product ion; Retention time; Selectivity; Uncertainty

Indexed keywords

ACQUISITION MODES; CONFIRMATION; EMPIRICAL MODEL; FALSE POSITIVE; LC-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; PROBABILITY ESTIMATION; RETENTION TIME; UNCERTAINTY;

EID: 84873034999     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0501-0     Document Type: Article
Times cited : (50)

References (54)
  • 2
    • 78651488361 scopus 로고    scopus 로고
    • Issues in mass spectrometry between bench chemists and regulatory laboratory managers: Summary of the roundtable on mass spectrometry held at the 123rd AOAC International Annual Meeting
    • 1:CAS:528:DC%2BC3cXhsVCit7zL
    • Heller, D.N.; Lehotay, S.J.; Martos, P.A.; Hammack, W.; Fernndez-Alba, A.R.: Issues in mass spectrometry between bench chemists and regulatory laboratory managers: Summary of the roundtable on mass spectrometry held at the 123rd AOAC International Annual Meeting. J. AOAC Int. 93(5), 1625-1632 (2010)
    • (2010) J. AOAC Int. , vol.93 , Issue.5 , pp. 1625-1632
    • Heller, D.N.1    Lehotay, S.J.2    Martos, P.A.3    Hammack, W.4    Fernndez-Alba, A.R.5
  • 3
    • 5344271213 scopus 로고    scopus 로고
    • Substance identification: The weak link in analytical toxicology
    • De Zeeuw, R.A.: Substance identification: the weak link in analytical toxicology. J. Chromatogr. B 811, 3-12 (2004)
    • (2004) J. Chromatogr. B , vol.811 , pp. 3-12
    • De Zeeuw, R.A.1
  • 4
    • 0013285756 scopus 로고    scopus 로고
    • Commission Decision 2002/657/EC implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results
    • Commission Decision 2002/657/EC implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off. J. Europ. Commun. L221, 8-36 (2002)
    • (2002) Off. J. Europ. Commun. , vol.221 , pp. 8-36
  • 8
    • 0003646753 scopus 로고    scopus 로고
    • IOC, International Olympic Committee Internal communication to IOC accreditated laboratories, Lausanne, Switzerland
    • IOC, International Olympic Committee. Analytical criteria for reporting low concentrations of anabolic steroids. Internal communication to IOC accreditated laboratories, Lausanne, Switzerland (1998)
    • (1998) Analytical Criteria for Reporting Low Concentrations of Anabolic Steroids
  • 11
    • 0018008685 scopus 로고
    • Use of mass spectrometry for confirmation of animal drug residues
    • Sphon, J.A.: Use of mass spectrometry for confirmation of animal drug residues. J. Assoc. Off. Anal. Chem. 81(5), 1247-1252 (1978)
    • (1978) J. Assoc. Off. Anal. Chem. , vol.81 , Issue.5 , pp. 1247-1252
    • Sphon, J.A.1
  • 12
    • 56549110611 scopus 로고    scopus 로고
    • Identification and confirmation of chemical residues in food by chromatography-mass spectrometry and other techniques
    • 10.1016/j.trac.2008.10.004 1:CAS:528:DC%2BD1cXhsVKhsLzN
    • Lehotay, S.J.; Mastovska, K.; Amirav, A.; Fialkov, A.B.; Martos, P.A.; de Kok, A.; Fernández-Alba, A.R.: Identification and confirmation of chemical residues in food by chromatography-mass spectrometry and other techniques. TrAC - Trend Anal. Chem. 27(11), 1070-1090 (2008)
    • (2008) TrAC - Trend Anal. Chem. , vol.27 , Issue.11 , pp. 1070-1090
    • Lehotay, S.J.1    Mastovska, K.2    Amirav, A.3    Fialkov, A.B.4    Martos, P.A.5    De Kok, A.6    Fernández-Alba, A.R.7
