Large scale preparation of midkine antisense oligonucleotides nanoliposomes by a cross-flow injection technique combined with ultrafiltration and high-pressure extrusion procedures

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 712-720

  Zhong, Jing ^a   Yao, Xing ^a   Li, Dong Li ^a   Li, Li Qin ^a   Zhou, Lin Fu ^b   Huang, Hui Lian ^a   Min, Li Shan ^a   Li, Jing ^a   Fu, Fang Fang ^b   Dai, Li Cheng ^a  

^a HUZHOU CENTRAL HOSPITAL   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Antisense oligonucleotide; HCC therapy; Large scale preparation; Liposome; Midkine

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FLUOROURACIL; LIPOSOME; MIDKINE ANTISENSE OLIGONUCLEOTIDE; NANOLIPOSOME; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL ASSAY; CELL PROLIFERATION; CONTROLLED STUDY; CROSS FLOW INJECTION TECHNIQUE; DRUG INHIBITION; DRUG RELEASE; DRUG STABILITY; FEMALE; FREEZE DRYING; HIGH PRESSURE EXTRUSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMAGE ANALYSIS; IN VITRO STUDY; LIVER CANCER; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PHARMACODYNAMICS; PRIORITY JOURNAL; REPRODUCIBILITY; STORAGE; STORAGE STABILITY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME; ULTRAFILTRATION; ZETA POTENTIAL;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYTOKINES; DRUG COMPOUNDING; DRUG STABILITY; DRUG STORAGE; FEMALE; FREEZE DRYING; HUMANS; LIPOSOMES; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OLIGONUCLEOTIDES, ANTISENSE; PARTICLE SIZE; PRESSURE; REPRODUCIBILITY OF RESULTS; ULTRAFILTRATION;

EID: 84872791062     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.10.023     Document Type: Article

References (38)

