Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting

Stem Cell Research and Therapy

Volumn 3, Issue 6, 2012, Pages

  Reekmans, Kristien ^a   De Vocht, Nathalie ^a   Praet, Jelle ^a   Fransen, Erik ^a   Le Blon, Debbie ^a   Hoornaert, Chloé ^a   Daans, Jasmijn ^a   Goossens, Herman ^a   Van Der Linden, Annemie ^a   Berneman, Zwi ^a   Ponsaerts, Peter ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; AUTOPSY; BIOLUMINESCENCE; BRAIN TISSUE; CELL DAMAGE; CELL DENSITY; CELL FUNCTION; CELL LOSS; CELL SURVIVAL; CELLULAR DISTRIBUTION; FEMALE; GRAFT FAILURE; GRAFT SURVIVAL; HISTOPATHOLOGY; HYPOXIC CELL; IMMUNOMODULATION; IN VIVO STUDY; INNATE IMMUNITY; MACROGLIA; MICROGLIA; MOUSE; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCAR FORMATION; SPATIOTEMPORAL ANALYSIS; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; NEURAL STEM CELL; PATHOLOGY; TRANSPLANTATION;

GREEN FLUORESCENT PROTEIN;

ANIMALS; BRAIN; CELL SURVIVAL; CELLS, CULTURED; GRAFT SURVIVAL; GREEN FLUORESCENT PROTEINS; IMMUNITY, INNATE; MICE; NEURAL STEM CELLS; SPATIO-TEMPORAL ANALYSIS;

EID: 84873028290     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt147     Document Type: Article

References (24)