  • 14
    • 84873030126 scopus 로고    scopus 로고
    • National Institute of Standards and Technology Accessed 4 April 2012
    • National Institute of Standards and Technology. NIST '05. 2005. Available at: http://webbook.nist.gov/chemistry/ Accessed 4 April 2012
    • (2005) NIST '05
  • 15
    • 0003178708 scopus 로고    scopus 로고
    • Council Directive 96/23/EC on measures to monitor certain substances and residues thereof in live animals and animal products and repealing Directives 85/358/EEC and 86/469/EEC and Decisions 89/187/EEC and 91/664/EEC off
    • Council Directive 96/23/EC on measures to monitor certain substances and residues thereof in live animals and animal products and repealing Directives 85/358/EEC and 86/469/EEC and Decisions 89/187/EEC and 91/664/EEC Off. J. Europ. Commun. L125, 10-32 (1996)
    • (1996) J. Europ. Commun. , vol.125 , pp. 10-32
  • 16
    • 0034446047 scopus 로고    scopus 로고
    • Identification of residues by LC-MS. The application of new EU guidelines
    • 10.1051/analusis:2000280947 1:CAS:528:DC%2BD3MXjtFOjurc%3D
    • Stolker, A.A.M.; Stephany, R.W.; van Ginkel, L.A.: Identification of residues by LC-MS. The application of new EU guidelines. Analusis 28(10), 947-951 (2000)
    • (2000) Analusis , vol.28 , Issue.10 , pp. 947-951
    • Stolker, A.A.M.1    Stephany, R.W.2    Van Ginkel, L.A.3
  • 17
    • 33646401510 scopus 로고    scopus 로고
    • On the risk of false positive identification using multiple ion monitoring in qualitative mass spectrometry: Large-scale intercomparisons with a comprehensive mass spectral library
    • 10.1016/j.jasms.2006.02.021 1:CAS:528:DC%2BD28XkvVSlsbs%3D
    • Stein, S.; Heller, D.: On the risk of false positive identification using multiple ion monitoring in qualitative mass spectrometry: Large-scale intercomparisons with a comprehensive mass spectral library. J. Am. Soc. Mass Spectrom. 17(6), 823-835 (2006)
    • (2006) J. Am. Soc. Mass Spectrom. , vol.17 , Issue.6 , pp. 823-835
    • Stein, S.1    Heller, D.2
  • 18
    • 61849087218 scopus 로고    scopus 로고
    • Validation of multiresidue methods for veterinary drug residues; Related problems and posible solutions
    • 10.1016/j.aca.2008.09.033 1:CAS:528:DC%2BD1MXjt1Kit7k%3D
    • Kaufmann, A.: Validation of multiresidue methods for veterinary drug residues; related problems and posible solutions. Anal. Chim. Acta 637, 144-155 (2009)
    • (2009) Anal. Chim. Acta , vol.637 , pp. 144-155
    • Kaufmann, A.1
  • 19
    • 63449114767 scopus 로고    scopus 로고
    • Are liquid chromatography/electrospray tandem quadrupole fragmentation ratios unequivocal confirmation criteria? Rapid Commun
    • 1:CAS:528:DC%2BD1MXjvFahu7w%3D
    • Kaufmann, A.; Butcher, P.; Maden, K.; Widmer, M.; Giles, K.; Uría, D.: Are liquid chromatography/electrospray tandem quadrupole fragmentation ratios unequivocal confirmation criteria? Rapid Commun. Mass Spectrom. 23(7), 985-998 (2009)
    • (2009) Mass Spectrom. , vol.23 , Issue.7 , pp. 985-998
    • Kaufmann, A.1    Butcher, P.2    Maden, K.3    Widmer, M.4    Giles, K.5    Uría, D.6
  • 20
    • 65749091878 scopus 로고    scopus 로고
    • False-positive liquid chromatography/tandem mass spectrometric confirmation of sebuthylazine residues using the identification points system according to EU directive 2002/657/EC due to a biogenic insecticide in tarragon