1. A.S. Abu Lila, T. Ishida, and H. Kiwada Recent advances in tumor vasculature targeting using liposomal drug delivery systems Expert Opin. Drug Deliv. 6 2009 1297 1309
2. T.J. Anchordoquy, J.F. Carpenter, and D.J. Kroll Maintenance of transfection rates and physical characterization of lipid/DNA complexes after freeze-drying and rehydration Arch. Biochem. Biophys. 348 1997 199 206
3. A.D. Bangham Properties and uses of lipid vesicles: an overview Ann. N.Y. Acad. Sci. 308 1978 2 7
4. S. Batzri, and E.D. Korn Single bilayer liposomes prepared without sonication Biochim. Biophys. Acta 298 1973 1015 1019
5. S. Chandran, A. Roy, and B. Mishra Recent trends in drug delivery systems: liposomal drug delivery system - preparation and characterisation Indian J. Exp. Biol. 35 1997 801 809
6. M.G. Carstens, K. van der Maaden, D. van der Velden, T.H. Ottenhoff, C.J. Melief, F. Ossendorp, J.A. Bouwstra, and W. Jiskoot Evaluation of the high-pressure extrusion technique as a method for sizing plasmid DNA-containing cationic liposomes J. Liposome Res. 21 2011 286 295
7. H.L. Chen, W.Q. Liang, J.B. Shao, and Z. Chen Preparation of cationic liposomes and its role in enhancing cellular uptake of antisense oligonucleotides Yao Xue Xue Bao 39 2004 72 76
8. J. Clement, K. Kiefer, A. Kimpfler, P. Garidel, and R. Peschka-Süss Large-scale production of lipoplexes with long shelf-life Eur. J. Pharm. Biopharm. 59 2005 35 43
9. L.C. Dai, X. Wang, X. Yao, Y.L. Lu, J.L. Ping, and J.F. He Antisense oligonucleotides targeting midkine induced apoptosis and increased chemosensitivity in hepatocellular carcinoma cells Acta Pharmacol. Sin. 27 2006 1630 1636
10. L.C. Dai, X. Wang, X. Yao, Y.L. Lu, J.L. Ping, and J.F. He Enhanced therapeutic effects of combined chemotherapeutic drugs and midkine antisense oligonucleotides for hepatocellular carcinoma World J. Gastroenterol. 13 2007 1989 1994
11. L.C. Dai, X. Yao, X. Wang, S.Q. Niu, L.F. Zhou, F.F. Fu, S.X. Yang, and J.L. Ping In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-antisense oligonucleotide-loaded nanoparticles World J. Gastroenterol. 15 2009 1966 1972
12. D.F. Driscoll Lipid injectable emulsions: pharmacopeial and safety issues Pharm. Res. 23 2006 1959 1969
13. M.J. Hope, M.B. Bally, G. Webb, and P. Cullis Production of large unilamellar vesicles by rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential Biochim. Biophys. Acta 812 1985 55 65
14. A. Jahn, W.N. Vreeland, D.L. DeVoe, L.E. Locascio, and M. Gaitan Microfluidic directed formation of liposomes of controlled size Langmuir 23 2007 6289 6293
15. H. Kikuchi, H. Yamauchi, and S. Hirota A polyol dilution method for mass production of liposomes J. Liposome Res. 4 1994 71 91
16. J.M. Kremer, M.W. Esker, C. Pathmamanoharan, and P.H. Wiersema Vesicles of variable diameter prepared by a modified injection method Biochemistry 16 1977 3932 3935
17. E. Lai, and J.H. van Zanten Evidence of lipoplex dissociation in liquid formulations J. Pharm. Sci. 91 2002 1225 1232
18. A. Laouini, C. Jaafar-Maalej, S. Sfar, C. Charcosset, and H. Fessi Liposome preparation using a hollow fiber membrane contactor - application to spironolactone encapsulation Int. J. Pharm. 415 2011 53 61
19. D.D. Lasic Ethanol injection Liposomes: From Physics to Application. Part 1 1993 Elsevier Amsterdam pp. 88-90
20. B. Li, S. Li, Y. Tan, D.B. Stolz, S.C. Watkins, L.H. Block, and L. Huang Lyophilization of cationic lipid-protamine-DNA (LPD) complexes J. Pharm. Sci. 89 2000 355 364
21. C. Li, and Y. Deng A novel method for the preparation of liposomes: freeze drying of monophase solutions J. Pharm. Sci. 93 2004 1403 1414
22. R.X. Lin, C.W. Tuo, Q.J. Lü, W. Zhang, and S.Q. Wang Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model Acta Pharmacol. Sin. 26 2005 762 768
23. M.R. Mozafari, C.J. Reed, C. Rostron, C. Kocum, and E. Piskin Construction of stable anionic liposome-plasmid particles using the heating method: a preliminary investigation Cell. Mol. Biol. Lett. 7 2002 923 927
24. A.R. Mohammed, V.W. Bramwell, A.G.A. Coombes, and Y. Perrie Lyophilisation and sterilization of liposomal vaccines to produce stable and sterile products Methods 40 2006 30 38
25. S.M. Mortazavi, M.R. Mohammadabadi, K. Khosravi-Darani, and M.R. Mozafari Preparation of liposomal gene therapy vectors by a scalable method without using volatile solvents or detergents J. Biotechnol. 129 2007 604 613
26. R. Naeff Feasibility of topical liposome drugs produced on an industrial scale Adv. Drug Deliv. Rev. 18 1996 343 347
27. K. Otake, T. Shimomura, and T. Goto Preparation of liposomes using an improved supercritical reverse phase evaporation method Langmuir 22 2006 2543 2550
28. P. Pradhan, J. Guan, D. Lu, P.G. Wang, L.J. Lee, and R.J. Lee A facile microfluidic method for production of liposomes Anticancer Res. 28 2008 943 947
29. J. Swarbrick, and J.C. Boylan Liposome as pharmaceutical dosage forms M. Dekker, Encyclopedia of Pharmaceutical Technology vol. 9 1994 Informa Healthcare New York 1 39
30. T. Schneider, A. Sachse, G. Rößling, and M. Brandl Large-scale production of liposomes of defined size by a new continuous high pressure extrusion device Drug Dev. Ind. Pharm. 20 1994 2787 2807
31. F. Szoka, and D. Papahadjopoulos Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation Proc. Natl. Acad. Sci. U.S.A. 75 1978 4194 4198
32. P. Stano, S. Bufali, C. Pisano, F. Bucci, M. Barbarino, M. Santaniello, P. Carminati, and P. Luigi Luisi Novel camptothecin analogue (gimatecan)-containing liposomes prepared by the ethanol injection method J. Liposome Res. 14 2004 87 109
33. L. Saunders, J. Perrin, and G. Gammack Ultrasonic irradiation of some phospholipid sols J. Pharm. Pharmacol. 14 1962 567 572
34. V.P. Torchilin Targeted pharmaceutical nanocarriers for cancer therapy and imaging AAPS J. 9 2007 E128 E147
35. S. Vemuri, and C.T. Rhodes Preparation and characterization of liposomes as therapeutic delivery systems: a review Pharm. Acta Helv. 70 1995 95 111
36. A. Wagner, K. Vorauer-Uhl, and H. Katinger Liposomes produced in a pilot scale: production, purification, and efficiency aspects Eur. J. Pharm. Biopharm. 54 2002 213 219
37. A. Wagner, M. Platzgummer, and G. Kreismayr GMP production of liposomes: a new industrial approach J. Liposome Res. 16 2006 311 319
38. O. Zumbuehl, and H.G. Weder Liposomes of controllable size in the range of 40-180 nm by defined dialysis of lipid/detergent mixed micelles Biochim. Biophys. Acta 640 1981 252 262