Fertility in male patients with seronegative spondyloarthropathies treated with infliximab

Joint Bone Spine

Volumn 80, Issue 1, 2013, Pages 34-37

  Saougou, Ioanna ^a   Markatseli, Theodora E ^a   Papagoras, Charalampos ^a   Kaltsonoudis, Evripidis ^a   Voulgari, Paraskevi V ^a   Drosos, Alexandros A ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

Author keywords

Ankylosing spondylitis; Infliximab; Male fertility; Psoriatic arthritis; Spondyloarthropathies

Indexed keywords

CYCLOSPORIN A; INFLIXIMAB; MEPREDNISONE; METHOTREXATE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONGENITAL DISORDER; FIRST TRIMESTER PREGNANCY; FOLLOW UP; HUMAN; HYDROCEPHALUS; MALE; MALE FERTILITY; OUTPATIENT; PSORIATIC ARTHRITIS; RHEUMATOLOGY; SPONDYLOARTHROPATHY;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES, MONOCLONAL; HUMANS; INFERTILITY, MALE; MALE; SPERMATOGENESIS; SPONDYLARTHROPATHIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84872852150     PISSN: 1297319X     EISSN: 17787254     Source Type: Journal    
DOI: 10.1016/j.jbspin.2012.03.004     Document Type: Article

References (38)