    • 10.1002/rcm.3982
    • Schürmann, A.; Dvorak, V.; Crüzer, C.; Butcher, P.; Kaufmann, A.: False-positive liquid chromatography/tandem mass spectrometric confirmation of sebuthylazine residues using the identification points system according to EU directive 2002/657/EC due to a biogenic insecticide in tarragon. Rapid Commun. Mass Spectrom. 23(8), 1196-1200 (2009)
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.8 , pp. 1196-1200
    • Schürmann, A.1    Dvorak, V.2    Crüzer, C.3    Butcher, P.4    Kaufmann, A.5
  • 21
    • 33646826389 scopus 로고    scopus 로고
    • Proficiency study for the determination of nitrofuran metabolites in shrimps
    • 10.1080/02652030500460534 1:CAS:528:DC%2BD28Xks1Oqur8%3D
    • Hurtaud-Pessel, D.; Verdon, E.; Blot, J.; Sanders, P.: Proficiency study for the determination of nitrofuran metabolites in shrimps. Food Add. Contam. 23(6), 569-578 (2006)
    • (2006) Food Add. Contam. , vol.23 , Issue.6 , pp. 569-578
    • Hurtaud-Pessel, D.1    Verdon, E.2    Blot, J.3    Sanders, P.4
  • 22
    • 84873020463 scopus 로고    scopus 로고
    • Accessed 7 Oct 2011
    • Emolecules database, 2011. Available at: http://www.emolecules.com/doc/ Accessed 7 Oct 2011
    • (2011) Emolecules Database
  • 24
    • 13844254549 scopus 로고    scopus 로고
    • LC-MS/MS method for the confirmatory determination of aromatic amines and its application in textile analysis
    • 10.1007/s00216-004-2852-2 1:CAS:528:DC%2BD2MXht1GhtLw%3D
    • Sutthivaiyakit, P.; Achatz, S.; Lintelmann, J.; Aungpradit, T.; Chanwirat, R.; Chumanee, S.; Kettrup, A.: LC-MS/MS method for the confirmatory determination of aromatic amines and its application in textile analysis. Anal. Bioanal. Chem. 381(1), 268-276 (2005)
    • (2005) Anal. Bioanal. Chem. , vol.381 , Issue.1 , pp. 268-276
    • Sutthivaiyakit, P.1    Achatz, S.2    Lintelmann, J.3    Aungpradit, T.4    Chanwirat, R.5    Chumanee, S.6    Kettrup, A.7
  • 25
    • 0038607021 scopus 로고    scopus 로고
    • Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry
    • 10.1002/rcm.1052 1:CAS:528:DC%2BD3sXltFals7c%3D
    • Antignac, J.-P.; Cariou, R.; Le Bizec, B.; Cravedi, J.-P.; Andre, F.: Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry. Rapid Commun. Mass Spectrom. 17(12), 1256-1264 (2003)
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , Issue.12 , pp. 1256-1264
    • Antignac, J.-P.1    Cariou, R.2    Le Bizec, B.3    Cravedi, J.-P.4    Andre, F.5
  • 26
    • 56449094066 scopus 로고    scopus 로고
    • Large-scale multi-residue methods for pesticides and their degradation products in food by advanced LC-MS
    • 10.1016/j.trac.2008.09.009
    • Fernández-Alba, A.R.; García-Reyes, J.F.: Large-scale multi-residue methods for pesticides and their degradation products in food by advanced LC-MS. TrAC - Trend. Anal. Chem. 27(11), 973-990 (2008)
    • (2008) TrAC - Trend. Anal. Chem. , vol.27 , Issue.11 , pp. 973-990
    • Fernández-Alba, A.R.1    García-Reyes, J.F.2
  • 28
    • 79954443457 scopus 로고    scopus 로고
    • Development of the first metabolite-based LC-MS(n) urine drug screening procedure-exemplified for antidepressants
    • 10.1007/s00216-010-4398-9 1:CAS:528:DC%2BC3cXhsVWqtbvM
