Altering SARS coronavirus frameshift efficiency affects genomic and subgenomic RNA production

Viruses

Volumn 5, Issue 1, 2013, Pages 279-294

  Plant, Ewan P ^a   Sims, Amy C ^b   Baric, Ralph S ^b,c   Dinman, Jonathan D ^d   Taylor, Deborah R ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b The University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d University of Maryland   (United States)

Author keywords

Pseudoknot; Ribosomal frameshifting; SARS; Severe acute respiratory syndrome; Viral replication

Indexed keywords

VIRUS PROTEIN; VIRUS RNA;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BASE PAIRING; CODON; CONTROLLED STUDY; GENETIC VARIABILITY; MUTATIONAL ANALYSIS; NONHUMAN; OPEN READING FRAME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBOSOMAL FRAMESHIFTING; RNA EXTRACTION; RNA SEQUENCE; RNA SYNTHESIS; SARS CORONAVIRUS; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS VIABILITY;

FRAMESHIFT MUTATION; FRAMESHIFTING, RIBOSOMAL; GENOME, VIRAL; HUMANS; RNA, VIRAL; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRAL PROTEINS; VIRUS REPLICATION;

SARS CORONAVIRUS;

EID: 84872868791     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v5010279     Document Type: Article

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