1. Carbone L.D., Cooper C., Michet C.J., et al. Ankylosing spondylitis in Rochester, Minnesota, 1935-1989. Is the epidemiology changing?. Arthritis Rheum 1992, 35:1476-1482.
2. Boyer G.S., Lanier A.P., Templin D.W. Prevalence rates of spondyloarthropathies, rheumatoid arthritis, and other rheumatic disorders in an Alaskan Inupiat Eskimo population. J Rheumatol 1988, 15:678-683.
3. Carter E.T., McKenna C.H., Brian D.D., et al. Epidemiology of Ankylosing spondylitis in Rochester, Minnesota, 1935-1973. Arthritis Rheum 1979, 22:365-370.
4. Gran J.T., Husby G., Hordvik M. Prevalence of ankylosing spondylitis in males and females in a young middle-aged population of Tromsø, northern Norway. Ann Rheum Dis 1985, 44:359-367.
5. Wilson F.C., Icen M., Crowson C.S., et al. Time trends in epidemiology and characteristics of psoriatic arthritis over 3 decades: a population-based study. J Rheumatol 2009, 36:361-367.
6. Alamanos Y., Voulgari P.V., Drosos A.A. Incidence and prevalence of psoriatic arthritis: a systematic review. J Rheumatol 2008, 35:1354-1358.
7. Setty A.R., Choi H.K. Psoriatic arthritis epidemiology. Curr Rheumatol Rep 2007, 9:449-454.
8. Gordon D., Beastall G.H., Thomson J.A., et al. Androgenic status and sexual function in males with rheumatoid arthritis and ankylosing spondylitis. Q J Med 1986, 60:671-679.
9. Tapia-Serrano R., Jimenez-Balderas F.J., Murrieta S., et al. Testicular function in active ankylosing spondylitis. Therapeutic response to human chorionic gonadotrophin. J Rheumatol 1991, 18:841-848.
10. Guzick D.S., Overstreet J.W., Factor-Litvak P., et al. Sperm morphology, motility, and concentration in fertile and infertile men. N Engl J Med 2001, 345:1388-1393.
11. Pentikäinen V., Erkkilä K., Suomalainen L., et al. TNFalpha down-regulates the Fas ligand and inhibits germ cell apoptosis in the human testis. J Clin Endocrinol Metab 2001, 86:4480-4488.
12. Said T.M., Agarwal A., Falcone T., et al. Infliximab may reverse the toxic effects induced by tumor necrosis factor alpha in human spermatozoa: an in vitro model. Fertil Steril 2005, 83:1665-1673.
13. Saougou I., Markatseli T.E., Voulgari P.V., et al. Maintained clinical response of infliximab treatment in ankylosing spondylitis: a 6-year long-term study. Joint Bone Spine 2010, 77:325-329.
14. Saougou I., Markatseli T.E., Papagoras C., et al. Sustained clinical response in psoriatic arthritis patients treated with anti-TNF agents: a 5-year open-label observational cohort study. Semin Arthritis Rheum 2011, 40:398-406.
15. Voulgari P.V., Alamanos Y., Nikas S.N., et al. Infliximab therapy in established rheumatoid arthritis: an observational study. Am J Med 2005, 118:515-520.
16. Katz J.A., Antoni C., Keenan G.F., et al. Outcome of pregnancy in women receiving infliximab for the treatment of Crohn's disease and rheumatoid arthritis. Am J Gastroenterol 2004, 99:2385-2392.
17. Lin J., Ziring D., Desai S., et al. TNFalpha blockade in human diseases: an overview of efficacy and safety. Clin Immunol 2008, 126:13-30.
18. Osting V.C., Carter J.D. A safety assessment of tumor necrosis factor antagonists during pregnancy. Expert Opin Drug Saf 2010, 9:421-429.
19. Mahadevan U., Terdiman J.P., Aron J., et al. Infliximab and semen quality in men with inflammatory bowel disease. Inflamm Bowel Dis 2005, 11:395-399.
20. Paschou S., Voulgari P.V., Vrabie I.G., et al. Fertility and reproduction in male patients with ankylosing spondylitis treated with infliximab. J Rheumatol 2009, 36:351-354.
21. van der Linden S., Valkenburg H.A., Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984, 27:361-368.
22. Dougados M., van der Linden S., Juhlin R., et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 1991, 34:1218-1227.
23. Estrada L.S., Champion H.C., Wang R., et al. Effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human sperm motility, viability and motion parameters. Int J Androl 1997, 20:237-242.
24. Perdichizzi A., Nicoletti F., La Vignera S., et al. Effects of tumour necrosis factor-alpha on human sperm motility and apoptosis. J Clin Immunol 2007, 27:152-162.
25. Clark D.A. Anti-TNFalpha therapy in immune-mediated subfertility: state of the art. J Reprod Immunol 2010, 85:15-24.
26. Treacy G. Using an analogous monoclonal antibody to evaluate the reproductive and chronic toxicity potential for a humanized anti-TNFalpha monoclonal antibody. Hum Exp Toxicol 2000, 19:226-228.
27. Suominen J.S., Wang Y., Kaipia A., et al. Tumor necrosis factor-alpha (TNF-alpha) promotes cell survival during spermatogenesis, and this effect can be blocked by infliximab, a TNF-alpha antagonist. Eur J Endocrinol 2004, 151:629-640.
28. La Montagna G., Malesci D., Buono R., et al. Does infliximab cause spermatogenesis alterations?. Arthritis Rheum 2005, 52:S216.
29. Ponchietti A., Erre G.L., Fenu P., et al. Effect of TNF-alpha blockers on sperm count and motility in patients with rheumatic diseases: a cross-sectional study. Ann Rheum Dis 2009, 68:229.
30. Villiger P.M., Caliezi G., Cottin V., et al. Effects of TNF antagonists on sperm characteristics in patients with spondyloarthritis. Ann Rheum Dis 2010, 69:1842-1844.
31. Lichtenstein G.R., Feagan B.G., Cohen R.D., et al. Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry. Clin Gastroenterol Hepatol 2006, 4:621-630.
32. Verstappen S.M.M., King Y., Watson K.D., et al. Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register. Ann Rheum Dis 2011, 70:823-826.
33. Hyrich K.L., Symmons D.P., Watson K.D., et al. British Society, for Rheumatology Biologics Register. Pregnancy outcome in women who were exposed to anti-tumor necrosis factor agents: results from a national population register. Arthritis Rheum 2006, 54:2701-2702.
34. Onose G., Pereţianu D., Zaharescu J., et al. Correlations between spondylarthropathic inflammatory troubles and gonadal (androgenic) troubles in men. Study on 30 cases with a new methodological analysis. Rom J Intern Med 1995, 33:93-111.
35. Sato A., Naganuma M., Asakura K., et al. Conception outcomes and opinions about pregnancy for men with inflammatory bowel disease. J Crohns Colitis 2010, 4:183-188.
36. Beghin D., Cournot M.P., Vauzelle C., et al. Paternal exposure to methotrexate and pregnancy outcomes. J Rheumatol 2011, 38:628-632.
37. Visser K., Katchamart W., Loza E., et al. Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative. Ann Rheum Dis 2009, 68:1086-1093.
38. Ajala T., Rafi J., Larsen-Disney P., et al. Fertility preservation for cancer patients: a review. Obstet Gynecol Int 2010, 2010:160386.