    • Wissenbach, D.; Meyer, M.; Remane, D.; Weber, A.; Maurer, H.: Development of the first metabolite-based LC-MS(n) urine drug screening procedure-exemplified for antidepressants. Anal. Bioanal. Chem. 400(1), 79-88 (2011)
    • (2011) Anal. Bioanal. Chem. , vol.400 , Issue.1 , pp. 79-88
    • Wissenbach, D.1    Meyer, M.2    Remane, D.3    Weber, A.4    Maurer, H.5
  • 29
    • 79958850026 scopus 로고    scopus 로고
    • Fragmentation of toxicologically relevant drugs in positive-ion liquid chromatography-tandem mass spectrometry
    • 10.1002/mas.20332 1:CAS:528:DC%2BC3MXnt1alsbo%3D
    • Niessen, W.M.A.: Fragmentation of toxicologically relevant drugs in positive-ion liquid chromatography-tandem mass spectrometry. Mass Spectrom. Rev. 30(4), 626-663 (2011)
    • (2011) Mass Spectrom. Rev. , vol.30 , Issue.4 , pp. 626-663
    • Niessen, W.M.A.1
  • 30
    • 78650739749 scopus 로고    scopus 로고
    • Building an empirical mass spectra library for screening of organic pollutants by ultra-high-pressure liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry
    • 10.1002/rcm.4860
    • Díaz, R.; Ibáñez, M.; Sancho, J.V.; Hernández, F.: Building an empirical mass spectra library for screening of organic pollutants by ultra-high-pressure liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. 25(2), 355-369 (2011)
    • (2011) Rapid Commun. Mass Spectrom. , vol.25 , Issue.2 , pp. 355-369
    • Díaz, R.1    Ibáñez, M.2    Sancho, J.V.3    Hernández, F.4
  • 31
    • 33746538415 scopus 로고    scopus 로고
    • Electrospray-ionization MS/MS library of drugs as database for method development and drug identification
    • 10.1016/j.forsciint.2006.02.053 1:CAS:528:DC%2BD28XotFWkt7Y%3D
    • Dresen, S.; Kempf, J.; Weinmann, W.: Electrospray-ionization MS/MS library of drugs as database for method development and drug identification. Forensic Sci. Int. 161(2/3), 86-91 (2006)
    • (2006) Forensic Sci. Int. , vol.161 , Issue.23 , pp. 86-91
    • Dresen, S.1    Kempf, J.2    Weinmann, W.3
  • 33
    • 84880806293 scopus 로고    scopus 로고
    • Accessed 19 Jan 2012
    • SciFinder. 2012. Available at: https://scifinder.cas.org/scifinder/view/ scifinder/scifinderExplore.jsf. Accessed 19 Jan 2012
    • (2012) SciFinder
  • 35
    • 84873054732 scopus 로고    scopus 로고
    • GenStat 14th ed. VSN International Ltd.: 2011, version 14.2.0.6297
    • GenStat 14th ed. VSN International Ltd.: 2011, version 14.2.0.6297
  • 36
    • 33750513356 scopus 로고    scopus 로고
    • Confirmation of organic micropollutants detected in environmental samples by liquid chromatography tandem mass spectrometry: Achievements and pitfalls
    • 10.1016/j.trac.2006.06.012 1:CAS:528:DC%2BD28XhtFyqsLnJ
    • Pozo, Ó.J.; Sancho, J.V.; Ibáñez, M.; Hernández, F.; Niessen, W.M.A.: Confirmation of organic micropollutants detected in environmental samples by liquid chromatography tandem mass spectrometry: Achievements and pitfalls. TrAC - Trend. Anal. Chem. 25(10), 1030-1042 (2006)
    • (2006) TrAC - Trend. Anal. Chem. , vol.25 , Issue.10 , pp. 1030-1042
    • Pozo, Ó.1    Sancho, J.V.2    Ibáñez, M.3    Hernández, F.4    Niessen, W.M.A.5
  • 37
    • 84985478030 scopus 로고
    • Probhability based matching of mass spectra
