New bis-thiazolium analogues as potential antimalarial agents: Design, synthesis, and biological evaluation

Journal of Medicinal Chemistry

Volumn 56, Issue 2, 2013, Pages 496-509

  Caldarelli, Sergio A ^a   El Fangour, Siham ^a   Wein, Sharon ^b   Tran Van Ba, Christophe ^b   Périgaud, Christian ^a   Pellet, Alain ^c   Vial, Henri J ^b   Peyrottes, Suzanne ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT; ANTIMALARIAL AGENT; THIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG DOSE COMPARISON; DRUG SYNTHESIS; FEMALE; IC 50; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; LIPOPHILICITY; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM VINCKEI; PLASMODIUM VINCKEI INFECTION; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 84872788495     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3014585     Document Type: Article

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