Dickkopf-1 as a Novel Predictor Is Associated with Risk Stratification by GRACE Risk Scores for Predictive Value in Patients with Acute Coronary Syndrome: A Retrospective Research

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Wang, Lin ^a   Hu, Xiao Bo ^a,b   Zhang, Wei ^a   Wu, Lin Di ^a   Liu, Yu Sheng ^a,c   Hu, Bo ^a,b   Bi, Cheng Long ^a   Chen, Yi Fei ^a   Liu, Xin Xin ^a   Ge, Cheng ^a   Zhang, Yun ^a   Zhang, Mei ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^c THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; DICKKOPF 1 PROTEIN;

ACUTE CORONARY SYNDROME; ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CORONARY RISK; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PREDICTIVE VALUE; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION;

ACUTE CORONARY SYNDROME; AGED; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK ASSESSMENT;

EID: 84872850232     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054731     Document Type: Article

References (28)

1. Shishehbor MH, Bhatt DL, (2004) Inflammation and atherosclerosis. Curr Atheroscler Rep 6: 131-139.
2. Libby P, Ridker PM, Maseri A, (2002) Inflammation and atherosclerosis. Circulation 105: 1135-1143.
3. Morrow DA, de Lemos JA, Sabatine MS, Wiviott SD, Blazing MA, et al. (2006) Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial. Circulation 114: 281-288.
4. Kim J, Kim J, Kim DW, Ha Y, Ihm MH, et al. (2010) Wnt5a induces endothelial inflammation via beta-catenin-independent signaling. J Immunol 185: 1274-1282.
5. Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, et al. (2009) Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Arterioscler Thromb Vasc Biol 29: 1228-1234.
6. Wang SY, Liu YY, Ye H, Guo JP, Li R, et al. (2011) Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis. J Rheumatol 38: 821-827.
7. Gomceli I, Bostanci EB, Ozer I, Kemik AS, Turhan N, et al. (2012) A Novel Screening Biomarker in Gastric Cancer: Serum Dickkopf-1. Hepatogastroenterology 59: 1661-1664.
8. Lane NE, Nevitt MC, Lui LY, de Leon P, Corr M, et al. (2007) Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women. Arthritis Rheum 56: 3319-3325.
9. Gui T, Shimokado A, Sun Y, Akasaka T, Muragaki Y, (2012) Diverse roles of macrophages in atherosclerosis: from inflammatory biology to biomarker discovery. Mediators Inflamm 2012: 693083.
10. Siasos G, Tousoulis D, Kioufis S, Oikonomou E, Siasou Z, et al. (2012) Inflammatory mechanisms in atherosclerosis: the impact of matrix metalloproteinases. Curr Top Med Chem 12: 1132-1148.
11. Trepels T, Zeiher AM, Fichtlscherer S, (2004) Acute coronary syndrome and inflammation. Biomarkers for diagnostics and risk stratification. Herz 29: 769-776.
12. Hamm CW, Nef HM, Rolf A, Möllmann H, (2011) Calcium and C-reactive protein hot enough to predict the future? J Am Coll Cardiol 57: 1465-1467.
13. Eagle KA, Lim MJ, Dabbous OH, Pieper KS, Goldberg RJ, et al. (2004) A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry. JAMA 291: 2727-2733.
14. Abu-Assi E, García-Acuña JM, Peña-Gil C, González-Juanatey JR, (2010) Validation of the GRACE risk score for predicting death within 6 months of follow-up in a contemporary cohort of patients with acute coronary syndrome. Rev Esp Cardiol 63: 640-648.
15. Ziegler A, Kastner C, Blettner M, (1998) The generalised estimating equations: An annotated bibliography. Biometric J 40: 115-139.
16. Möhlenkamp S, Lehmann N, Moebus S, Schmermund A, Dragano N, et al. (2011) Quantification of coronary atherosclerosis and inflammation to predict coronary events and all-cause mortality. J Am Coll Cardiol 57: 1455-1464.
17. Yang Y, (2012) Wnt signaling in development and disease. Cell Biosci 2: 14.
18. Mastroiacovo F, Busceti CL, Biagioni F, Moyanova SG, Meisler MH, et al. (2009) Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia. J Cereb Blood Flow Metab 29: 264-276.
19. Goliasch G, Wiesbauer F, Kastl SP, Katsaros KM, Blessberger H, et al. (2012) Premature myocardial infarction is associated with low serum levels of Wnt-1. Atherosclerosis 222: 251-256.
20. Seifert-Held T, Pekar T, Gattringer T, Simmet NE, Scharnagl H, et al. (2011) Circulating Dickkopf-1 in acute ischemic stroke and clinically stable cerebrovascular disease. Atherosclerosis 218: 233-237.
21. Schiele F, Meneveau N, Seronde MF, Chopard R, Descotes-Genon V, et al. (2010) C-reactive protein improves risk prediction in patients with acute coronary syndromes. Eur Heart J 31: 290-297.
22. Nakamura M, Yamashita T, Yajima J, Oikawa Y, Ogasawara K, et al. (2010) Clinical outcome after acute coronary syndrome in Japanese patients: an observational cohort study. J Cardiol 55: 69-76.
23. Granger CB, Goldberg RJ, Dabbous O, Pieper KS, Eagle KA, et al. (2003) Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med 163: 2345-2353.
24. D'Ascenzo F, Biondi-Zoccai G, Moretti C, Bollati M, Omedè P, et al. (2012) TIMI, GRACE and alternative risk scores in Acute Coronary Syndromes: a meta-analysis of 40 derivation studies on 216,552 patients and of 42 validation studies on 31,625 patients. Contemp Clin Trials 33: 507-514.
25. Meune C, Drexler B, Haaf P, Reichlin T, Reiter M, et al. (2011) The GRACE score's performance in predicting in-hospital and 1-year outcome in the era of high-sensitivity cardiac troponin assays and B-type natriuretic peptide. Heart 97: 1479-1483.
26. Eggers KM, Kempf T, Venge P, Wallentin L, Wollert KC, et al. (2010) Improving long-term risk prediction in patients with acute chest pain: the Global Registry of Acute Coronary Events (GRACE) risk score is enhanced by selected nonnecrosis biomarkers. Am Heart J 160: 88-94.
27. Tang EW, Wong CK, Herbison P, (2007) Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart J 153: 29-35.
28. Beygui F, Silvain J, Pena A, Bellemain-Appaix A, Collet JP, et al. (2010) Usefulness of biomarker strategy to improve GRACE score's prediction performance in patients with non-ST-segment elevation acute coronary syndrome and low event rates. Am J Cardiol 106: 650-658.