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Volumn 34, Issue 1, 2013, Pages 285-291

Cucurbitacin D induces growth inhibition, cell cycle arrest, and apoptosis in human endometrial and ovarian cancer cells

Author keywords

Apoptosis; Cell cycle; Cucurbitacin D; Endometrial cancer; Ovarian cancer

Indexed keywords

CASPASE 3; CASPASE 9; CUCURBITACIN GLYCOSIDE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; PROCASPASE 9; PROTEIN BAD; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1;

EID: 84872801614     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-012-0549-2     Document Type: Article
Times cited : (30)

References (18)
  • 1
    • 38449099678 scopus 로고    scopus 로고
    • Gynecologic tumors
    • 18019623 10.1007/978-3-540-31203-1-11 1:STN:280:DC%2BD2snos1Khuw%3D%3D
    • MJ Reinhardt 2008 Gynecologic tumors Recent Results Cancer Res 170 141 150 18019623 10.1007/978-3-540-31203-1-11 1:STN:280:DC%2BD2snos1Khuw%3D%3D
    • (2008) Recent Results Cancer Res , vol.170 , pp. 141-150
    • Reinhardt, M.J.1
  • 3
    • 37849025830 scopus 로고    scopus 로고
    • Tumor residual after surgical cytoreduction in prediction of clinical outcome in stage IV epithelial ovarian cancer: A gynecologic oncology group study
    • 10.1200/JCO.2007.13.1953 18025437 10.1200/JCO.2007.13.1953
    • WE Winter 3rd GL Maxwell C Tian, et al. 2008 Tumor residual after surgical cytoreduction in prediction of clinical outcome in stage IV epithelial ovarian cancer: a gynecologic oncology group study J Clin Oncol 26 83 89 10.1200/JCO.2007.13.1953 18025437 10.1200/JCO.2007.13.1953
    • (2008) J Clin Oncol , vol.26 , pp. 83-89
    • Winter III, W.E.1    Maxwell, G.L.2    Tian, C.3
  • 4
    • 0037427563 scopus 로고    scopus 로고
    • Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana
    • 12445672 10.1016/S0304-3835(02)00497-4 1:CAS:528:DC%2BD38XoslGis7s%3D
    • B Jayaprakasam NP Seeram MG Nair 2003 Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana Cancer Lett 189 11 16 12445672 10.1016/S0304-3835(02)00497-4 1:CAS:528:DC%2BD38XoslGis7s%3D
    • (2003) Cancer Lett , vol.189 , pp. 11-16
    • Jayaprakasam, B.1    Seeram, N.P.2    Nair, M.G.3
  • 5
    • 21244470815 scopus 로고    scopus 로고
    • Cucurbitacins and cucurbitane glycosides: Structures and biological activities
    • 10.1039/B418841C 16010347 10.1039/b418841c 1:CAS:528:DC%2BD2MXmtVaku7c%3D
    • JC Chen MH Chiu RL Nie, et al. 2005 Cucurbitacins and cucurbitane glycosides: structures and biological activities Nat Prod Rep 22 386 399 10.1039/B418841C 16010347 10.1039/b418841c 1:CAS:528:DC%2BD2MXmtVaku7c%3D
    • (2005) Nat Prod Rep , vol.22 , pp. 386-399
    • Chen, J.C.1    Chiu, M.H.2    Nie, R.L.3
  • 6
    • 61649114173 scopus 로고    scopus 로고
    • Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro
    • 19185617 10.1016/j.intimp.2009.01.006 1:CAS:528:DC%2BD1MXjt1Snsb4%3D
    • N Takahashi Y Yoshida T Sugiura, et al. 2009 Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro Int Immunopharmacol 9 508 513 19185617 10.1016/j.intimp.2009.01. 006 1:CAS:528:DC%2BD1MXjt1Snsb4%3D
    • (2009) Int Immunopharmacol , vol.9 , pp. 508-513