    • 10.1002/oms.1210090710 1:CAS:528:DyaE2MXmsl2isA%3D%3D
    • McLafferty, F.W.; Hertel, R.H.; Villwock, R.D.: Probhability based matching of mass spectra. Org. Mass. Spectrom. 9, 690-702 (1974)
    • (1974) Org. Mass. Spectrom. , vol.9 , pp. 690-702
    • McLafferty, F.W.1    Hertel, R.H.2    Villwock, R.D.3
  • 38
    • 0000212341 scopus 로고
    • Statistical occurrence of mass and abundance values in mass spectra
    • 10.1021/ac60357a050 1:CAS:528:DyaE2MXksFWrtLg%3D
    • Pesyna, G.M.; McLafferty, F.W.; Venkataraghavan, R.; Dayringer, H.E.: Statistical occurrence of mass and abundance values in mass spectra. Anal. Chem. 47(7), 1161-1164 (1975)
    • (1975) Anal. Chem. , vol.47 , Issue.7 , pp. 1161-1164
    • Pesyna, G.M.1    McLafferty, F.W.2    Venkataraghavan, R.3    Dayringer, H.E.4
  • 39
    • 0016985203 scopus 로고
    • Probability based matching system using a large collection of reference mass spectra
    • 10.1021/ac50003a026 1:CAS:528:DyaE28XkslWktrs%3D
    • Pesyna, G.M.; Venkataraghavan, R.; Dayringer, H.E.; McLAfferty, F.W.: Probability based matching system using a large collection of reference mass spectra. Anal. Chem. 48(9), 1362-1368 (1976)
    • (1976) Anal. Chem. , vol.48 , Issue.9 , pp. 1362-1368
    • Pesyna, G.M.1    Venkataraghavan, R.2    Dayringer, H.E.3    McLafferty, F.W.4
  • 40
    • 0009580116 scopus 로고
    • Specific and selective reactions
    • 10.1016/0039-9140(65)80021-2 1:CAS:528:DyaF2MXktVSiuw%3D%3D
    • Belcher, R.: Specific and selective reactions. Talanta 12(1), 129 (1965)
    • (1965) Talanta , vol.12 , Issue.1 , pp. 129
    • Belcher, R.1
  • 41
    • 0009598215 scopus 로고
    • Selectivity index
    • 10.1016/0039-9140(65)80022-4
    • Betteridge, D.: Selectivity index. Talanta 12(1), 129-131 (1965)
    • (1965) Talanta , vol.12 , Issue.1 , pp. 129-131
    • Betteridge, D.1
  • 42
    • 84873053100 scopus 로고    scopus 로고
    • Trends in sample preparation procedures for the analysis of veterinary drug residues in food products
    • unpublished (submitted)
    • Berendsen, B.J.A.; Stolker, A.A.M.; Nielen, M.W.F. Trends in sample preparation procedures for the analysis of veterinary drug residues in food products. TrAC - Trend. Anal. Chem. (2012) unpublished (submitted).
    • (2012) TrAC - Trend. Anal. Chem.
    • Berendsen, B.J.A.1    Stolker, A.A.M.2    Nielen, M.W.F.3
  • 43
    • 84856157713 scopus 로고    scopus 로고
    • Identification of "known Unknowns" utilizing accurate mass data and ChemSpider
    • 10.1007/s13361-011-0265-y 1:CAS:528:DC%2BC38XltVaitbw%3D
    • Little, J.L.; Williams, A.J.; Pshenichnov, A.; Tkachenko, V.: Identification of "Known Unknowns" utilizing accurate mass data and ChemSpider. J. Am. Soc. Mass Spectrom. 23, 179-185 (2012)
    • (2012) J. Am. Soc. Mass Spectrom. , vol.23 , pp. 179-185
    • Little, J.L.1    Williams, A.J.2    Pshenichnov, A.3    Tkachenko, V.4
  • 44
    • 84870406405 scopus 로고    scopus 로고
    • PubChem: Integrated Platform of Small Molecules and Biological Activities
    • R.A. Wheeler and D.C. Spellmeyer (Eds.) Washington, DC
    • Bolton, E.; Wang, Y.; Thiessen, P.A.; Bryant, S.H. PubChem: Integrated Platform of Small Molecules and Biological Activities. In: R.A. Wheeler and D.C. Spellmeyer (Eds.), American Chemical Society: Washington, DC, 2008.