1. Current challenges for the advancement of neural stem cell biology and transplantation research. Reekmans K, Praet J, Daans J, Reumers V, Pauwels P, Van der Linden A, Berneman ZN, Ponsaerts P, Stem Cell Rev 2012 8 262 278 10.1007/s12015-011-9266-2 21537994
2. Stem cell therapy for multiple sclerosis: preclinical evidence beyond all doubt? Reekmans K, Praet J, De Vocht N, Daans J, Van der Linden A, Berneman Z, Ponsaerts P, Regen Med 2012 7 245 259 10.2217/rme.12.5 22397612
3. Neural tissue engineering using embryonic and induced pluripotent stem cells. Willerth SM, Stem Cell Res Ther 2011 2 17 10.1186/scrt58 21539726
4. Stem cell challenges in the treatment of neurodegenerative disease. Feng Z, Gao F, CNS Neurosci Ther 2012 18 142 148 10.1111/j.1755-5949.2011.00239.x 22070610
5. Can cell therapy heal a spinal cord injury? Ronsyn MW, Berneman ZN, Van Tendeloo VF, Jorens PG, Ponsaerts P, Spinal Cord 2008 46 532 539 10.1038/sc.2008.13 18347607
6. Clinical translation of cell transplantation in the brain. Dunnett SB, Rosser AE, Curr Opin Organ Transplant 2011 16 632 639 10.1097/MOT. 0b013e32834c2356 21926621
7. Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells. Martino G, Pluchino S, Bonfanti L, Schwartz M, Physiol Rev 2011 91 1281 1304 10.1152/physrev.00032.2010 22013212
8. Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model. Sher F, van Dam G, Boddeke E, Copray S, Stem Cells 2009 27 1582 1591 10.1002/stem.76 19544465
9. Cell type-associated differences in migration, survival and immunogenicity following grafting in CNS tissue. Praet J, Reekmans K, Lin D, De Vocht N, Bergwerf I, Tambuyzer B, Daans J, Hens N, Goossens H, Pauwels P, Berneman Z, Van der Linden A, Ponsaerts P, Cell Transplant 2012
10. Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice? Reekmans KP, Praet J, De Vocht N, Tambuyzer BR, Bergwerf I, Daans J, Baekelandt V, Vanhoutte G, Goossens H, Jorens PG, Ysebaert DK, Chatterjee S, Pauwels P, Van Marck E, Berneman ZN, Van der Linden A, Ponsaerts P, Cell Transplant 2011 20 851 869 10.3727/096368910X543411 21092405
11. Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice. Bergwerf I, De Vocht N, Tambuyzer B, Verschueren J, Reekmans K, Daans J, Ibrahimi A, Van Tendeloo V, Chatterjee S, Goossens H, Jorens PG, Baekelandt V, Ysebaert D, Van Marck E, Berneman ZN, Linden AV, Ponsaerts P, BMC Biotechnol 2009 9 1 10.1186/1472-6750-9-1 19128466
12. Labeling of Luciferase/eGFP-expressing bone marrow-derived stromal cells with fluorescent micron-sized iron oxide particles improves quantitative and qualitative multimodal imaging of cellular grafts in vivo. De Vocht N, Bergwerf I, Vanhoutte G, Daans J, De Visscher G, Chatterjee S, Pauwels P, Berneman Z, Ponsaerts P, Van der Linden A, Mol Imaging Biol 2011 13 1133 1145 10.1007/s11307-011-0469-3 21246293
13. Intravenous neural stem cells abolish nociceptive hypersensitivity and trigger nerve regeneration in experimental neuropathy. Franchi S, Valsecchi AE, Borsani E, Procacci P, Ferrari D, Zalfa C, Sartori P, Rodella LF, Vescovi A, Maione S, Rossi F, Sacerdote P, Colleoni M, Panerai AE, Pain 2012 153 850 861 10.1016/j.pain.2012.01.008 22321918
14. Intrathecal transplantation of stem cells by lumbar puncture for thoracic spinal cord injury in the rat. Mothe AJ, Bozkurt G, Catapano J, Zabojova J, Wang X, Keating A, Tator CH, Spinal Cord 2011 49 967 973 10.1038/sc.2011.46 21606931
15. ICV-transplanted human glial precursor cells are short-lived yet exert immunomodulatory effects in mice with EAE. Kim H, Walczak P, Muja N, Campanelli JT, Bulte JW, Glia 2012 60 1117 1129 10.1002/glia.22339 22499166
16. Matrigel supports survival and neuronal differentiation of grafted embryonic stem cell-derived neural precursor cells. Uemura M, Refaat MM, Shinoyama M, Hayashi H, Hashimoto N, Takahashi J, J Neurosci Res 2010 88 542 551 19774667
17. Hydrogel matrix to support stem cell survival after brain transplantation in stroke. Zhong J, Chan A, Morad L, Kornblum HI, Fan G, Carmichael ST, Neurorehabil Neural Repair 2010 24 636 644 10.1177/1545968310361958 20424193
18. Creating permissive microenvironments for stem cell transplantation into the central nervous system. Kim H, Cooke MJ, Shoichet MS, Trends Biotechnol 2012 30 55 63 10.1016/j.tibtech.2011.07.002 21831464
19. The yin and yang of microglia. Czeh M, Gressens P, Kaindl AM, Dev Neurosci 2011 33 199 209 10.1159/000328989 21757877
20. Glia: an emerging target for neurological disease therapy. Almad AA, Maragakis NJ, Stem Cell Res Ther 2012 3 37 10.1186/scrt128 23021042
21. Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain. De Vocht N, Lin D, Praet J, Hoornaert C, Reekmans K, Le Blon D, Daans J, Pauwels P, Goossens H, Hens N, Berneman Z, Van der Linden A, Ponsaerts P, Immunobiology 2012
22. Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells. Nakanishi M, Niidome T, Matsuda S, Akaike A, Kihara T, Sugimoto H, Eur J Neurosci 2007 25 649 658 10.1111/j.1460-9568.2007.05309.x 17328769
23. Reactive astrogliosis induces astrocytic differentiation of adult neural stem/progenitor cells in vitro. Faijerson J, Tinsley RB, Aprico K, Thorsell A, Nodin C, Nilsson M, Blomstrand F, Eriksson PS, J Neurosci Res 2006 84 1415 1424 10.1002/jnr.21044 16998910 (Pubitemid 44683136)
24. Anti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice. Worlitzer MM, Bunk EC, Hemmer K, Schwamborn JC, Stem Cell Res Ther 2012 3 33 10.1186/scrt124 22892385