    • Takahashi, N.1    Yoshida, Y.2    Sugiura, T.3
  • 7
    • 79958786749 scopus 로고    scopus 로고
    • Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia
    • 10.1002/cncr.25711 21656752 10.1002/cncr.25711 1:CAS:528: DC%2BC3MXnt1KrtrY%3D
    • N Ding U Yamashita H Matsuoka, et al. 2011 Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia Cancer 117 2735 2746 10.1002/cncr.25711 21656752 10.1002/cncr.25711 1:CAS:528:DC%2BC3MXnt1KrtrY%3D
    • (2011) Cancer , vol.117 , pp. 2735-2746
    • Ding, N.1    Yamashita, U.2    Matsuoka, H.3
  • 8
    • 0031007673 scopus 로고    scopus 로고
    • Increased surface phosphatidylserine is an early marker of neuronal apoptosis
    • 10.1002/(SICI)1097-4547 9210526 10.1002/(SICI)1097-4547(19970615)48: 6<563::AID-JNR9>3.0.CO;2-8 1:CAS:528:DyaK2sXkt1eksbo%3D
    • G Rimon CE Bazenet KL Philpott, et al. 1997 Increased surface phosphatidylserine is an early marker of neuronal apoptosis J Neurosci Res 48 563 570 10.1002/(SICI)1097-4547 9210526 10.1002/(SICI)1097-4547(19970615)48: 6<563::AID-JNR9>3.0.CO;2-8 1:CAS:528:DyaK2sXkt1eksbo%3D
    • (1997) J Neurosci Res , vol.48 , pp. 563-570
    • Rimon, G.1    Bazenet, C.E.2    Philpott, K.L.3
  • 9
    • 0035418231 scopus 로고    scopus 로고
    • Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells
    • 11522638 1:CAS:528:DC%2BD3MXmsF2jsb4%3D
    • Y Chen DL Kramer P Diegelman, et al. 2001 Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells Cancer Res 61 6437 6444 11522638 1:CAS:528:DC%2BD3MXmsF2jsb4%3D
    • (2001) Cancer Res , vol.61 , pp. 6437-6444
    • Chen, Y.1    Kramer, D.L.2    Diegelman, P.3
  • 10
    • 47149085982 scopus 로고    scopus 로고
    • P21 and p27: Roles in carcinogenesis and drug resistance
    • 18590585 10.1017/S1462399408000744
    • AM Abukhdeir BH Park 2008 P21 and p27: roles in carcinogenesis and drug resistance Expert Rev Mol Med 10 e19 18590585 10.1017/S1462399408000744
    • (2008) Expert Rev Mol Med , vol.10 , pp. 19
    • Abukhdeir, A.M.1    Park, B.H.2
  • 11
    • 80051761743 scopus 로고    scopus 로고
    • The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
    • 10.1038/cdd.2011.17 21415859 10.1038/cdd.2011.17 1:CAS:528: DC%2BC3MXhtVWnt7rJ
    • PN Kelly A Strasser 2011 The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy Cell Death Differ 18 1414 1424 10.1038/cdd.2011.17 21415859 10.1038/cdd.2011.17 1:CAS:528:DC%2BC3MXhtVWnt7rJ
    • (2011) Cell Death Differ , vol.18 , pp. 1414-1424
    • Kelly, P.N.1    Strasser, A.2
  • 12
    • 0032924467 scopus 로고    scopus 로고
    • Cyclins and cell cycle checkpoints
    • 10.1146/annurev.pharmtox.39.1.295 1:CAS:528:DyaK1MXjtVejtL8%3D
    • DG Johnson CL Walker 1999 Cyclins and cell cycle checkpoints Ann Rev Pharmacol Toxicol 39 295 312 10.1146/annurev.pharmtox.39.1.295 1:CAS:528:DyaK1MXjtVejtL8%3D
    • (1999) Ann Rev Pharmacol Toxicol , vol.39 , pp. 295-312
    • Johnson, D.G.1    Walker, C.L.2
  • 13
    • 38049132680 scopus 로고    scopus 로고
    • Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9
    • 17955373 10.1007/s10495-007-0150-0 1:CAS:528:DC%2BD1cXjt12gsr0%3D