    • (2008) American Chemical Society
    • Bolton, E.1    Wang, Y.2    Thiessen, P.A.3    Bryant, S.H.4
  • 45
    • 34247163207 scopus 로고    scopus 로고
    • Seven golden rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
    • Kind, T.: Fiehn, O. Seven golden rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry. BMC Bioinformatics 8, 105 (2007)
    • (2007) BMC Bioinformatics , vol.8 , pp. 105
    • Kind, T.1    Fiehn, O.2
  • 47
    • 35148845632 scopus 로고    scopus 로고
    • Review on modeling aspects in reversed-phase liquid chromatographic quantitative structure-retention relationships
    • 10.1016/j.aca.2007.09.014 1:CAS:528:DC%2BD2sXhtFOjur%2FI
    • Put, R.; Vander Heyden, Y.: Review on modeling aspects in reversed-phase liquid chromatographic quantitative structure-retention relationships. Anal. Chim. Acta 602(2), 164-172 (2007)
    • (2007) Anal. Chim. Acta , vol.602 , Issue.2 , pp. 164-172
    • Put, R.1    Vander Heyden, Y.2
  • 48
    • 33747622807 scopus 로고    scopus 로고
    • Prediction of retention of nucleic compounds based on a qspr model
    • 10.1365/s10337-006-0840-8
    • Zheng, J.; Polyakova, Y.; Row, K.: Prediction of retention of nucleic compounds based on a qspr model. Chromatographia 64(3), 1-9 (2006)
    • (2006) Chromatographia , vol.64 , Issue.3 , pp. 1-9
    • Zheng, J.1    Polyakova, Y.2    Row, K.3
  • 49
    • 0037435994 scopus 로고    scopus 로고
    • Predictive approaches to gradient retention based on analyte structural descriptors from calculation chemistry
    • Baçzek, T.; Kaliszan, R.: Predictive approaches to gradient retention based on analyte structural descriptors from calculation chemistry. J. Chromatogr. A 987(1/2), 29-37 (2003)
    • (2003) J. Chromatogr. A , vol.987 , Issue.12 , pp. 29-37
    • Baçzek, T.1    Kaliszan, R.2
  • 50
    • 60549087732 scopus 로고    scopus 로고
    • QSRR Prediction of the chromatographic retention behavior of painkiller drugs
    • 1:CAS:528:DC%2BD1MXhslyjtLw%3D
    • Ghasemi, J.; Saaidpour, S.: QSRR Prediction of the chromatographic retention behavior of painkiller drugs. J. Chromatogr. Sci. 47(2), 156-163 (2009)
    • (2009) J. Chromatogr. Sci. , vol.47 , Issue.2 , pp. 156-163
    • Ghasemi, J.1    Saaidpour, S.2
  • 52
    • 0038150530 scopus 로고    scopus 로고
    • God's signature: DNA profiling, the new gold standard in forensic science
    • 10.1016/S0160-9327(03)00068-1 1:CAS:528:DC%2BD3sXktlyrsbw%3D
    • Lynch, M.: God's signature: DNA profiling, the new gold standard in forensic science. Endeavour 27(2), 93-97 (2003)
    • (2003) Endeavour , vol.27 , Issue.2 , pp. 93-97
    • Lynch, M.1
  • 53
    • 43649084642 scopus 로고    scopus 로고
    • Confirmatory analysis of trenbolone using accurate mass measurement with LC/TOF-MS
    • 10.1016/j.aca.2008.04.040 1:CAS:528:DC%2BD1cXmtlemtrc%3D
    • Blokland, M.H.; Zoontjes, P.W.; Sterk, S.S.; Stephany, R.W.; Zweigenbaum, J.; van Ginkel, L.A.: Confirmatory analysis of trenbolone using accurate mass measurement with LC/TOF-MS. Anal. Chim. Acta 618(1), 86-93 (2008)
    • (2008) Anal. Chim. Acta , vol.618 , Issue.1 , pp. 86-93
    • Blokland, M.H.1    Zoontjes, P.W.2    Sterk, S.S.3    Stephany, R.W.4    Zweigenbaum, J.5    Van Ginkel, L.A.6
  • 54
    • 84857429633 scopus 로고    scopus 로고
    • Assessment of liquid chromatography-tandem mass spectrometry approaches for the analysis of ceftiofur metabolites in poultry muscle
    • 10.1080/19440049.2011.635348
    • Berendsen, B.J.A.; Stolker, L.A.M.; Nielen, M.W.F.: Assessment of liquid chromatography-tandem mass spectrometry approaches for the analysis of ceftiofur metabolites in poultry muscle. Food Add. Contam. A 29(2), 197-207 (2011)
    • (2011) Food Add. Contam. A , vol.29 , Issue.2 , pp. 197-207
    • Berendsen, B.J.A.1    Stolker, L.A.M.2    Nielen, M.W.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.