Metabolic biofouling of glucose sensors in vivo: Role of tissue microhemorrhages

Journal of Diabetes Science and Technology

Volumn 5, Issue 3, 2011, Pages 583-595

  Klueh, Ulrike ^a   Liu, Zenghe ^b   Feldman, Ben ^b   Henning, Timothy P ^b   Cho, Brian ^b   Ouyang, Tianmei ^b   Kreutzer, Don ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Artificial hemorrhages; Blood clots; Continuous glucose monitoring; Implantable glucose sensor; Metabolic biofouling; Mouse; Sensor function in vivo; Temporary signal reduction; Tissue hemorrhages

Indexed keywords

GLUCOSE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOFOULING; BLEEDING; BLOOD CLOT; BLOOD CLOTTING; BLOOD GLUCOSE MONITORING; ELECTRODE; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE SENSOR; HUMAN; IMPLANTATION; IN VITRO STUDY; IN VIVO STUDY; INFORMATION PROCESSING; MOUSE; NONHUMAN; PLASMA; ANIMAL; DISEASE MODEL; EQUIPMENT DESIGN; GENETIC PROCEDURES; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; PROSTHESES AND ORTHOSES; SENSITIVITY AND SPECIFICITY; TIME;

ANIMALS; BIOFOULING; BIOSENSING TECHNIQUES; BLOOD COAGULATION; BLOOD GLUCOSE; BLOOD GLUCOSE SELF-MONITORING; DISEASE MODELS, ANIMAL; EQUIPMENT DESIGN; FEMALE; HEMORRHAGE; HUMANS; MICE; MICE, INBRED ICR; PROSTHESES AND IMPLANTS; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

EID: 84872781187     PISSN: None     EISSN: 19322968     Source Type: Journal    
DOI: 10.1177/193229681100500313     Document Type: Article

References (15)

1. Klueh U, Dorsky DI, Kreutzer DL. Enhancement of implantable glucose sensor function in vivo using gene transfer-induced neovascularization. Biomaterials. 2005;26(10):1155-1163. [PubMed] (Pubitemid 39286825)
2. Ward WK, Troupe JE. Assessment of chronically implanted subcutaneous glucose sensors in dogs: the effect of surrounding fluid masses. ASAIO J. 1999;45(6):555-561. [PubMed] (Pubitemid 30017346)
3. Klueh U, Liu Z, Ouyang T, Cho B, Feldman B, Henning TP, Kreutzer D. Blood-induced interference of glucose sensor function in vitro: implications for in vivo sensor function. J Diabetes Sci Technol. 2007;1(6):842-849. [PMC free article] [PubMed]
4. Klueh U, Kaur M, Qiao Y, Kreutzer DL. Critical role of tissue mast cells in controlling long-term glucose sensor function in vivo. Biomaterials. 2010;31(16):4540-4551. [PMC free article] [PubMed]
5. Klueh U, Liu Z, Cho B, Ouyang T, Feldman B, Henning TP, Kaur M, Kreutzer D. Continuous glucose monitoring in normal mice and mice with prediabetes and diabetes. Diabetes Technol Ther. 2006;8(3):402- 412. [PubMed]
6. Klueh U, Liu Z, Feldman B, Kreutzer D. Importance of interleukin-1 and interleukin-1 receptor antagonist in short-term glucose sensor function in vivo. J Diabetes Sci Technol. 2010;4(5):1073-1086. [PMC free article] [PubMed]
7. Hem A, Smith AJ, Solberg P. Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink. Lab Anim. 1998;32(4):364-368. [PubMed] (Pubitemid 28482470)
8. Bühling KJ, Kurzidim B, Wolf C, Wohlfarth K, Mahmoudi M, Wäscher C, Siebert G, Dudenhausen JW. Introductory experience with the continuous glucose monitoring system (CGMS; Medtronic Minimed) in detecting hyperglycemia by comparing the self-monitoring of blood glucose (SMBG) in non-pregnant women and in pregnant women with impaired glucose tolerance and gestational diabetes. Exp Clin Endocrinol Diabetes. 2004;112(10):556-560. [PubMed] (Pubitemid 39664693)
9. Djakouré-Platonoff C, Radermercker R, Reach G, Slama G, Selam JI. Accuracy of the continuous glucose monitoring system in inpatient and outpatient conditions. Diabetes Metab. 2003;29(2 Pt 1):159-162. [PubMed] (Pubitemid 36576095)
10. Feldman B, Brazg R, Schwartz S, Weinstein R. A continuous glucose sensor based on wired enzyme technology - results from a 3-day trial in patients with type 1 diabetes. Diabetes Technol Ther. 2003;5(5):769-779. [PubMed] (Pubitemid 37339539)
11. Kapitza C, Lodwig V, Obermaier K, Wientjes KJ, Hoogenberg K, Jungheim K, Heinemann L. Glucose Monitoring Study Group. Continuous glucose monitoring: reliable measurements for up to 4 days with the SCGM1 system. Diabetes Technol Ther. 2003;5(4):609-614. [PubMed] (Pubitemid 36999273)
12. Maran A, Crepaldi C, Tiengo A, Grassi G, Vitali E, Pagano G, Bistoni S, Calabrese G, Santeusanio F, Leonetti F, Ribaudo M, Di Mario U, Annuzzi G, Genovese S, Riccardi G, Previti M, Cucinotta D, Giorgino F, Bellomo A, Giorgino R, Poscia A, Varalli M. Continuous subcutaneous glucose monitoring in diabetic patients: a multicenter analysis. Diabetes Care. 2002;25(2):347-352. [PubMed] (Pubitemid 41079634)
13. Tansey MJ, Beck RW, Buckingham BA, Mauras N, Fiallo-Scharer R, Xing D, Killman C, Tamborlane WV, Ruedy KJ. Diabetes Research in Children Network (DirecNet) Study Group. Accuracy of the modified Continuous Glucose Monitoring System (CGMS) sensor in an outpatient setting: results from a diabetes research in children network (DirecNet) study. Diabetes Technol Ther. 2005;7(1):109-114. [PMC free article] [PubMed] (Pubitemid 40354580)
14. Gerritsen M, Jansen JA, Kros A, Vriezema DM, Sommerdijk NA, Nolte RJ, Lutterman JA, Van Hövell SW, Van der Gaag A. Influence of inflammatory cells and serum on the performance of implantable glucose sensors. J Biomed Mater Res. 2001;54(1):69-75. [PubMed]
15. Gifford R, Kehoe JJ, Barnes SL, Kornilayev BA, Alterman MA, Wilson GS. Protein interactions with subcutaneously implanted biosensors. Biomaterials. 2006;27(12):2587-2598. [PubMed] (Pubitemid 43115237)