    • I Tretiakova D Blaesius L Maxia, et al. 2008 Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9 Apoptosis 13 119 131 17955373 10.1007/s10495-007-0150-0 1:CAS:528:DC%2BD1cXjt12gsr0%3D
    • (2008) Apoptosis , vol.13 , pp. 119-131
    • Tretiakova, I.1    Blaesius, D.2    Maxia, L.3
  • 14
    • 78649450333 scopus 로고    scopus 로고
    • Cucurbitacin D induces fetal hemoglobin synthesis in K562 cells and human hematopoietic progenitors through activation of p38 pathway and stabilization of the γ-globin mRNA
    • 10.1016/j.bcmd.2010.09.004 20926322 10.1016/j.bcmd.2010.09.004 1:CAS:528:DC%2BC3cXhsV2jtLrL
    • K Liu H Xing S Xhang, et al. 2010 Cucurbitacin D induces fetal hemoglobin synthesis in K562 cells and human hematopoietic progenitors through activation of p38 pathway and stabilization of the γ-globin mRNA Blood Cells Mol Dis 45 269 275 10.1016/j.bcmd.2010.09.004 20926322 10.1016/j.bcmd.2010.09.004 1:CAS:528:DC%2BC3cXhsV2jtLrL
    • (2010) Blood Cells Mol Dis , vol.45 , pp. 269-275
    • Liu, K.1    Xing, H.2    Xhang, S.3
  • 15
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • 12649187 1:CAS:528:DC%2BD3sXit1Sgtb4%3D
    • MA Blaskovich J Sun A Cantor, et al. 2003 Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice Cancer Res 63 1270 1279 12649187 1:CAS:528:DC%2BD3sXit1Sgtb4%3D
    • (2003) Cancer Res , vol.63 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3
  • 16
    • 0016198022 scopus 로고
    • Cucurbitacines, cytotoxic and antitumor substances from Bryonia alba L. Part II: Biological studies
    • 4480045 1:CAS:528:DyaE2MXhtFyqurs%3D
    • J Konopa A Matuszkiewicz M Hrabowska 1974 Cucurbitacines, cytotoxic and antitumor substances from Bryonia alba L. Part II: Biological studies Arzneimittelforschung 24 1741 1743 4480045 1:CAS:528:DyaE2MXhtFyqurs%3D
    • (1974) Arzneimittelforschung , vol.24 , pp. 1741-1743
    • Konopa, J.1    Matuszkiewicz, A.2    Hrabowska, M.3
  • 17
    • 0016290461 scopus 로고
    • Cucurbitacins, cytotoxic and antitumor substances from Bryonia alba L. I: Isolation and identification
    • 4479761 1:CAS:528:DyaE2MXntVartg%3D%3D
    • J Konopa J Zielinski A Matuszkiewicz 1974 Cucurbitacins, cytotoxic and antitumor substances from Bryonia alba L. I: isolation and identification Arzneimittelforschung 24 1554 1557 4479761 1:CAS:528:DyaE2MXntVartg%3D%3D
    • (1974) Arzneimittelforschung , vol.24 , pp. 1554-1557
    • Konopa, J.1    Zielinski, J.2    Matuszkiewicz, A.3
  • 18
    • 11144353961 scopus 로고    scopus 로고
    • Inhibition of nitric oxide generation by 23,24-dihydrocucurbitacin D in mouse peritoneal macrophages
    • 10.1124/jpet.103.063693 14752064 10.1124/jpet.103.063693 1:CAS:528:DC%2BD2cXjs1ygsr4%3D
    • CS Park H Lim KJ Han, et al. 2004 Inhibition of nitric oxide generation by 23,24-dihydrocucurbitacin D in mouse peritoneal macrophages J Pharmacol Exp Ther 309 705 710 10.1124/jpet.103.063693 14752064 10.1124/jpet.103.063693 1:CAS:528:DC%2BD2cXjs1ygsr4%3D
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 705-710
    • Park, C.S.1    Lim, H.2    Han, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.